Guardant Health, Inc.
DE ˙ DB ˙ US40131M1099
111,48 € ↑2,18 (1,99%)
2026-06-05
DEL PRIS
SecurityDE:5GH / Guardant Health, Inc.
InstitutionGoldman Sachs Group Inc
Latest Disclosed Ownership4,435,839 shares
Latest Disclosed Value $ 409,738,481
Goldman Sachs Group Inc ownership in 5GH / Guardant Health, Inc.

On May 15, 2026 - Goldman Sachs Group Inc filed a 13F-HR form disclosing ownership of 4,435,839 shares of Guardant Health, Inc. (DE:5GH) valued at $334,196,110 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 10, 2026 disclosing 2,627,573 shares of Guardant Health, Inc.. This represents a change in shares of 68.82% during the quarter. The current value of the position is $494,507,332 USD.

Goldman Sachs Group Inc has a history of taking positions in derivatives of the underlying security (5GH) in the form of stock options. The firm currently holds call options representing 0 of underlying shares valued at $0 USD and put options representing 0 of underlying shares valued at $0 USD .

Note: prior versions of this page mistakenly stated that the share values represented the number of options, not the number of underlying shares. For more information on the data backing these reports, please see the SEC document Frequently Asked Questions About Form 13F.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Institutional Put/Call Ratios
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In addition to reporting standard equity and debt issues, institutions with more than 100MM assets under management must also disclose their put and call option holdings. Since put options generally indicate negative sentiment, and call options indicate positive sentiment, we can get a sense of the overall institutional sentiment by plotting the ratio of puts to calls. The chart to the right plots the historical put/call ratio for this instrument.

Using Put/Call Ratio as an indicator of investor sentiment overcomes one of the key deficiencies of using total institutional ownership, which is that a significant amount of assets under management are invested passively to track indices. Passively-managed funds do not typically buy options, so the put/call ratio indicator more closely tracks the sentiment of actively-managed funds.

