Krystal Biotech, Inc.
DE ˙ DB ˙ US5011471027
257,90 € ↓ -1,10 (-0,42%)
2026-06-04
DEL PRIS
SecurityDE:4KB / Krystal Biotech, Inc.
InstitutionMorgan Stanley
Latest Disclosed Ownership209,082 shares
Latest Disclosed Value $ 54,010,448
Morgan Stanley reports 5.60% decrease in ownership of 4KB / Krystal Biotech, Inc.

On May 15, 2026 - Morgan Stanley filed a 13F-HR form disclosing ownership of 209,082 shares of Krystal Biotech, Inc. (DE:4KB) valued at $44,994,446 USD as of March 31, 2026. The entity filed a previous 13F-HR/A on May 27, 2026 disclosing 221,481 shares of Krystal Biotech, Inc.. This represents a change in shares of -5.60% during the quarter. The current value of the position is $53,922,248 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date		 Effective
Date		Form Security Class ID Avg Price
Paid (Est)		 Reported
Shares		 ΔShares ΔShares
(%)		 Reported
Value
(x1000)		 ΔValue
(%)		 Alloc
(%)		 ΔAlloc ΔAlloc (%) Cost Basis
(x1000)		 Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F KRYSTAL BIOTECH COM 501147102 209,082 -12,399 -5.60 54,010 -1.09 0.0033
2026-05-27 2025-12-31 13F/A-1 KRYSTAL BIOTECH COM 501147102 221,481 -13,097 -5.58 54,605 31.86 0.0033
2026-02-13 2025-12-31 13F KRYSTAL BIOTECH COM 501147102 221,481 -13,097 54,605 0.0033
2026-05-27 2025-09-30 13F/A-1 KRYSTAL BIOTECH COM 501147102 234,578 157 0.07 41,410 28.51 0.0025
2025-11-14 2025-09-30 13F KRYSTAL BIOTECH COM 501147102 234,578 157 41,410 0.0025
2025-08-15 2025-06-30 13F KRYSTAL BIOTECH COM 501147102 234,421 -63,784 -21.39 32,224 -40.07 0.0021
2025-05-15 2025-03-31 13F KRYSTAL BIOTECH COM 501147102 298,205 41,930 16.36 53,767 33.92 0.0038
2025-05-15 2024-12-31 13F/A-1 KRYSTAL BIOTECH COM 501147102 256,275 -19,529 -7.08 40,148 -20.03 0.0028
2025-02-14 2024-12-31 13F KRYSTAL BIOTECH COM 501147102 256,275 -19,529 40,148 0.0028
2025-05-14 2024-09-30 13F/A-2 KRYSTAL BIOTECH COM 501147102 275,804 -42,523 -13.36 50,205 -14.12 0.0036
2025-02-14 2024-09-30 13F/A-1 KRYSTAL BIOTECH COM 501147102 275,804 -42,523 50,205 0.0036
2024-11-14 2024-09-30 13F KRYSTAL BIOTECH COM 501147102 275,804 -42,523 50,205 0.0004
2025-05-14 2024-06-30 13F/A-2 KRYSTAL BIOTECH COM 501147102 318,327 99,498 45.47 58,458 50.14 0.0045
2024-10-17 2024-06-30 13F/A-1 KRYSTAL BIOTECH COM 501147102 318,327 99,498 58,458 0.0045
2024-08-14 2024-06-30 13F KRYSTAL BIOTECH COM 501147102 318,327 99,498 58,458 0.0045
2024-10-17 2024-03-31 13F/A-2 KRYSTAL BIOTECH COM 501147102 218,829 -100,892 -31.56 38,936 -1.84 0.0031
2024-08-16 2024-03-31 13F/A-1 KRYSTAL BIOTECH COM 501147102 218,829 -100,892 38,936 0.0004
2024-05-15 2024-03-31 13F KRYSTAL BIOTECH COM 501147102 218,829 -100,892 38,936 0.0031
2024-08-16 2023-12-31 13F/A-1 KRYSTAL BIOTECH COM 501147102 319,721 31,169 10.80 39,665 18.50 0.0035
