TSRO Insider Trading - TESARO, Inc.

Insideraktier

39.014.911 shares

Insider-stemningsscore

Insider Sentiment Score viser, at virksomhederne bliver købt af virksomheders insidere.

Det er resultatet af en sofistikeret, multi-faktor kvantitativ model, der identificerer virksomheder med de højeste niveauer af insider-akkumulering. Scoringsmodellen bruger en kombination af nettoantallet af insidere, der har købt de foregående 90 dage, det samlede antal aktier købt som en procentdel af float og det samlede antal aktier ejet af insidere. Tallet går fra 0 til 100, hvor højere tal indikerer et højere niveau af akkumulering for sine jævnaldrende, og 50 er gennemsnittet.

Opdateringsfrekvens: Dagligt

Se Insiders Top Picks, som giver en liste over virksomheder med den højeste insider-akkumulering.

Se Højest rangerende aktier

Officers sentiment score

Officer Sentiment Score finder virksomheder, der bliver købt af Corporate Officers.

Per definition er Corporate Officers Corporate Insiders, men i modsætning til nogle af de andre Insiders (10 % aktionærer og bestyrelsesmedlemmer), arbejder officerer for virksomheden på daglig basis, og de bruger deres egne penge, når de handler . (10 % aktionærer og bestyrelsesmedlemmer er ofte fondsforvaltere, der administrerer andres penge.) Som sådan er insiderhandler foretaget af embedsmænd meget mere betydningsfulde og bør behandles passende.

Ligesom Insider Sentiment Score er Officer Sentiment Score resultatet af en sofistikeret, multi-faktor kvantitativ model, der identificerer virksomheder med de højeste niveauer af officerakkumulering.

Opdateringsfrekvens: Dagligt

Se Insiders Top Picks, som giver en liste over virksomheder med højeste insider-stemning.

Se Højest rangerende aktier

Nøgle Insider Metrics

Dette kort viser, hvordan virksomheden rangerer langs forskellige insider-metrics. Percentilrangen viser, hvordan denne virksomhed sammenligner sig med andre virksomheder på de amerikanske markeder. Højere placeringer er tegn på bedre situationer.

For eksempel er det generelt accepteret, at insider-køb er en positiv indikator, så virksomheder med flere insider-køb vil rangere højere end virksomheder med mindre insider-køb (eller endda insider-salg).

Netto antal insidere, der køber (rang)

N/A

Netto antal insidere, der køber, er det samlede antal insiders, der køber minus det samlede antal insiders, der har solgt inden for de sidste 90 dage. Percentilrangen vises her (spænder fra 0 til 100%).

Procent af float købt af insidere (rangering)

N/A

Procent af float købt af insidere er det samlede antal aktier købt af insidere minus det samlede antal aktier solgt af insidere inden for de sidste 90 dage, divideret med den samlede float og ganget med 100.

Insiderhandelsdiagram

TESARO, Inc. insiderhandler er vist i følgende diagram. Insidere er embedsmænd, direktører eller betydelige investorer i en virksomhed. Generelt er det generelt ulovligt for insidere at foretage handler i deres virksomheder baseret på væsentlige, ikke-offentlige oplysninger. Dette betyder ikke, at det er ulovligt for dem at handle i deres egne virksomheder. De skal dog rapportere alle handler til SEC via en formular 4.

Insiderliste og lønsomhedsmålinger

Denne tabel viser listen over kendte insidere og genereres automatisk fra arkiveringer, der er videregivet til SEC. Ud over navnene, den seneste titel og direktør, officer eller 10 % ejerbetegnelse giver vi de seneste offentliggjorte besiddelser. Derudover giver vi, når det er muligt, den historiske handelspræstation for insideren. Den historiske handelspræstation er et vægtet gennemsnit af præstationen af faktiske købstransaktioner på det åbne marked foretaget af insideren. For mere information om, hvordan dette beregnes, se dette YouTube-webinar.

See our leaderboard of most profitable insider traders.

Insider	Gennemsnitlig fortjeneste (%)	Aktier Ejet	Dele Justeret

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Track Records af insiderkøb - Kortsigtet profitanalyse

I dette afsnit analyserer vi rentabiliteten af ethvert uplanlagt insiderkøb i åbent marked foretaget i TSRO / TESARO, Inc.. Denne analyse hjælper med at forstå, om insideren konsekvent genererer unormale afkast og er værd at følge. Denne analyse er for et år efter hver handel, og resultaterne er teoretiske .

Følgende tabel viser de seneste køb på det åbne marked, der ikke var en del af en automatisk handelsplan.

Handelsdato	Insider	Rapporteret Aktier	Rapporteret Pris	Justeret Aktier	Justeret Pris	Omkostningsgrundlag	dage til Maks
2018-03-06	NEW ENTERPRISE ASSOCIATES 13 LP	12.634	59,8154	12.634	59,8154	755.708	318
2018-03-06	BASKETT FOREST	3.159	59,8154	3.159	59,8154	188.957
2018-03-05	NEW ENTERPRISE ASSOCIATES 13 LP	17.248	59,7642	17.248	59,7642	1.030.813
2018-03-05	NEW ENTERPRISE ASSOCIATES 13 LP	1.600	59,1460	1.600	59,1460	94.634
2018-03-05	NEW ENTERPRISE ASSOCIATES 13 LP	30.321	58,2815	30.321	58,2815	1.767.153
2018-03-05	BASKETT FOREST	4.311	59,7642	4.311	59,7642	257.643
2018-03-05	BASKETT FOREST	400	59,1460	400	59,1460	23.658
2018-03-05	BASKETT FOREST	7.557	58,2815	7.557	58,2815	440.433
2018-03-02	NEW ENTERPRISE ASSOCIATES 13 LP	17.859	57,3444	17.859	57,3444	1.024.114

Justeret pris er den split-justerede pris. Adjusted Shares er de split-justerede aktier.

Track Records af insidersalg - Kortsigtet tabsanalyse

I dette afsnit analyserer vi den kortsigtede undgåelse af tab af ethvert uplanlagt insidersalg på åbent marked, der foretages i TSRO / TESARO, Inc.. Et konsekvent mønster af tabsforebyggelse kan tyde på, at fremtidige salgstransaktioner kan forudsige prisfald. Denne analyse er for et år efter hver handel, og resultaterne er teoretiske .

Følgende tabel viser de seneste salg på det åbne marked, der ikke var en del af en automatisk handelsplan.

Handelsdato	Insider	Rapporteret Aktier	Rapporteret Pris	Justeret Aktier	Justeret Pris	Omkostningsgrundlag	dage til Min
2018-08-07	ORONSKY ARNOLD L	10.000	26,7721	10.000	26,7721	267.721	94
2018-03-08	Oliveira Orlando	3.000	69,8800	3.000	69,8800	209.640
2017-12-04	Huber Martin H. Jr.	829	85,2400	829	85,2400	70.664
2017-09-05	Oliveira Orlando	71	132,6600	71	132,6600	9.419
2017-04-03	Huber Martin H. Jr.	829	153,0200	829	153,0200	126.854
2017-01-03	Huber Martin H. Jr.	190	136,2600	190	136,2600	25.889
2016-11-02	Huber Martin H. Jr.	327	121,2900	327	121,2900	39.662
2016-08-30	Hanke Jeffrey H.	29.166	86,0400	29.166	86,0400	2.509.443
2015-06-15	Viswanathan Ravi	553	54,9594	553	54,9594	30.393

Justeret pris er den split-justerede pris. Adjusted Shares er de split-justerede aktier.

Transaktionshistorik

Klik på linkikonet for at se den fulde transaktionshistorik. Transaktioner, der rapporteres som en del af en automatisk handelsplan 10b5-1, vil have et X i kolonnen markeret 10b-5.

