Alnylam Pharmaceuticals, Inc.
DE ˙ XTRA ˙ US02043Q1076
251,80 € ↑6,70 (2,73%)
2026-06-03
DEL PRIS
SecurityDE:DUL / Alnylam Pharmaceuticals, Inc.
InstitutionStifel Financial Corp
Latest Disclosed Ownership49,954 shares
Latest Disclosed Value $ 16,528,330
Stifel Financial Corp reports 144.55% increase in ownership of DUL / Alnylam Pharmaceuticals, Inc.

On May 12, 2026 - Stifel Financial Corp filed a 13F-HR form disclosing ownership of 49,954 shares of Alnylam Pharmaceuticals, Inc. (DE:DUL) valued at $14,271,858 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 20,427 shares of Alnylam Pharmaceuticals, Inc.. This represents a change in shares of 144.55% during the quarter. The current value of the position is $12,578,417 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-12 2026-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 49,954 29,527 144.55 16,528 103.50 0.0036
2026-02-13 2025-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 20,427 132 0.65 8,123 -12.23 0.0073
2025-11-12 2025-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 20,295 6,595 48.14 9,254 107.16 0.0084
2025-08-14 2025-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 13,700 6,627 93.69 4,467 134.00 0.0043
2025-05-14 2025-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 7,073 -2,944 -29.39 1,910 -19.01 0.0020
2025-02-13 2024-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 10,017 4,187 71.82 2,357 47.04 0.0025
2024-11-14 2024-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 5,830 -109 -1.84 1,603 11.09 0.0017
2024-08-13 2024-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 5,939 -2,401 -28.79 1,443 15.81 0.0016
2024-05-14 2024-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 8,340 -3,318 -28.46 1,246 -44.15 0.0014
2024-02-12 2023-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 11,658 3,589 44.48 2,232 56.23 0.0028
2023-11-13 2023-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 8,069 -1,253 -13.44 1,429 -19.32 0.0020
2023-08-14 2023-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 9,322 1,611 20.89 1,771 14.64 0.0024
2023-05-12 2023-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 7,711 261 3.50 1,545 -12.77 0.0022
2023-02-13 2022-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 7,450 -2,807 -27.37 1,771 -13.78 0.0027
2022-11-14 2022-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 10,257 673 7.02 2,053 46.96 0.0034
2022-08-15 2022-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 9,584 -2,592 -21.29 1,397 -29.73 0.0022
2022-05-13 2022-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 12,176 -2,500 -17.03 1,988 -20.13 0.0027
2022-02-14 2021-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 14,676 674 4.81 2,489 -5.86 0.0033
2021-11-15 2021-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 14,002 -8,775 -38.53 2,644 -31.54 0.0039
2021-08-13 2021-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 22,777 2,530 12.50 3,862 35.08 0.0058
2021-05-14 2021-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 20,247 4,207 26.23 2,859 37.19 0.0047
2021-02-12 2020-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 16,040 1,310 8.89 2,084 -2.80 0.0037
2020-11-16 2020-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 14,730 1,288 9.58 2,144 7.68 0.0044
2020-08-14 2020-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 13,442 7,116 112.49 1,991 188.97 0.0046
2020-05-14 2020-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 6,326 1,639 34.97 689 27.83 0.0019
2020-02-13 2019-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 4,687 603 14.76 539 64.33 0.0011
2019-11-19 2019-09-30 13F/A-1 ALNYLAM PHARMACEUTICALS COM 02043Q107 4,084 114 2.87 328 13.89 0.0008
2019-11-13 2019-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 4,084 114 328 183.8604
2019-08-14 2019-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 3,970 1,496 60.47 288 24.14 0.0007
2019-05-14 2019-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 2,474 2,474 232 0.0007
2015-11-16 2015-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 0 -3,807 -100.00 0 -100.00
2015-08-17 2015-06-30 13F/A-1 ALNYLAM PHARMACEUTICALS COM 02043Q107 3,807 173 4.76 456 20.32 0.0024
2015-08-17 2015-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 3,807 456
2015-05-14 2015-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 3,634 3,634 379 0.0021
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.