Alnylam Pharmaceuticals, Inc.
DE ˙ XTRA ˙ US02043Q1076
251,80 € ↑6,70 (2,73%)
2026-06-03
DEL PRIS
SecurityDE:DUL / Alnylam Pharmaceuticals, Inc.
InstitutionNatixis
Latest Disclosed Ownership17,076 shares
Latest Disclosed Value $ 5,649,936
Natixis reports 57.07% decrease in ownership of DUL / Alnylam Pharmaceuticals, Inc.

On May 14, 2026 - Natixis filed a 13F-HR form disclosing ownership of 17,076 shares of Alnylam Pharmaceuticals, Inc. (DE:DUL) valued at $4,878,613 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 39,779 shares of Alnylam Pharmaceuticals, Inc.. This represents a change in shares of -57.07% during the quarter. The current value of the position is $4,299,737 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-14 2026-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 17,076 -22,703 -57.07 5,650 -64.29 0.0183
2026-02-13 2025-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 39,779 39,779 15,818 0.0562
2024-11-13 2024-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 0 -291 -100.00 0 -100.00
2024-08-13 2024-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 291 -391 -57.33 71 -30.69 0.0004
2024-05-13 2024-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 682 682 102 0.0005
2023-05-12 2023-03-31 13F Alnylam Pharmaceuticals COM 02043Q107 0 -464,510 -100.00 0 -100.00
2023-02-13 2022-12-31 13F Alnylam Pharmaceuticals COM 02043Q107 464,510 238,476 105.50 109,754 142.51 0.2557
2022-11-14 2022-09-30 13F Alnylam Pharmaceuticals COM 02043Q107 226,034 218,295 2,820.71 45,257 3,908.59 0.2118
2022-08-12 2022-06-30 13F Alnylam Pharmaceuticals COM 02043Q107 7,739 5,373 227.09 1,129 192.49 0.0041
2022-05-13 2022-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 2,366 -101,696 -97.73 386 -97.81 0.0013
2022-02-14 2021-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 104,062 1,546 1.51 17,647 -8.83 0.0602
2021-11-12 2021-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 102,516 94,044 1,110.06 19,356 1,247.91 0.0669
2021-08-13 2021-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 8,472 1,961 30.12 1,436 56.26 0.0063
2021-05-14 2021-03-31 13F ALNYLAM PHARMACEUTICALS CO 02043Q107 6,511 4,525 227.84 919 256.20 0.0030
2021-02-12 2020-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 1,986 -616 -23.67 258 -31.93 0.0009
2020-11-12 2020-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 2,602 2,602 379 0.0028
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.