OPKO Health, Inc.
MX ˙ BMV ˙ US68375N1037
SecurityMX:OPK / OPKO Health, Inc.
InstitutionRK Asset Management, LLC
Latest Disclosed Ownership40,485 shares
Latest Disclosed Value $ 51
RK Asset Management, LLC ownership in OPK / OPKO Health, Inc.

On January 5, 2026 - RK Asset Management, LLC filed a 13F-HR form disclosing ownership of 40,485 shares of OPKO Health, Inc. (MX:OPK) valued at $51 USD as of December 31, 2025. The entity filed a previous 13F-HR on October 14, 2025 disclosing 40,485 shares of OPKO Health, Inc..

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-01-05 2025-12-31 13F OPKO HEALTH COM 68375N103 40,485 0 0.00 0 0.0481
2025-10-14 2025-09-30 13F OPKO HEALTH COM 68375N103 40,485 0 0.00 0 0.0573
2025-07-18 2025-06-30 13F OPKO HEALTH COM 68375N103 40,485 0 0.00 0 0.0511
2025-04-02 2025-03-31 13F OPKO HEALTH COM 68375N103 40,485 4,000 10.96 0 0.0618
2025-01-03 2024-12-31 13F OPKO HEALTH COM 68375N103 36,485 -200 -0.55 0 0.0442
2024-10-07 2024-09-30 13F OPKO HEALTH COM 68375N103 36,685 0 0.00 0 0.0423
2024-08-02 2024-06-30 13F OPKO HEALTH COM 68375N103 36,685 0 0.00 0 0.0397
2024-04-03 2024-03-31 13F OPKO HEALTH COM 68375N103 36,685 0 0.00 0 0.0358
2024-01-09 2023-12-31 13F OPKO HEALTH COM 68375N103 36,685 0 0.00 0 0.0456
2023-10-10 2023-09-30 13F OPKO HEALTH COM 68375N103 36,685 0 0.00 0 0.0552
2023-07-06 2023-06-30 13F OPKO HEALTH COM 68375N103 36,685 0 0.00 0 0.0740
2023-04-03 2023-03-31 13F OPKO HEALTH COM 68375N103 36,685 0 0.00 0 -100.00 0.0534
2023-01-03 2022-12-31 13F OPKO HEALTH COM 68375N103 36,685 0 0.00 0 -100.00 0.0441
2022-04-11 2022-03-31 13F OPKO HEALTH COM 68375N103 36,685 0 0.00 126 -28.41 0.1222
2022-01-05 2021-12-31 13F OPKO HEALTH COM 68375N103 36,685 36,685 176 0.1553
2021-04-05 2021-03-31 13F OPKO HEALTH COM 68375N103 0 -1,171,274 -100.00 0 -100.00
2020-01-06 2019-12-31 13F OPKO HEALTH COM 68375N103 1,171,274 -32,426 -2.69 1,722 -31.56 1.6064
2019-10-10 2019-09-30 13F OPKO HEALTH COM 68375N103 1,203,700 23,428 1.98 2,516 -12.64 2.4377
2019-07-01 2019-06-30 13F OPKO HEALTH COM 68375N103 1,180,272 0 0.00 2,880 -6.52 2.7646
2019-04-01 2019-03-31 13F OPKO HEALTH COM 68375N103 1,180,272 198,047 20.16 3,081 4.23 2.9568
2019-01-07 2018-12-31 13F OPKO HEALTH COM 68375N103 982,225 -62,668 -6.00 2,956 -18.23 2.8437
2018-10-11 2018-09-30 13F OPKO HEALTH COM 68375N103 1,044,893 18,875 1.84 3,615 -25.03 3.1795
2018-07-03 2018-06-30 13F/A-1 OPKO HEALTH COM 68375N103 1,026,018 177,961 20.98 4,822 79.39 4.3189
2018-07-02 2018-06-30 13F OPKO HEALTH COM 68375N103 1,026,018 177,961 4,822
2018-04-09 2018-03-31 13F OPKO HEALTH COM 68375N103 848,057 -84,695 -9.08 2,688 -41.18 2.6688
2018-01-04 2017-12-31 13F OPKO HEALTH COM 68375N103 932,752 72,209 8.39 4,570 -22.58 3.8568
2017-10-06 2017-09-30 13F OPKO HEALTH COM 68375N103 860,543 -46,188 -5.09 5,903 -1.06 5.1418
2017-07-07 2017-06-30 13F OPKO HEALTH COM 68375N103 906,731 19,012 2.14 5,966 -16.00 5.0057
2017-04-17 2017-03-31 13F OPKO HEALTH COM 68375N103 887,719 3,300 0.37 7,102 -13.65 5.8283
2017-01-09 2016-12-31 13F OPKO HEALTH COM 68375N103 884,419 33 0.00 8,225 -12.18 6.5896
2016-10-11 2016-09-30 13F OPKO HEALTH COM 68375N103 884,386 -38,231 -4.14 9,366 8.69 8.4174
2016-07-14 2016-06-30 13F OPKO HEALTH COM 68375N103 922,617 -13,205 -1.41 8,617 -11.38 7.6957
2016-04-06 2016-03-31 13F OPKO HEALTH COM 68375N103 935,822 10,960 1.19 9,723 4.60 8.1232
2016-01-06 2015-12-31 13F/A-1 OPKO HEALTH COM 68375N103 924,862 5,348 0.58 9,295 20.21 7.9637
2016-01-06 2015-12-31 13F OPKO HEALTH COM 68375N103 924,862 9,295
2015-10-07 2015-09-30 13F OPKO HEALTH COM 68375N103 919,514 919,514 7,732 6.7421
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.