OPKO Health, Inc.
DE ˙ DB ˙ US68375N1037
1,20 € ↑0,03 (2,56%)
2026-06-05
DEL PRIS
SecurityDE:XCY / OPKO Health, Inc.
InstitutionGeode Capital Management, Llc
Latest Disclosed Ownership11,301,501 shares
Latest Disclosed Value $ 12,886,259
Geode Capital Management, Llc reports 2.17% increase in ownership of XCY / OPKO Health, Inc.

On May 15, 2026 - Geode Capital Management, Llc filed a 13F-HR form disclosing ownership of 11,301,501 shares of OPKO Health, Inc. (DE:XCY) valued at $10,583,856 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 9, 2026 disclosing 11,061,318 shares of OPKO Health, Inc.. This represents a change in shares of 2.17% during the quarter. The current value of the position is $13,561,801 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F OPKO HEALTH COM 68375N103 11,301,501 240,183 2.17 12,886 -7.55 0.0004
2026-02-09 2025-12-31 13F OPKO HEALTH COM 68375N103 11,061,318 67,973 0.62 13,940 -18.21 0.0009
2025-11-12 2025-09-30 13F OPKO HEALTH COM 68375N103 10,993,345 568,872 5.46 17,043 23.84 0.0011
2025-08-08 2025-06-30 13F OPKO HEALTH COM 68375N103 10,424,473 1,995,633 23.68 13,763 -1.66 0.0010
2025-05-13 2025-03-31 13F OPKO HEALTH COM 68375N103 8,428,840 43,622 0.52 13,995 13.51 0.0011
2025-02-12 2024-12-31 13F OPKO HEALTH COM 68375N103 8,385,218 10,473 0.13 12,329 -1.21 0.0010
2024-11-12 2024-09-30 13F OPKO HEALTH COM 68375N103 8,374,745 -450,186 -5.10 12,481 13.12 0.0010
2024-08-09 2024-06-30 13F OPKO HEALTH COM 68375N103 8,824,931 -1,146,623 -11.50 11,033 -7.80 0.0010
2024-05-13 2024-03-31 13F OPKO HEALTH COM 68375N103 9,971,554 252,186 2.59 11,967 -18.46 0.0011
2024-02-13 2023-12-31 13F OPKO HEALTH COM 68375N103 9,719,368 589,076 6.45 14,678 0.46 0.0015
2023-11-13 2023-09-30 13F OPKO HEALTH COM 68375N103 9,130,292 387,678 4.43 14,610 -22.99 0.0017
2023-08-11 2023-06-30 13F OPKO HEALTH COM 68375N103 8,742,614 331,968 3.95 18,971 54.50 0.0022
2023-05-15 2023-03-31 13F OPKO HEALTH COM 68375N103 8,410,646 423,280 5.30 12,280 136,333.33 0.0016
2023-02-13 2022-12-31 13F OPKO HEALTH COM 68375N103 7,987,366 158,178 2.02 10 -99.94 0.0014
2022-11-14 2022-09-30 13F OPKO HEALTH COM 68375N103 7,829,188 200,456 2.63 14,797 -23.33 0.0022
2022-08-12 2022-06-30 13F OPKO HEALTH COM 68375N103 7,628,732 -138,759 -1.79 19,300 -27.77 0.0028
2022-05-13 2022-03-31 13F OPKO HEALTH COM 68375N103 7,767,491 37,079 0.48 26,720 -28.14 0.0033
2022-02-11 2021-12-31 13F OPKO HEALTH COM 68375N103 7,730,412 1,682 0.02 37,183 31.81 0.0045
2021-11-12 2021-09-30 13F OPKO HEALTH COM 68375N103 7,728,730 -53,188 -0.68 28,209 -10.49 0.0038
2021-08-13 2021-06-30 13F OPKO HEALTH COM 68375N103 7,781,918 255,210 3.39 31,516 -2.39 0.0043
2021-05-12 2021-03-31 13F OPKO HEALTH COM 68375N103 7,526,708 636,198 9.23 32,289 18.64 0.0049
2021-02-12 2020-12-31 13F OPKO HEALTH COM 68375N103 6,890,510 256,802 3.87 27,217 11.19 0.0046
2020-11-13 2020-09-30 13F OPKO HEALTH COM 68375N103 6,633,708 -44,297 -0.66 24,478 7.50 0.0048
