AnaptysBio, Inc.
MX ˙ BMV ˙ US0327241065
SecurityMX:ANAB / AnaptysBio, Inc.
InstitutionMorgan Stanley
Latest Disclosed Ownership1,006,063 shares
Ownership 3.60%
Morgan Stanley ownership in ANAB / AnaptysBio, Inc.

2026-02-11 - Morgan Stanley has filed an SCHEDULE 13G/A form with the Securities and Exchange Commission (SEC) disclosing ownership of 1,006,063 shares of AnaptysBio, Inc. (MX:ANAB). This represents 3.6 percent ownership of the company. In their previous filing dated 2025-08-05 , Morgan Stanley had reported owning 1,845,002 shares, indicating a decrease of -45.47 percent.

Institutional Ownership: 13D/G Filings

This table shows a history of the 13D/G filings made by the investor and/or investor group. Note that the share values in this table are not directly comparable to any numbers shown in the 13F table (if any).

File
Date		Effective
Date		Form Prev
Shares		 Latest
Shares		 ΔShares
(Percent)		 Ownership
(Percent)		 ΔOwnership
(Percent)
2026-02-11 2026-02-11 13G/A 1,845,002 1,006,063 -45.47 3.60 -42.86
2025-08-05 2025-08-05 13G 1,845,002 6.30