DE:5GH / Guardant Health, Inc. Historical Put/Call Ratio
Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F GUARDANT HEALTH CMN 40131M109 4,435,839 1,808,266 68.82 409,738 52.67 0.0110
2026-02-10 2025-12-31 13F GUARDANT HEALTH CMN 40131M109 2,627,573 1,121,363 74.45 268,380 185.18 0.0331
2025-11-14 2025-09-30 13F GUARDANT HEALTH CMN 40131M109 1,506,210 359,505 31.35 94,108 57.70 0.0115
2025-08-14 2025-06-30 13F GUARDANT HEALTH CMN 40131M109 1,146,705 -20,577 -1.76 59,675 20.01 0.0081
2025-06-27 2025-03-31 13F/A-2 GUARDANT HEALTH CMN 40131M109 1,167,282 -323,443 -21.70 49,726 9.19 0.0080
2025-05-16 2025-03-31 13F/A-1 GUARDANT HEALTH CMN 40131M109 1,167,282 -323,443 49,726 0.0080
2025-05-09 2025-03-31 13F GUARDANT HEALTH CMN 40131M109 1,167,282 -323,443 49,726 0.0015
2025-02-11 2024-12-31 13F GUARDANT HEALTH CMN 40131M109 1,490,725 263,833 21.50 45,542 61.81 0.0072
2024-11-14 2024-09-30 13F GUARDANT HEALTH CMN 40131M109 1,226,892 -21,158 -1.70 28,145 -21.92 0.0045
2024-08-13 2024-06-30 13F GUARDANT HEALTH CMN 40131M109 1,248,050 47,250 3.93 36,044 45.50 0.0061
2024-05-15 2024-03-31 13F GUARDANT HEALTH CMN 40131M109 1,200,800 291,030 31.99 24,773 0.66 0.0044
2024-05-14 2023-12-31 13F/A-2 GUARDANT HEALTH CMN 40131M109 909,770 -44,165 -4.63 24,609 -12.96 0.0045
2024-03-01 2023-12-31 13F/A-1 GUARDANT HEALTH CMN 40131M109 909,770 -44,165 24,609 0.0044
2024-02-13 2023-12-31 13F GUARDANT HEALTH CMN 40131M109 909,770 -44,165 24,609 0.0012
2024-05-15 2023-09-30 13F/A-1 GUARDANT HEALTH CMN 40131M109 953,935 322,171 51.00 28,275 25.01 0.0060
2023-11-14 2023-09-30 13F GUARDANT HEALTH CMN 40131M109 953,935 322,171 28,275 0.0057
2024-05-14 2023-06-30 13F/A-1 GUARDANT HEALTH CMN 40131M109 631,764 -301,066 -32.27 22,617 3.44 0.0048
2023-08-15 2023-06-30 13F GUARDANT HEALTH CMN 40131M109 631,764 -301,066 22,617 0.0046
2024-05-14 2023-03-31 13F/A-1 GUARDANT HEALTH CMN 40131M109 932,830 55,801 6.36 21,866 -8.34 0.0050
2023-05-11 2023-03-31 13F GUARDANT HEALTH CMN 40131M109 932,830 55,801 21,866 0.0047
2024-05-14 2022-12-31 13F/A-1 GUARDANT HEALTH CMN 40131M109 877,029 -268,690 -23.45 23,855 39,006.56 0.0058
2023-02-13 2022-12-31 13F GUARDANT HEALTH CMN 40131M109 877,029 -268,690 23,855 0.0053
2024-05-14 2022-09-30 13F/A-1 GUARDANT HEALTH CMN 40131M109 1,145,719 -46,974 -3.94 62 27.08 0.0156
2022-11-14 2022-09-30 13F GUARDANT HEALTH CMN 40131M109 1,145,719 -46,974 61,674 0.0143
2024-05-14 2022-06-30 13F/A-2 GUARDANT HEALTH CMN 40131M109 1,192,693 -504,253 -29.72 48 -99.96 0.0120
2022-08-18 2022-06-30 13F/A-1 GUARDANT HEALTH CMN 40131M109 1,192,693 -504,253 48,114 0.0109
2022-08-15 2022-06-30 13F GUARDANT HEALTH CMN 40131M109 1,192,693 -504,253 48,114 0.0109
2022-05-16 2022-03-31 13F GUARDANT HEALTH CMN 40131M109 1,696,946 -55,877 -3.19 112,406 -35.88 0.0236
2022-02-17 2021-12-31 13F/A-1 GUARDANT HEALTH CMN 40131M109 1,752,823 145,296 9.04 175,318 -12.76 0.0348
2022-02-14 2021-12-31 13F GUARDANT HEALTH CMN 40131M109 1,752,823 145,296 175,318 0.0101
2022-01-20 2021-09-30 13F/A-1 GUARDANT HEALTH CMN 40131M109 1,607,527 9,783 0.61 200,957 1.28 0.0426
