Spyre Therapeutics, Inc.
DE ˙ DB ˙ US00773J2024
60,00 € ↑0,50 (0,84%)
2026-06-03
DEL PRIS
SecurityDE:3920 / Spyre Therapeutics, Inc.
InstitutionCommodore Capital Lp
Latest Disclosed Ownership1,988,084 shares
Ownership 3.90%
Commodore Capital Lp ownership in 3920 / Spyre Therapeutics, Inc.

2024-11-14 - Commodore Capital Lp has filed an SC 13G/A form with the Securities and Exchange Commission (SEC) disclosing ownership of 1,988,084 shares of Spyre Therapeutics, Inc. (DE:3920). This represents 3.9 percent ownership of the company. In their previous filing dated 2024-02-14 , Commodore Capital Lp had reported owning 1,934,084 shares, indicating an increase of 2.79 percent.

Institutional Ownership: 13D/G Filings

This table shows a history of the 13D/G filings made by the investor and/or investor group. Note that the share values in this table are not directly comparable to any numbers shown in the 13F table (if any).

File
Date
Effective
Date
Form Prev
Shares
Latest
Shares
ΔShares
(Percent)
Ownership
(Percent)
ΔOwnership
(Percent)
2024-11-14 2024-11-14 13G/A 1,934,084 1,988,084 2.79 3.90 -27.78
2024-02-14 2024-02-14 13G/A 1,834,084 1,934,084 5.45 5.40 -11.48
2023-12-01 2023-12-01 13G 1,834,084 6.10

Important Note: One of the primary uses of the 13D/G filings is to evaluate the ability of a firm to control a company (ie, the "beneficial ownership"). To that end, firms are required to report not just direct holdings in companies, but indirect holdings that they control. For investment firms, these indirect holdings can include shares in funds they manage, advisory accounts, and in the case of activist campaigns, pledged votes. Therefore, share counts listed in 13D/G filings can differ significantly than share counts listed in 13F filings.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-05-15 2026-03-31 13F SPYRE THERAPEUTICS COM NEW 00773J202 1,912,380 -475,865 -19.93 96,460 23.29 5.5807
2026-02-17 2025-12-31 13F SPYRE THERAPEUTICS COM NEW 00773J202 2,388,245 400,161 20.13 78,239 134.81 5.2081
2025-11-14 2025-09-30 13F SPYRE THERAPEUTICS COM NEW 00773J202 1,988,084 0 0.00 33,320 11.96 1.6266
2025-08-14 2025-06-30 13F SPYRE THERAPEUTICS COM NEW 00773J202 1,988,084 0 0.00 29,762 -7.22 2.1007
2025-05-15 2025-03-31 13F SPYRE THERAPEUTICS COM NEW 00773J202 1,988,084 0 0.00 32,078 -30.69 2.3637
2025-02-14 2024-12-31 13F SPYRE THERAPEUTICS COM NEW 00773J202 1,988,084 0 0.00 46,283 -20.84 3.3918
2024-11-14 2024-09-30 13F SPYRE THERAPEUTICS COM NEW 00773J202 1,988,084 0 0.00 58,470 25.10 3.6537
2024-08-14 2024-06-30 13F SPYRE THERAPEUTICS COM NEW 00773J202 1,988,084 104,000 5.52 46,740 -34.60 3.1904
2024-05-15 2024-03-31 13F SPYRE THERAPEUTICS COM NEW 00773J202 1,884,084 0 0.00 71,463 76.26 4.7786
2024-02-14 2023-12-31 13F/A-1 SPYRE THERAPEUTICS COM NEW 00773J202 1,884,084 1,767,760 1,519.69 40,545 2,747.26 3.5427
2024-02-14 2023-12-31 13F SPYRE THERAPEUTICS COM NEW 00773J202 1,884,084 1,767,760 40,545 3.5080
2023-11-14 2023-09-30 13F AEGLEA BIOTHERAPEUTICS COM NEW 00773J202 116,324 116,324 1,425 0.1666
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.