Important Note: One of the primary uses of the 13D/G filings is to evaluate the ability of a firm to control a company (ie, the "beneficial ownership"). To that end, firms are required to report not just direct holdings in companies, but indirect holdings that they control. For investment firms, these indirect holdings can include shares in funds they manage, advisory accounts, and in the case of activist campaigns, pledged votes. Therefore, share counts listed in 13D/G filings can differ significantly than share counts listed in 13F filings.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F ANAPTYSBIO COM 032724106 993,905 -40,657 -3.93 55,122 9.90 0.0033
2026-05-27 2025-12-31 13F/A-1 ANAPTYSBIO COM 032724106 1,034,562 -521,696 -33.52 50,156 5.25 0.0030
2026-02-13 2025-12-31 13F ANAPTYSBIO COM 032724106 1,034,562 -521,696 50,156 0.0030
2026-05-27 2025-09-30 13F/A-1 ANAPTYSBIO COM 032724106 1,556,258 -313,582 -16.77 47,653 14.80 0.0029
2025-11-14 2025-09-30 13F ANAPTYSBIO COM 032724106 1,556,258 -313,582 47,653 0.0029
2025-08-15 2025-06-30 13F ANAPTYSBIO COM 032724106 1,869,840 1,365,204 270.53 41,510 342.49 0.0027
2025-05-15 2025-03-31 13F ANAPTYSBIO COM 032724106 504,636 288,719 133.72 9,381 228.24 0.0007
2025-05-15 2024-12-31 13F/A-1 ANAPTYSBIO COM 032724106 215,917 38,535 21.72 2,859 -51.90 0.0002
2025-02-14 2024-12-31 13F ANAPTYSBIO COM 032724106 215,917 38,535 2,859 0.0002
2025-05-14 2024-09-30 13F/A-2 ANAPTYSBIO COM 032724106 177,382 85,614 93.29 5,942 158.46 0.0004
2025-02-14 2024-09-30 13F/A-1 ANAPTYSBIO COM 032724106 177,382 85,614 5,942 0.0004
2024-11-14 2024-09-30 13F ANAPTYSBIO COM 032724106 177,382 85,614 5,942 0.0004
2025-05-14 2024-06-30 13F/A-2 ANAPTYSBIO COM 032724106 91,768 -544,346 -85.57 2,300 -83.95 0.0002
2024-10-17 2024-06-30 13F/A-1 ANAPTYSBIO COM 032724106 91,768 -544,346 2,300 0.0002
2024-08-14 2024-06-30 13F ANAPTYSBIO COM 032724106 91,768 -544,346 2,300 0.0002
2024-10-17 2024-03-31 13F/A-2 ANAPTYSBIO COM 032724106 636,114 34,082 5.66 14,325 11.09 0.0011
2024-08-16 2024-03-31 13F/A-1 ANAPTYSBIO COM 032724106 636,114 34,082 14,325 0.0001
2024-05-15 2024-03-31 13F ANAPTYSBIO COM 032724106 636,114 34,082 14,325 0.0011
2024-08-16 2023-12-31 13F/A-1 ANAPTYSBIO COM 032724106 602,032 521,045 643.37 12,896 786.86 0.0011
2024-02-13 2023-12-31 13F ANAPTYSBIO COM 032724106 602,032 521,045 12,896 0.0011
2023-11-15 2023-09-30 13F ANAPTYSBIO COM 032724106 80,987 9,369 13.08 1,455 -0.14 0.0001
2023-08-14 2023-06-30 13F ANAPTYSBIO COM 032724106 71,618 -27,012 -27.39 1,457 -32.15 0.0001
2023-05-15 2023-03-31 13F ANAPTYSBIO COM 032724106 98,630 2,714 2.83 2,146 -27.79 0.0002
2023-02-14 2022-12-31 13F ANAPTYSBIO COM 032724106 95,916 -11,652 -10.83 2,972 8.31 0.0003
2022-11-14 2022-09-30 13F ANAPTYSBIO COM 032724106 107,568 -39,087 -26.65 2,744 -7.80 0.0004
2022-10-27 2022-06-30 13F/A-1 ANAPTYSBIO COM 032724106 146,655 41,664 39.68 2,976 14.59 0.0004
2022-08-15 2022-06-30 13F ANAPTYSBIO COM 032724106 146,655 41,664 2,976 0.0004
2022-10-27 2022-03-31 13F/A-1 ANAPTYSBIO COM 032724106 104,991 32,264 44.36 2,597 2.77 0.0004
2022-05-13 2022-03-31 13F ANAPTYSBIO COM 032724106 104,991 32,264 2,597 0.0004
2022-02-14 2021-12-31 13F ANAPTYSBIO COM 032724106 72,727 781 1.09 2,527 29.52 0.0003
2021-11-15 2021-09-30 13F ANAPTYSBIO COM 032724106 71,946 -89,729 -55.50 1,951 -53.45 0.0003
2021-08-23 2021-06-30 13F/A-1 ANAPTYSBIO COM 032724106 161,675 2,136 1.34 4,191 21.90 0.0006
2021-08-16 2021-06-30 13F ANAPTYSBIO COM 032724106 161,675 2,136 4,191 0.0001
2021-05-17 2021-03-31 13F ANAPTYSBIO COM 032724106 159,539 137,996 640.56 3,438 642.55 0.0005
2021-02-16 2020-12-31 13F ANAPTYSBIO COM 032724106 21,543 14,093 189.17 463 324.77 0.0001
2020-11-13 2020-09-30 13F ANAPTYSBIO COM 032724106 7,450 -11,946 -61.59 109 -74.88 0.0000
2020-08-14 2020-06-30 13F ANAPTYSBIO COM 032724106 19,396 -484,698 -96.15 434 -93.91 0.0001
2020-05-26 2020-03-31 13F/A-1 ANAPTYSBIO COM 032724106 504,094 -544,171 -51.91 7,123 -58.18 0.0019
2020-05-15 2020-03-31 13F ANAPTYSBIO COM 032724106 504,094 -544,171 7,123 547.1949
2020-02-14 2019-12-31 13F ANAPTYSBIO COM 032724106 1,048,265 843,306 411.45 17,034 137.54 0.0040
2019-11-14 2019-09-30 13F ANAPTYSBIO COM 032724106 204,959 193,096 1,627.72 7,171 970.30 0.0019
2019-08-14 2019-06-30 13F ANAPTYSBIO COM 032724106 11,863 784 7.08 670 -17.18 0.0002
2019-05-15 2019-03-31 13F ANAPTYSBIO COM 032724106 11,079 -144,453 -92.88 809 -91.85 0.0002
2019-02-14 2018-12-31 13F ANAPTYSBIO COM 032724106 155,532 121,669 359.30 9,921 193.61 0.0030
2019-04-23 2018-09-30 13F/A-2 ANAPTYSBIO COM 032724106 33,863 -7,209 -17.55 3,379 15.84 0.0008
2018-11-20 2018-09-30 13F/A-1 ANAPTYSBIO COM 032724106 33,863 0 3,379 0.0008
2018-11-14 2018-09-30 13F ANAPTYSBIO COM 032724106 33,863 -7,209 3,379
2019-04-23 2018-06-30 13F/A-1 ANAPTYSBIO COM 032724106 41,072 3,523 9.38 2,917 -25.36 0.0008
2018-08-14 2018-06-30 13F ANAPTYSBIO COM 032724106 41,072 3,523 2,917
2019-04-23 2018-03-31 13F/A-1 ANAPTYSBIO COM 032724106 37,549 -285,845 -88.39 3,908 -88.00 0.0011
2018-05-14 2018-03-31 13F ANAPTYSBIO COM 032724106 37,549 -285,845 3,908
2019-04-23 2017-12-31 13F/A-1 ANAPTYSBIO COM 032724106 323,394 307,782 1,971.45 32,573 5,865.75 0.0089
2018-02-14 2017-12-31 13F ANAPTYSBIO COM 032724106 323,394 307,782 32,573
2017-11-14 2017-09-30 13F ANAPTYSBIO COM 032724106 15,612 10,548 208.29 546 351.24 0.0002
2017-08-11 2017-06-30 13F ANAPTYSBIO COM 032724106 5,064 -6,096 -54.62 121 -60.97 0.0000
2017-05-22 2017-03-31 13F/A-1 ANAPTYSBIO COM 032724106 11,160 11,160 310 0.0001
2017-05-12 2017-03-31 13F ANAPTYSBIO COM 032724106 11,160 310 0.0001
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.