Ionis Pharmaceuticals, Inc.
GB ˙ LSE ˙ US4622221004
73,83 $ ↑0,93 (1,28%)
2026-06-03
DEL PRIS
SecurityGB:0JDI / Ionis Pharmaceuticals, Inc.
InstitutionBellevue Group AG
Latest Disclosed Ownership1,818,665 shares
Latest Disclosed Value $ 136,563,555
Bellevue Group AG reports 62.13% decrease in ownership of 0JDI / Ionis Pharmaceuticals, Inc.

On May 14, 2026 - Bellevue Group AG filed a 13F-HR form disclosing ownership of 1,818,665 shares of Ionis Pharmaceuticals, Inc. (GB:0JDI) valued at $136,759,971 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 4,802,199 shares of Ionis Pharmaceuticals, Inc.. This represents a change in shares of -62.13% during the quarter. The current value of the position is $134,272,037 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-14 2026-03-31 13F IONIS PHARMACEUTICALS COM 462222100 1,818,665 -2,983,534 -62.13 136,564 -64.05 3.2278
2026-02-17 2025-12-31 13F IONIS PHARMACEUTICALS COM 462222100 4,802,199 -1,442,252 -23.10 379,902 -7.00 7.1993
2025-11-14 2025-09-30 13F IONIS PHARMACEUTICALS COM 462222100 6,244,451 -1,608,747 -20.49 408,512 31.66 8.4880
2025-08-14 2025-06-30 13F IONIS PHARMACEUTICALS COM 462222100 7,853,198 0 0.00 310,280 30.96 6.8386
2025-05-14 2025-03-31 13F IONIS PHARMACEUTICALS COM 462222100 7,853,198 -15,502 -0.20 236,931 -13.87 5.3090
2025-02-14 2024-12-31 13F IONIS PHARMACEUTICALS COM 462222100 7,868,700 -5,700 -0.07 275,090 -12.79 5.2952
2024-11-14 2024-09-30 13F IONIS PHARMACEUTICALS COM 462222100 7,874,400 -386,034 -4.67 315,448 -19.87 5.1104
2024-08-14 2024-06-30 13F IONIS PHARMACEUTICALS COM 462222100 8,260,434 -39,080 -0.47 393,692 9.42 6.3970
2024-05-15 2024-03-31 13F IONIS PHARMACEUTICALS COM 462222100 8,299,514 -414,473 -4.76 359,784 -18.39 5.4871
2024-02-14 2023-12-31 13F IONIS PHARMACEUTICALS COM 462222100 8,713,987 -519,713 -5.63 440,841 5.25 6.7433
2023-11-14 2023-09-30 13F IONIS PHARMACEUTICALS COM 462222100 9,233,700 -146,600 -1.56 418,841 8.83 6.7480
2023-08-14 2023-06-30 13F IONIS PHARMACEUTICALS COM 462222100 9,380,300 -131,600 -1.38 384,874 13.21 5.4900
2023-05-15 2023-03-31 13F IONIS PHARMACEUTICALS COM 462222100 9,511,900 -232,000 -2.38 339,955 -7.63 4.9332
2023-02-14 2022-12-31 13F IONIS PHARMACEUTICALS COM 462222100 9,743,900 280,500 2.96 368,027 -12.07 4.8845
2022-11-14 2022-09-30 13F IONIS PHARMACEUTICALS COM 462222100 9,463,400 -313,128 -3.20 418,566 15.65 6.0073
2022-08-11 2022-06-30 13F IONIS PHARMACEUTICALS COM 462222100 9,776,528 -141,545 -1.43 361,927 -1.48 5.1162
2022-05-13 2022-03-31 13F IONIS PHARMACEUTICALS COM 462222100 9,918,073 -437,050 -4.22 367,365 16.58 4.2658
2022-02-10 2021-12-31 13F IONIS PHARMACEUTICALS COM 462222100 10,355,123 1,007,197 10.77 315,106 0.50 3.2480
2021-11-12 2021-09-30 13F IONIS PHARMACEUTICALS COM 462222100 9,347,926 -582,319 -5.86 313,529 -20.85 3.1818
2021-08-12 2021-06-30 13F IONIS PHARMACEUTICALS COM 462222100 9,930,245 946,011 10.53 396,117 -1.93 3.8667
2021-05-12 2021-03-31 13F IONIS PHARMACEUTICALS COM 462222100 8,984,234 -65,858 -0.73 403,932 -21.06 4.2737
2021-02-16 2020-12-31 13F IONIS PHARMACEUTICALS COM 462222100 9,050,092 333,822 3.83 511,693 23.72 5.8599
2020-11-16 2020-09-30 13F IONIS PHARMACEUTICALS COM 462222100 8,716,270 466,397 5.65 413,588 -14.97 5.7146
2020-08-13 2020-06-30 13F IONIS PHARMACEUTICALS COM 462222100 8,249,873 -129,769 -1.55 486,413 22.77 6.8839
2020-05-14 2020-03-31 13F IONIS PHARMACEUTICALS COM 462222100 8,379,642 -52,178 -0.62 396,189 -22.22 7.6832
2020-02-14 2019-12-31 13F IONIS PHARMACEUTICALS COM 462222100 8,431,820 109,906 1.32 509,366 2.17 8.0757
2019-11-14 2019-09-30 13F IONIS PHARMACEUTICALS COM 462222100 8,321,914 364,786 4.58 498,566 -2.51 9.2725
2019-08-14 2019-06-30 13F IONIS PHARMACEUTICALS COM 462222100 7,957,128 7,654,485 2,529.21 511,404 1,981.76 8.7319
2019-05-15 2019-03-31 13F IONIS PHARMACEUTICALS COM 462222100 302,643 -79,945 -20.90 24,566 18.77 1.3517
2019-02-12 2018-12-31 13F IONIS PHARMACEUTICALS COM 462222100 382,588 72,052 23.20 20,683 29.13 1.3599
2018-11-13 2018-09-30 13F IONIS PHARMACEUTICALS COM 462222100 310,536 -12,050 -3.74 16,017 19.16 1.0160
2018-08-07 2018-06-30 13F IONIS PHARMACEUTICALS COM 462222100 322,586 10,400 3.33 13,442 -2.32 1.1460
2018-05-09 2018-03-31 13F IONIS PHARMACEUTICALS COM 462222100 312,186 55,480 21.61 13,761 6.61 1.3633
2018-02-14 2017-12-31 13F IONIS PHARMACEUTICALS COM 462222100 256,706 -9,000 -3.39 12,908 -4.17 1.3485
2017-11-13 2017-09-30 13F IONIS PHARMACEUTICALS COM 462222100 265,706 41,144 18.32 13,469 17.91 1.4087
2017-08-14 2017-06-30 13F IONIS PHARMACEUTICALS COM 462222100 224,562 19,309 9.41 11,423 38.44 1.3507
2017-05-11 2017-03-31 13F IONIS PHARMACEUTICALS COM 462222100 205,253 114,253 125.55 8,251 89.55 1.0995
2017-02-10 2016-12-31 13F IONIS PHARMACEUTICALS COM 462222100 91,000 -17,000 -15.74 4,353 10.01 0.8914
2016-11-10 2016-09-30 13F Ionis Pharmaceuticals COM 462222100 108,000 0 0.00 3,957 57.34 0.7149
2016-08-12 2016-06-30 13F Ionis Pharmaceuticals COM 462222100 108,000 -30,000 -21.74 2,515 -55.00 0.4732
2016-05-16 2016-03-31 13F Ionis Pharmaceuticals COM 462222100 138,000 138,000 5,589 1.0142
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.