Fil Dato	Handle Dato	Form	Insider	Ticker	Sikkerhedstitel	Kode	Direkte	Dyrke motion Pris	Enhed Pris	Enheder Ændret	Værdi Ændret (1K)	Tilbage Muligheder	Tilbage Aktier
2019-01-24	2019-01-22	4	SEIDENBERG BETH C	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	46,89		-7.209		0
2019-01-24	2019-01-22	4	SEIDENBERG BETH C	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	149,22		-12.000		0
2019-01-24	2019-01-22	4	SEIDENBERG BETH C	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	47,27		-12.000		0
2019-01-24	2019-01-22	4	SEIDENBERG BETH C	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	46,22		-10.000		0
2019-01-24	2019-01-22	4	SEIDENBERG BETH C	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	60,77		-10.000		0
2019-01-24	2019-01-22	4	SEIDENBERG BETH C	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	26,36		-10.000		0
2019-01-24	2019-01-22	4	SEIDENBERG BETH C	TSRO	Director Restricted Stock Units	D - Sale to Issuer	D			-4.052		0
2019-01-24	2019-01-22	4	SEIDENBERG BETH C By Michael J. Seidenberg Irrevocable Trust	TSRO	Common Stock	U - Other	I		75,0000	-868	-65		0
2019-01-24	2019-01-22	4	SEIDENBERG BETH C By Michael J. Seidenberg Irrevocable Trust	TSRO	Common Stock	U - Other	I		75,0000	-868	-65		0
2019-01-24	2019-01-22	4	SEIDENBERG BETH C See footnotes	TSRO	Common Stock	U - Other	I		75,0000	-10.998	-825		0
2019-01-24	2019-01-22	4	SEIDENBERG BETH C See footnotes	TSRO	Common Stock	U - Other	I		75,0000	-168.755	-12.657		0
2019-01-24	2019-01-22	4	SEIDENBERG BETH C See footnotes	TSRO	Common Stock	U - Other	I		75,0000	-1.994.768	-149.608		0
2019-01-24	2019-01-22	4	SEIDENBERG BETH C	TSRO	Common Stock	U - Other	D		75,0000	-45.907	-3.443		0
2019-01-22	2019-01-22	4	MOTT DAVID M	TSRO	Director Nonqualified Stock Option (Right to Buy)	D - Sale to Issuer	D	46,89		-7.290		0
2019-01-22	2019-01-22	4	MOTT DAVID M	TSRO	Director Nonqualified Stock Option (Right to Buy)	D - Sale to Issuer	D	47,27		-12.000		0
2019-01-22	2019-01-22	4	MOTT DAVID M	TSRO	Director Nonqualified Stock Option (Right to Buy)	D - Sale to Issuer	D	149,22		-12.000		0
2019-01-22	2019-01-22	4	MOTT DAVID M	TSRO	Director Nonqualified Stock Option (Right to Buy)	D - Sale to Issuer	D	60,77		-10.000		0
2019-01-22	2019-01-22	4	MOTT DAVID M	TSRO	Director Nonqualified Stock Option (Right to Buy)	D - Sale to Issuer	D	46,22		-10.000		0
2019-01-22	2019-01-22	4	MOTT DAVID M	TSRO	Director Nonqualified Stock Option (Right to Buy)	D - Sale to Issuer	D	26,36		-10.000		0
2019-01-22	2019-01-22	4	MOTT DAVID M	TSRO	Director Restricted Stock Units	D - Sale to Issuer	D			-4.052		0
2019-01-22	2019-01-22	4	MOTT DAVID M See Note 4	TSRO	Common Stock	U - Other	I		75,0000	-1.333	-100		0
2019-01-22	2019-01-22	4	MOTT DAVID M See Note 3	TSRO	Common Stock	U - Other	I		75,0000	-739.517	-55.464		0
2019-01-22	2019-01-22	4	MOTT DAVID M See Note 2	TSRO	Common Stock	U - Other	I		75,0000	-9.681.038	-726.078		0
2019-01-22	2019-01-22	4	MOTT DAVID M	TSRO	Common Stock	U - Other	D		75,0000	-15.362	-1.152		0
2019-01-22	2019-01-22	4	NEW ENTERPRISE ASSOCIATES 13 LP See Note 2	TSRO	Common Stock	U - Other	I		75,0000	-9.681.038	-726.078		0
2019-01-22	2019-01-22	4	BARRIS PETER J See Note 4	TSRO	Common Stock	U - Other	I		75,0000	-767	-58		0
2019-01-22	2019-01-22	4	BARRIS PETER J See Note 5	TSRO	Common Stock	U - Other	I		75,0000	-767	-58		0
2019-01-22	2019-01-22	4	BARRIS PETER J See Note 3	TSRO	Common Stock	U - Other	I		75,0000	-739.517	-55.464		0
2019-01-22	2019-01-22	4	BARRIS PETER J See Note 2	TSRO	Common Stock	U - Other	I		75,0000	-9.681.038	-726.078		0
2019-01-22	2019-01-22	4	BASKETT FOREST See Note 3	TSRO	Common Stock	U - Other	I		75,0000	-739.517	-55.464		0
2019-01-22	2019-01-22	4	BASKETT FOREST See Note 2	TSRO	Common Stock	U - Other	I		75,0000	-9.681.038	-726.078		0
2019-01-22	2019-01-22	4	KERINS PATRICK J	TSRO	Common Stock	U - Other	D		75,0000	-1.333	-100		0
2019-01-22	2019-01-22	4	KERINS PATRICK J See Note 2	TSRO	Common Stock	U - Other	I		75,0000	-9.681.038	-726.078		0
2019-01-22	2019-01-22	4	SANDELL SCOTT D See Note 3	TSRO	Common Stock	U - Other	I		75,0000	-739.517	-55.464		0
2019-01-22	2019-01-22	4	SANDELL SCOTT D See Note 2	TSRO	Common Stock	U - Other	I		75,0000	-9.681.038	-726.078		0
2019-01-22	2019-01-22	4	Alleva Lawrence M	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	46,89		-7.209		0
2019-01-22	2019-01-22	4	Alleva Lawrence M	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	47,27		-12.000		0
2019-01-22	2019-01-22	4	Alleva Lawrence M	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	149,22		-12.000		0
2019-01-22	2019-01-22	4	Alleva Lawrence M	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	60,77		-10.000		0
2019-01-22	2019-01-22	4	Alleva Lawrence M	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	46,22		-10.000		0
2019-01-22	2019-01-22	4	Alleva Lawrence M	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	26,36		-10.000		0
2019-01-22	2019-01-22	4	Alleva Lawrence M	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	6,62		-21.428		0
2019-01-22	2019-01-22	4	Alleva Lawrence M	TSRO	Director Restricted Stock Units	D - Sale to Issuer	D			-4.052		0
2019-01-22	2019-01-22	4	Alleva Lawrence M	TSRO	Common Stock	U - Other	D		75,0000	-29.902	-2.243		0
2019-01-22	2019-01-22	4	Armitage James O	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	46,89		-7.209		0
2019-01-22	2019-01-22	4	Armitage James O	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	47,27		-12.000		0
2019-01-22	2019-01-22	4	Armitage James O	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	149,22		-12.000		0
2019-01-22	2019-01-22	4	Armitage James O	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	60,77		-10.000		0
2019-01-22	2019-01-22	4	Armitage James O	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	46,22		-25.000		0
2019-01-22	2019-01-22	4	Armitage James O	TSRO	Director Restricted Stock Units	D - Sale to Issuer	D			-4.052		0
2019-01-22	2019-01-22	4	Armitage James O By The Nancy E. Armitage Revocable Living Trust	TSRO	Common Stock	U - Other	I		75,0000	-1.500	-112		0
2019-01-22	2019-01-22	4	Bogle Grant C.	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	55,84		-31.954		0
2019-01-22	2019-01-22	4	Bogle Grant C.	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	178,95		-10.782		0
2019-01-22	2019-01-22	4	Bogle Grant C.	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	43,39		-32.083		0
2019-01-22	2019-01-22	4	Bogle Grant C.	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	59,71		-66.667		0
2019-01-22	2019-01-22	4	Bogle Grant C.	TSRO	Restricted Stock Units	D - Sale to Issuer	D			-18.182		0
2019-01-22	2019-01-22	4	Bogle Grant C.	TSRO	Restricted Stock Units	D - Sale to Issuer	D			-4.447		0
2019-01-22	2019-01-22	4	Bogle Grant C.	TSRO	Restricted Stock Units	D - Sale to Issuer	D			-8.750		0
2019-01-22	2019-01-22	4	Bogle Grant C.	TSRO	Common Stock	U - Other	D		75,0000	-4.977	-373		0
2019-01-22	2019-01-22	4	COLLIER EARL M JR	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	46,89		-7.209		0
2019-01-22	2019-01-22	4	COLLIER EARL M JR	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	47,27		-12.000		0
2019-01-22	2019-01-22	4	COLLIER EARL M JR	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	149,22		-12.000		0
2019-01-22	2019-01-22	4	COLLIER EARL M JR	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	60,77		-10.000		0
