OPKO Health, Inc.
DE ˙ DB ˙ US68375N1037
1,18 € ↑0,12 (11,32%)
2026-05-28
DEL PRIS
SecurityDE:XCY / OPKO Health, Inc.
InstitutionFmr Llc
Latest Disclosed Ownership41,343 shares
Latest Disclosed Value $ 47,131
Fmr Llc reports 193.48% increase in ownership of XCY / OPKO Health, Inc.

On May 15, 2026 - Fmr Llc filed a 13F-HR form disclosing ownership of 41,343 shares of OPKO Health, Inc. (DE:XCY) valued at $38,718 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 14,087 shares of OPKO Health, Inc.. This represents a change in shares of 193.48% during the quarter. The current value of the position is $48,785 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F OPKO HEALTH COM 68375N103 41,343 27,256 193.48 47 176.47 0.0000
2026-02-17 2025-12-31 13F OPKO HEALTH COM 68375N103 14,087 -2,477 -14.95 18 -32.00 0.0000
2025-11-13 2025-09-30 13F OPKO HEALTH COM 68375N103 16,564 443 2.75 26 19.05 0.0000
2025-08-14 2025-06-30 13F OPKO HEALTH COM 68375N103 16,121 -8,267 -33.90 21 -47.50 0.0000
2025-05-12 2025-03-31 13F OPKO HEALTH COM 68375N103 24,388 92 0.38 40 14.29 0.0000
2025-02-13 2024-12-31 13F OPKO HEALTH COM 68375N103 24,296 2,501 11.48 36 9.38 0.0000
2024-11-13 2024-09-30 13F OPKO HEALTH COM 68375N103 21,795 11,089 103.58 32 146.15 0.0000
2024-08-13 2024-06-30 13F OPKO HEALTH COM 68375N103 10,706 5,844 120.20 13 160.00 0.0000
2024-05-13 2024-03-31 13F OPKO HEALTH COM 68375N103 4,862 -7,175 -59.61 6 -72.22 0.0000
2024-02-13 2023-12-31 13F OPKO HEALTH COM 68375N103 12,037 1,226 11.34 18 5.88 0.0000
2023-11-13 2023-09-30 13F OPKO HEALTH COM 68375N103 10,811 -297 -2.67 17 -29.17 0.0000
2023-08-11 2023-06-30 13F OPKO HEALTH COM 68375N103 11,108 1,445 14.95 24 71.43 0.0000
2023-08-11 2023-03-31 13F/A-1 OPKO HEALTH COM 68375N103 9,663 1,981 25.79 14 55.56 0.0000
2023-05-11 2023-03-31 13F OPKO HEALTH COM 68375N103 9,663 1,981 14 0.0000
2023-02-13 2022-12-31 13F OPKO HEALTH COM 68375N103 7,682 948 14.08 10 -30.77 0.0000
2022-11-10 2022-09-30 13F OPKO HEALTH COM 68375N103 6,734 1,859 38.13 13 8.33 0.0000
2022-08-12 2022-06-30 13F OPKO HEALTH COM 68375N103 4,875 -292,725 -98.36 12 -98.83 0.0000
2022-05-13 2022-03-31 13F OPKO HEALTH COM 68375N103 297,600 297,599 29,759,900.00 1,024 0.0001
2022-02-14 2021-12-31 13F OPKO HEALTH COM 68375N103 1 1 0 0.0000
2022-02-14 2021-09-30 13F/A-1 OPKO HEALTH COM 68375N103 0 -1,013,011 -100.00 0 -100.00
2021-11-15 2021-09-30 13F OPKO HEALTH COM 68375N103 0 -1,013,011 0
2021-08-13 2021-06-30 13F OPKO HEALTH COM 68375N103 1,013,011 -306,000 -23.20 4,103 -27.50 0.0003
2021-05-14 2021-03-31 13F OPKO HEALTH COM 68375N103 1,319,011 1,319,011 5,659 0.0005
2020-11-13 2020-09-30 13F OPKO HEALTH COM 68375N103 0 -17 -100.00 0 0.0000
2020-08-24 2020-06-30 13F/A-1 OPKO HEALTH COM 68375N103 17 17 0 0.0000
