Schrödinger, Inc.
DE ˙ DB ˙ US80810D1037
13,34 € ↑0,99 (7,97%)
2026-06-05
DEL PRIS
SecurityDE:43Z / Schrödinger, Inc.
InstitutionTwo Sigma Advisers, Lp
Latest Disclosed Ownership506,600 shares
Latest Disclosed Value $ 9,058,008
Two Sigma Advisers, Lp reports 31.64% decrease in ownership of 43Z / Schrödinger, Inc.

On February 17, 2026 - Two Sigma Advisers, Lp filed a 13F-HR form disclosing ownership of 506,600 shares of Schrödinger, Inc. (DE:43Z) valued at $7,561,005 USD as of December 31, 2025. The entity filed a previous 13F-HR on November 14, 2025 disclosing 741,100 shares of Schrödinger, Inc.. This represents a change in shares of -31.64% during the quarter. The current value of the position is $6,760,577 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-02-17 2025-12-31 13F SCHRODINGER COM 80810D103 506,600 -234,500 -31.64 9,058 -39.07 0.0176
2025-11-14 2025-09-30 13F SCHRODINGER COM 80810D103 741,100 18,000 2.49 14,866 2.19 0.0298
2025-08-14 2025-06-30 13F SCHRODINGER COM 80810D103 723,100 596,800 472.53 14,549 483.55 0.0298
2025-05-15 2025-03-31 13F SCHRODINGER COM 80810D103 126,300 101,800 415.51 2,493 428.18 0.0056
2025-02-14 2024-12-31 13F SCHRODINGER COM 80810D103 24,500 24,500 473 0.0011
2023-08-14 2023-06-30 13F SCHRODINGER COM 80810D103 0 -84,400 -100.00 0 -100.00
2023-05-15 2023-03-31 13F SCHRODINGER COM 80810D103 84,400 -65,900 -43.85 2,222 -20.90 0.0057
2023-02-14 2022-12-31 13F SCHRODINGER COM 80810D103 150,300 -12,300 -7.56 2,809 -30.85 0.0078
2022-11-14 2022-09-30 13F SCHRODINGER COM 80810D103 162,600 47,400 41.15 4,062 33.53 0.0118
2022-08-15 2022-06-30 13F SCHRODINGER COM 80810D103 115,200 -10,700 -8.50 3,042 -29.19 0.0086
2022-05-16 2022-03-31 13F SCHRODINGER COM 80810D103 125,900 -3,900 -3.00 4,296 -4.98 0.0114
2022-02-14 2021-12-31 13F SCHRODINGER COM 80810D103 129,800 94,900 271.92 4,521 136.95 0.0113
2021-11-15 2021-09-30 13F SCHRODINGER COM 80810D103 34,900 24,600 238.83 1,908 144.93 0.0049
2021-08-16 2021-06-30 13F SCHRODINGER COM 80810D103 10,300 10,300 779 0.0021
2021-05-17 2021-03-31 13F SCHRODINGER COM 80810D103 0 -77,900 -100.00 0 -100.00
2021-02-16 2020-12-31 13F SCHRODINGER COM 80810D103 77,900 -24,800 -24.15 6,168 26.42 0.0165
2020-11-16 2020-09-30 13F SCHRODINGER COM 80810D103 102,700 102,700 4,879 0.0139
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.