2020-08-13 2020-06-30 13F OPKO HEALTH COM 68375N103 6,678,005 230,731 3.58 22,771 163.58 0.0049
2020-05-14 2020-03-31 13F OPKO HEALTH COM 68375N103 6,447,274 473,605 7.93 8,639 -1.62 0.0023
2020-02-20 2019-12-31 13F/A-1 OPKO HEALTH COM 68375N103 5,973,669 746,610 14.28 8,781 -19.62 0.0018
2020-02-13 2019-12-31 13F OPKO HEALTH COM 68375N103 5,973,669 746,610 8,781 1,119.0615
2019-11-12 2019-09-30 13F OPKO HEALTH COM 68375N103 5,227,059 54,866 1.06 10,924 -13.44 0.0025
2019-08-14 2019-06-30 13F OPKO HEALTH COM 68375N103 5,172,193 644,561 14.24 12,620 6.80 0.0031
2019-05-14 2019-03-31 13F OPKO HEALTH COM 68375N103 4,527,632 449,235 11.01 11,817 -3.73 0.0031
2019-03-06 2018-12-31 13F/A-1 OPKO HEALTH COM 68375N103 4,078,397 165,517 4.23 12,275 -9.32 0.0038
2019-02-13 2018-12-31 13F OPKO HEALTH COM 68375N103 4,078,397 165,517 12,275
2018-11-13 2018-09-30 13F OPKO HEALTH COM 68375N103 3,912,880 169,225 4.52 13,537 -23.06 0.0038
2018-08-14 2018-06-30 13F OPKO HEALTH COM 68375N103 3,743,655 237,893 6.79 17,595 58.34 0.0054
2018-05-15 2018-03-31 13F OPKO HEALTH COM 68375N103 3,505,762 76,491 2.23 11,112 -33.87 0.0036
2018-02-13 2017-12-31 13F OPKO HEALTH COM 68375N103 3,429,271 78,477 2.34 16,803 -26.90 0.0057
2017-11-14 2017-09-30 13F OPKO HEALTH COM 68375N103 3,350,794 190,931 6.04 22,986 10.56 0.0085
2017-08-14 2017-06-30 13F OPKO HEALTH COM 68375N103 3,159,863 270,804 9.37 20,791 -10.04 0.0082
2017-06-21 2017-03-31 13F/A-1 OPKO HEALTH COM 68375N103 2,889,059 210,736 7.87 23,111 -7.21 0.0095
2017-05-12 2017-03-31 13F OPKO HEALTH COM 68375N103 2,889,059 23,111
2017-02-14 2016-12-31 13F OPKO HEALTH COM 68375N103 2,678,323 294,354 12.35 24,908 -1.34 0.0116
2016-11-10 2016-09-30 13F OPKO HEALTH COM 68375N103 2,383,969 197,865 9.05 25,246 23.65 0.0127
2016-08-12 2016-06-30 13F OPKO HEALTH COM 68375N103 2,186,104 262,649 13.66 20,418 2.17 0.0111
2016-05-13 2016-03-31 13F OPKO HEALTH COM 68375N103 1,923,455 118,512 6.57 19,984 10.17 0.0106
2016-02-12 2015-12-31 13F OPKO HEALTH COM 68375N103 1,804,943 -33,670 -1.83 18,139 17.31 0.0103
2015-11-13 2015-09-30 13F OPKO HEALTH COM 68375N103 1,838,613 459,469 33.32 15,462 -30.28 0.0094
2015-08-14 2015-06-30 13F OPKO HEALTH COM 68375N103 1,379,144 9,903 0.72 22,176 14.30 0.0127
2015-05-14 2015-03-31 13F OPKO HEALTH COM 68375N103 1,369,241 106,228 8.41 19,401 53.77 0.0111
2015-02-12 2014-12-31 13F OPKO HEALTH COM 68375N103 1,263,013 62,703 5.22 12,617 23.53 0.0075
2014-11-14 2014-09-30 13F OPKO HEALTH COM 68375N103 1,200,310 2,773 0.23 10,214 -3.51 0.0066
2014-08-13 2014-06-30 13F OPKO HEALTH COM 68375N103 1,197,537 48,347 4.21 10,586 -1.16 0.0068
2014-05-14 2014-03-31 13F OPKO HEALTH COM 68375N103 1,149,190 89,780 8.47 10,710 19.79 0.0072
2014-02-14 2013-12-31 13F OPKO HEALTH COM 68375N103 1,059,410 113,828 12.04 8,941 7.32 0.0062
2013-11-14 2013-09-30 13F OPKO HEALTH COM 68375N103 945,582 325,429 52.48 8,331 89.21 0.0067
2013-08-14 2013-06-30 13F OPKO HEALTH COM 68375N103 620,153 620,153 4,403 0.0039
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.