Alnylam Pharmaceuticals, Inc.
DE ˙ XTRA ˙ US02043Q1076
260,50 € ↑8,70 (3,46%)
2026-06-04
DEL PRIS
SecurityDE:DUL / Alnylam Pharmaceuticals, Inc.
InstitutionGeode Capital Management, Llc
Latest Disclosed Ownership2,660,385 shares
Latest Disclosed Value $ 884,565,832
Geode Capital Management, Llc reports 0.36% increase in ownership of DUL / Alnylam Pharmaceuticals, Inc.

On May 15, 2026 - Geode Capital Management, Llc filed a 13F-HR form disclosing ownership of 2,660,385 shares of Alnylam Pharmaceuticals, Inc. (DE:DUL) valued at $760,071,994 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 9, 2026 disclosing 2,650,722 shares of Alnylam Pharmaceuticals, Inc.. This represents a change in shares of 0.36% during the quarter. The current value of the position is $693,030,292 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 2,660,385 9,663 0.36 884,566 -16.30 0.0294
2026-02-09 2025-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 2,650,722 151,480 6.06 1,056,884 -7.00 0.0652
2025-11-12 2025-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 2,499,242 100,472 4.19 1,136,406 45.72 0.0725
2025-08-08 2025-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 2,398,770 75,936 3.27 779,857 24.61 0.0547
2025-05-13 2025-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 2,322,834 116,034 5.26 625,817 20.73 0.0492
2025-02-12 2024-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 2,206,800 59,597 2.78 518,367 -12.02 0.0402
2024-11-12 2024-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 2,147,203 66,928 3.22 589,209 16.77 0.0477
2024-08-09 2024-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 2,080,275 78,557 3.92 504,599 68.92 0.0443
2024-05-13 2024-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 2,001,718 74,982 3.89 298,725 -18.87 0.0276
2024-02-13 2023-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 1,926,736 87,231 4.74 368,199 13.17 0.0385
2023-11-13 2023-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 1,839,505 37,483 2.08 325,349 -4.79 0.0388
2023-08-11 2023-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 1,802,022 63,907 3.68 341,708 -1.72 0.0402
2023-05-15 2023-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 1,738,115 48,186 2.85 347,684 86,603.99 0.0451
2023-02-13 2022-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 1,689,929 90,455 5.66 401 -99.87 0.0563
2022-11-14 2022-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 1,599,474 26,771 1.70 319,896 39.63 0.0485
2022-08-12 2022-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 1,572,703 2,420 0.15 229,108 -10.51 0.0336
2022-05-13 2022-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 1,570,283 64,992 4.32 256,023 0.44 0.0320
2022-02-11 2021-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 1,505,291 51,272 3.53 254,889 -7.02 0.0307
2021-11-12 2021-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 1,454,019 8,001 0.55 274,123 12.00 0.0369
2021-08-13 2021-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 1,446,018 59,719 4.31 244,756 25.22 0.0337
2021-05-12 2021-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 1,386,299 77,166 5.89 195,454 15.02 0.0299
2021-02-12 2020-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 1,309,133 49,330 3.92 169,928 -7.27 0.0285
2020-11-13 2020-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 1,259,803 -24,493 -1.91 183,252 -3.58 0.0359
2020-08-13 2020-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 1,284,296 -69,632 -5.14 190,053 29.06 0.0407
