Revolution Medicines, Inc.
MX ˙ BMV ˙ US76155X1000
SecurityMX:RVMD / Revolution Medicines, Inc.
InstitutionRenaissance Technologies Llc
ManagerJames Simons
Latest Disclosed Ownership6,200 shares
Latest Disclosed Value $ 602,950
Renaissance Technologies Llc ownership in RVMD / Revolution Medicines, Inc.

On May 14, 2026 - Renaissance Technologies Llc filed a 13F-HR form disclosing ownership of 6,200 shares of Revolution Medicines, Inc. (MX:RVMD) valued at $602,950 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 12, 2026 disclosing 0 shares of Revolution Medicines, Inc..

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-14 2026-03-31 13F REVOLUTION MEDICINES COM 76155X100 6,200 6,200 603 0.0009
2026-02-12 2025-12-31 13F REVOLUTION MEDICINES COM 76155X100 0 -253,104 -100.00 0 -100.00
2025-11-13 2025-09-30 13F REVOLUTION MEDICINES COM 76155X100 253,104 9,600 3.94 11,820 31.94 0.0156
2025-08-13 2025-06-30 13F REVOLUTION MEDICINES COM 76155X100 243,504 100,700 70.52 8,959 77.42 0.0119
2025-05-14 2025-03-31 13F REVOLUTION MEDICINES COM 76155X100 142,804 142,804 5,050 0.0076
2023-08-11 2023-06-30 13F REVOLUTION MEDICINES COM 76155X100 0 -43,300 -100.00 0 0.0000
2023-05-12 2023-03-31 13F REVOLUTION MEDICINES COM 76155X100 43,300 43,300 1 0.0012
2023-02-13 2022-12-31 13F REVOLUTION MEDICINES COM 76155X100 0 -68,900 -100.00 0 -100.00
2022-11-14 2022-09-30 13F REVOLUTION MEDICINES COM 76155X100 68,900 68,900 1,359 0.0019
2022-05-13 2022-03-31 13F REVOLUTION MEDICINES COM 76155X100 0 -55,100 -100.00 0 -100.00
2022-02-11 2021-12-31 13F REVOLUTION MEDICINES COM 76155X100 55,100 55,100 1,387 0.0017
2021-11-12 2021-09-30 13F REVOLUTION MEDICINES COM 76155X100 0 -22,900 -100.00 0 -100.00
2021-08-13 2021-06-30 13F REVOLUTION MEDICINES COM 76155X100 22,900 13,300 138.54 727 65.23 0.0009
2021-05-13 2021-03-31 13F REVOLUTION MEDICINES COM 76155X100 9,600 9,600 440 0.0005
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.