Cytokinetics, Incorporated
IT ˙ BIT ˙ US23282W6057
62,32 € 0,00 (0,00%)
2026-06-05
DEL PRIS
SecurityIT:1CYTK / Cytokinetics, Incorporated
InstitutionTwo Sigma Advisers, Lp
Latest Disclosed Ownership174,700 shares
Latest Disclosed Value $ 11,100,438
Two Sigma Advisers, Lp ownership in 1CYTK / Cytokinetics, Incorporated

On February 17, 2026 - Two Sigma Advisers, Lp filed a 13F-HR form disclosing ownership of 174,700 shares of Cytokinetics, Incorporated (IT:1CYTK) valued at $9,259,100 USD as of December 31, 2025. The entity filed a previous 13F-HR on August 14, 2025 disclosing 0 shares of Cytokinetics, Incorporated. The current value of the position is $10,887,304 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-02-17 2025-12-31 13F CYTOKINETICS COM NEW 23282W605 174,700 174,700 11,100 0.0216
2025-08-14 2025-06-30 13F CYTOKINETICS COM NEW 23282W605 0 -100.00 0
2025-05-15 2025-03-31 13F CYTOKINETICS COM NEW 23282W605 80,400 -146,000 -64.49 3,231 -69.66 0.0073
2025-02-14 2024-12-31 13F CYTOKINETICS COM NEW 23282W605 226,400 11,700 5.45 10,650 -6.06 0.0246
2024-11-14 2024-09-30 13F CYTOKINETICS COM NEW 23282W605 214,700 214,700 11,336 0.0266
2024-08-14 2024-06-30 13F CYTOKINETICS COM NEW 23282W605 0 -7,000 -100.00 0 -100.00
2024-05-15 2024-03-31 13F CYTOKINETICS COM NEW 23282W605 7,000 -76,800 -91.65 491 -93.00 0.0011
2024-02-14 2023-12-31 13F CYTOKINETICS COM NEW 23282W605 83,800 -93,100 -52.63 6,996 34.25 0.0164
2023-11-14 2023-09-30 13F CYTOKINETICS COM NEW 23282W605 176,900 -101,500 -36.46 5,211 -42.62 0.0133
2023-08-14 2023-06-30 13F CYTOKINETICS COM NEW 23282W605 278,400 -178,600 -39.08 9,081 -43.53 0.0231
2023-05-15 2023-03-31 13F CYTOKINETICS COM NEW 23282W605 457,000 2,000 0.44 16,082 -22.87 0.0415
2023-02-14 2022-12-31 13F CYTOKINETICS COM NEW 23282W605 455,000 53,100 13.21 20,848 7.07 0.0582
2022-11-14 2022-09-30 13F CYTOKINETICS COM NEW 23282W605 401,900 -62,500 -13.46 19,472 6.72 0.0564
2022-08-15 2022-06-30 13F CYTOKINETICS COM NEW 23282W605 464,400 -114,900 -19.83 18,246 -14.43 0.0518
2022-05-16 2022-03-31 13F CYTOKINETICS COM NEW 23282W605 579,300 -199,800 -25.64 21,324 -39.95 0.0567
2022-02-14 2021-12-31 13F CYTOKINETICS COM NEW 23282W605 779,100 -40,800 -4.98 35,511 21.19 0.0889
2021-11-15 2021-09-30 13F CYTOKINETICS COM NEW 23282W605 819,900 -57,100 -6.51 29,303 68.83 0.0760
2021-08-16 2021-06-30 13F CYTOKINETICS COM NEW 23282W605 877,000 -98,300 -10.08 17,356 -23.49 0.0458
2021-05-17 2021-03-31 13F CYTOKINETICS COM NEW 23282W605 975,300 221,200 29.33 22,685 44.77 0.0623
2021-02-16 2020-12-31 13F CYTOKINETICS COM NEW 23282W605 754,100 -43,400 -5.44 15,670 -9.24 0.0419
2020-11-16 2020-09-30 13F CYTOKINETICS COM NEW 23282W605 797,500 70,300 9.67 17,266 0.74 0.0493
2020-09-15 2020-06-30 13F/A-1 CYTOKINETICS COM NEW 23282W605 727,200 53,400 7.93 17,140 115.76 0.0504
2020-08-14 2020-06-30 13F CYTOKINETICS COM NEW 23282W605 727,200 53,400 17,140 49,528.9076
2020-05-15 2020-03-31 13F CYTOKINETICS COM NEW 23282W605 673,800 153,000 29.38 7,944 43.76 0.0304
2020-02-14 2019-12-31 13F CYTOKINETICS COM NEW 23282W605 520,800 250,000 92.32 5,526 79.30 0.0128
2019-11-14 2019-09-30 13F CYTOKINETICS COM NEW 23282W605 270,800 14,300 5.58 3,082 6.79 0.0075
2019-08-14 2019-06-30 13F CYTOKINETICS COM NEW 23282W605 256,500 24,100 10.37 2,886 53.51 0.0072
2019-05-15 2019-03-31 13F CYTOKINETICS COM NEW 23282W605 232,400 168,700 264.84 1,880 366.50 0.0047
2019-02-14 2018-12-31 13F CYTOKINETICS COM NEW 23282W605 63,700 -3,200 -4.78 403 -38.85 0.0011
2018-11-14 2018-09-30 13F CYTOKINETICS COM NEW 23282W605 66,900 -11,700 -14.89 659 1.07 0.0016
2018-08-14 2018-06-30 13F CYTOKINETICS COM NEW 23282W605 78,600 -5,400 -6.43 652 7.77 0.0018
2018-05-15 2018-03-31 13F CYTOKINETICS COM NEW 23282W605 84,000 9,200 12.30 605 -0.82 0.0016
2018-02-14 2017-12-31 13F CYTOKINETICS COM NEW 23282W605 74,800 28,800 62.61 610 -8.55 0.0016
2017-11-14 2017-09-30 13F CYTOKINETICS COM NEW 23282W605 46,000 8,300 22.02 667 46.27 0.0019
2017-08-14 2017-06-30 13F CYTOKINETICS COM NEW 23282W605 37,700 -2,800 -6.91 456 -12.31 0.0015
2017-05-15 2017-03-31 13F CYTOKINETICS COM NEW 23282W605 40,500 -8,900 -18.02 520 -13.33 0.0017
2017-02-14 2016-12-31 13F CYTOKINETICS COM NEW 23282W605 49,400 -40,300 -44.93 600 -27.10 0.0023
2016-11-14 2016-09-30 13F CYTOKINETICS COM NEW 23282W605 89,700 45,800 104.33 823 97.36 0.0035
2016-08-15 2016-06-30 13F CYTOKINETICS COM NEW 23282W605 43,900 -23,300 -34.67 417 -12.03 0.0021
2016-05-16 2016-03-31 13F CYTOKINETICS COM NEW 23282W605 67,200 -11,395 -14.50 474 -42.34 0.0027
2016-02-16 2015-12-31 13F CYTOKINETICS COM NEW 23282W605 78,595 66,493 549.44 822 914.81 0.0049
2015-11-16 2015-09-30 13F CYTOKINETICS COM NEW 23282W605 12,102 12,102 81 0.0005
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.