Alnylam Pharmaceuticals, Inc.
DE ˙ XTRA ˙ US02043Q1076
260,50 € ↑8,70 (3,46%)
2026-06-04
DEL PRIS
SecurityDE:DUL / Alnylam Pharmaceuticals, Inc.
InstitutionPrincipal Securities, Inc.
Latest Disclosed Ownership2,745 shares
Latest Disclosed Value $ 908,238
Principal Securities, Inc. reports 4.53% increase in ownership of DUL / Alnylam Pharmaceuticals, Inc.

On May 13, 2026 - Principal Securities, Inc. filed a 13F-HR form disclosing ownership of 2,745 shares of Alnylam Pharmaceuticals, Inc. (DE:DUL) valued at $784,246 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 12, 2026 disclosing 2,626 shares of Alnylam Pharmaceuticals, Inc.. This represents a change in shares of 4.53% during the quarter. The current value of the position is $715,072 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-13 2026-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 2,745 119 4.53 908 -13.03 0.0133
2026-02-12 2025-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 2,626 188 7.71 1,044 -6.03 0.0161
2025-11-12 2025-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 2,438 724 42.24 1,112 99.10 0.0183
2025-08-11 2025-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 1,714 527 44.40 559 100.00 0.0105
2025-04-30 2025-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 1,187 0 0.00 279 0.00 0.0062
2025-01-30 2024-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 1,187 1,066 880.99 279 745.45 0.0063
2024-10-28 2024-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 121 6 5.22 33 22.22 0.0008
2024-07-31 2024-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 115 25 27.78 28 107.69 0.0008
2024-05-10 2024-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 90 -12 -11.76 13 -31.58 0.0004
2024-05-10 2023-12-31 13F/A-1 ALNYLAM PHARMACEUTICALS COM 02043Q107 102 102 20 0.0007
2024-02-07 2023-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 102 102 20 0.0007
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.