Mirum Pharmaceuticals, Inc.
DE ˙ DB ˙ US6047491013
77,12 € ↑0,96 (1,26%)
2026-06-05
DEL PRIS
SecurityDE:08D / Mirum Pharmaceuticals, Inc.
InstitutionTwo Sigma Advisers, Lp
Latest Disclosed Ownership232,100 shares
Latest Disclosed Value $ 18,333,579
Two Sigma Advisers, Lp reports 16.03% decrease in ownership of 08D / Mirum Pharmaceuticals, Inc.

On February 17, 2026 - Two Sigma Advisers, Lp filed a 13F-HR form disclosing ownership of 232,100 shares of Mirum Pharmaceuticals, Inc. (DE:08D) valued at $15,434,650 USD as of December 31, 2025. The entity filed a previous 13F-HR on November 14, 2025 disclosing 276,400 shares of Mirum Pharmaceuticals, Inc.. This represents a change in shares of -16.03% during the quarter. The current value of the position is $17,899,552 USD.

Institutional Ownership: 13F and NPORT Filings

The Security and Class in the table below are shown exactly as filed by the investor. We do our best to track continuity of investments through acquisitions, and this will be reflected in the table as changes in names. In addition to descriptive data, performance of the investment is shown over time. To calculate quarterly performance, we first calculate cost basis of the shares purchased during the quarter, then use that to calculate gross profit. Quarterly return is Gross Profit / Starting Portfolio value.

Note that cost basis is calculated and stored in thousands, so small quarterly changes in shares frequently result in a cost basis of zero.

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Disclosed Equity Positions (from 13F/NPORT Filings)
File
Date
Effective
Date
Form Security Class ID Avg Price
Paid (Est)
Reported
Shares
ΔShares ΔShares
(%)
Reported
Value
(x1000)
ΔValue
(%)
Alloc
(%)
ΔAlloc ΔAlloc (%) Cost Basis
(x1000)
Unrealized
Gain/Loss
(x1000)
2026-02-17 2025-12-31 13F MIRUM PHARMACEUTICALS COM 604749101 232,100 -44,300 -16.03 18,334 -9.52 0.0356
2025-11-14 2025-09-30 13F MIRUM PHARMACEUTICALS COM 604749101 276,400 105,000 61.26 20,263 132.31 0.0405
2025-08-14 2025-06-30 13F MIRUM PHARMACEUTICALS COM 604749101 171,400 -35,200 -17.04 8,723 -6.29 0.0179
2025-05-15 2025-03-31 13F MIRUM PHARMACEUTICALS COM 604749101 206,600 32,200 18.46 9,307 29.07 0.0210
2025-02-14 2024-12-31 13F MIRUM PHARMACEUTICALS COM 604749101 174,400 -31,100 -15.13 7,211 -10.02 0.0167
2024-11-14 2024-09-30 13F MIRUM PHARMACEUTICALS COM 604749101 205,500 25,600 14.23 8,014 30.31 0.0188
2024-08-14 2024-06-30 13F MIRUM PHARMACEUTICALS COM 604749101 179,900 -17,100 -8.68 6,151 24.29 0.0137
2024-05-15 2024-03-31 13F MIRUM PHARMACEUTICALS COM 604749101 197,000 -139,300 -41.42 4,949 -50.16 0.0115
2024-02-14 2023-12-31 13F MIRUM PHARMACEUTICALS COM 604749101 336,300 -54,600 -13.97 9,928 -19.63 0.0232
2023-11-14 2023-09-30 13F MIRUM PHARMACEUTICALS COM 604749101 390,900 328,300 524.44 12,352 662.94 0.0316
2023-08-14 2023-06-30 13F MIRUM PHARMACEUTICALS COM 604749101 62,600 32,300 106.60 1,619 122.70 0.0041
2023-05-15 2023-03-31 13F MIRUM PHARMACEUTICALS COM 604749101 30,300 -49,500 -62.03 728 -53.28 0.0019
2023-02-14 2022-12-31 13F MIRUM PHARMACEUTICALS COM 604749101 79,800 -32,100 -28.69 1,556 -33.82 0.0043
2022-11-14 2022-09-30 13F MIRUM PHARMACEUTICALS COM 604749101 111,900 -46,100 -29.18 2,351 -23.54 0.0068
2022-08-15 2022-06-30 13F MIRUM PHARMACEUTICALS COM 604749101 158,000 -45,800 -22.47 3,075 -31.48 0.0087
2022-05-16 2022-03-31 13F MIRUM PHARMACEUTICALS COM 604749101 203,800 36,058 21.50 4,488 67.78 0.0119
2022-02-14 2021-12-31 13F MIRUM PHARMACEUTICALS COM 604749101 167,742 74,242 79.40 2,675 43.59 0.0067
2021-11-15 2021-09-30 13F MIRUM PHARMACEUTICALS COM 604749101 93,500 11,700 14.30 1,863 31.75 0.0048
2021-08-16 2021-06-30 13F MIRUM PHARMACEUTICALS COM 604749101 81,800 12,600 18.21 1,414 3.06 0.0037
2021-05-17 2021-03-31 13F MIRUM PHARMACEUTICALS COM 604749101 69,200 46,100 199.57 1,372 240.45 0.0038
2021-02-16 2020-12-31 13F MIRUM PHARMACEUTICALS COM 604749101 23,100 23,100 403 0.0011
Legend
Shares
The total number of shares held by the institution at the end of the reporting period (the effective date). This is provided in the filing.
Value
The total value of the shares as of the effective date. This is provided in the filing.
Avg. Share Price
The weighted average share price of the shares held by the institution. We use FIFO accounting to determine this price
Class
This is the security class as indicated by the filer. There are a variety of values for this field. Common values include "EC" = equity common, "EP" - equity preferred
Allocation (%)
The percent of the institution's portfolio that this position represents. This is provided in NPORT filings. For 13F filings, we calculate it.
Change in Allocation
The change in allocation from the prior reporting period. This is calculated as current allocation - prior allocation.
Change in Allocation (%)
The percent change in allocation from the prior reporting period. This is calculated as (current allocation - prior allocation) / prior allocation.
Cost Basis
The total cost of the shares held. This is calculated as reported shares * avg. share price
Unrealized Gain/Loss
This is the market value of the position as of the effective date minus the cost basis.