Northern Trust Corp reports 1.70% decrease in ownership of YDO1 / Madrigal Pharmaceuticals, Inc.

Madrigal Pharmaceuticals, Inc.

DE ˙ DB ˙ US5588681057

426,20 € ↑6,40 (1,52%)

2026-06-04
DEL PRIS

Security	DE:YDO1 / Madrigal Pharmaceuticals, Inc.
Institution	Northern Trust Corp
Latest Disclosed Ownership	149,214 shares
Latest Disclosed Value	$ 78,109,054

On May 14, 2026 - Northern Trust Corp filed a 13F-HR form disclosing ownership of 149,214 shares of Madrigal Pharmaceuticals, Inc. (DE:YDO1) valued at $67,191,064 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 151,802 shares of Madrigal Pharmaceuticals, Inc.. This represents a change in shares of -1.70% during the quarter. The current value of the position is $63,595,007 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)

File Date	Effective Date	Form	Security	Class	ID	Reported Shares	ΔShares	ΔShares (%)	Reported Value (x1000)	ΔValue (%)	Alloc (%)
2026-05-14	2026-03-31	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	149,214	-2,588	-1.70	78,109	-11.64	0.0021
2026-02-17	2025-12-31	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	151,802	-8,186	-5.12	88,400	20.47	0.0113
2025-11-14	2025-09-30	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	159,988	17,120	11.98	73,380	69.72	0.0094
2025-08-13	2025-06-30	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	142,868	-8,018	-5.31	43,238	-13.49	0.0059
2025-05-13	2025-03-31	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	150,886	-4,997	-3.21	49,978	3.90	0.0074
2025-02-14	2024-12-31	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	155,883	8,111	5.49	48,101	53.38	0.0068
2024-11-13	2024-09-30	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	147,772	16,327	12.42	31,360	-14.84	0.0051
2024-08-14	2024-06-30	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	131,445	87	0.07	36,826	4.98	0.0062
2024-05-14	2024-03-31	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	131,358	-3,348	-2.49	35,078	12.54	0.0061
2024-02-13	2023-12-31	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	134,706	11,057	8.94	31,168	72.61	0.0056
2023-11-13	2023-09-30	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	123,649	1,050	0.86	18,058	-36.24	0.0035
2023-08-11	2023-06-30	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	122,599	9,114	8.03	28,320	3.01	0.0054
2023-05-15	2023-03-31	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	113,485	1,992	1.79	27,493	-15.04	0.0055
2023-02-13	2022-12-31	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	111,493	-1,912	-1.69	32,361	339.08	0.0068
2022-11-14	2022-09-30	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	113,405	-1,590	-1.38	7,370	-10.46	0.0017
2022-08-12	2022-06-30	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	114,995	3,593	3.23	8,231	-24.69	0.0018
2022-05-13	2022-03-31	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	111,402	-5,528	-4.73	10,930	10.31	0.0019
2022-02-08	2021-12-31	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	116,930	4,883	4.36	9,908	10.84	0.0016
2021-11-15	2021-09-30	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	112,047	-2,815	-2.45	8,939	-20.10	0.0016
2021-08-13	2021-06-30	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	114,862	14,284	14.20	11,188	-4.90	0.0020
2021-05-12	2021-03-31	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	100,578	-3,445	-3.31	11,765	1.75	0.0022
2021-02-11	2020-12-31	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	104,023	-1,857	-1.75	11,563	-8.02	0.0023
2020-11-16	2020-09-30	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	105,880	-7,228	-6.39	12,571	-1.86	0.0028
2020-08-14	2020-06-30	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	113,108	1,932	1.74	12,809	72.58	0.0030
2020-05-14	2020-03-31	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	111,176	15,451	16.14	7,422	-14.90	0.0021
2020-02-14	2019-12-31	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	95,725	-8,962	-8.56	8,722	-3.38	0.0020
2019-11-13	2019-09-30	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	104,687	6,280	6.38	9,027	-12.48	0.0022
2019-08-13	2019-06-30	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	98,407	2,136	2.22	10,314	-14.47	0.0024
2019-05-13	2019-03-31	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	96,271	1,247	1.31	12,059	12.59	0.0030
2019-02-12	2018-12-31	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	95,024	-7,804	-7.59	10,711	-51.36	0.0030
2018-11-14	2018-09-30	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	102,828	12,165	13.42	22,019	-13.17	0.0054
2018-09-18	2018-06-30	13F/A-1	MADRIGAL PHARMACEUTICALS	COM	558868105	90,663	17,023	23.12	25,358	194.86	0.0064
2018-08-14	2018-06-30	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	91,483	17,843		25,587
2018-05-09	2018-03-31	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	73,640	8,393	12.86	8,600	43.60	0.0022
2018-02-14	2017-12-31	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	65,247	12,451	23.58	5,989	152.27	0.0015
2017-11-13	2017-09-30	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	52,796	2,727	5.45	2,374	191.65	0.0006
2017-08-11	2017-06-30	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	50,069	30,134	151.16	814	166.01	0.0002
2017-05-12	2017-03-31	13F	MADRIGAL PHARMACEUTICALS	COM	558868105	19,935	19,935		306		0.0001

Legend

Shares: The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value: The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price: The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class: This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred

Allocation (%): The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation: The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%): The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis: The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss: This is the market value of the position as of the effective date minus the cost basis.