uniQure N.V.
GB ˙ LSE ˙ NL0010696654
26,59 $ ↓ -3,22 (-10,80%)
2026-06-05
DEL PRIS
SecurityGB:0EE0 / uniQure N.V.
InstitutionOrbimed Advisors Llc
ManagerSamuel Isaly
Latest Disclosed Ownership2,136,149 shares
Latest Disclosed Value $ 34,926,036
Orbimed Advisors Llc reports 189.69% increase in ownership of 0EE0 / uniQure N.V.

On May 15, 2026 - Orbimed Advisors Llc filed a 13F-HR form disclosing ownership of 2,136,149 shares of uniQure N.V. (GB:0EE0) valued at $33,594,147 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 737,400 shares of uniQure N.V.. This represents a change in shares of 189.69% during the quarter. The current value of the position is $56,800,202 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F UNIQURE SHS N90064101 2,136,149 1,398,749 189.69 34,926 97.94 0.6916
2026-02-17 2025-12-31 13F UNIQURE SHS N90064101 737,400 278,900 60.83 17,646 -34.07 0.3602
2025-11-14 2025-09-30 13F UNIQURE SHS N90064101 458,500 458,500 26,763 0.6289
2024-05-15 2024-03-31 13F UNIQURE SHS N90064101 0 -1,347,900 -100.00 0 -100.00
2024-02-14 2023-12-31 13F UNIQURE SHS N90064101 1,347,900 -716,555 -34.71 9,125 -34.13 0.1822
2023-11-14 2023-09-30 13F UNIQURE SHS N90064101 2,064,455 0 0.00 13,852 -41.45 0.2943
2023-08-14 2023-06-30 13F UNIQURE SHS N90064101 2,064,455 0 0.00 23,659 -43.10 0.4287
2023-05-15 2023-03-31 13F UNIQURE SHS N90064101 2,064,455 316,900 18.13 41,578 4.95 0.8162
2023-02-14 2022-12-31 13F UNIQURE SHS N90064101 1,747,555 150,555 9.43 39,617 32.23 0.7579
2022-11-14 2022-09-30 13F UNIQURE SHS N90064101 1,597,000 722,151 82.55 29,960 83.72 0.5562
2022-08-15 2022-06-30 13F UNIQURE SHS N90064101 874,849 -44,400 -4.83 16,307 -1.83 0.2955
2022-05-16 2022-03-31 13F UNIQURE SHS N90064101 919,249 333,675 56.98 16,611 36.77 0.2693
2022-02-14 2021-12-31 13F UNIQURE SHS N90064101 585,574 0 0.00 12,145 -35.21 0.1561
2021-11-15 2021-09-30 13F UNIQURE SHS N90064101 585,574 114,400 24.28 18,744 29.16 0.2060
2021-08-16 2021-06-30 13F UNIQURE SHS N90064101 471,174 -497,905 -51.38 14,512 -55.55 0.1468
2021-05-17 2021-03-31 13F UNIQURE SHS N90064101 969,079 0 0.00 32,648 -6.75 0.3053
2021-02-16 2020-12-31 13F UNIQURE SHS N90064101 969,079 0 0.00 35,013 -1.90 0.3064
2020-11-16 2020-09-30 13F UNIQURE SHS N90064101 969,079 0 0.00 35,691 -18.27 0.4486
2020-08-14 2020-06-30 13F UNIQURE SHS N90064101 969,079 -14,900 -1.51 43,667 -6.47 0.6148
2020-05-15 2020-03-31 13F UNIQURE SHS N90064101 983,979 -97,786 -9.04 46,690 -39.77 0.7847
2020-02-14 2019-12-31 13F UNIQURE SHS N90064101 1,081,765 242,165 28.84 77,519 134.57 1.1067
2019-11-14 2019-09-30 13F UNIQURE SHS N90064101 839,600 -58,200 -6.48 33,047 -52.90 0.6271
2019-08-14 2019-06-30 13F UNIQURE SHS N90064101 897,800 897,800 70,163 1.0866
2017-02-14 2016-12-31 13F UNIQURE SHS N90064101 0 -489,000 -100.00 0 -100.00
2016-11-14 2016-09-30 13F UNIQURE SHS N90064101 489,000 293,600 150.26 3,741 159.79 0.0426
2016-08-15 2016-06-30 13F UNIQURE SHS N90064101 195,400 10,600 5.74 1,440 -34.40 0.0150
2016-05-16 2016-03-31 13F UNIQURE SHS N90064101 184,800 184,800 2,195 0.0231
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.