Alnylam Pharmaceuticals, Inc.
DE ˙ XTRA ˙ US02043Q1076
260,50 € ↑8,70 (3,46%)
2026-06-04
DEL PRIS
SecurityDE:DUL / Alnylam Pharmaceuticals, Inc.
InstitutionPnc Financial Services Group, Inc.
Latest Disclosed Ownership12,322 shares
Latest Disclosed Value $ 4,077,037
Pnc Financial Services Group, Inc. reports 2.81% decrease in ownership of DUL / Alnylam Pharmaceuticals, Inc.

On May 8, 2026 - Pnc Financial Services Group, Inc. filed a 13F-HR form disclosing ownership of 12,322 shares of Alnylam Pharmaceuticals, Inc. (DE:DUL) valued at $3,520,395 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 6, 2026 disclosing 12,678 shares of Alnylam Pharmaceuticals, Inc.. This represents a change in shares of -2.81% during the quarter. The current value of the position is $3,209,881 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-08 2026-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 12,322 -356 -2.81 4,077 -19.12 0.0024
2026-02-06 2025-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 12,678 -437 -3.33 5,041 -15.70 0.0028
2025-11-07 2025-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 13,115 -55 -0.42 5,981 39.26 0.0036
2025-08-08 2025-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 13,170 45 0.34 4,295 21.16 0.0028
2025-05-09 2025-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 13,125 585 4.67 3,544 20.14 0.0019
2025-02-07 2024-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 12,540 -3 -0.02 2,951 -14.47 0.0020
2024-11-08 2024-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 12,543 144 1.16 3,450 14.51 0.0022
2024-08-09 2024-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 12,399 212 1.74 3,013 65.40 0.0020
2024-05-10 2024-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 12,187 -931 -7.10 1,821 -27.45 0.0013
2024-03-22 2023-12-31 13F/A-1 ALNYLAM PHARMACEUTICALS COM 02043Q107 13,118 -2,547 -16.26 2,511 -9.52 0.0020
2024-02-09 2023-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 13,118 -2,547 2,511 0.0004
2023-11-13 2023-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 15,665 -39 -0.25 2,774 -6.98 0.0024
2023-08-11 2023-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 15,704 96 0.62 2,983 -4.61 0.0025
2023-05-15 2023-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 15,608 25 0.16 3,127 -15.58 0.0027
2023-02-10 2022-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 15,583 -214 -1.35 3,703 17.11 0.0036
2022-11-10 2022-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 15,797 -559 -3.42 3,162 32.52 0.0033
2022-08-12 2022-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 16,356 846 5.45 2,386 -5.80 0.0023
2022-05-12 2022-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 15,510 1 0.01 2,533 -3.69 0.0022
2022-02-11 2021-12-31 13F ALNYLAM Common Stock 02043Q107 15,509 6 0.04 2,630 -10.12 0.0022
2021-11-05 2021-09-30 13F ALNYLAM Common Stock 02043Q107 15,503 -499 -3.12 2,926 7.89 0.0027
2021-08-06 2021-06-30 13F ALNYLAM Common Stock 02043Q107 16,002 107 0.67 2,712 20.80 0.0025
2021-05-07 2021-03-31 13F ALNYLAM Common Stock 02043Q107 15,895 1,504 10.45 2,245 19.99 0.0022
2021-02-12 2020-12-31 13F ALNYLAM Common Stock 02043Q107 14,391 8,321 137.08 1,871 111.89 0.0019
2020-11-06 2020-09-30 13F ALNYLAM Common Stock 02043Q107 6,070 -779 -11.37 883 -12.83 0.0011
2020-08-28 2020-06-30 13F/A-1 ALNYLAM Common Stock 02043Q107 6,849 -6,433 -48.43 1,013 -29.90 0.0013
2020-08-07 2020-06-30 13F ALNYLAM Common Stock 02043Q107 6,849 -6,433 1,013 210.3377
2020-05-08 2020-03-31 13F ALNYLAM Common Stock 02043Q107 13,282 4,262 47.25 1,445 38.94 0.0018
2020-02-07 2019-12-31 13F ALNYLAM Common Stock 02043Q107 9,020 57 0.64 1,040 44.24 0.0010
2019-11-08 2019-09-30 13F ALNYLAM Common Stock 02043Q107 8,963 84 0.95 721 12.13 0.0007
2019-08-09 2019-06-30 13F ALNYLAM Common Stock 02043Q107 8,879 108 1.23 643 -21.59 0.0006
2019-05-10 2019-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 8,771 55 0.63 820 29.13 0.0008
2019-02-08 2018-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 8,716 55 0.64 635 -16.23 0.0007
2018-11-09 2018-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 8,661 6 0.07 758 -11.03 0.0007
2018-08-10 2018-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 8,655 -193 -2.18 852 -19.09 0.0008
2018-05-11 2018-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 8,848 -16 -0.18 1,053 -6.40 0.0010
2018-02-09 2017-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 8,864 65 0.74 1,125 8.91 0.0011
2017-11-13 2017-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 8,799 -471 -5.08 1,033 39.78 0.0011
2017-08-11 2017-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 9,270 585 6.74 739 65.70 0.0008
2017-05-12 2017-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 8,685 36 0.42 446 38.51 0.0005
2017-02-10 2016-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 8,649 -128 -1.46 322 -45.88 0.0004
2016-11-04 2016-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 8,777 0 0.00 595 22.18 0.0007
2016-08-05 2016-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 8,777 464 5.58 487 -6.88 0.0006
2016-05-06 2016-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 8,313 0 0.00 523 -33.12 0.0006
2016-02-05 2015-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 8,313 8,313 0.00 782 0.0009
2015-02-06 2014-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 0 -177 -100.00 0 -100.00
2014-11-07 2014-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 177 0 0.00 14 27.27 0.0000
2014-08-08 2014-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 177 0 0.00 11 -8.33 0.0000
2014-05-09 2014-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 177 177 12 0.0000
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.