2019-01-22	2019-01-22	4	COLLIER EARL M JR	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	26,36		-25.000		0
2019-01-22	2019-01-22	4	COLLIER EARL M JR	TSRO	Director Restricted Stock Units	D - Sale to Issuer	D			-4.052		0
2019-01-22	2019-01-22	4	COLLIER EARL M JR	TSRO	Common Stock	U - Other	D		75,0000	-2.090	-157		0
2019-01-22	2019-01-22	4	COVINO GREGORY F	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	40,55		-29.509		0
2019-01-22	2019-01-22	4	COVINO GREGORY F	TSRO	Restricted Stock Units	D - Sale to Issuer	D			-17.174		0
2019-01-22	2019-01-22	4	COVINO GREGORY F	TSRO	Restricted Stock Units	D - Sale to Issuer	D			-1.525		0
2019-01-22	2019-01-22	4	COVINO GREGORY F	TSRO	Common Stock	U - Other	D		75,0000	-2.156	-162		0
2019-01-22	2019-01-22	4	Farmer Joseph L	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	55,84		-31.954		0
2019-01-22	2019-01-22	4	Farmer Joseph L	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	178,95		-10.782		0
2019-01-22	2019-01-22	4	Farmer Joseph L	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	43,39		-35.000		0
2019-01-22	2019-01-22	4	Farmer Joseph L	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	57,66		-75.000		0
2019-01-22	2019-01-22	4	Farmer Joseph L	TSRO	Restricted Stock Units	D - Sale to Issuer	D			-18.182		0
2019-01-22	2019-01-22	4	Farmer Joseph L	TSRO	Restricted Stock Units	D - Sale to Issuer	D			-4.447		0
2019-01-22	2019-01-22	4	Farmer Joseph L	TSRO	Restricted Stock Units	D - Sale to Issuer	D			-1.250		0
2019-01-22	2019-01-22	4	Farmer Joseph L	TSRO	Restricted Stock Units	D - Sale to Issuer	D			-8.750		0
2019-01-22	2019-01-22	4	Farmer Joseph L	TSRO	Common Stock	U - Other	D		75,0000	-9.367	-703		0
2019-01-22	2019-01-22	4	Hedley Mary Lynne	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	55,84		-71.896		0
2019-01-22	2019-01-22	4	Hedley Mary Lynne	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	178,95		-20.216		0
2019-01-22	2019-01-22	4	Hedley Mary Lynne	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	43,39		-80.000		0
2019-01-22	2019-01-22	4	Hedley Mary Lynne	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	55,11		-115.000		0
2019-01-22	2019-01-22	4	Hedley Mary Lynne	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	33,74		-105.000		0
2019-01-22	2019-01-22	4	Hedley Mary Lynne	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	24,18		-175.000		0
2019-01-22	2019-01-22	4	Hedley Mary Lynne	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	6,62		-319.467		0
2019-01-22	2019-01-22	4	Hedley Mary Lynne	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	1,33		-285.714		0
2019-01-22	2019-01-22	4	Hedley Mary Lynne	TSRO	Restricted Stock Units	D - Sale to Issuer	D			-40.909		0
2019-01-22	2019-01-22	4	Hedley Mary Lynne	TSRO	Restricted Stock Units	D - Sale to Issuer	D			-8.339		0
2019-01-22	2019-01-22	4	Hedley Mary Lynne	TSRO	Restricted Stock Units	D - Sale to Issuer	D			-20.000		0
2019-01-22	2019-01-22	4	Hedley Mary Lynne	TSRO	Common Stock	U - Other	I		75,0000	-563.569	-42.268		0
2019-01-22	2019-01-22	4	Hedley Mary Lynne	TSRO	Common Stock	U - Other	D		75,0000	-26.816	-2.011		0
2019-01-22	2019-01-22	4	Huber Martin H. Jr.	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	55,84		-39.942		0
2019-01-22	2019-01-22	4	Huber Martin H. Jr.	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	178,95		-10.782		0
2019-01-22	2019-01-22	4	Huber Martin H. Jr.	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	43,39		-35.000		0
2019-01-22	2019-01-22	4	Huber Martin H. Jr.	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	55,14		-75.000		0
2019-01-22	2019-01-22	4	Huber Martin H. Jr.	TSRO	Restricted Stock Units	D - Sale to Issuer	D			-22.727		0
2019-01-22	2019-01-22	4	Huber Martin H. Jr.	TSRO	Restricted Stock Units	D - Sale to Issuer	D			-4.447		0
2019-01-22	2019-01-22	4	Huber Martin H. Jr.	TSRO	Restricted Stock Units	D - Sale to Issuer	D			-8.750		0
2019-01-22	2019-01-22	4	Huber Martin H. Jr.	TSRO	Restricted Stock Units	D - Sale to Issuer	D			-1.250		0
2019-01-22	2019-01-22	4	Huber Martin H. Jr.	TSRO	Common Stock	U - Other	D		75,0000	-12.206	-915		0
2019-01-22	2019-01-22	4	MOULDER LEON O JR	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	55,84		-87.873		0
2019-01-22	2019-01-22	4	MOULDER LEON O JR	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	178,95		-24.260		0
2019-01-22	2019-01-22	4	MOULDER LEON O JR	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	43,39		-100.000		0
2019-01-22	2019-01-22	4	MOULDER LEON O JR	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	55,11		-140.000		0
2019-01-22	2019-01-22	4	MOULDER LEON O JR	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	33,74		-125.000		0
2019-01-22	2019-01-22	4	MOULDER LEON O JR	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	24,18		-200.000		0
2019-01-22	2019-01-22	4	MOULDER LEON O JR	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	6,62		-371.428		0
2019-01-22	2019-01-22	4	MOULDER LEON O JR	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	1,33		-314.285		0
2019-01-22	2019-01-22	4	MOULDER LEON O JR	TSRO	Restricted Stock Units	D - Sale to Issuer	D			-50.000		0
2019-01-22	2019-01-22	4	MOULDER LEON O JR	TSRO	Restricted Stock Units	D - Sale to Issuer	D			-10.007		0
2019-01-22	2019-01-22	4	MOULDER LEON O JR	TSRO	Restricted Stock Units	D - Sale to Issuer	D			-25.000		0
2019-01-22	2019-01-22	4	MOULDER LEON O JR By The Leon Moulder Revocable Trust	TSRO	Common Stock	U - Other	I		75,0000	-5.000	-375		0
2019-01-22	2019-01-22	4	MOULDER LEON O JR	TSRO	Common Stock	U - Other	D		75,0000	-1.034.664	-77.600		0
2019-01-22	2019-01-22	4	Nicholson Garry A	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	46,89		-7.209		0
2019-01-22	2019-01-22	4	Nicholson Garry A	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	149,22		-12.000		0
2019-01-22	2019-01-22	4	Nicholson Garry A	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	47,27		-12.000		0
2019-01-22	2019-01-22	4	Nicholson Garry A	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	60,77		-25.000		0
2019-01-22	2019-01-22	4	Nicholson Garry A	TSRO	Director Restricted Stock Units	D - Sale to Issuer	D			-4.052		0
2019-01-22	2019-01-22	4	Nicholson Garry A	TSRO	Common Stock	U - Other	D		75,0000	-1.671	-125		0
2019-01-22	2019-01-22	4	Oliveira Orlando	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	55,84		-25.963		0
2019-01-22	2019-01-22	4	Oliveira Orlando	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	178,95		-10.782		0
2019-01-22	2019-01-22	4	Oliveira Orlando	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	43,39		-10.938		0
2019-01-22	2019-01-22	4	Oliveira Orlando	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	51,69		-14.063		0
2019-01-22	2019-01-22	4	Oliveira Orlando	TSRO	Restricted Stock Units	D - Sale to Issuer	D			-18.182		0
2019-01-22	2019-01-22	4	Oliveira Orlando	TSRO	Restricted Stock Units	D - Sale to Issuer	D			-4.447		0
2019-01-22	2019-01-22	4	Oliveira Orlando	TSRO	Restricted Stock Units	D - Sale to Issuer	D			-8.750		0
2019-01-22	2019-01-22	4	Oliveira Orlando	TSRO	Restricted Stock Units	D - Sale to Issuer	D			-1.250		0
2019-01-22	2019-01-22	4	Oliveira Orlando	TSRO	Common Stock	U - Other	D		75,0000	-29.378	-2.203		0
2019-01-22	2019-01-22	4	Patel Kavita	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	46,89		-7.209		0
2019-01-22	2019-01-22	4	Patel Kavita	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	149,22		-12.000		0
