Arrowhead Pharmaceuticals, Inc.
MX ˙ BMV ˙ US04280A1007
SecurityMX:ARWR / Arrowhead Pharmaceuticals, Inc.
InstitutionNorthern Trust Corp
Latest Disclosed Ownership1,655,837 shares
Latest Disclosed Value $ 103,820,980
Northern Trust Corp reports 23.00% increase in ownership of ARWR / Arrowhead Pharmaceuticals, Inc.

On May 14, 2026 - Northern Trust Corp filed a 13F-HR form disclosing ownership of 1,655,837 shares of Arrowhead Pharmaceuticals, Inc. (MX:ARWR) valued at $103,820,980 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 1,346,257 shares of Arrowhead Pharmaceuticals, Inc.. This represents a change in shares of 23.00% during the quarter.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-14 2026-03-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,655,837 309,580 23.00 103,821 16.16 0.0028
2026-02-17 2025-12-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,346,257 34,667 2.64 89,378 97.58 0.0114
2025-11-14 2025-09-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,311,590 39,524 3.11 45,237 125.08 0.0058
2025-08-13 2025-06-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,272,066 61,253 5.06 20,099 30.29 0.0028
2025-05-13 2025-03-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,210,813 -273,606 -18.43 15,426 -44.73 0.0023
2025-02-14 2024-12-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,484,419 151,654 11.38 27,907 8.10 0.0040
2024-11-13 2024-09-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,332,765 10,047 0.76 25,816 -24.91 0.0042
2024-08-14 2024-06-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,322,718 22,069 1.70 34,377 -7.58 0.0058
2024-05-14 2024-03-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,300,649 71,034 5.78 37,199 -1.14 0.0064
2024-02-13 2023-12-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,229,615 -36,986 -2.92 37,626 10.56 0.0068
2023-11-13 2023-09-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,266,601 -31,682 -2.44 34,034 -26.49 0.0066
2023-08-11 2023-06-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,298,283 -21,709 -1.64 46,297 38.09 0.0089
2023-05-15 2023-03-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,319,992 36,192 2.82 33,528 -35.61 0.0066
2023-02-13 2022-12-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,283,800 4,744 0.37 52,071 23.18 0.0109
2022-11-14 2022-09-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,279,056 -17,087 -1.32 42,273 -7.37 0.0097
2022-08-12 2022-06-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,296,143 -89,251 -6.44 45,637 -28.37 0.0098
2022-05-13 2022-03-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,385,394 -36,755 -2.58 63,715 -32.43 0.0112
2022-02-08 2021-12-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,422,149 -21,802 -1.51 94,288 4.60 0.0154
2021-11-15 2021-09-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,443,951 -47,087 -3.16 90,145 -27.00 0.0160
2021-08-13 2021-06-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,491,038 -55,030 -3.56 123,488 20.45 0.0218
2021-05-12 2021-03-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,546,068 -12,357 -0.79 102,521 -14.26 0.0191
2021-02-11 2020-12-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,558,425 -36,883 -2.31 119,578 74.07 0.0233
2020-11-16 2020-09-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,595,308 -89,454 -5.31 68,695 -5.59 0.0151
2020-08-14 2020-06-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,684,762 65,577 4.05 72,765 56.20 0.0172
2020-05-14 2020-03-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,619,185 66,478 4.28 46,584 -52.70 0.0134
2020-02-14 2019-12-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,552,707 268,371 20.90 98,489 172.12 0.0220
2019-11-13 2019-09-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,284,336 27,136 2.16 36,193 8.64 0.0087
2019-08-13 2019-06-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,257,200 61,133 5.11 33,315 51.79 0.0079
2019-05-13 2019-03-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,196,067 107,755 9.90 21,948 62.37 0.0054
2019-02-12 2018-12-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,088,312 -20,952 -1.89 13,517 -36.44 0.0038
2018-11-14 2018-09-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,109,264 45,765 4.30 21,265 47.02 0.0052
2018-09-18 2018-06-30 13F/A-1 ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,063,499 841,982 380.10 14,464 805.70 0.0037
2018-08-14 2018-06-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 1,029,693 808,176 14,004
2018-05-09 2018-03-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 221,517 24,932 12.68 1,597 120.58 0.0004
2018-02-14 2017-12-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 196,585 1,611 0.83 724 -14.22 0.0002
2017-11-13 2017-09-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 194,974 -27,718 -12.45 844 133.80 0.0002
2017-08-11 2017-06-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 222,692 -667,285 -74.98 361 -78.07 0.0001
2017-05-12 2017-03-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 889,977 67,716 8.24 1,646 29.20 0.0005
2017-02-13 2016-12-31 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 822,261 127,685 18.38 1,274 -75.04 0.0004
2016-11-09 2016-09-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 694,576 9,391 1.37 5,104 40.03 0.0016
2016-08-12 2016-06-30 13F ARROWHEAD PHARMACEUTICALS IN COM 04280A100 685,185 685,185 3,645 0.0012
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.