2020-05-14 2020-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 1,353,928 114,441 9.23 147,257 3.25 0.0384
2020-02-20 2019-12-31 13F/A-1 ALNYLAM PHARMACEUTICALS COM 02043Q107 1,239,487 50,788 4.27 142,622 49.30 0.0298
2020-02-13 2019-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 1,239,487 50,788 142,622 18,175.9234
2019-11-12 2019-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 1,188,699 128,504 12.12 95,528 24.26 0.0223
2019-08-14 2019-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 1,060,195 53,973 5.36 76,878 -18.19 0.0186
2019-05-14 2019-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 1,006,222 90,689 9.91 93,966 40.86 0.0243
2019-03-06 2018-12-31 13F/A-1 ALNYLAM PHARMACEUTICALS COM 02043Q107 915,533 34,770 3.95 66,708 -13.41 0.0206
2019-02-13 2018-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 915,533 34,770 66,708
2018-11-13 2018-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 880,763 74,018 9.17 77,037 -2.98 0.0217
2018-08-14 2018-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 806,745 41,401 5.41 79,400 -12.83 0.0244
2018-05-15 2018-03-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 765,344 17,698 2.37 91,090 -4.04 0.0297
2018-02-13 2017-12-31 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 747,646 88,119 13.36 94,929 22.51 0.0322
2017-11-14 2017-09-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 659,527 -2,878 -0.43 77,487 46.66 0.0286
2017-08-14 2017-06-30 13F ALNYLAM PHARMACEUTICALS COM 02043Q107 662,405 85,608 14.84 52,833 78.73 0.0208
2017-06-21 2017-03-31 13F/A-1 ALNYLAM PHARMACEUTICALS INC COM COM 02043Q107 576,797 42,781 8.01 29,560 47.85 0.0121
2017-05-12 2017-03-31 13F ALNYLAM PHARMACEUTICALS INC COM COM 02043Q107 576,797 29,560
2017-02-14 2016-12-31 13F ALNYLAM PHARMACEUTICALS INC COM COM 02043Q107 534,016 14,111 2.71 19,993 -43.24 0.0093
2016-11-10 2016-09-30 13F ALNYLAM PHARMACEUTICALS INC COM COM 02043Q107 519,905 20,289 4.06 35,225 27.12 0.0177
2016-08-12 2016-06-30 13F ALNYLAM PHARMACEUTICALS INC COM COM 02043Q107 499,616 19,435 4.05 27,710 -8.01 0.0151
2016-05-13 2016-03-31 13F ALNYLAM PHARMACEUTICALS INC COM COM 02043Q107 480,181 31,627 7.05 30,123 -28.62 0.0160
2016-02-12 2015-12-31 13F ALNYLAM PHARMACEUTICALS INC COM COM 02043Q107 448,554 10,371 2.37 42,199 19.92 0.0240
2015-11-13 2015-09-30 13F ALNYLAM PHARMACEUTICALS INC COM COM 02043Q107 438,183 3,827 0.88 35,188 -32.37 0.0213
2015-08-14 2015-06-30 13F ALNYLAM PHARMACEUTICALS INC COM COM 02043Q107 434,356 23,380 5.69 52,033 21.25 0.0297
2015-05-14 2015-03-31 13F ALNYLAM PHARMACEUTICALS INC COM COM 02043Q107 410,976 63,014 18.11 42,914 27.15 0.0245
2015-02-12 2014-12-31 13F ALNYLAM PHARMACEUTICALS INC COM COM 02043Q107 347,962 18,137 5.50 33,752 31.03 0.0201
2014-11-14 2014-09-30 13F ALNYLAM PHARMACEUTICALS INC COM COM 02043Q107 329,825 5,617 1.73 25,759 25.78 0.0167
2014-08-13 2014-06-30 13F ALNYLAM PHARMACEUTICALS INC COM COM 02043Q107 324,208 10,614 3.38 20,480 -2.73 0.0132
2014-05-14 2014-03-31 13F ALNYLAM PHARMACEUTICALS INC COM COM 02043Q107 313,594 28,989 10.19 21,054 15.00 0.0141
2014-02-14 2013-12-31 13F ALNYLAM PHARMACEUTICALS INC COM COM 02043Q107 284,605 32,238 12.77 18,308 13.33 0.0127
2013-11-14 2013-09-30 13F ALNYLAM PHARMACEUTICALS INC COM COM 02043Q107 252,367 32,709 14.89 16,154 137.14 0.0130
2013-08-14 2013-06-30 13F ALNYLAM PHARMACEUTICALS INC COM COM 02043Q107 219,658 219,658 6,812 0.0060
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.