2019-01-22	2019-01-22	4	Patel Kavita	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	44,03		-24.000		0
2019-01-22	2019-01-22	4	Patel Kavita	TSRO	Director Restricted Stock Units	D - Sale to Issuer	D			-4.052		0
2019-01-22	2019-01-22	4	Patel Kavita	TSRO	Common Stock	U - Other	D		75,0000	-2.757	-207		0
2019-01-22	2019-01-22	4	PEARSON TIMOTHY R	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	55,84		-31.954		0
2019-01-22	2019-01-22	4	PEARSON TIMOTHY R	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	178,95		-10.782		0
2019-01-22	2019-01-22	4	PEARSON TIMOTHY R	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	43,39		-35.000		0
2019-01-22	2019-01-22	4	PEARSON TIMOTHY R	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	55,11		-55.000		0
2019-01-22	2019-01-22	4	PEARSON TIMOTHY R	TSRO	Employee Stock Option (right to buy)	D - Sale to Issuer	D	25,27		-125.000		0
2019-01-22	2019-01-22	4	PEARSON TIMOTHY R	TSRO	Restricted Stock Units	D - Sale to Issuer	D			-18.182		0
2019-01-22	2019-01-22	4	PEARSON TIMOTHY R	TSRO	Restricted Stock Units	D - Sale to Issuer	D			-4.447		0
2019-01-22	2019-01-22	4	PEARSON TIMOTHY R	TSRO	Restricted Stock Units	D - Sale to Issuer	D			-8.750		0
2019-01-22	2019-01-22	4	PEARSON TIMOTHY R	TSRO	Common Stock	U - Other	D		75,0000	-6.211	-466		0
2019-01-22	2019-01-22	4	Witz Pascale	TSRO	Director Nonqualified Stock Option (right to buy)	D - Sale to Issuer	D	46,89		-14.221		0
2019-01-22	2019-01-22	4	Witz Pascale	TSRO	Director Restricted Stock Units	D - Sale to Issuer	D			-8.104		0
2019-01-22	2019-01-22	4	Witz Pascale	TSRO	Common Stock	U - Other	D		75,0000	-1.279	-96		0
2018-12-21	2018-12-20	4	COVINO GREGORY F	TSRO	Restricted Stock Units	M - Exercise	D			-3.055		1.525
2018-12-21	2018-12-20	4	COVINO GREGORY F	TSRO	Common Stock	F - Taxes	D		73,1000	-899	-66		2.156
2018-12-21	2018-12-20	4	COVINO GREGORY F	TSRO	Common Stock	M - Exercise	D			3.055			3.055
2018-12-21	2018-12-20	4	Oliveira Orlando	TSRO	Employee Stock Option (right to buy)	M - Exercise	D	51,69		-39.062		14.063
2018-12-21	2018-12-20	4	Oliveira Orlando	TSRO	Employee Stock Option (right to buy)	M - Exercise	D	43,39		-18.229		10.938
2018-12-21	2018-12-20	4	Oliveira Orlando	TSRO	Employee Stock Option (right to buy)	M - Exercise	D	55,84		-5.991		25.963
2018-12-21	2018-12-20	4	Oliveira Orlando	TSRO	Common Stock	F - Taxes	D		73,1000	-44.158	-3.228		29.378
2018-12-21	2018-12-20	4	Oliveira Orlando	TSRO	Common Stock	M - Exercise	D		51,6900	39.062	2.019		73.536
2018-12-21	2018-12-20	4	Oliveira Orlando	TSRO	Common Stock	M - Exercise	D		43,3900	18.229	791		34.474
2018-12-21	2018-12-20	4	Oliveira Orlando	TSRO	Common Stock	M - Exercise	D		55,8400	5.991	335		16.245
2018-12-21	2018-12-20	4	Hedley Mary Lynne	TSRO	Employee Stock Option (right to buy)	M - Exercise	D	6,62		-23.390		296.101
2018-12-21	2018-12-20	4	Hedley Mary Lynne	TSRO	Common Stock	F - Taxes	D		73,1000	-11.572	-846		26.816
2018-12-21	2018-12-20	4	Hedley Mary Lynne	TSRO	Common Stock	M - Exercise	D		6,6150	23.390	155		38.388
2018-09-25	2018-09-24	4	Huber Martin H. Jr.	TSRO	Common Stock	S - Sale	D		37,6300	-371	-14		12.206
2018-09-25	2018-09-21	4	Huber Martin H. Jr.	TSRO	Restricted Stock Units	M - Exercise	D			-1.250		1.250
2018-09-25	2018-09-21	4	Huber Martin H. Jr.	TSRO	Common Stock	M - Exercise	D			1.250			12.577
2018-09-05	2018-09-04	4	Oliveira Orlando	TSRO	Common Stock	S - Sale	D		32,4400	-72	-2		10.254
2018-09-05	2018-09-01	4	Oliveira Orlando	TSRO	Restricted Stock Units	M - Exercise	D			-1.250		1.250
2018-09-05	2018-09-01	4	Oliveira Orlando	TSRO	Common Stock	M - Exercise	D			1.250			10.326
2018-08-09	2018-08-07	4	ORONSKY ARNOLD L	TSRO	Director Nonqualified Stock Option (right to buy)	M - Exercise	D	26,36		-10.000		0
2018-08-09	2018-08-07	4	ORONSKY ARNOLD L	TSRO	Common Stock	S - Sale	D		26,7721	-10.000	-268		2.479
2018-08-09	2018-08-07	4	ORONSKY ARNOLD L	TSRO	Common Stock	M - Exercise	D			10.000			12.479
2018-08-03	2018-08-01	4	Farmer Joseph L	TSRO	Restricted Stock Units	M - Exercise	D			-625		1.250
2018-08-03	2018-08-01	4	Farmer Joseph L	TSRO	Common Stock	S - Sale	D		34,3700	-187	-6		8.292
2018-08-03	2018-08-01	4	Farmer Joseph L	TSRO	Common Stock	M - Exercise	D			625			8.479
2018-07-03	2018-06-01	4/A	Witz Pascale	TSRO	Director Restricted Stock Units	A - Award	D			8.104		8.104
2018-07-03	2018-06-01	4/A	Witz Pascale	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	46,89		14.221		14.221
2018-07-03	2018-06-01	4/A	Witz Pascale	TSRO	Common Stock	A - Award	D			1.279			1.279
2018-06-14	2018-06-12	4	Alleva Lawrence M	TSRO	Director Nonqualified Stock Option (right to buy)	M - Exercise	D	6,62		-7.142		0
2018-06-14	2018-06-12	4	Alleva Lawrence M	TSRO	Common Stock	S - Sale	D		43,4600	-4.200	-183		29.902
2018-06-14	2018-06-12	4	Alleva Lawrence M	TSRO	Common Stock	S - Sale	D		42,6200	-2.942	-125		34.102
2018-06-14	2018-06-12	4	Alleva Lawrence M	TSRO	Common Stock	M - Exercise	D		6,6150	7.142	47		37.044
2018-06-06	2018-06-01	4	Alleva Lawrence M	TSRO	Director Restricted Stock Units	A - Award	D			4.052		4.052
2018-06-06	2018-06-01	4	Alleva Lawrence M	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	46,89		7.209		7.209
2018-06-06	2018-06-01	4	Alleva Lawrence M	TSRO	Common Stock	A - Award	D			1.599			29.902
2018-06-05	2018-06-01	4	SEIDENBERG BETH C	TSRO	Director Restricted Stock Units	A - Award	D			4.052		4.052
2018-06-05	2018-06-01	4	SEIDENBERG BETH C	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	46,89		7.209		7.209
2018-06-05	2018-06-01	4	SEIDENBERG BETH C	TSRO	Common Stock	A - Award	D			1.332			45.907
2018-06-05	2018-06-01	4	Armitage James O	TSRO	Director Restricted Stock Units	A - Award	D			4.052		4.052
2018-06-05	2018-06-01	4	Armitage James O	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	46,89		7.209		7.209
2018-06-05	2018-06-01	4	COLLIER EARL M JR	TSRO	Director Restricted Stock Units	A - Award	D			4.052		4.052
2018-06-05	2018-06-01	4	COLLIER EARL M JR	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	46,89		7.209		7.209
2018-06-05	2018-06-01	4	COLLIER EARL M JR	TSRO	Common Stock	A - Award	D			1.631			2.090
2018-06-05	2018-06-01	4	Nicholson Garry A	TSRO	Director Restricted Stock Units	A - Award	D			4.052		4.052
2018-06-05	2018-06-01	4	Nicholson Garry A	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	46,89		7.209		7.209
2018-06-05	2018-06-01	4	Patel Kavita	TSRO	Director Restricted Stock Units	A - Award	D			4.052		4.052
2018-06-05	2018-06-01	4	Patel Kavita	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	46,89		7.209		7.209
2018-06-05	2018-06-01	4	Patel Kavita	TSRO	Common Stock	A - Award	D			1.226			2.757
2018-06-05	2018-06-01	4	Witz Pascale	TSRO	Director Restricted Stock Units	A - Award	D			4.052		4.052
2018-06-05	2018-06-01	4	Witz Pascale	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	46,89		7.209		7.209
2018-06-05	2018-06-01	4	Witz Pascale	TSRO	Common Stock	A - Award	D			1.279			1.279
2018-06-05	2018-06-01	4	MOTT DAVID M	TSRO	Director Restricted Stock Units	A - Award	D			4.052		4.052
2018-06-05	2018-06-01	4	MOTT DAVID M	TSRO	Director Nonqualified Stock Option (Right to Buy)	A - Award	D	46,89		7.209		7.209
2018-06-05	2018-06-01	4	MOTT DAVID M	TSRO	Common Stock	A - Award	D			2.537			15.362
2018-03-09	2018-03-08	4	Oliveira Orlando	TSRO	Common Stock	S - Sale	D		69,8800	-3.000	-210		9.076
