Rhythm Pharmaceuticals, Inc.
MX ˙ BMV ˙ US76243J1051
SecurityMX:RYTM / Rhythm Pharmaceuticals, Inc.
InstitutionLegal & General Group Plc
Latest Disclosed Ownership47,032 shares
Latest Disclosed Value $ 4,090,372
Legal & General Group Plc reports 14.60% decrease in ownership of RYTM / Rhythm Pharmaceuticals, Inc.

On May 8, 2026 - Legal & General Group Plc filed a 13F-HR form disclosing ownership of 47,032 shares of Rhythm Pharmaceuticals, Inc. (MX:RYTM) valued at $4,090,372 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 9, 2026 disclosing 55,075 shares of Rhythm Pharmaceuticals, Inc.. This represents a change in shares of -14.60% during the quarter.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

Upgrade to unlock premium data and export to Excel .

Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-08 2026-03-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 47,032 -8,043 -14.60 4,090 -30.62 0.0009
2026-02-09 2025-12-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 55,075 -2,301 -4.01 5,895 1.74 0.0013
2025-11-13 2025-09-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 57,376 4,695 8.91 5,794 74.10 0.0013
2025-08-12 2025-06-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 52,681 1,523 2.98 3,329 22.85 0.0008
2025-05-15 2025-03-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 51,158 -645 -1.25 2,710 -6.55 0.0007
2025-02-13 2024-12-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 51,803 951 1.87 2,900 8.82 0.0008
2025-02-28 2024-09-30 13F/A-2 RHYTHM PHARMACEUTICALS COM 76243J105 50,852 1,081 2.17 2,664 30.40 0.0007
2024-11-14 2024-09-30 13F/A-1 RHYTHM PHARMACEUTICALS COM 76243J105 56,047 2,521 2,936 0.0006
2024-11-14 2024-09-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 56,047 2,521 2,936 0.0003
2025-05-29 2024-06-30 13F/A-1 RHYTHM PHARMACEUTICALS COM 76243J105 49,771 2,355 4.97 2,044 -0.54 0.0006
2024-08-14 2024-06-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 53,526 6,110 2,198 0.0005
2025-05-29 2024-03-31 13F/A-2 RHYTHM PHARMACEUTICALS COM 76243J105 47,416 588 1.26 2,055 -4.55 0.0006
2024-07-01 2024-03-31 13F/A-1 RHYTHM PHARMACEUTICALS COM 76243J105 47,416 588 2,055 0.0005
2024-05-14 2024-03-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 47,416 588 2,055 0.0002
2025-05-29 2023-12-31 13F/A-1 RHYTHM PHARMACEUTICALS COM 76243J105 46,828 3,674 8.51 2,153 117.59 0.0007
2024-02-15 2023-12-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 46,828 3,674 2,153 0.0006
2023-11-14 2023-09-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 43,154 501 1.17 989 40.68 0.0003
2023-08-14 2023-06-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 42,653 25,534 149.16 703 130.49 0.0002
2023-05-15 2023-03-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 17,119 2,323 15.70 305 -29.07 0.0001
2023-02-14 2022-12-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 14,796 5,028 51.47 431 79.92 0.0002
2022-11-14 2022-09-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 9,768 -2,479 -20.24 239 368.63 0.0001
2022-08-22 2022-06-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 12,247 -1,016 -7.66 51 -66.67 0.0000
2022-05-16 2022-03-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 13,263 0 0.00 153 15.91 0.0000
2022-02-14 2021-12-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 13,263 0 0.00 132 -23.70 0.0000
2021-11-15 2021-09-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 13,263 6,811 105.56 173 36.22 0.0001
2021-08-12 2021-06-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 6,452 -4 -0.06 127 -7.30 0.0000
2021-05-17 2021-03-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 6,456 1,335 26.07 137 -9.87 0.0001
2021-02-12 2020-12-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 5,121 -56 -1.08 152 35.71 0.0001
2020-11-13 2020-09-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 5,177 -1,463 -22.03 112 -24.32 0.0001
2020-08-14 2020-06-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 6,640 799 13.68 148 74.12 0.0001
2020-05-14 2020-03-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 5,841 -1,303 -18.24 85 -48.17 0.0000
2020-02-13 2019-12-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 7,144 2,927 69.41 164 76.34 0.0001
2019-08-14 2019-06-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 4,217 1,362 47.71 93 17.72 0.0001
2019-05-15 2019-03-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 2,855 180 6.73 79 11.27 0.0000
2019-02-15 2018-12-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 2,675 0 0.00 71 -8.97 0.0001
2018-11-20 2018-09-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 2,675 850 46.58 78 36.84 0.0001
2018-08-10 2018-06-30 13F RHYTHM PHARMACEUTICALS COM 76243J105 1,825 383 26.56 57 96.55 0.0000
2018-05-17 2018-03-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 1,442 0 0.00 29 -30.95 0.0000
2018-02-13 2017-12-31 13F RHYTHM PHARMACEUTICALS COM 76243J105 1,442 1,442 42 0.0000
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.