OPKO Health, Inc.
MX ˙ BMV ˙ US68375N1037
SecurityMX:OPK / OPKO Health, Inc.
InstitutionLegal & General Group Plc
Latest Disclosed Ownership343,474 shares
Latest Disclosed Value $ 391,561
Legal & General Group Plc reports 24.22% decrease in ownership of OPK / OPKO Health, Inc.

On May 8, 2026 - Legal & General Group Plc filed a 13F-HR form disclosing ownership of 343,474 shares of OPKO Health, Inc. (MX:OPK) valued at $391,561 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 9, 2026 disclosing 453,265 shares of OPKO Health, Inc.. This represents a change in shares of -24.22% during the quarter.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-08 2026-03-31 13F OPKO HEALTH COM 68375N103 343,474 -109,791 -24.22 392 -31.52 0.0001
2026-02-09 2025-12-31 13F OPKO HEALTH COM 68375N103 453,265 66,428 17.17 571 -4.52 0.0001
2025-11-13 2025-09-30 13F OPKO HEALTH COM 68375N103 386,837 31,155 8.76 598 27.51 0.0001
2025-08-12 2025-06-30 13F OPKO HEALTH COM 68375N103 355,682 5,584 1.59 469 -19.28 0.0001
2025-05-15 2025-03-31 13F OPKO HEALTH COM 68375N103 350,098 -20,340 -5.49 581 6.80 0.0002
2025-02-13 2024-12-31 13F OPKO HEALTH COM 68375N103 370,438 -19,866 -5.09 545 -6.37 0.0001
2025-02-28 2024-09-30 13F/A-2 OPKO HEALTH COM 68375N103 390,304 -22,798 -5.52 582 12.60 0.0002
2024-11-14 2024-09-30 13F/A-1 OPKO HEALTH COM 68375N103 445,616 -22,798 664 0.0001
2024-11-14 2024-09-30 13F OPKO HEALTH COM 68375N103 445,616 -22,798 664 0.0001
2025-05-29 2024-06-30 13F/A-1 OPKO HEALTH COM 68375N103 413,102 -5,500 -1.31 516 2.79 0.0001
2024-08-14 2024-06-30 13F OPKO HEALTH COM 68375N103 468,414 49,812 586 0.0001
2025-05-29 2024-03-31 13F/A-2 OPKO HEALTH COM 68375N103 418,602 0 0.00 502 -20.57 0.0001
2024-07-01 2024-03-31 13F/A-1 OPKO HEALTH COM 68375N103 418,602 0 502 0.0001
2024-05-14 2024-03-31 13F OPKO HEALTH COM 68375N103 418,602 0 502 0.0001
2025-05-29 2023-12-31 13F/A-1 OPKO HEALTH COM 68375N103 418,602 0 0.00 632 -5.53 0.0002
2024-02-15 2023-12-31 13F OPKO HEALTH COM 68375N103 418,602 0 632 0.0002
2023-11-14 2023-09-30 13F OPKO HEALTH COM 68375N103 418,602 -4,209 -1.00 670 -27.04 0.0002
2023-08-14 2023-06-30 13F OPKO HEALTH COM 68375N103 422,811 -1,592 -0.38 918 48.14 0.0003
2023-05-15 2023-03-31 13F OPKO HEALTH COM 68375N103 424,403 25,428 6.37 620 24.30 0.0002
2023-02-14 2022-12-31 13F OPKO HEALTH COM 68375N103 398,975 22,632 6.01 499 -30.06 0.0002
2022-11-14 2022-09-30 13F OPKO HEALTH COM 68375N103 376,343 29,143 8.39 712 -18.91 0.0003
2022-08-22 2022-06-30 13F OPKO HEALTH COM 68375N103 347,200 -3,055 -0.87 878 -27.14 0.0003
2022-05-16 2022-03-31 13F OPKO HEALTH COM 68375N103 350,255 6,716 1.95 1,205 -27.06 0.0004