2018-03-06	2018-03-06	4	Viswanathan Ravi See Note 11	TSRO	Common Stock	P - Purchase	I		59,8154	3.159	189		739.516
2018-03-06	2018-03-06	4	Viswanathan Ravi See Note 2	TSRO	Common Stock	P - Purchase	I		59,8154	12.634	756		9.681.129
2018-03-06	2018-03-05	4	Viswanathan Ravi See Note 11	TSRO	Common Stock	P - Purchase	I		59,7642	4.311	258		736.357
2018-03-06	2018-03-05	4	Viswanathan Ravi See Note 11	TSRO	Common Stock	P - Purchase	I		59,1460	400	24		732.046
2018-03-06	2018-03-05	4	Viswanathan Ravi See Note 11	TSRO	Common Stock	P - Purchase	I		58,2815	7.557	440		731.646
2018-03-06	2018-03-05	4	Viswanathan Ravi See Note 2	TSRO	Common Stock	P - Purchase	I		59,7642	17.248	1.031		9.668.495
2018-03-06	2018-03-05	4	Viswanathan Ravi See Note 2	TSRO	Common Stock	P - Purchase	I		59,1460	1.600	95		9.651.247
2018-03-06	2018-03-05	4	Viswanathan Ravi See Note 2	TSRO	Common Stock	P - Purchase	I		58,2815	30.321	1.767		9.649.647
2018-03-06	2018-03-02	4	Viswanathan Ravi See Note 11	TSRO	Common Stock	P - Purchase	I		57,3444	4.465	256		724.089
2018-03-06	2018-03-02	4	Viswanathan Ravi See Note 11	TSRO	Common Stock	P - Purchase	I		56,6604	1.020	58		719.624
2018-03-06	2018-03-02	4	Viswanathan Ravi See Note 11	TSRO	Common Stock	P - Purchase	I		55,0094	1.600	88		718.604
2018-03-06	2018-03-02	4	Viswanathan Ravi See Note 11	TSRO	Common Stock	P - Purchase	I		54,3216	6.575	357		717.004
2018-03-06	2018-03-02	4	Viswanathan Ravi See Note 2	TSRO	Common Stock	P - Purchase	I		57,3444	17.859	1.024		9.619.326
2018-03-06	2018-03-02	4	Viswanathan Ravi See Note 2	TSRO	Common Stock	P - Purchase	I		56,6604	4.080	231		9.601.467
2018-03-06	2018-03-02	4	Viswanathan Ravi See Note 2	TSRO	Common Stock	P - Purchase	I		55,0094	6.399	352		9.597.387
2018-03-06	2018-03-02	4	Viswanathan Ravi See Note 2	TSRO	Common Stock	P - Purchase	I		54,3216	26.304	1.429		9.590.988
2018-03-06	2018-03-06	4	SANDELL SCOTT D See Note 11	TSRO	Common Stock	P - Purchase	I		59,8154	3.159	189		739.516
2018-03-06	2018-03-06	4	SANDELL SCOTT D See Note 2	TSRO	Common Stock	P - Purchase	I		59,8154	12.634	756		9.681.129
2018-03-06	2018-03-05	4	SANDELL SCOTT D See Note 11	TSRO	Common Stock	P - Purchase	I		59,7642	4.311	258		736.357
2018-03-06	2018-03-05	4	SANDELL SCOTT D See Note 11	TSRO	Common Stock	P - Purchase	I		59,1460	400	24		732.046
2018-03-06	2018-03-05	4	SANDELL SCOTT D See Note 11	TSRO	Common Stock	P - Purchase	I		58,2815	7.557	440		731.646
2018-03-06	2018-03-05	4	SANDELL SCOTT D See Note 2	TSRO	Common Stock	P - Purchase	I		59,7642	17.248	1.031		9.668.495
2018-03-06	2018-03-05	4	SANDELL SCOTT D See Note 2	TSRO	Common Stock	P - Purchase	I		59,1460	1.600	95		9.651.247
2018-03-06	2018-03-05	4	SANDELL SCOTT D See Note 2	TSRO	Common Stock	P - Purchase	I		58,2815	30.321	1.767		9.649.647
2018-03-06	2018-03-02	4	SANDELL SCOTT D See Note 11	TSRO	Common Stock	P - Purchase	I		57,3444	4.465	256		724.089
2018-03-06	2018-03-02	4	SANDELL SCOTT D See Note 11	TSRO	Common Stock	P - Purchase	I		56,6604	1.020	58		719.624
2018-03-06	2018-03-02	4	SANDELL SCOTT D See Note 11	TSRO	Common Stock	P - Purchase	I		55,0094	1.600	88		718.604
2018-03-06	2018-03-02	4	SANDELL SCOTT D See Note 11	TSRO	Common Stock	P - Purchase	I		54,3216	6.575	357		717.004
2018-03-06	2018-03-02	4	SANDELL SCOTT D See Note 2	TSRO	Common Stock	P - Purchase	I		57,3444	17.859	1.024		9.619.326
2018-03-06	2018-03-02	4	SANDELL SCOTT D See Note 2	TSRO	Common Stock	P - Purchase	I		56,6604	4.080	231		9.601.467
2018-03-06	2018-03-02	4	SANDELL SCOTT D See Note 2	TSRO	Common Stock	P - Purchase	I		55,0094	6.399	352		9.597.387
2018-03-06	2018-03-02	4	SANDELL SCOTT D See Note 2	TSRO	Common Stock	P - Purchase	I		54,3216	26.304	1.429		9.590.988
2018-03-06	2018-03-06	4	NEW ENTERPRISE ASSOCIATES 13 LP	TSRO	Common Stock	P - Purchase	D		59,8154	12.634	756		9.681.129
2018-03-06	2018-03-05	4	NEW ENTERPRISE ASSOCIATES 13 LP	TSRO	Common Stock	P - Purchase	D		59,7642	17.248	1.031		9.668.495
2018-03-06	2018-03-05	4	NEW ENTERPRISE ASSOCIATES 13 LP	TSRO	Common Stock	P - Purchase	D		59,1460	1.600	95		9.651.247
2018-03-06	2018-03-05	4	NEW ENTERPRISE ASSOCIATES 13 LP	TSRO	Common Stock	P - Purchase	D		58,2815	30.321	1.767		9.649.647
2018-03-06	2018-03-02	4	NEW ENTERPRISE ASSOCIATES 13 LP	TSRO	Common Stock	P - Purchase	D		57,3444	17.859	1.024		9.619.326
2018-03-06	2018-03-02	4	NEW ENTERPRISE ASSOCIATES 13 LP	TSRO	Common Stock	P - Purchase	D		56,6604	4.080	231		9.601.467
2018-03-06	2018-03-02	4	NEW ENTERPRISE ASSOCIATES 13 LP	TSRO	Common Stock	P - Purchase	D		55,0094	6.399	352		9.597.387
2018-03-06	2018-03-02	4	NEW ENTERPRISE ASSOCIATES 13 LP	TSRO	Common Stock	P - Purchase	D		54,3216	26.304	1.429		9.590.988
2018-03-06	2018-03-06	4	MOTT DAVID M See Note 11	TSRO	Common Stock	P - Purchase	I		59,8154	3.159	189		739.516
2018-03-06	2018-03-06	4	MOTT DAVID M See Note 2	TSRO	Common Stock	P - Purchase	I		59,8154	12.634	756		9.681.129
2018-03-06	2018-03-05	4	MOTT DAVID M See Note 11	TSRO	Common Stock	P - Purchase	I		59,7642	4.311	258		736.357
2018-03-06	2018-03-05	4	MOTT DAVID M See Note 11	TSRO	Common Stock	P - Purchase	I		59,1460	400	24		732.046
2018-03-06	2018-03-05	4	MOTT DAVID M See Note 11	TSRO	Common Stock	P - Purchase	I		58,2815	7.557	440		731.646
2018-03-06	2018-03-05	4	MOTT DAVID M See Note 2	TSRO	Common Stock	P - Purchase	I		59,7642	17.248	1.031		9.668.495
2018-03-06	2018-03-05	4	MOTT DAVID M See Note 2	TSRO	Common Stock	P - Purchase	I		59,1460	1.600	95		9.651.247
2018-03-06	2018-03-05	4	MOTT DAVID M See Note 2	TSRO	Common Stock	P - Purchase	I		58,2815	30.321	1.767		9.649.647
2018-03-06	2018-03-02	4	MOTT DAVID M See Note 11	TSRO	Common Stock	P - Purchase	I		57,3444	4.465	256		724.089
2018-03-06	2018-03-02	4	MOTT DAVID M See Note 11	TSRO	Common Stock	P - Purchase	I		56,6604	1.020	58		719.624
2018-03-06	2018-03-02	4	MOTT DAVID M See Note 11	TSRO	Common Stock	P - Purchase	I		55,0094	1.600	88		718.604
2018-03-06	2018-03-02	4	MOTT DAVID M See Note 11	TSRO	Common Stock	P - Purchase	I		54,3216	6.575	357		717.004
2018-03-06	2018-03-02	4	MOTT DAVID M See Note 2	TSRO	Common Stock	P - Purchase	I		57,3444	17.859	1.024		9.619.326
2018-03-06	2018-03-02	4	MOTT DAVID M See Note 2	TSRO	Common Stock	P - Purchase	I		56,6604	4.080	231		9.601.467
2018-03-06	2018-03-02	4	MOTT DAVID M See Note 2	TSRO	Common Stock	P - Purchase	I		55,0094	6.399	352		9.597.387
2018-03-06	2018-03-02	4	MOTT DAVID M See Note 2	TSRO	Common Stock	P - Purchase	I		54,3216	26.304	1.429		9.590.988
2018-03-06	2018-03-06	4	BARRETT M JAMES See Note 2	TSRO	Common Stock	P - Purchase	I		59,8154	12.634	756		9.681.129
2018-03-06	2018-03-05	4	BARRETT M JAMES See Note 2	TSRO	Common Stock	P - Purchase	I		59,7642	17.248	1.031		9.668.495
2018-03-06	2018-03-05	4	BARRETT M JAMES See Note 2	TSRO	Common Stock	P - Purchase	I		59,1460	1.600	95		9.651.247
2018-03-06	2018-03-05	4	BARRETT M JAMES See Note 2	TSRO	Common Stock	P - Purchase	I		58,2815	30.321	1.767		9.649.647
2018-03-06	2018-03-02	4	BARRETT M JAMES See Note 2	TSRO	Common Stock	P - Purchase	I		57,3444	17.859	1.024		9.619.326
2018-03-06	2018-03-02	4	BARRETT M JAMES See Note 2	TSRO	Common Stock	P - Purchase	I		56,6604	4.080	231		9.601.467
2018-03-06	2018-03-02	4	BARRETT M JAMES See Note 2	TSRO	Common Stock	P - Purchase	I		55,0094	6.399	352		9.597.387
2018-03-06	2018-03-02	4	BARRETT M JAMES See Note 2	TSRO	Common Stock	P - Purchase	I		54,3216	26.304	1.429		9.590.988
