Guardant Health, Inc.
DE ˙ DB ˙ US40131M1099
111,48 € ↑2,18 (1,99%)
2026-06-05
DEL PRIS
SecurityDE:5GH / Guardant Health, Inc.
InstitutionHsbc Holdings Plc
Latest Disclosed Ownership98,843 shares
Latest Disclosed Value $ 9,130,128
Hsbc Holdings Plc ownership in 5GH / Guardant Health, Inc.

On April 30, 2026 - Hsbc Holdings Plc filed a 13F-HR form disclosing ownership of 98,843 shares of Guardant Health, Inc. (DE:5GH) valued at $7,446,832 USD as of March 31, 2026. The entity filed a previous 13F-HR/A on March 20, 2026 disclosing 8,451 shares of Guardant Health, Inc.. This represents a change in shares of 1,069.60% during the quarter. The current value of the position is $11,019,018 USD.

Hsbc Holdings Plc has a history of taking positions in derivatives of the underlying security (5GH) in the form of stock options. The firm currently holds call options representing 0 of underlying shares valued at $0 USD and put options representing 0 of underlying shares valued at $0 USD .

Note: prior versions of this page mistakenly stated that the share values represented the number of options, not the number of underlying shares. For more information on the data backing these reports, please see the SEC document Frequently Asked Questions About Form 13F.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

Upgrade to unlock premium data and export to Excel .

Institutional Put/Call Ratios
(Premium Subscription Required)

In addition to reporting standard equity and debt issues, institutions with more than 100MM assets under management must also disclose their put and call option holdings. Since put options generally indicate negative sentiment, and call options indicate positive sentiment, we can get a sense of the overall institutional sentiment by plotting the ratio of puts to calls. The chart to the right plots the historical put/call ratio for this instrument.

Using Put/Call Ratio as an indicator of investor sentiment overcomes one of the key deficiencies of using total institutional ownership, which is that a significant amount of assets under management are invested passively to track indices. Passively-managed funds do not typically buy options, so the put/call ratio indicator more closely tracks the sentiment of actively-managed funds.

DE:5GH / Guardant Health, Inc. Historical Put/Call Ratio
Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-04-30 2026-03-31 13F GUARDANT HEALTH COM 40131M109 98,843 90,392 1,069.60 9,130 957.94 0.0006
2026-03-20 2025-12-31 13F/A-1 GUARDANT HEALTH COM 40131M109 8,451 2,743 48.06 863 143.10 0.0000
2026-03-06 2025-12-31 13F GUARDANT HEALTH COM 40131M109 8,451 2,743 48.06 863 143.10 0.0000
2025-11-13 2025-09-30 13F GUARDANT HEALTH COM 40131M109 5,708 -46,334 -89.03 356 -86.81 0.0002
2025-08-13 2025-06-30 13F GUARDANT HEALTH COM 40131M109 52,042 33,230 176.64 2,693 236.92 0.0016
2025-05-14 2025-03-31 13F GUARDANT HEALTH COM 40131M109 18,812 -199 -1.05 800 37.29 0.0005
2025-02-14 2024-12-31 13F GUARDANT HEALTH COM 40131M109 19,011 3,863 25.50 582 68.21 0.0003
2024-11-14 2024-09-30 13F GUARDANT HEALTH COM 40131M109 15,148 -54,598 -78.28 347 -82.82 0.0002
2024-08-12 2024-06-30 13F GUARDANT HEALTH COM 40131M109 69,746 -22,421 -24.33 2,014 5.94 0.0012
2024-05-15 2024-03-31 13F GUARDANT HEALTH COM 40131M109 92,167 48,635 111.72 1,901 60.83 0.0013
2024-02-12 2023-12-31 13F GUARDANT HEALTH COM 40131M109 43,532 26,191 151.04 1,182 132.68 0.0010
2023-11-13 2023-09-30 13F GUARDANT HEALTH COM 40131M109 17,341 -23,309 -57.34 508 -65.25 0.0005
2023-08-11 2023-06-30 13F GUARDANT HEALTH COM 40131M109 40,650 23,726 140.19 1,462 267.34 0.0015
2023-05-15 2023-03-31 13F GUARDANT HEALTH COM 40131M109 16,924 16,924 398 0.0005
2023-02-14 2022-12-31 13F GUARDANT HEALTH COM 40131M109 0 -19,485 -100.00 0 -100.00
2022-11-14 2022-09-30 13F GUARDANT HEALTH COM 40131M109 19,485 0 0.00 1,049 33.46 0.0017
2022-08-11 2022-06-30 13F GUARDANT HEALTH COM 40131M109 19,485 -931 -4.56 786 -41.95 0.0011
2022-05-16 2022-03-31 13F GUARDANT HEALTH COM 40131M109 20,416 5,295 35.02 1,354 -10.45 0.0016
2022-02-11 2021-12-31 13F GUARDANT HEALTH COM 40131M109 15,121 2,628 21.04 1,512 -3.51 0.0014
2021-11-12 2021-09-30 13F GUARDANT HEALTH COM 40131M109 12,493 -3,448 -21.63 1,567 -20.82 0.0016
2021-08-13 2021-06-30 13F GUARDANT HEALTH COM 40131M109 15,941 8,931 127.40 1,979 82.73 0.0021
2021-05-14 2021-03-31 13F GUARDANT HEALTH COM 40131M109 7,010 -6,788 -49.20 1,083 -38.81 0.0013
2021-02-25 2020-12-31 13F/A-1 GUARDANT HEALTH COM 40131M109 13,798 11,506 502.01 1,770 588.72 0.0024
2021-02-12 2020-12-31 13F GUARDANT HEALTH COM 40131M109 13,798 11,506 1,770 420.2631
2020-11-12 2020-09-30 13F GUARDANT HEALTH COM 40131M109 2,292 2,292 257 0.0004
Disclosed Call Options
File
Date
Effective
Date
Form Security Class ID Opt Avg Share
Price
Shares ΔShares
(%)
Value
(x1000)
ΔValue
(%)
Prior Allocation
(%)
Allocation
(%)
ΔAllocation
(%)
Cost Basis
(x1000)
Profit
(x1000)
Return
(%)
2022-05-16 2022-03-31 13F GUARDANT HEALTH COM Call 0 -100.00 0 -100.00 n/a n/a n/a
2022-02-11 2021-12-31 13F GUARDANT HEALTH COM Call 2,100 212 n/a n/a n/a
Disclosed Put Options
File
Date
Effective
Date
Form Security Class ID Opt Avg Share Price Shares ΔShares
(%)
Value
(x1000)
ΔValue
(%)
Prior Allocation
(%)
Allocation
(%)
ΔAllocation
(%)
Cost Basis
(x1000)
Profit
(x1000)
Return
(%)
2022-05-16 2022-03-31 13F GUARDANT HEALTH COM Put 0 -100.00 0 -100.00 n/a n/a n/a
2022-02-11 2021-12-31 13F GUARDANT HEALTH COM Put 1,300 131 n/a n/a n/a
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.