2024-02-13 2023-12-31 13F KRYSTAL BIOTECH COM 501147102 319,721 31,169 39,665 0.0035
2023-11-15 2023-09-30 13F KRYSTAL BIOTECH COM 501147102 288,552 13,725 4.99 33,472 3.74 0.0034
2023-08-14 2023-06-30 13F KRYSTAL BIOTECH COM 501147102 274,827 148,002 116.70 32,265 217.78 0.0032
2023-05-15 2023-03-31 13F KRYSTAL BIOTECH COM 501147102 126,825 60,774 92.01 10,154 94.06 0.0011
2023-02-14 2022-12-31 13F KRYSTAL BIOTECH COM 501147102 66,051 18,738 39.60 5,233 58.59 0.0006
2022-11-14 2022-09-30 13F KRYSTAL BIOTECH COM 501147102 47,313 -32,041 -40.38 3,299 -36.67 0.0004
2022-10-27 2022-06-30 13F/A-1 KRYSTAL BIOTECH COM 501147102 79,354 7,374 10.24 5,209 8.79 0.0007
2022-08-15 2022-06-30 13F KRYSTAL BIOTECH COM 501147102 79,354 7,374 5,209 0.0001
2022-10-27 2022-03-31 13F/A-1 KRYSTAL BIOTECH COM 501147102 71,980 -39,018 -35.15 4,788 -38.32 0.0006
2022-05-13 2022-03-31 13F KRYSTAL BIOTECH COM 501147102 71,980 -39,018 4,788 0.0006
2022-02-14 2021-12-31 13F KRYSTAL BIOTECH COM 501147102 110,998 77,764 233.99 7,763 347.18 0.0010
2021-11-15 2021-09-30 13F KRYSTAL BIOTECH COM 501147102 33,234 -10,217 -23.51 1,736 -41.23 0.0002
2021-08-23 2021-06-30 13F/A-1 KRYSTAL BIOTECH COM 501147102 43,451 31,745 271.19 2,954 227.86 0.0004
2021-08-16 2021-06-30 13F KRYSTAL BIOTECH COM 501147102 43,451 31,745 2,954 0.0001
2021-05-17 2021-03-31 13F KRYSTAL BIOTECH COM 501147102 11,706 665 6.02 901 35.90 0.0001
2021-02-16 2020-12-31 13F KRYSTAL BIOTECH COM 501147102 11,041 7,238 190.32 663 306.75 0.0001
2020-11-13 2020-09-30 13F KRYSTAL BIOTECH COM 501147102 3,803 -1,839 -32.59 163 -30.34 0.0000
2020-08-14 2020-06-30 13F KRYSTAL BIOTECH COM 501147102 5,642 3,411 152.89 234 143.75 0.0001
2020-05-26 2020-03-31 13F/A-1 KRYSTAL BIOTECH COM 501147102 2,231 -12,960 -85.31 96 -88.59 0.0000
2020-05-15 2020-03-31 13F KRYSTAL BIOTECH COM 501147102 2,231 -12,960 96 7.3748
2020-02-14 2019-12-31 13F KRYSTAL BIOTECH COM 501147102 15,191 6,105 67.19 841 166.98 0.0002
2019-11-14 2019-09-30 13F KRYSTAL BIOTECH COM 501147102 9,086 -15,831 -63.53 315 -68.63 0.0001
2019-08-14 2019-06-30 13F KRYSTAL BIOTECH COM 501147102 24,917 23,002 1,201.15 1,004 1,493.65 0.0003
2019-05-15 2019-03-31 13F KRYSTAL BIOTECH COM 501147102 1,915 -2,085 -52.12 63 -24.10 0.0000
2019-02-14 2018-12-31 13F KRYSTAL BIOTECH COM 501147102 4,000 -1,366 -25.46 83 -11.70 0.0000
2019-04-23 2018-09-30 13F/A-2 KRYSTAL BIOTECH COM 501147102 5,366 4,170 348.66 94 422.22 0.0000
2018-11-20 2018-09-30 13F/A-1 KRYSTAL BIOTECH COM 501147102 5,366 0 94 0.0000
2018-11-14 2018-09-30 13F KRYSTAL BIOTECH COM 501147102 5,366 4,170 94
2019-04-23 2018-06-30 13F/A-1 KRYSTAL BIOTECH COM 501147102 1,196 1,196 18 0.0000
2018-08-14 2018-06-30 13F KRYSTAL BIOTECH COM 501147102 1,196 18 0.0000
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.