Guardant Health, Inc.
DE ˙ DB ˙ US40131M1099
111,48 € ↑2,18 (1,99%)
2026-06-05
DEL PRIS
SecurityDE:5GH / Guardant Health, Inc.
InstitutionAmeriprise Financial Inc
Latest Disclosed Ownership1,414,886 shares
Latest Disclosed Value $ 130,692,879
Ameriprise Financial Inc ownership in 5GH / Guardant Health, Inc.

On May 15, 2026 - Ameriprise Financial Inc filed a 13F-HR form disclosing ownership of 1,414,886 shares of Guardant Health, Inc. (DE:5GH) valued at $106,597,511 USD as of March 31, 2026. The entity filed a previous 13F-HR on February 17, 2026 disclosing 762,595 shares of Guardant Health, Inc.. This represents a change in shares of 85.54% during the quarter. The current value of the position is $157,731,491 USD.

Ameriprise Financial Inc has a history of taking positions in derivatives of the underlying security (5GH) in the form of stock options.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Institutional Put/Call Ratios
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In addition to reporting standard equity and debt issues, institutions with more than 100MM assets under management must also disclose their put and call option holdings. Since put options generally indicate negative sentiment, and call options indicate positive sentiment, we can get a sense of the overall institutional sentiment by plotting the ratio of puts to calls. The chart to the right plots the historical put/call ratio for this instrument.

Using Put/Call Ratio as an indicator of investor sentiment overcomes one of the key deficiencies of using total institutional ownership, which is that a significant amount of assets under management are invested passively to track indices. Passively-managed funds do not typically buy options, so the put/call ratio indicator more closely tracks the sentiment of actively-managed funds.

DE:5GH / Guardant Health, Inc. Historical Put/Call Ratio
Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F GUARDANT HEALTH COM 40131M109 1,414,886 652,291 85.54 130,693 67.79 0.0056
2026-02-17 2025-12-31 13F GUARDANT HEALTH COM 40131M109 762,595 455,114 148.01 77,890 305.40 0.0176
2025-11-14 2025-09-30 13F GUARDANT HEALTH COM 40131M109 307,481 -187,391 -37.87 19,214 -25.39 0.0044
2025-08-14 2025-06-30 13F GUARDANT HEALTH COM 40131M109 494,872 331,823 203.51 25,752 270.75 0.0063
2025-05-14 2025-03-31 13F GUARDANT HEALTH COM 40131M109 163,049 7,884 5.08 6,947 46.60 0.0019
2025-02-14 2024-12-31 13F GUARDANT HEALTH COM 40131M109 155,165 76,124 96.31 4,739 161.77 0.0012
2024-11-14 2024-09-30 13F GUARDANT HEALTH COM 40131M109 79,041 7,012 9.73 1,810 -12.98 0.0005
2024-08-14 2024-06-30 13F GUARDANT HEALTH COM 40131M109 72,029 48,187 202.11 2,080 323.63 0.0006
2024-05-15 2024-03-31 13F GUARDANT HEALTH COM 40131M109 23,842 -458,154 -95.05 492 -96.23 0.0001
2024-02-14 2023-12-31 13F GUARDANT HEALTH COM 40131M109 481,996 62,993 15.03 13,038 4.98 0.0039
2023-11-14 2023-09-30 13F GUARDANT HEALTH COM 40131M109 419,003 32,364 8.37 12,419 -10.27 0.0041
2023-08-14 2023-06-30 13F GUARDANT HEALTH COM 40131M109 386,639 386,639 13,842 0.0043
2023-02-14 2022-12-31 13F GUARDANT HEALTH COM 40131M109 0 -9,917 -100.00 0 -100.00
2022-11-14 2022-09-30 13F GUARDANT HEALTH COM 40131M109 9,917 101 1.03 534 34.85 0.0002
2022-08-15 2022-06-30 13F GUARDANT HEALTH COM 40131M109 9,816 4,787 95.19 396 18.92 0.0001
2022-05-16 2022-03-31 13F GUARDANT HEALTH COM 40131M109 5,029 -3,797 -43.02 333 -62.29 0.0001
2022-02-14 2021-12-31 13F GUARDANT HEALTH COM 40131M109 8,826 1,987 29.05 883 3.27 0.0002
2021-11-15 2021-09-30 13F GUARDANT HEALTH COM 40131M109 6,839 -13,797 -66.86 855 -66.64 0.0003
2021-08-16 2021-06-30 13F GUARDANT HEALTH COM 40131M109 20,636 -9,971 -32.58 2,563 -45.13 0.0008
2021-05-17 2021-03-31 13F GUARDANT HEALTH COM 40131M109 30,607 -14,345 -31.91 4,671 -19.37 0.0016
2021-02-12 2020-12-31 13F GUARDANT HEALTH COM 40131M109 44,952 -688,302 -93.87 5,793 -92.93 0.0021
2020-11-16 2020-09-30 13F GUARDANT HEALTH COM 40131M109 733,254 -207,756 -22.08 81,914 7.37 0.0333
2020-08-14 2020-06-30 13F GUARDANT HEALTH COM 40131M109 941,010 -361,541 -27.76 76,289 -15.82 0.0327
2020-05-15 2020-03-31 13F GUARDANT HEALTH COM 40131M109 1,302,551 -130,687 -9.12 90,628 -19.03 0.0476
2020-02-14 2019-12-31 13F GUARDANT HEALTH COM 40131M109 1,433,238 97,936 7.33 111,927 31.32 0.0465
2019-11-14 2019-09-30 13F GUARDANT HEALTH COM 40131M109 1,335,302 35,730 2.75 85,233 -24.03 0.0382
2019-08-14 2019-06-30 13F GUARDANT HEALTH COM 40131M109 1,299,572 747,385 135.35 112,186 164.93 0.0503
2019-05-15 2019-03-31 13F GUARDANT HEALTH COM 40131M109 552,187 464,153 527.24 42,345 1,179.69 0.0195
2019-02-14 2018-12-31 13F GUARDANT HEALTH COM 40131M109 88,034 88,034 3,309 0.0017
Disclosed Put Options
File
Date
Effective
Date
Form Security Class ID Opt Avg Share Price Shares ΔShares
(%)
Value
(x1000)
ΔValue
(%)
Prior Allocation
(%)
Allocation
(%)
ΔAllocation
(%)
Cost Basis
(x1000)
Profit
(x1000)
Return
(%)
2026-05-15 2026-03-31 13F GUARDANT HEALTH OPT Put 46,500 4,295 n/a n/a n/a
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.