Rhythm Pharmaceuticals, Inc.
MX ˙ BMV ˙ US76243J1051
SecurityMX:RYTM / Rhythm Pharmaceuticals, Inc.
InstitutionRafferty Asset Management, LLC
Latest Disclosed Ownership50,105 shares
Latest Disclosed Value $ 4,357,632
Rafferty Asset Management, LLC reports 9.76% decrease in ownership of RYTM / Rhythm Pharmaceuticals, Inc.

On May 15, 2026 - Rafferty Asset Management, LLC filed a 13F-HR form disclosing ownership of 50,105 shares of Rhythm Pharmaceuticals, Inc. (MX:RYTM) valued at $4,357,632 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 55,526 shares of Rhythm Pharmaceuticals, Inc.. This represents a change in shares of -9.76% during the quarter.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 50,105 -5,421 -9.76 4,358 -26.69 0.0177
2026-02-13 2025-12-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 55,526 -208 -0.37 5,944 5.60 0.0205
2025-11-12 2025-09-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 55,734 4,123 7.99 5,629 72.59 0.0183
2025-08-14 2025-06-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 51,611 -6,121 -10.60 3,261 6.64 0.0108
2025-05-14 2025-03-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 57,732 7,338 14.56 3,058 8.40 0.0130
2025-02-14 2024-12-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 50,394 -14,182 -21.96 2,821 -16.61 0.0100
2024-11-13 2024-09-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 64,576 -7,986 -11.01 3,383 13.56 0.0116
2024-08-13 2024-06-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 72,562 -146,095 -66.81 2,979 -68.56 0.0111
2024-05-13 2024-03-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 218,657 97,003 79.74 9,474 69.42 0.0353
2024-02-13 2023-12-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 121,654 -41,150 -25.28 5,592 49.84 0.0236
2023-11-13 2023-09-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 162,804 -96,540 -37.22 3,732 -12.72 0.0219
2023-08-11 2023-06-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 259,344 4,134 1.62 4,277 -6.06 0.0241
2023-05-11 2023-03-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 255,210 -50,803 -16.60 4,553 -48.92 0.0309
2023-02-13 2022-12-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 306,013 43,725 16.67 8,911 38.67 0.0746
2022-11-14 2022-09-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 262,288 262,288 6,426 0.0684
2022-05-13 2022-03-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 0 -111,594 -100.00 0 -100.00
2022-02-10 2021-12-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 111,594 28,740 34.69 1,114 2.96 0.0059
2021-11-10 2021-09-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 82,854 -167 -0.20 1,082 -33.46 0.0074
2021-08-10 2021-06-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 83,021 -38,646 -31.76 1,626 -37.17 0.0102
2021-05-10 2021-03-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 121,667 111,888 1,144.17 2,588 789.35 0.0177
2021-02-10 2020-12-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 9,779 -902 -8.44 291 25.97 0.0028
2020-11-13 2020-09-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 10,681 10,681 231 0.0028
2020-05-15 2020-03-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 0 -20,847 -100.00 0 -100.00
2020-02-10 2019-12-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 20,847 -7,134 -25.50 479 -20.70 0.0074
2019-11-14 2019-09-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 27,981 10,794 62.80 604 59.79 0.0094
2019-08-09 2019-06-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 17,187 3,071 21.76 378 -2.33 0.0066
2019-05-15 2019-03-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 14,116 14,116 387 0.0062
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.