2020-08-13 2020-06-30 13F OPKO HEALTH COM 68375N103 17 17 0 0.0000
2019-11-13 2019-09-30 13F OPKO HEALTH COM 68375N103 0 -2 -100.00 0 0.0000
2019-08-13 2019-06-30 13F OPKO HEALTH COM 68375N103 2 0 0.00 0 0.0000
2019-05-13 2019-03-31 13F OPKO HEALTH COM 68375N103 2 0 0.00 0 0.0000
2019-02-13 2018-12-31 13F OPKO HEALTH COM 68375N103 2 -682,700 -100.00 0 -100.00
2018-11-09 2018-09-30 13F OPKO HEALTH COM 68375N103 682,702 682,702 2,362 0.0003
2018-08-10 2018-06-30 13F OPKO HEALTH COM 68375N103 0 -287,515 -100.00 0 -100.00
2018-05-14 2018-03-31 13F OPKO HEALTH COM 68375N103 287,515 -324,366 -53.01 911 -69.61 0.0001
2018-02-12 2017-12-31 13F OPKO HEALTH COM 68375N103 611,881 -921,316 -60.09 2,998 -71.50 0.0004
2017-11-13 2017-09-30 13F OPKO HEALTH COM 68375N103 1,533,197 -3,894,983 -71.75 10,518 -70.55 0.0013
2017-08-29 2017-06-30 13F/A-1 OPKO HEALTH COM 68375N103 5,428,180 -295,648 -5.17 35,717 -22.00 0.0044
2017-08-11 2017-06-30 13F OPKO HEALTH COM 68375N103 5,428,180 -295,648 35,717
2017-05-11 2017-03-31 13F OPKO HEALTH COM 68375N103 5,723,828 -2,679,462 -31.89 45,791 -41.41 0.0058
2017-02-10 2016-12-31 13F OPKO HEALTH COM 68375N103 8,403,290 -529,966 -5.93 78,151 -17.39 0.0104
2016-11-14 2016-09-30 13F OPKO HEALTH COM 68375N103 8,933,256 6,855,596 329.97 94,603 387.52 0.0126
2016-08-11 2016-06-30 13F OPKO HEALTH COM 68375N103 2,077,660 0 0.00 19,405 -10.11 0.0026
2016-05-16 2016-03-31 13F OPKO HEALTH COM 68375N103 2,077,660 -1,229,800 -37.18 21,587 -35.06 0.0030
2016-02-12 2015-12-31 13F OPKO HEALTH COM 68375N103 3,307,460 0 0.00 33,240 19.50 0.0045
2015-11-10 2015-09-30 13F OPKO HEALTH COM 68375N103 3,307,460 0 0.00 27,816 -47.70 0.0040
2015-08-25 2015-06-30 13F/A-1 OPKO HEALTH COM 68375N103 3,307,460 0 0.00 53,184 13.48 0.0068
2015-08-13 2015-06-30 13F OPKO HEALTH COM 68375N103 3,307,460 53,184
2015-05-14 2015-03-31 13F OPKO HEALTH COM 68375N103 3,307,460 -80,000 -2.36 46,867 38.49 0.0060
2015-02-17 2014-12-31 13F OPKO HEALTH COM 68375N103 3,387,460 -2,219,200 -39.58 33,841 -29.07 0.0044
2014-11-14 2014-09-30 13F OPKO HEALTH COM 68375N103 5,606,660 1,138,200 25.47 47,713 20.79 0.0065
2014-08-14 2014-06-30 13F OPKO HEALTH COM 68375N103 4,468,460 -359,900 -7.45 39,501 -12.22 0.0053
2014-05-15 2014-03-31 13F OPKO HEALTH COM 68375N103 4,828,360 -2,530,940 -34.39 45,000 -27.55 0.0062
2014-02-13 2013-12-31 13F OPKO HEALTH COM 68375N103 7,359,300 5,307,000 258.59 62,112 243.52 0.0088
2013-11-14 2013-09-30 13F OPKO HEALTH COM 68375N103 2,052,300 -45,100 -2.15 18,081 21.41 0.0028
2013-09-24 2013-06-30 13F/A-1 OPKO HEALTH COM 68375N103 2,097,400 2,097,400 14,892 0.0024
2013-08-14 2013-06-30 13F OPKO HEALTH COM 68375N103 2,097,400 14,892 0.0024
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.