Medpace Holdings, Inc.
MX ˙ BMV ˙ US58506Q1094
SecurityMX:MEDP / Medpace Holdings, Inc.
InstitutionTwo Sigma Advisers, Lp
Latest Disclosed Ownership40,960 shares
Latest Disclosed Value $ 23,005,184
Two Sigma Advisers, Lp reports 53.56% decrease in ownership of MEDP / Medpace Holdings, Inc.

On February 17, 2026 - Two Sigma Advisers, Lp filed a 13F-HR form disclosing ownership of 40,960 shares of Medpace Holdings, Inc. (MX:MEDP) valued at $23,005,184 USD as of December 31, 2025. The entity filed a previous 13F-HR on November 14, 2025 disclosing 88,200 shares of Medpace Holdings, Inc.. This represents a change in shares of -53.56% during the quarter.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-02-17 2025-12-31 13F MEDPACE HLDGS COM 58506Q109 40,960 -47,240 -53.56 23,005 -49.27 0.0447
2025-11-14 2025-09-30 13F MEDPACE HLDGS COM 58506Q109 88,200 -190,200 -68.32 45,349 -48.10 0.0908
2025-08-14 2025-06-30 13F MEDPACE HLDGS COM 58506Q109 278,400 33,900 13.87 87,379 17.29 0.1791
2025-05-15 2025-03-31 13F MEDPACE HLDGS COM 58506Q109 244,500 32,000 15.06 74,497 5.52 0.1677
2025-02-14 2024-12-31 13F MEDPACE HLDGS COM 58506Q109 212,500 24,100 12.79 70,599 12.26 0.1634
2024-11-14 2024-09-30 13F MEDPACE HLDGS COM 58506Q109 188,400 8,100 4.49 62,888 -15.31 0.1473
2024-08-14 2024-06-30 13F MEDPACE HLDGS COM 58506Q109 180,300 29,500 19.56 74,257 21.84 0.1656
2024-05-15 2024-03-31 13F MEDPACE HLDGS COM 58506Q109 150,800 -7,200 -4.56 60,946 25.84 0.1412
2024-02-14 2023-12-31 13F MEDPACE HLDGS COM 58506Q109 158,000 -26,600 -14.41 48,432 8.35 0.1134
2023-11-14 2023-09-30 13F MEDPACE HLDGS COM 58506Q109 184,600 101,800 122.95 44,697 124.77 0.1145
2023-08-14 2023-06-30 13F MEDPACE HLDGS COM 58506Q109 82,800 21,800 35.74 19,886 73.36 0.0506
2023-05-15 2023-03-31 13F MEDPACE HLDGS COM 58506Q109 61,000 29,500 93.65 11,471 71.46 0.0296
2023-02-14 2022-12-31 13F MEDPACE HLDGS COM 58506Q109 31,500 8,800 38.77 6,691 87.50 0.0187
2022-11-14 2022-09-30 13F MEDPACE HLDGS COM 58506Q109 22,700 -5,900 -20.63 3,568 -16.65 0.0103
2022-08-15 2022-06-30 13F MEDPACE HLDGS COM 58506Q109 28,600 -23,400 -45.00 4,281 -49.68 0.0121
2022-05-16 2022-03-31 13F MEDPACE HLDGS COM 58506Q109 52,000 -28,800 -35.64 8,507 -51.62 0.0226
2022-02-14 2021-12-31 13F MEDPACE HLDGS COM 58506Q109 80,800 24,300 43.01 17,585 64.44 0.0440
2021-11-15 2021-09-30 13F MEDPACE HLDGS COM 58506Q109 56,500 21,000 59.15 10,694 70.56 0.0277
2021-08-16 2021-06-30 13F MEDPACE HLDGS COM 58506Q109 35,500 6,300 21.58 6,270 30.90 0.0165
2021-05-17 2021-03-31 13F MEDPACE HLDGS COM 58506Q109 29,200 -11,000 -27.36 4,790 -14.40 0.0132
2021-02-16 2020-12-31 13F MEDPACE HLDGS COM 58506Q109 40,200 -12,800 -24.15 5,596 -5.52 0.0150
2020-11-16 2020-09-30 13F MEDPACE HLDGS COM 58506Q109 53,000 300 0.57 5,923 20.83 0.0169
2020-09-15 2020-06-30 13F/A-1 MEDPACE HLDGS COM 58506Q109 52,700 1,600 3.13 4,902 30.72 0.0144
2020-08-14 2020-06-30 13F MEDPACE HLDGS COM 58506Q109 52,700 1,600 4,902 14,165.1520
2020-05-15 2020-03-31 13F MEDPACE HLDGS COM 58506Q109 51,100 -15,400 -23.16 3,750 -32.92 0.0144
2020-02-14 2019-12-31 13F MEDPACE HLDGS COM 58506Q109 66,500 -44,400 -40.04 5,590 -40.02 0.0130
2019-11-14 2019-09-30 13F MEDPACE HLDGS COM 58506Q109 110,900 -3,100 -2.72 9,320 24.97 0.0228
2019-08-14 2019-06-30 13F MEDPACE HLDGS COM 58506Q109 114,000 -66,500 -36.84 7,458 -29.93 0.0186
2019-05-15 2019-03-31 13F MEDPACE HLDGS COM 58506Q109 180,500 -248,200 -57.90 10,644 -53.09 0.0268
2019-02-14 2018-12-31 13F MEDPACE HLDGS COM 58506Q109 428,700 48,800 12.85 22,691 -0.30 0.0620
2018-11-14 2018-09-30 13F MEDPACE HLDGS COM 58506Q109 379,900 129,800 51.90 22,760 111.64 0.0555
2018-08-14 2018-06-30 13F MEDPACE HLDGS COM 58506Q109 250,100 153,100 157.84 10,754 217.60 0.0289
2018-05-15 2018-03-31 13F MEDPACE HLDGS COM 58506Q109 97,000 46,462 91.93 3,386 84.72 0.0092
2018-02-14 2017-12-31 13F MEDPACE HLDGS COM 58506Q109 50,538 23,838 89.28 1,833 115.14 0.0049
2017-11-14 2017-09-30 13F MEDPACE HLDGS COM 58506Q109 26,700 26,700 852 0.0024
2017-05-15 2017-03-31 13F MEDPACE HLDGS COM 58506Q109 0 -12,700 -100.00 0 -100.00
2017-02-14 2016-12-31 13F MEDPACE HLDGS COM 58506Q109 12,700 -8,200 -39.23 458 -26.60 0.0018
2016-11-14 2016-09-30 13F MEDPACE HLDGS COM 58506Q109 20,900 20,900 624 0.0027
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.