OPKO Health, Inc.
DE ˙ DB ˙ US68375N1037
1,20 € ↑0,03 (2,56%)
2026-06-05
DEL PRIS
SecurityDE:XCY / OPKO Health, Inc.
InstitutionHsbc Holdings Plc
Latest Disclosed Ownership238,281 shares
Latest Disclosed Value $ 272,832
Hsbc Holdings Plc ownership in XCY / OPKO Health, Inc.

On April 30, 2026 - Hsbc Holdings Plc filed a 13F-HR form disclosing ownership of 238,281 shares of OPKO Health, Inc. (DE:XCY) valued at $223,150 USD as of March 31, 2026. The entity filed a previous 13F-HR on November 13, 2025 disclosing 0 shares of OPKO Health, Inc.. The current value of the position is $285,937 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

Upgrade to unlock premium data and export to Excel .

Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-04-30 2026-03-31 13F OPKO HEALTH COM 68375N103 238,281 238,281 273 0.0000
2025-11-13 2025-09-30 13F OPKO HEALTH COM 68375N103 0 -100.00 0
2025-08-13 2025-06-30 13F OPKO HEALTH COM 68375N103 34,939 -1,913 -5.19 46 -23.33 0.0000
2025-05-14 2025-03-31 13F OPKO HEALTH COM 68375N103 36,852 -1,034 -2.73 61 9.09 0.0000
2025-02-14 2024-12-31 13F OPKO HEALTH COM 68375N103 37,886 -3,423 -8.29 56 -9.84 0.0000
2024-11-14 2024-09-30 13F OPKO HEALTH COM 68375N103 41,309 -4,264 -9.36 62 8.93 0.0000
2024-08-12 2024-06-30 13F OPKO HEALTH COM 68375N103 45,573 -28,560 -38.53 57 -36.36 0.0000
2024-05-15 2024-03-31 13F OPKO HEALTH COM 68375N103 74,133 44,878 153.40 89 100.00 0.0001
2024-02-12 2023-12-31 13F OPKO HEALTH COM 68375N103 29,255 29,255 44 0.0000
2023-08-11 2023-06-30 13F OPKO HEALTH COM 68375N103 0 -31,531 -100.00 0 -100.00
2023-05-15 2023-03-31 13F OPKO HEALTH COM 68375N103 31,531 2,449 8.42 46 27.78 0.0001
2023-02-14 2022-12-31 13F OPKO HEALTH COM 68375N103 29,082 29,082 36 0.0000
2022-11-14 2022-09-30 13F OPKO HEALTH COM 68375N103 0 -38,129 -100.00 0 -100.00
2022-08-11 2022-06-30 13F OPKO HEALTH COM 68375N103 38,129 -12,910 -25.29 96 -45.45 0.0001
2022-05-16 2022-03-31 13F OPKO HEALTH COM 68375N103 51,039 -7,695 -13.10 176 -38.46 0.0002
2022-02-11 2021-12-31 13F OPKO HEALTH COM 68375N103 58,734 3,312 5.98 286 40.20 0.0003
2021-11-12 2021-09-30 13F OPKO HEALTH COM 68375N103 55,422 -12,922 -18.91 204 -26.09 0.0002
2021-08-13 2021-06-30 13F OPKO HEALTH COM 68375N103 68,344 37,222 119.60 276 104.44 0.0003
2021-05-14 2021-03-31 13F OPKO HEALTH COM 68375N103 31,122 -56,639 -64.54 135 -61.10 0.0002
2021-02-25 2020-12-31 13F/A-1 OPKO HEALTH COM 68375N103 87,761 1,042 1.20 347 8.78 0.0005
2021-02-12 2020-12-31 13F OPKO HEALTH COM 68375N103 87,761 1,042 347 82.3906
2020-11-12 2020-09-30 13F OPKO HEALTH COM 68375N103 86,719 -81,769 -48.53 319 -44.43 0.0005
2020-08-14 2020-06-30 13F OPKO HEALTH COM 68375N103 168,488 -19,625 -10.43 574 131.45 0.0011
2020-05-15 2020-03-31 13F OPKO HEALTH COM 68375N103 188,113 -137,951 -42.31 248 -48.76 0.0006
2020-02-14 2019-12-31 13F OPKO HEALTH COM 68375N103 326,064 101,754 45.36 484 3.20 0.0008
2019-11-14 2019-09-30 13F OPKO HEALTH COM 68375N103 224,310 119,337 113.68 469 83.20 0.0009
2019-08-13 2019-06-30 13F OPKO HEALTH COM 68375N103 104,973 32,404 44.65 256 35.45 0.0005
2019-05-15 2019-03-31 13F OPKO HEALTH COM 68375N103 72,569 15,103 26.28 189 9.25 0.0003
2019-02-13 2018-12-31 13F OPKO HEALTH COM 68375N103 57,466 25,269 78.48 173 55.86 0.0003
2018-11-13 2018-09-30 13F OPKO HEALTH COM 68375N103 32,197 112 0.35 111 -26.00 0.0002
2018-08-10 2018-06-30 13F OPKO HEALTH COM 68375N103 32,085 335 1.06 150 48.51 0.0003
2018-05-11 2018-03-31 13F OPKO HEALTH COM 68375N103 31,750 4,464 16.36 101 -24.63 0.0002
2018-02-14 2017-12-31 13F OPKO HEALTH COM 68375N103 27,286 9,257 51.35 134 8.06 0.0002
2017-11-14 2017-09-30 13F OPKO HEALTH COM 68375N103 18,029 0 0.00 124 4.20 0.0002
2017-08-14 2017-06-30 13F OPKO HEALTH COM 68375N103 18,029 18,029 0.00 119 -4.03 0.0002
2017-05-15 2017-03-31 13F OPKO HEALTH COM 68375N103 0 -174,502 -100.00 0 -100.00
2017-02-09 2016-12-31 13F OPKO HEALTH COM 68375N103 174,502 162,845 1,396.97 1,623 1,208.87 0.0038
2016-11-14 2016-09-30 13F OPKO HEALTH COM 68375N103 11,657 -3,585 -23.52 124 -12.06 0.0003
2016-08-12 2016-06-30 13F OPKO HEALTH COM 68375N103 15,242 15,242 141 0.0004
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.