2021-11-10 2021-09-30 13F GUARDANT HEALTH CMN 40131M109 1,607,527 9,783 200,957 0.0425
2021-08-13 2021-06-30 13F GUARDANT HEALTH CMN 40131M109 1,597,744 210,594 15.18 198,424 -6.29 0.0445
2021-05-17 2021-03-31 13F GUARDANT HEALTH CMN 40131M109 1,387,150 84,285 6.47 211,749 26.11 0.0534
2021-02-12 2020-12-31 13F GUARDANT HEALTH CMN 40131M109 1,302,865 131,709 11.25 167,913 28.26 0.0432
2020-11-13 2020-09-30 13F GUARDANT HEALTH CMN 40131M109 1,171,156 495,996 73.46 130,912 139.00 0.0372
2020-08-12 2020-06-30 13F GUARDANT HEALTH CMN 40131M109 675,160 62,414 10.19 54,776 28.44 0.0166
2020-05-15 2020-03-31 13F GUARDANT HEALTH CMN 40131M109 612,746 59,321 10.72 42,647 -1.38 0.0150
2020-02-14 2019-12-31 13F GUARDANT HEALTH CMN 40131M109 553,425 85,591 18.30 43,244 44.81 0.0110
2019-11-14 2019-09-30 13F GUARDANT HEALTH CMN 40131M109 467,834 11,177 2.45 29,862 -24.25 0.0086
2019-08-14 2019-06-30 13F GUARDANT HEALTH CMN 40131M109 456,657 232,397 103.63 39,424 129.20 0.0113
2019-05-15 2019-03-31 13F GUARDANT HEALTH CMN 40131M109 224,260 -77,488 -25.68 17,201 51.64 0.0052
2019-02-14 2018-12-31 13F GUARDANT HEALTH CMN 40131M109 301,748 301,748 11,343 0.0036
Disclosed Call Options
File
Date
Effective
Date
Form Security Class ID Opt Avg Share
Price
Shares ΔShares
(%)
Value
(x1000)
ΔValue
(%)
Prior Allocation
(%)
Allocation
(%)
ΔAllocation
(%)
Cost Basis
(x1000)
Profit
(x1000)
Return
(%)
2024-05-14 2022-12-31 13F/A GUARDANT HEALTH CMN Call 0 -100.00 0 n/a n/a n/a
2023-02-13 2022-12-31 13F GUARDANT HEALTH CMN Call 0 0 n/a n/a n/a
2024-05-14 2022-09-30 13F/A GUARDANT HEALTH CMN Call 10,000 1 n/a n/a n/a
2022-11-14 2022-09-30 13F GUARDANT HEALTH CMN Call 10,000 538 n/a n/a n/a
2022-05-16 2022-03-31 13F GUARDANT HEALTH CMN Call 0 -100.00 0 -100.00 n/a n/a n/a
2022-02-17 2021-12-31 13F/A GUARDANT HEALTH CMN Call 4,200 0.00 420 -20.00 n/a n/a n/a
2022-02-14 2021-12-31 13F GUARDANT HEALTH CMN Call 4,200 420 n/a n/a n/a
2022-01-20 2021-09-30 13F/A GUARDANT HEALTH CMN Call 4,200 525 n/a n/a n/a
2021-11-10 2021-09-30 13F GUARDANT HEALTH CMN Call 4,200 525 n/a n/a n/a
2019-11-14 2019-09-30 13F GUARDANT HEALTH CMN Call 0 -100.00 0 -100.00 n/a n/a n/a
2019-08-14 2019-06-30 13F GUARDANT HEALTH CMN Call 10,400 0.00 898 12.53 n/a n/a n/a
2019-05-15 2019-03-31 13F GUARDANT HEALTH CMN Call 10,400 798 n/a n/a n/a
Disclosed Put Options
File
Date
Effective
Date
Form Security Class ID Opt Avg Share Price Shares ΔShares
(%)
Value
(x1000)
ΔValue
(%)
Prior Allocation
(%)
Allocation
(%)
ΔAllocation
(%)
Cost Basis
(x1000)
Profit
(x1000)
Return
(%)
2020-05-15 2020-03-31 13F GUARDANT HEALTH CMN Put 0 -100.00 0 -100.00 n/a n/a n/a
2020-02-14 2019-12-31 13F GUARDANT HEALTH CMN Put 78,700 -55.96 6,150 -46.08 n/a n/a n/a
2019-11-14 2019-09-30 13F GUARDANT HEALTH CMN Put 178,700 -7.07 11,406 -31.29 n/a n/a n/a
2019-08-14 2019-06-30 13F GUARDANT HEALTH CMN Put 192,300 612.22 16,601 701.59 n/a n/a n/a
2019-05-15 2019-03-31 13F GUARDANT HEALTH CMN Put 27,000 2,071 n/a n/a n/a
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.