Madrigal Pharmaceuticals, Inc.
DE ˙ DB ˙ US5588681057
426,20 € ↑6,40 (1,52%)
2026-06-04
DEL PRIS
SecurityDE:YDO1 / Madrigal Pharmaceuticals, Inc.
InstitutionProfund Advisors Llc
Latest Disclosed Ownership4,862 shares
Latest Disclosed Value $ 2,545,111
Profund Advisors Llc reports 16.96% increase in ownership of YDO1 / Madrigal Pharmaceuticals, Inc.

On April 24, 2026 - Profund Advisors Llc filed a 13F-HR form disclosing ownership of 4,862 shares of Madrigal Pharmaceuticals, Inc. (DE:YDO1) valued at $2,189,359 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 6, 2026 disclosing 4,157 shares of Madrigal Pharmaceuticals, Inc.. This represents a change in shares of 16.96% during the quarter. The current value of the position is $2,072,184 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-04-24 2026-03-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 4,862 705 16.96 2,545 5.17 0.0934
2026-02-06 2025-12-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 4,157 -45 -1.07 2,421 25.58 0.0736
2025-11-06 2025-09-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 4,202 -988 -19.04 1,927 22.74 0.0626
2025-08-07 2025-06-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 5,190 -1,063 -17.00 1,571 -24.19 0.0565
2025-05-08 2025-03-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 6,253 -231 -3.56 2,071 3.55 0.0900
2025-02-14 2024-12-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 6,484 -2,323 -26.38 2,001 7.01 0.0730
2024-11-14 2024-09-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 8,807 1,991 29.21 1,869 -2.10 0.0707
2024-08-13 2024-06-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 6,816 1,053 18.27 1,910 24.12 0.0708
2024-05-08 2024-03-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 5,763 -1,397 -19.51 1,539 -7.13 0.0599
2024-02-14 2023-12-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 7,160 -563 -7.29 1,657 46.94 0.0712
2023-11-13 2023-09-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 7,723 1,898 32.58 1,128 -16.21 0.0624
2023-08-10 2023-06-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 5,825 459 8.55 1,346 3.54 0.0722
2023-05-12 2023-03-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 5,366 4,233 373.61 1,300 296.04 0.0803
2023-02-02 2022-12-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 1,133 1,133 329 0.0213
2019-05-15 2019-03-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 0 -1,829 -100.00 0 -100.00
2019-02-14 2018-12-31 13F MADRIGAL PHARMACEUTICALS COM 558868105 1,829 67 3.80 206 -45.36 0.0127
2018-11-13 2018-09-30 13F MADRIGAL PHARMACEUTICALS COM 558868105 1,762 1,762 377 0.0143
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.