2018-03-06	2018-03-06	4	BARRIS PETER J See Note 11	TSRO	Common Stock	P - Purchase	I		59,8154	3.159	189		739.516
2018-03-06	2018-03-06	4	BARRIS PETER J See Note 2	TSRO	Common Stock	P - Purchase	I		59,8154	12.634	756		9.681.129
2018-03-06	2018-03-05	4	BARRIS PETER J See Note 11	TSRO	Common Stock	P - Purchase	I		59,7642	4.311	258		736.357
2018-03-06	2018-03-05	4	BARRIS PETER J See Note 11	TSRO	Common Stock	P - Purchase	I		59,1460	400	24		732.046
2018-03-06	2018-03-05	4	BARRIS PETER J See Note 11	TSRO	Common Stock	P - Purchase	I		58,2815	7.557	440		731.646
2018-03-06	2018-03-05	4	BARRIS PETER J See Note 2	TSRO	Common Stock	P - Purchase	I		59,7642	17.248	1.031		9.668.495
2018-03-06	2018-03-05	4	BARRIS PETER J See Note 2	TSRO	Common Stock	P - Purchase	I		59,1460	1.600	95		9.651.247
2018-03-06	2018-03-05	4	BARRIS PETER J See Note 2	TSRO	Common Stock	P - Purchase	I		58,2815	30.321	1.767		9.649.647
2018-03-06	2018-03-02	4	BARRIS PETER J See Note 11	TSRO	Common Stock	P - Purchase	I		57,3444	4.465	256		724.089
2018-03-06	2018-03-02	4	BARRIS PETER J See Note 11	TSRO	Common Stock	P - Purchase	I		56,6604	1.020	58		719.624
2018-03-06	2018-03-02	4	BARRIS PETER J See Note 11	TSRO	Common Stock	P - Purchase	I		55,0094	1.600	88		718.604
2018-03-06	2018-03-02	4	BARRIS PETER J See Note 11	TSRO	Common Stock	P - Purchase	I		54,3216	6.575	357		717.004
2018-03-06	2018-03-02	4	BARRIS PETER J See Note 2	TSRO	Common Stock	P - Purchase	I		57,3444	17.859	1.024		9.619.326
2018-03-06	2018-03-02	4	BARRIS PETER J See Note 2	TSRO	Common Stock	P - Purchase	I		56,6604	4.080	231		9.601.467
2018-03-06	2018-03-02	4	BARRIS PETER J See Note 2	TSRO	Common Stock	P - Purchase	I		55,0094	6.399	352		9.597.387
2018-03-06	2018-03-02	4	BARRIS PETER J See Note 2	TSRO	Common Stock	P - Purchase	I		54,3216	26.304	1.429		9.590.988
2018-03-06	2018-03-06	4	BASKETT FOREST See Note 11	TSRO	Common Stock	P - Purchase	I		59,8154	3.159	189		739.516
2018-03-06	2018-03-06	4	BASKETT FOREST See Note 2	TSRO	Common Stock	P - Purchase	I		59,8154	12.634	756		9.681.129
2018-03-06	2018-03-05	4	BASKETT FOREST See Note 11	TSRO	Common Stock	P - Purchase	I		59,7642	4.311	258		736.357
2018-03-06	2018-03-05	4	BASKETT FOREST See Note 11	TSRO	Common Stock	P - Purchase	I		59,1460	400	24		732.046
2018-03-06	2018-03-05	4	BASKETT FOREST See Note 11	TSRO	Common Stock	P - Purchase	I		58,2815	7.557	440		731.646
2018-03-06	2018-03-05	4	BASKETT FOREST See Note 2	TSRO	Common Stock	P - Purchase	I		59,7642	17.248	1.031		9.668.495
2018-03-06	2018-03-05	4	BASKETT FOREST See Note 2	TSRO	Common Stock	P - Purchase	I		59,1460	1.600	95		9.651.247
2018-03-06	2018-03-05	4	BASKETT FOREST See Note 2	TSRO	Common Stock	P - Purchase	I		58,2815	30.321	1.767		9.649.647
2018-03-06	2018-03-02	4	BASKETT FOREST See Note 11	TSRO	Common Stock	P - Purchase	I		57,3444	4.465	256		724.089
2018-03-06	2018-03-02	4	BASKETT FOREST See Note 11	TSRO	Common Stock	P - Purchase	I		56,6604	1.020	58		719.624
2018-03-06	2018-03-02	4	BASKETT FOREST See Note 11	TSRO	Common Stock	P - Purchase	I		55,0094	1.600	88		718.604
2018-03-06	2018-03-02	4	BASKETT FOREST See Note 11	TSRO	Common Stock	P - Purchase	I		54,3216	6.575	357		717.004
2018-03-06	2018-03-02	4	BASKETT FOREST See Note 2	TSRO	Common Stock	P - Purchase	I		57,3444	17.859	1.024		9.619.326
2018-03-06	2018-03-02	4	BASKETT FOREST See Note 2	TSRO	Common Stock	P - Purchase	I		56,6604	4.080	231		9.601.467
2018-03-06	2018-03-02	4	BASKETT FOREST See Note 2	TSRO	Common Stock	P - Purchase	I		55,0094	6.399	352		9.597.387
2018-03-06	2018-03-02	4	BASKETT FOREST See Note 2	TSRO	Common Stock	P - Purchase	I		54,3216	26.304	1.429		9.590.988
2018-03-06	2018-03-06	4	KERINS PATRICK J See Note 2	TSRO	Common Stock	P - Purchase	I		59,8154	12.634	756		9.681.129
2018-03-06	2018-03-05	4	KERINS PATRICK J See Note 2	TSRO	Common Stock	P - Purchase	I		59,7642	17.248	1.031		9.668.495
2018-03-06	2018-03-05	4	KERINS PATRICK J See Note 2	TSRO	Common Stock	P - Purchase	I		59,1460	1.600	95		9.651.247
2018-03-06	2018-03-05	4	KERINS PATRICK J See Note 2	TSRO	Common Stock	P - Purchase	I		58,2815	30.321	1.767		9.649.647
2018-03-06	2018-03-02	4	KERINS PATRICK J See Note 2	TSRO	Common Stock	P - Purchase	I		57,3444	17.859	1.024		9.619.326
2018-03-06	2018-03-02	4	KERINS PATRICK J See Note 2	TSRO	Common Stock	P - Purchase	I		56,6604	4.080	231		9.601.467
2018-03-06	2018-03-02	4	KERINS PATRICK J See Note 2	TSRO	Common Stock	P - Purchase	I		55,0094	6.399	352		9.597.387
2018-03-06	2018-03-02	4	KERINS PATRICK J See Note 2	TSRO	Common Stock	P - Purchase	I		54,3216	26.304	1.429		9.590.988
2018-03-05	2018-03-02	4	Farmer Joseph L	TSRO	Common Stock	S - Sale	D		54,8600	-2.634	-145		7.854
2018-03-05	2018-03-01	4	Farmer Joseph L	TSRO	Employee Stock Option (right to buy)	A - Award	D	55,84		31.954		31.954
2018-03-05	2018-03-01	4	Farmer Joseph L	TSRO	Restricted Stock Units	A - Award	D			18.182		18.182
2018-03-05	2018-03-01	4	Farmer Joseph L	TSRO	Restricted Stock Units	M - Exercise	D			-1.483		4.447
2018-03-05	2018-03-01	4	Farmer Joseph L	TSRO	Restricted Stock Units	M - Exercise	D			-4.375		8.750
2018-03-05	2018-03-01	4	Farmer Joseph L	TSRO	Common Stock	M - Exercise	D			1.483			10.488
2018-03-05	2018-03-01	4	Farmer Joseph L	TSRO	Common Stock	M - Exercise	D			4.375			9.005
2018-03-05	2018-03-01	4	Bogle Grant C.	TSRO	Employee Stock Option (right to buy)	A - Award	D	55,84		31.954		31.954
2018-03-05	2018-03-01	4	Bogle Grant C.	TSRO	Restricted Stock Units	A - Award	D			18.182		18.182
2018-03-05	2018-03-01	4	Bogle Grant C.	TSRO	Restricted Stock Units	M - Exercise	D			-1.483		4.447
2018-03-05	2018-03-01	4	Bogle Grant C.	TSRO	Restricted Stock Units	M - Exercise	D			-4.375		8.750
2018-03-05	2018-03-01	4	Bogle Grant C.	TSRO	Common Stock	S - Sale	D		54,8500	-1.809	-99		4.431
2018-03-05	2018-03-01	4	Bogle Grant C.	TSRO	Common Stock	M - Exercise	D			1.483			6.240
2018-03-05	2018-03-01	4	Bogle Grant C.	TSRO	Common Stock	M - Exercise	D			4.375			4.757
2018-03-05	2018-03-01	4	MOULDER LEON O JR	TSRO	Employee Stock Option (right to buy)	A - Award	D	55,84		87.873		87.873
2018-03-05	2018-03-01	4	MOULDER LEON O JR	TSRO	Restricted Stock Units	A - Award	D			50.000		50.000
2018-03-05	2018-03-01	4	MOULDER LEON O JR	TSRO	Restricted Stock Units	M - Exercise	D			-3.336		10.007
2018-03-05	2018-03-01	4	MOULDER LEON O JR	TSRO	Restricted Stock Units	M - Exercise	D			-12.500		25.000
2018-03-05	2018-03-01	4	MOULDER LEON O JR	TSRO	Common Stock	M - Exercise	D			3.336			1.034.664
2018-03-05	2018-03-01	4	MOULDER LEON O JR	TSRO	Common Stock	M - Exercise	D			12.500			1.031.328
2018-03-05	2018-03-02	4	PEARSON TIMOTHY R	TSRO	Common Stock	S - Sale	D		54,8600	-2.575	-141		6.211
2018-03-05	2018-03-01	4	PEARSON TIMOTHY R	TSRO	Employee Stock Option (right to buy)	A - Award	D	55,84		31.954		31.954
2018-03-05	2018-03-01	4	PEARSON TIMOTHY R	TSRO	Restricted Stock Units	A - Award	D			18.182		18.182
2018-03-05	2018-03-01	4	PEARSON TIMOTHY R	TSRO	Restricted Stock Units	M - Exercise	D			-1.483		4.447
2018-03-05	2018-03-01	4	PEARSON TIMOTHY R	TSRO	Restricted Stock Units	M - Exercise	D			-4.375		8.750
2018-03-05	2018-03-01	4	PEARSON TIMOTHY R	TSRO	Common Stock	M - Exercise	D			1.483			8.786
2018-03-05	2018-03-01	4	PEARSON TIMOTHY R	TSRO	Common Stock	M - Exercise	D			4.375			7.303
2018-03-05	2018-03-01	4	Hedley Mary Lynne	TSRO	Employee Stock Option (right to buy)	A - Award	D	55,84		71.896		71.896
