Vertex Pharmaceuticals Incorporated
IT ˙ BIT ˙ US92532F1003
366,30 € ↓ -1,30 (-0,35%)
2026-06-03
DEL PRIS
SecurityIT:1VRTX / Vertex Pharmaceuticals Incorporated
InstitutionGAM Holding AG
Latest Disclosed Ownership9,552 shares
Latest Disclosed Value $ 4,330,495
GAM Holding AG reports 13.28% decrease in ownership of 1VRTX / Vertex Pharmaceuticals Incorporated

On February 17, 2026 - GAM Holding AG filed a 13F-HR form disclosing ownership of 9,552 shares of Vertex Pharmaceuticals Incorporated (IT:1VRTX) valued at $3,722,414 USD as of December 31, 2025. The entity filed a previous 13F-HR on October 21, 2025 disclosing 11,015 shares of Vertex Pharmaceuticals Incorporated. This represents a change in shares of -13.28% during the quarter. The current value of the position is $3,498,898 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-02-17 2025-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 9,552 -1,463 -13.28 4,330 0.39 0.2100
2025-10-21 2025-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 11,015 462 4.38 4,314 -8.19 0.1950
2025-08-04 2025-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 10,553 -492 -4.45 4,698 -12.25 0.3303
2025-04-22 2025-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 11,045 988 9.82 5,355 32.23 0.4153
2025-01-31 2024-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 10,057 -234 -2.27 4,050 -15.40 0.3020
2024-10-22 2024-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 10,291 1,381 15.50 4,786 14.61 0.3816
2024-07-26 2024-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 8,910 -1,406 -13.63 4,176 -3.15 0.3204
2024-05-13 2024-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 10,316 10 0.10 4,312 2.84 0.3120
2024-01-23 2023-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 10,306 2,979 40.66 4,193 64.63 0.3119
2023-10-16 2023-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 7,327 2 0.03 2,548 -1.16 0.1881
2023-07-27 2023-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 7,325 -12 -0.16 2,578 11.51 0.1779
2023-05-09 2023-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 7,337 428 6.19 2,312 15.84 0.1604
2023-02-02 2022-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,909 6,909 1,995 0.1602
2022-10-19 2022-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -6,160 -100.00 0 -100.00
2022-07-21 2022-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 6,160 0 0.00 1,736 7.96 0.1155
2022-05-06 2022-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,160 -1 -0.02 1,608 18.85 0.0690
2022-02-18 2021-12-31 13F/A-1 VERTEX PHARMACEUTICALS COM 92532F100 6,161 -1,074 -14.84 1,353 3.13 0.0603
2022-01-26 2021-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,161 -1,074 1,353 0.0606
2021-11-12 2021-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 7,235 1 0.01 1,312 -10.08 0.0610
2021-08-09 2021-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 7,234 -2,437 -25.20 1,459 -29.82 0.0632
2021-05-10 2021-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 9,671 9,671 2,079 0.0967
2021-02-10 2020-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -21,922 -100.00 0 -100.00
2020-11-06 2020-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 21,922 29 0.13 5,966 -6.12 0.3591
2020-08-10 2020-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 21,893 -381 -1.71 6,355 19.91 0.3950
2020-05-12 2020-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 22,274 -524 -2.30 5,300 6.17 0.3602
2020-02-06 2019-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 22,798 -35 -0.15 4,992 29.06 0.2358
2019-11-08 2019-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 22,833 -85 -0.37 3,868 -7.97 0.1703
2019-08-12 2019-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 22,918 96 0.42 4,203 0.12 0.1642
2019-05-10 2019-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 22,822 13,219 137.65 4,198 163.86 0.1764
2019-02-08 2018-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 9,603 -1,100 -10.28 1,591 -22.88 0.0805
2018-11-13 2018-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 10,703 4,103 62.17 2,063 83.87 0.0751
2018-08-09 2018-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 6,600 0 0.00 1,122 4.28 0.0390
2018-05-15 2018-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 6,600 -8,300 -55.70 1,076 -51.81 0.0380
2018-02-14 2017-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 14,900 14,900 2,233 0.0685
2017-11-14 2017-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 0 -23,537 -100.00 0 -100.00
2017-08-07 2017-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 23,537 -1,266 -5.10 3,033 11.84 0.0447
2017-05-12 2017-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 24,803 -369 -1.47 2,712 46.28 0.0428
2017-02-10 2016-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 25,172 972 4.02 1,854 -12.13 0.0325
2016-11-07 2016-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 24,200 0 0.00 2,110 1.34 0.0371
2016-08-11 2016-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 24,200 987 4.25 2,082 12.85 0.0323
2016-05-13 2016-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 23,213 -14,300 -38.12 1,845 -60.91 0.0307
2016-02-08 2015-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 37,513 15,092 67.31 4,720 102.14 0.0735
2015-11-12 2015-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 22,421 61 0.27 2,335 -15.43 0.0401
2015-07-27 2015-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 22,360 -15,227 -40.51 2,761 -37.73 0.0400
2015-05-12 2015-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 37,587 -7,017 -15.73 4,434 -16.34 0.0663
2015-02-06 2014-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 44,604 -57,071 -56.13 5,300 -53.59 0.0792
2014-11-12 2014-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 101,675 18,441 22.16 11,419 44.89 0.1659
2014-08-11 2014-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 83,234 5,784 7.47 7,881 43.89 0.1196
2014-05-15 2014-03-31 13F VERTEX PHARMACEUTICALS COM 92532F100 77,450 -14,263 -15.55 5,477 -19.62 0.0880
2014-02-12 2013-12-31 13F VERTEX PHARMACEUTICALS COM 92532F100 91,713 38,158 71.25 6,814 67.79 0.1188
2013-11-12 2013-09-30 13F VERTEX PHARMACEUTICALS COM 92532F100 53,555 11,860 28.44 4,061 21.81 0.0760
2013-08-13 2013-06-30 13F VERTEX PHARMACEUTICALS COM 92532F100 41,695 41,695 3,334 0.0729
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.