Innoviva, Inc.
DE ˙ DB ˙ US45781M1018
19,20 € ↑0,70 (3,78%)
2026-06-04
DEL PRIS
SecurityDE:HVE / Innoviva, Inc.
InstitutionComerica Bank
Latest Disclosed Ownership16,778 shares
Latest Disclosed Value $ 335,386
Comerica Bank reports 5.09% decrease in ownership of HVE / Innoviva, Inc.

On January 29, 2026 - Comerica Bank filed a 13F-HR form disclosing ownership of 16,778 shares of Innoviva, Inc. (DE:HVE) valued at $278,515 USD as of December 31, 2025. The entity filed a previous 13F-HR on November 14, 2025 disclosing 17,678 shares of Innoviva, Inc.. This represents a change in shares of -5.09% during the quarter. The current value of the position is $322,138 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

Upgrade to unlock premium data and export to Excel .

Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-01-29 2025-12-31 13F INNOVIVA COM 45781M101 16,778 -900 -5.09 335 4.04 0.0011
2025-11-14 2025-09-30 13F INNOVIVA COM 45781M101 17,678 -2,151 -10.85 323 -19.10 0.0012
2025-08-14 2025-06-30 13F INNOVIVA COM 45781M101 19,829 -278 -1.38 398 9.34 0.0015
2025-05-14 2025-03-31 13F INNOVIVA COM 45781M101 20,107 -162 -0.80 365 3.70 0.0015
2025-02-14 2024-12-31 13F/A-1 INNOVIVA COM 45781M101 20,269 -141,150 -87.44 352 -88.74 0.0014
2025-02-14 2024-12-31 13F INNOVIVA COM 45781M101 20,269 -141,150 352 0.0012
2024-11-14 2024-09-30 13F INNOVIVA COM 45781M101 161,419 -55,198 -25.48 3,117 -12.25 0.0123
2024-08-15 2024-06-30 13F INNOVIVA COMMON 45781M101 216,617 32,475 17.64 3,553 26.59 0.0148
2024-05-16 2024-03-31 13F INNOVIVA COMMON 45781M101 184,142 -77,407 -29.60 2,806 -33.11 0.0121
2024-02-14 2023-12-31 13F INNOVIVA COMMON 45781M101 261,549 233,576 835.01 4,195 1,055.65 0.0193
2023-11-21 2023-09-30 13F INNOVIVA COMMON 45781M101 27,973 27,973 363 0.0019
2023-08-22 2023-06-30 13F INNOVIVA COM 45781M101 0 -38,290 -100.00 0 0.0000
2023-01-26 2022-12-31 13F INNOVIVA COM 45781M101 38,290 -11,273 -22.74 1 -100.00 0.0040
2022-10-28 2022-09-30 13F INNOVIVA COM 45781M101 49,563 -5,920 -10.67 683 -16.40 0.0058
2022-08-02 2022-06-30 13F INNOVIVA COM 45781M101 55,483 -355 -0.64 817 -19.98 0.0067
2022-04-27 2022-03-31 13F INNOVIVA COM 45781M101 55,838 1,198 2.19 1,021 21.40 0.0074
2022-02-18 2021-12-31 13F INNOVIVA COM 45781M101 54,640 -3,613 -6.20 841 -11.10 0.0062
2021-11-22 2021-09-30 13F INNOVIVA COM 45781M101 58,253 -2,075 -3.44 946 -2.17 0.0057
2021-08-26 2021-06-30 13F INNOVIVA COM 45781M101 60,328 -4,733 -7.27 967 27.07 0.0058
2021-04-28 2021-03-31 13F INNOVIVA COM 45781M101 65,061 -6,148 -8.63 761 -13.42 0.0045
2021-01-28 2020-12-31 13F INNOVIVA COM 45781M101 71,209 3,935 5.85 879 27.76 0.0056
2020-10-30 2020-09-30 13F INNOVIVA COM 45781M101 67,274 -3,927 -5.52 688 -30.15 0.0050
2020-07-31 2020-06-30 13F INNOVIVA COM 45781M101 71,201 5,687 8.68 985 13.09 0.0076
2020-05-01 2020-03-31 13F INNOVIVA COM 45781M101 65,514 2,816 4.49 871 -0.91 0.0080
2020-02-07 2019-12-31 13F INNOVIVA COM 45781M101 62,698 -104 -0.17 879 31.98 0.0067
2019-10-31 2019-09-30 13F INNOVIVA COM 45781M101 62,802 -1,413 -2.20 666 -23.09 0.0053
2019-08-02 2019-06-30 13F INNOVIVA COM 45781M101 64,215 -3,074 -4.57 866 -9.51 0.0069
2019-05-02 2019-03-31 13F INNOVIVA COM 45781M101 67,289 551 0.83 957 -28.53 0.0078
2019-02-06 2018-12-31 13F INNOVIVA COM 45781M101 66,738 443 0.67 1,339 31.02 0.0114
2018-11-01 2018-09-30 13F INNOVIVA COM 45781M101 66,295 -6,774 -9.27 1,022 -4.40 0.0082
2018-08-01 2018-06-30 13F INNOVIVA COM 45781M101 73,069 52 0.07 1,069 -9.79 0.0075
2018-05-01 2018-03-31 13F INNOVIVA COM 45781M101 73,017 -2,633 -3.48 1,185 1.89 0.0085
2018-02-02 2017-12-31 13F INNOVIVA COM 45781M101 75,650 -2,853 -3.63 1,163 23.99 0.0077
2017-11-06 2017-09-30 13F INNOVIVA COM 45781M101 78,503 -2,882 -3.54 938 -11.17 0.0068
2017-08-03 2017-06-30 13F INNOVIVA COM 45781M101 81,385 -4,565 -5.31 1,056 -2.40 0.0079
2017-05-03 2017-03-31 13F INNOVIVA COM 45781M101 85,950 3,673 4.46 1,082 15.85 0.0082
2017-02-08 2016-12-31 13F INNOVIVA COM 45781M101 82,277 82,277 934 0.0074
2014-08-12 2014-06-30 13F THERAVANCE COM 88338T104 0 -7,580 -100.00 0 -100.00
2014-05-15 2014-03-31 13F THERAVANCE COM 88338T104 7,580 110 1.47 235 -11.65 0.0018
2014-02-11 2013-12-31 13F THERAVANCE COM 88338T104 7,470 -48 -0.64 266 -13.36 0.0021
2013-11-12 2013-09-30 13F THERAVANCE COM 88338T104 7,518 1,715 29.55 307 37.67 0.0021
2013-08-13 2013-06-30 13F/A-1 THERAVANCE COM 88338T104 5,803 5,803 223 0.0018
2013-08-08 2013-06-30 13F THERAVANCE COM 88338T104 17,349 667
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.