2018-03-05	2018-03-01	4	Hedley Mary Lynne	TSRO	Restricted Stock Units	A - Award	D			40.909		40.909
2018-03-05	2018-03-01	4	Hedley Mary Lynne	TSRO	Restricted Stock Units	M - Exercise	D			-2.780		8.339
2018-03-05	2018-03-01	4	Hedley Mary Lynne	TSRO	Restricted Stock Units	M - Exercise	D			-10.000		20.000
2018-03-05	2018-03-01	4	Hedley Mary Lynne	TSRO	Common Stock	S - Sale	D		54,8600	-3.855	-211		14.998
2018-03-05	2018-03-01	4	Hedley Mary Lynne	TSRO	Common Stock	M - Exercise	D			2.780			18.853
2018-03-05	2018-03-01	4	Hedley Mary Lynne	TSRO	Common Stock	M - Exercise	D			10.000			16.073
2018-03-05	2018-03-02	4	Oliveira Orlando	TSRO	Common Stock	S - Sale	D		54,8600	-337	-18		12.076
2018-03-05	2018-03-01	4	Oliveira Orlando	TSRO	Employee Stock Option (right to buy)	A - Award	D	55,84		31.954		31.954
2018-03-05	2018-03-01	4	Oliveira Orlando	TSRO	Restricted Stock Units	A - Award	D			18.182		18.182
2018-03-05	2018-03-01	4	Oliveira Orlando	TSRO	Restricted Stock Units	M - Exercise	D			-1.483		4.447
2018-03-05	2018-03-01	4	Oliveira Orlando	TSRO	Restricted Stock Units	M - Exercise	D			-4.375		8.750
2018-03-05	2018-03-01	4	Oliveira Orlando	TSRO	Common Stock	M - Exercise	D			1.483			12.413
2018-03-05	2018-03-01	4	Oliveira Orlando	TSRO	Common Stock	M - Exercise	D			4.375			10.930
2018-03-05	2018-03-02	4	Huber Martin H. Jr.	TSRO	Common Stock	S - Sale	D		54,8600	-1.803	-99		11.327
2018-03-05	2018-03-01	4	Huber Martin H. Jr.	TSRO	Employee Stock Option (right to buy)	A - Award	D	55,84		39.942		39.942
2018-03-05	2018-03-01	4	Huber Martin H. Jr.	TSRO	Restricted Stock Units	A - Award	D			22.727		22.727
2018-03-05	2018-03-01	4	Huber Martin H. Jr.	TSRO	Restricted Stock Units	M - Exercise	D			-1.483		4.447
2018-03-05	2018-03-01	4	Huber Martin H. Jr.	TSRO	Restricted Stock Units	M - Exercise	D			-4.375		8.750
2018-03-05	2018-03-01	4	Huber Martin H. Jr.	TSRO	Common Stock	M - Exercise	D			1.483			13.130
2018-03-05	2018-03-01	4	Huber Martin H. Jr.	TSRO	Common Stock	M - Exercise	D			4.375			11.647
2018-03-05	2018-03-02	4	MOULDER LEON O JR By The Leon Moulder Revocable Trust	TSRO	Common Stock	P - Purchase	I		57,1400	1.000	57		5.000
2018-03-05	2018-03-02	4	MOULDER LEON O JR By The Leon Moulder Revocable Trust	TSRO	Common Stock	P - Purchase	I		56,8900	1.000	57		4.000
2018-03-05	2018-03-02	4	MOULDER LEON O JR By The Leon Moulder Revocable Trust	TSRO	Common Stock	P - Purchase	I		56,8800	1.000	57		3.000
2018-03-05	2018-03-02	4	MOULDER LEON O JR By The Leon Moulder Revocable Trust	TSRO	Common Stock	P - Purchase	I		56,8700	1.000	57		2.000
2018-03-05	2018-03-02	4	MOULDER LEON O JR By The Leon Moulder Revocable Trust	TSRO	Common Stock	P - Purchase	I		56,8600	1.000	57		1.000
2017-12-15	2017-12-14	4	SEIDENBERG BETH C	TSRO	Common Stock	J - Other	I			-13.219			10.998
2017-12-05	2017-12-04	4	Huber Martin H. Jr.	TSRO	Common Stock	S - Sale	D		85,2400	-829	-71		7.272
2017-12-05	2017-12-01	4	Huber Martin H. Jr.	TSRO	Restricted Stock Units	M - Exercise	D			-1.750		0
2017-12-05	2017-12-01	4	Huber Martin H. Jr.	TSRO	Common Stock	M - Exercise	D			1.750			8.101
2017-11-20	2017-11-16	4	Huber Martin H. Jr.	TSRO	Restricted Stock Units	A - Award	D			1.750		1.750
2017-09-25	2017-09-22	4	Huber Martin H. Jr.	TSRO	Common Stock	S - Sale	D		118,6000	-592	-70		6.351
2017-09-25	2017-09-21	4	Huber Martin H. Jr.	TSRO	Restricted Stock Units	M - Exercise	D			-1.250		2.500
2017-09-25	2017-09-21	4	Huber Martin H. Jr.	TSRO	Common Stock	M - Exercise	D			1.250			6.943
2017-09-20	2017-09-18	4	Armitage James O	TSRO	Director Nonqualified Stock Option (right to buy)	M - Exercise	D	26,36		-10.000		0
2017-09-20	2017-09-18	4	Armitage James O	TSRO	Common Stock	S - Sale	D		117,5800	-5.743	-675		0
2017-09-20	2017-09-18	4	Armitage James O	TSRO	Common Stock	S - Sale	D		116,5200	-4.257	-496		5.743
2017-09-20	2017-09-18	4	Armitage James O	TSRO	Common Stock	M - Exercise	D		26,3600	10.000	264		10.000
2017-09-11	2017-09-11	4	SEIDENBERG BETH C By Samuel B. Seidenberg Irrevocable Trust	TSRO	Common Stock	J - Other	I			663			868
2017-09-11	2017-09-11	4	SEIDENBERG BETH C By Michael J. Seidenberg Irrevocable Trust	TSRO	Common Stock	J - Other	I			663			868
2017-09-11	2017-09-11	4	SEIDENBERG BETH C	TSRO	Common Stock	J - Other	D			22.516			44.575
2017-09-11	2017-09-11	4	SEIDENBERG BETH C	TSRO	Common Stock	J - Other	I			-204.166			0
2017-09-11	2017-09-11	4	SEIDENBERG BETH C	TSRO	Common Stock	J - Other	I			204.166			204.166
2017-09-11	2017-09-11	4	SEIDENBERG BETH C See footnotes	TSRO	Common Stock	J - Other	I			-58.500			168.755
2017-09-11	2017-09-11	4	SEIDENBERG BETH C See footnotes	TSRO	Common Stock	J - Other	I			-667.283			2.018.985
2017-09-06	2017-09-01	4	Bogle Grant C.	TSRO	Employee Stock Option (right to buy)	M - Exercise	D	43,39		-2.917		32.083
2017-09-06	2017-09-01	4	Bogle Grant C.	TSRO	Employee Stock Option (right to buy)	M - Exercise	D	59,71		-8.333		66.667
2017-09-06	2017-09-01	4	Bogle Grant C.	TSRO	Common Stock	S - Sale	D		135,0000	-14.167	-1.913		293
2017-09-06	2017-09-01	4	Bogle Grant C.	TSRO	Common Stock	M - Exercise	D		43,3900	2.917	127		14.460
2017-09-06	2017-09-01	4	Bogle Grant C.	TSRO	Common Stock	M - Exercise	D		59,7100	8.333	498		11.543
2017-09-06	2017-09-05	4	Oliveira Orlando	TSRO	Common Stock	S - Sale	D		132,6600	-71	-9		6.555
2017-09-06	2017-09-01	4	Oliveira Orlando	TSRO	Restricted Stock Units	M - Exercise	D			-1.250		2.500
2017-09-06	2017-09-01	4	Oliveira Orlando	TSRO	Common Stock	M - Exercise	D			1.250			6.626
2017-09-06	2017-09-06	4	English Edward C	TSRO	Employee Stock Option (right to buy)	M - Exercise	D	55,11		-5.000		20.000
2017-09-06	2017-09-06	4	English Edward C	TSRO	Employee Stock Option (right to buy)	M - Exercise	D	24,18		-5.862		4.138
2017-09-06	2017-09-06	4	English Edward C	TSRO	Common Stock, par value $0.0001	S - Sale	D		136,2600	-300	-41		396
2017-09-06	2017-09-06	4	English Edward C	TSRO	Common Stock, par value $0.0001	S - Sale	D		135,4000	-5.102	-691		696
2017-09-06	2017-09-06	4	English Edward C	TSRO	Common Stock, par value $0.0001	S - Sale	D		134,3900	-5.460	-734		5.798
2017-09-06	2017-09-06	4	English Edward C	TSRO	Common Stock, par value $0.0001	M - Exercise	D		55,1100	5.000	276		11.258
2017-09-06	2017-09-06	4	English Edward C	TSRO	Common Stock, par value $0.0001	M - Exercise	D		24,1800	5.862	142		6.258
2017-08-03	2017-08-01	4	Farmer Joseph L	TSRO	Restricted Stock Units	M - Exercise	D			-625		1.875
2017-08-03	2017-08-01	4	Farmer Joseph L	TSRO	Common Stock	M - Exercise	D			625			4.616
2017-06-08	2017-06-06	4	English Edward C	TSRO	Employee Stock Option (right to buy)	M - Exercise	D	33,74		-3.500		6.000
2017-06-08	2017-06-06	4	English Edward C	TSRO	Employee Stock Option (right to buy)	M - Exercise	D	24,18		-5.000		10.000
2017-06-08	2017-06-06	4	English Edward C	TSRO	Common Stock, par value $0.0001	S - Sale	D		142,1600	-362	-51		396
2017-06-08	2017-06-06	4	English Edward C	TSRO	Common Stock, par value $0.0001	S - Sale	D		140,0500	-638	-89		758
2017-06-08	2017-06-06	4	English Edward C	TSRO	Common Stock, par value $0.0001	S - Sale	D		138,8200	-3.400	-472		1.396
2017-06-08	2017-06-06	4	English Edward C	TSRO	Common Stock, par value $0.0001	S - Sale	D		137,9800	-4.100	-566		4.796
2017-06-08	2017-06-06	4	English Edward C	TSRO	Common Stock, par value $0.0001	M - Exercise	D		33,7400	3.500	118		8.896
2017-06-08	2017-06-06	4	English Edward C	TSRO	Common Stock, par value $0.0001	M - Exercise	D		24,1800	5.000	121		5.396
