Guardant Health, Inc.
DE ˙ DB ˙ US40131M1099
111,48 € ↑1,98 (1,81%)
2026-06-03
DEL PRIS
SecurityDE:5GH / Guardant Health, Inc.
InstitutionJanus Henderson Group Plc
Latest Disclosed Ownership140,345 shares
Latest Disclosed Value $ 12,959,851
Janus Henderson Group Plc reports 19.44% increase in ownership of 5GH / Guardant Health, Inc.

On May 18, 2026 - Janus Henderson Group Plc filed a 13F-HR/A form disclosing ownership of 140,345 shares of Guardant Health, Inc. (DE:5GH) valued at $10,573,592 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 117,501 shares of Guardant Health, Inc.. This represents a change in shares of 19.44% during the quarter. The current value of the position is $15,645,661 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-18 2026-03-31 13F/A-1 GUARDANT HEALTH COM 40131M109 140,345 22,844 19.44 12,960 7.99 0.0062
2026-05-15 2026-03-31 13F GUARDANT HEALTH COM 40131M109 140,345 22,844 12,960 0.0024
2026-02-17 2025-12-31 13F GUARDANT HEALTH COM 40131M109 117,501 52,950 82.03 12,001 197.47 0.0054
2025-11-14 2025-09-30 13F GUARDANT HEALTH COM 40131M109 64,551 -7,334 -10.20 4,034 7.83 0.0018
2025-08-14 2025-06-30 13F GUARDANT HEALTH COM 40131M109 71,885 15,207 26.83 3,741 52.94 0.0018
2025-05-15 2025-03-31 13F GUARDANT HEALTH COM 40131M109 56,678 0 0.00 2,447 41.31 0.0013
2025-02-14 2024-12-31 13F GUARDANT HEALTH COM 40131M109 56,678 -3,900 -6.44 1,732 24.62 0.0009
2024-11-14 2024-09-30 13F GUARDANT HEALTH COM 40131M109 60,578 8,432 16.17 1,390 -7.71 0.0007
2024-08-14 2024-06-30 13F GUARDANT HEALTH COM 40131M109 52,146 -603 -1.14 1,505 38.45 0.0008
2024-05-15 2024-03-31 13F GUARDANT HEALTH COM 40131M109 52,749 20 0.04 1,087 -23.77 0.0006
2024-02-14 2023-12-31 13F GUARDANT HEALTH COM 40131M109 52,729 -88 -0.17 1,427 -8.82 0.0009
2023-11-14 2023-09-30 13F GUARDANT HEALTH COM 40131M109 52,817 92 0.17 1,565 -17.07 0.0010
2023-08-14 2023-06-30 13F GUARDANT HEALTH COM 40131M109 52,725 14,547 38.10 1,887 110.73 0.0012
2023-05-15 2023-03-31 13F GUARDANT HEALTH COM 40131M109 38,178 18,661 95.61 895 68.87 0.0006
2023-02-14 2022-12-31 13F GUARDANT HEALTH COM 40131M109 19,517 2,099 12.05 530 -43.44 0.0004
2023-01-13 2022-09-30 13F/A-1 GUARDANT HEALTH COM 40131M109 17,418 18 0.10 937 33.48 0.0007
2022-11-14 2022-09-30 13F GUARDANT HEALTH COM 40131M109 17,418 18 937 0.0007
2022-08-15 2022-06-30 13F GUARDANT HEALTH COM 40131M109 17,400 -94,548 -84.46 702 -90.53 0.0005
2022-05-16 2022-03-31 13F GUARDANT HEALTH COM 40131M109 111,948 18,452 19.74 7,416 -20.69 0.0036
2022-02-14 2021-12-31 13F GUARDANT HEALTH COM 40131M109 93,496 38,673 70.54 9,351 36.45 0.0039
2021-11-16 2021-09-30 13F GUARDANT HEALTH COM 40131M109 54,823 -99,210 -64.41 6,853 -64.18 0.0030
2021-08-16 2021-06-30 13F GUARDANT HEALTH COM 40131M109 154,033 -82,829 -34.97 19,131 -47.09 0.0082
2021-05-17 2021-03-31 13F GUARDANT HEALTH COM 40131M109 236,862 14,919 6.72 36,157 26.41 0.0165
2021-02-16 2020-12-31 13F GUARDANT HEALTH COM 40131M109 221,943 149,171 204.98 28,604 251.66 0.0133
2020-11-16 2020-09-30 13F GUARDANT HEALTH COM 40131M109 72,772 72,772 8,134 0.0042
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.