2022-02-14 2021-12-31 13F OPKO HEALTH COM 68375N103 343,539 -3,833 -1.10 1,652 30.28 0.0005
2021-11-15 2021-09-30 13F OPKO HEALTH COM 68375N103 347,372 90,502 35.23 1,268 21.92 0.0004
2021-08-12 2021-06-30 13F OPKO HEALTH COM 68375N103 256,870 4,548 1.80 1,040 -3.97 0.0003
2021-05-17 2021-03-31 13F OPKO HEALTH COM 68375N103 252,322 7,610 3.11 1,083 12.11 0.0004
2021-02-12 2020-12-31 13F OPKO HEALTH COM 68375N103 244,712 -47,462 -16.24 966 -10.39 0.0004
2020-11-13 2020-09-30 13F OPKO HEALTH COM 68375N103 292,174 23,883 8.90 1,078 17.81 0.0005
2020-08-14 2020-06-30 13F OPKO HEALTH COM 68375N103 268,291 13,422 5.27 915 168.33 0.0004
2020-05-14 2020-03-31 13F OPKO HEALTH COM 68375N103 254,869 -15,549 -5.75 341 -14.11 0.0002
2020-02-13 2019-12-31 13F OPKO HEALTH COM 68375N103 270,418 140,588 108.29 397 25.63 0.0002
2019-08-14 2019-06-30 13F OPKO HEALTH COM 68375N103 129,830 5,137 4.12 316 -3.07 0.0002
2019-05-15 2019-03-31 13F OPKO HEALTH COM 68375N103 124,693 4,864 4.06 326 -9.70 0.0002
2019-02-15 2018-12-31 13F OPKO HEALTH COM 68375N103 119,829 6,540 5.77 361 -7.91 0.0003
2018-11-20 2018-09-30 13F OPKO HEALTH COM 68375N103 113,289 0 0.00 392 -26.32 0.0003
2018-08-10 2018-06-30 13F OPKO HEALTH COM 68375N103 113,289 -67,314 -37.27 532 -6.99 0.0004
2018-05-17 2018-03-31 13F OPKO HEALTH COM 68375N103 180,603 -28,909 -13.80 572 -44.25 0.0004
2018-02-13 2017-12-31 13F OPKO HEALTH COM 68375N103 209,512 67,977 48.03 1,026 5.66 0.0007
2017-11-09 2017-09-30 13F OPKO HEALTH COM 68375N103 141,535 21,017 17.44 971 22.45 0.0007
2017-08-03 2017-06-30 13F OPKO HEALTH COM 68375N103 120,518 8,845 7.92 793 -11.20 0.0006
2017-05-12 2017-03-31 13F OPKO HEALTH COM 68375N103 111,673 76,487 217.38 893 173.09 0.0008
2017-02-13 2016-12-31 13F OPKO HEALTH COM 68375N103 35,186 4,373 14.19 327 0.00 0.0003
2016-10-12 2016-09-30 13F OPKO HEALTH COM 68375N103 30,813 4,945 19.12 327 35.12 0.0003
2016-08-16 2016-06-30 13F OPKO HEALTH COM 68375N103 25,868 -619 -2.34 242 -12.00 0.0003
2016-05-16 2016-03-31 13F OPKO HEALTH COM 68375N103 26,487 7,234 37.57 275 42.49 0.0003
2016-02-16 2015-12-31 13F OPKO HEALTH COM 68375N103 19,253 -8,172 -29.80 193 -16.81 0.0002
2015-11-13 2015-09-30 13F OPKO HEALTH COM 68375N103 27,425 10,853 65.49 232 -12.45 0.0003
2015-07-31 2015-06-30 13F OPKO HEALTH COM 68375N103 16,572 -20,047 -54.74 265 -50.19 0.0003
2015-05-14 2015-03-31 13F OPKO HEALTH COM 68375N103 36,619 7,243 24.66 532 80.95 0.0006
2015-02-20 2014-12-31 13F/A-1 OPKO HEALTH COM 68375N103 29,376 -722 -2.40 294 13.51 0.0003
2015-02-17 2014-12-31 13F OPKO HEALTH COM 68375N103 29,376 -722 294 0.0004
2014-11-14 2014-09-30 13F OPKO HEALTH COM 68375N103 30,098 30,098 259 0.0003
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.