Pacific Biosciences of California, Inc.
MX ˙ BMV ˙ US69404D1081
SecurityMX:PACB / Pacific Biosciences of California, Inc.
InstitutionCasdin Capital, LLC
Latest Disclosed Ownership723,767 shares
Latest Disclosed Value $ 955,372
Casdin Capital, LLC reports 82.86% decrease in ownership of PACB / Pacific Biosciences of California, Inc.

On May 15, 2026 - Casdin Capital, LLC filed a 13F-HR form disclosing ownership of 723,767 shares of Pacific Biosciences of California, Inc. (MX:PACB) valued at $955,372 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 4,223,767 shares of Pacific Biosciences of California, Inc.. This represents a change in shares of -82.86% during the quarter.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 723,767 -3,500,000 -82.86 955 -87.91 0.0723
2026-02-17 2025-12-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 4,223,767 3,500,000 483.58 7,898 752.92 0.4906
2025-11-14 2025-09-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 723,767 0 0.00 926 3.23 0.0772
2025-08-14 2025-06-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 723,767 0 0.00 897 5.04 0.0817
2025-05-15 2025-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 723,767 -312,092 -30.13 854 -54.93 0.0698
2025-02-14 2024-12-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 1,035,859 0 0.00 1,896 7.67 0.1261
2024-11-14 2024-09-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 1,035,859 0 0.00 1,761 24.03 0.1174
2024-10-18 2024-06-30 13F/A-1 PACIFIC BIOSCIENCES CALIF IN COM 69404D108 1,035,859 0 0.00 1,419 -63.47 0.1084
2024-08-14 2024-06-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 1,035,859 0 1,419 0.1088
2024-05-15 2024-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 1,035,859 0 0.00 3,884 -61.78 0.2888
2024-02-14 2023-12-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 1,035,859 0 0.00 10,162 17.48 0.9975
2023-11-14 2023-09-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 1,035,859 1,035,859 8,649 0.9573
2022-08-15 2022-06-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 0 -7,990,652 -100.00 0 -100.00
2022-05-16 2022-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 7,990,652 0 0.00 72,715 -55.52 3.2604
2022-02-14 2021-12-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 7,990,652 0 0.00 163,489 -19.92 4.6079
2021-11-15 2021-09-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 7,990,652 2,990,652 59.81 204,161 16.76 5.0818
2021-08-16 2021-06-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 5,000,000 0 0.00 174,850 4.98 4.4385
2021-05-17 2021-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 5,000,000 0 0.00 166,550 28.41 4.9604
2021-02-16 2020-12-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 5,000,000 500,000 11.11 129,700 192.02 3.8425
2020-11-16 2020-09-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 4,500,000 4,500,000 44,415 1.9887
2017-11-14 2017-09-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 0 -300,000 -100.00 0 -100.00
2017-08-14 2017-06-30 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 300,000 -400,000 -57.14 1,068 -70.49 0.3950
2017-05-15 2017-03-31 13F PACIFIC BIOSCIENCES CALIF IN COM 69404D108 700,000 700,000 3,619 2.1350
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.