Alnylam Pharmaceuticals, Inc.
DE ˙ XTRA ˙ US02043Q1076
260,50 € ↑8,70 (3,46%)
2026-06-04
DEL PRIS
SecurityDE:DUL / Alnylam Pharmaceuticals, Inc.
InstitutionJacobs Levy Equity Management, Inc
Latest Disclosed Ownership212,204 shares
Latest Disclosed Value $ 70,211,937
Jacobs Levy Equity Management, Inc reports 47.13% decrease in ownership of DUL / Alnylam Pharmaceuticals, Inc.

On May 15, 2026 - Jacobs Levy Equity Management, Inc filed a 13F-HR form disclosing ownership of 212,204 shares of Alnylam Pharmaceuticals, Inc. (DE:DUL) valued at $60,626,683 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 13, 2026 disclosing 401,371 shares of Alnylam Pharmaceuticals, Inc.. This represents a change in shares of -47.13% during the quarter. The current value of the position is $55,279,142 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 212,204 -189,167 -47.13 70,212 -56.01 0.2952
2026-02-13 2025-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 401,371 -8,971 -2.19 159,605 -14.70 0.6163
2025-11-17 2025-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 410,342 392,668 2,221.73 187,116 3,146.83 0.7434
2025-08-14 2025-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 17,674 -135,296 -88.45 5,763 -86.05 0.0226
2025-05-15 2025-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 152,970 152,970 41,305 0.1638
2024-11-14 2024-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 0 -13,283 -100.00 0 -100.00
2024-08-14 2024-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 13,283 -113,084 -89.49 3,228 -82.91 0.0133
2024-05-15 2024-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 126,367 126,367 18,886 0.0844
2022-11-15 2022-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 0 -8,604 -100.00 0 -100.00
2022-08-15 2022-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 8,604 -22,670 -72.49 1,255 -75.43 0.0097
2022-05-16 2022-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 31,274 -36,472 -53.84 5,107 -55.54 0.0344
2022-02-14 2021-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 67,746 67,746 11,488 0.0769
2021-11-15 2021-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 0 -1,525 -100.00 0 -100.00
2021-08-16 2021-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 1,525 -6,777 -81.63 259 -77.90 0.0018
2021-05-17 2021-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 8,302 -710 -7.88 1,172 0.09 0.0090
2021-02-16 2020-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 9,012 2,259 33.45 1,171 19.13 0.0103
2020-11-16 2020-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 6,753 6,753 983 0.0102
2020-02-14 2019-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 0 -102,590 -100.00 0 -100.00
2019-11-14 2019-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 102,590 102,590 8,250 0.1013
2017-05-12 2017-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 0 -12,100 -100.00 0 -100.00
2017-02-14 2016-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 12,100 12,100 0.00 453 0.0087
2016-11-14 2016-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 0 -25,061 -100.00 0 -100.00
2016-08-15 2016-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 25,061 -138,530 -84.68 1,391 -86.45 0.0288
2016-05-16 2016-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 163,591 163,591 0.00 10,269 0.2175
2015-11-16 2015-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 0 -3,940 -100.00 0 -100.00
2015-08-14 2015-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 3,940 -3,500 -47.04 472 -39.25 0.0090
2015-05-15 2015-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 7,440 7,440 777 0.0132
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.