2017-06-05	2017-06-01	4	Alleva Lawrence M	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	149,22		12.000		12.000
2017-06-05	2017-06-01	4	Alleva Lawrence M	TSRO	Common Stock	A - Award	D			469			28.303
2017-06-05	2017-06-01	4	Armitage James O	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	149,22		12.000		12.000
2017-06-05	2017-06-01	4	COLLIER EARL M JR	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	149,22		12.000		12.000
2017-06-05	2017-06-01	4	COLLIER EARL M JR	TSRO	Common Stock	A - Award	D			459			459
2017-06-05	2017-06-01	4	Nicholson Garry A	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	149,22		12.000		12.000
2017-06-05	2017-06-01	4	Nicholson Garry A	TSRO	Common Stock	A - Award	D			402			1.671
2017-06-05	2017-06-01	4	ORONSKY ARNOLD L	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	149,22		12.000		12.000
2017-06-05	2017-06-01	4	ORONSKY ARNOLD L By corporation	TSRO	Common Stock	A - Award	I			335			1.338
2017-06-05	2017-06-01	4	Patel Kavita	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	149,22		12.000		12.000
2017-06-05	2017-06-01	4	Patel Kavita	TSRO	Common Stock	A - Award	D			368			1.531
2017-06-05	2017-06-01	4	SEIDENBERG BETH C	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	149,22		12.000		12.000
2017-06-05	2017-06-01	4	SEIDENBERG BETH C	TSRO	Common Stock	A - Award	D			402			22.059
2017-06-05	2017-06-01	4	MOTT DAVID M	TSRO	Director Nonqualified Stock Option (Right to Buy)	A - Award	D	149,22		12.000		12.000
2017-06-05	2017-06-01	4	MOTT DAVID M	TSRO	Common Stock	A - Award	D			676			12.825
2017-04-04	2017-04-03	4	Huber Martin H. Jr.	TSRO	Common Stock	S - Sale	D		153,0200	-829	-127		5.693
2017-04-04	2017-04-01	4	Huber Martin H. Jr.	TSRO	Restricted Stock Units	M - Exercise	D			-1.750		0
2017-04-04	2017-04-01	4	Huber Martin H. Jr.	TSRO	Common Stock	M - Exercise	D			1.750			6.522
2017-03-29	2017-03-27	4	Huber Martin H. Jr.	TSRO	Restricted Stock Units	A - Award	D			1.750		1.750
2017-03-08	2017-03-06	4	English Edward C	TSRO	Employee Stock Option (right to buy)	M - Exercise	D	33,74		-5.000		9.500
2017-03-08	2017-03-06	4	English Edward C	TSRO	Employee Stock Option (right to buy)	M - Exercise	D	24,18		-5.000		9.500
2017-03-08	2017-03-06	4	English Edward C	TSRO	Common Stock, par value $.0001	S - Sale	D		178,0600	-10.000	-1.781		396
2017-03-08	2017-03-06	4	English Edward C	TSRO	Common Stock, par value $.0001	M - Exercise	D		33,7400	5.000	169		10.396
2017-03-08	2017-03-06	4	English Edward C	TSRO	Common Stock, par value $.0001	M - Exercise	D		24,1800	5.000	121		5.396
2017-03-03	2017-03-02	4	Oliveira Orlando	TSRO	Common Stock	S - Sale	D		177,6100	-249	-44		5.376
2017-03-03	2017-03-01	4	Oliveira Orlando	TSRO	Employee Stock Option (right to buy)	A - Award	D	178,95		10.782		10.782
2017-03-03	2017-03-01	4	Oliveira Orlando	TSRO	Restricted Stock Units	A - Award	D			5.930		5.930
2017-03-03	2017-03-01	4	Oliveira Orlando	TSRO	Restricted Stock Units	M - Exercise	D			-4.375		13.125
2017-03-03	2017-03-01	4	Oliveira Orlando	TSRO	Common Stock	M - Exercise	D			4.375			5.625
2017-03-03	2017-03-02	4	PEARSON TIMOTHY R	TSRO	Common Stock	S - Sale	D		177,6100	-1.447	-257		2.928
2017-03-03	2017-03-01	4	PEARSON TIMOTHY R	TSRO	Employee Stock Option (right to buy)	A - Award	D	178,95		10.782		10.782
2017-03-03	2017-03-01	4	PEARSON TIMOTHY R	TSRO	Restricted Stock Units	A - Award	D			5.930		5.930
2017-03-03	2017-03-01	4	PEARSON TIMOTHY R	TSRO	Restricted Stock Units	M - Exercise	D			-4.375		13.125
2017-03-03	2017-03-01	4	PEARSON TIMOTHY R	TSRO	Common Stock	M - Exercise	D			4.375			4.375
2017-03-03	2017-03-02	4	Bogle Grant C.	TSRO	Common Stock	S - Sale	D		177,6100	-1.447	-257		3.155
2017-03-03	2017-03-01	4	Bogle Grant C.	TSRO	Employee Stock Option (right to buy)	A - Award	D	178,95		10.782		10.782
2017-03-03	2017-03-01	4	Bogle Grant C.	TSRO	Restricted Stock Units	A - Award	D			5.930		5.930
2017-03-03	2017-03-01	4	Bogle Grant C.	TSRO	Restricted Stock Units	M - Exercise	D			-4.375		13.125
2017-03-03	2017-03-01	4	Bogle Grant C.	TSRO	Common Stock	M - Exercise	D			4.375			4.602
2017-03-03	2017-03-01	4	MOULDER LEON O JR	TSRO	Employee Stock Option (right to buy)	A - Award	D	178,95		24.260		24.260
2017-03-03	2017-03-01	4	MOULDER LEON O JR	TSRO	Restricted Stock Units	A - Award	D			13.343		13.343
2017-03-03	2017-03-01	4	MOULDER LEON O JR	TSRO	Common Stock	M - Exercise	D			12.500			1.018.828
2017-03-03	2016-06-24	4	MOULDER LEON O JR	TSRO	Common Stock	G - Gift	D			-100			1.006.328
2017-03-03	2016-03-01	4	MOULDER LEON O JR	TSRO	Restricted Stock Units	M - Exercise	D			-12.500		37.500
2017-03-03	2017-03-02	4	English Edward C	TSRO	Common Stock	S - Sale	D		177,6100	-229	-41		396
2017-03-03	2017-03-01	4	English Edward C	TSRO	Employee Stock Option (right to buy)	A - Award	D	178,95		2.150		2.150
2017-03-03	2017-03-01	4	English Edward C	TSRO	Restricted Stock Units	A - Award	D			1.750		1.750
2017-03-03	2017-03-01	4	English Edward C	TSRO	Restricted Stock Units	M - Exercise	D			-625		1.875
2017-03-03	2017-03-01	4	English Edward C	TSRO	Common Stock	M - Exercise	D			625			625
2017-03-03	2017-03-02	4	Farmer Joseph L	TSRO	Common Stock	S - Sale	D		177,6100	-1.449	-257		3.819
2017-03-03	2017-03-01	4	Farmer Joseph L	TSRO	Employee Stock Option (right to buy)	A - Award	D	178,95		10.782		10.782
2017-03-03	2017-03-01	4	Farmer Joseph L	TSRO	Restricted Stock Units	A - Award	D			5.930		5.930
2017-03-03	2017-03-01	4	Farmer Joseph L	TSRO	Restricted Stock Units	M - Exercise	D			-4.375		13.125
2017-03-03	2017-03-01	4	Farmer Joseph L	TSRO	Common Stock	M - Exercise	D			4.375			5.268
2017-03-03	2017-03-02	4	Hedley Mary Lynne	TSRO	Common Stock	S - Sale	D		177,6100	-3.927	-697		6.073
2017-03-03	2017-03-01	4	Hedley Mary Lynne	TSRO	Employee Stock Option (right to buy)	A - Award	D	178,95		20.216		20.216
2017-03-03	2017-03-01	4	Hedley Mary Lynne	TSRO	Restricted Stock Units	A - Award	D			11.119		11.119
2017-03-03	2017-03-01	4	Hedley Mary Lynne	TSRO	Restricted Stock Units	M - Exercise	D			-10.000		30.000
2017-03-03	2017-03-01	4	Hedley Mary Lynne	TSRO	Common Stock	M - Exercise	D			10.000			10.000
2017-03-03	2017-03-02	4	Huber Martin H. Jr.	TSRO	Common Stock	S - Sale	D		177,6100	-1.428	-254		4.772
2017-03-03	2017-03-01	4	Huber Martin H. Jr.	TSRO	Employee Stock Option (right to buy)	A - Award	D	178,95		10.782		10.782
2017-03-03	2017-03-01	4	Huber Martin H. Jr.	TSRO	Restricted Stock Units	A - Award	D			5.930		5.930
2017-03-03	2017-03-01	4	Huber Martin H. Jr.	TSRO	Restricted Stock Units	M - Exercise	D			-4.375		13.125
2017-03-03	2017-03-01	4	Huber Martin H. Jr.	TSRO	Common Stock	M - Exercise	D			4.375			6.200
2017-03-01		3	Oliveira Orlando	TSRO	Common Stock		D						2.500
2017-03-01		3	Oliveira Orlando	TSRO	Common Stock		D						2.500
2017-01-03	2017-01-03	4	Huber Martin H. Jr.	TSRO	Common Stock	S - Sale	D		136,2600	-190	-26		0
2017-01-03	2017-01-01	4	Huber Martin H. Jr.	TSRO	Common Stock	A - Award	D			500			0
2016-12-14	2016-12-12	4	English Edward C	TSRO	Employee Stock Option (right to buy)	M - Exercise	D	24,18		-5.000		5.000
2016-12-14	2016-12-12	4	English Edward C	TSRO	Employee Stock Option (right to buy)	M - Exercise	D	34,58		-5.000		5.000
2016-12-14	2016-12-12	4	English Edward C	TSRO	Common Stock, par value $.0001	S - Sale	D		129,2000	-8.300	-1.072		0
2016-12-14	2016-12-12	4	English Edward C	TSRO	Common Stock, par value $.0001	S - Sale	D		128,3000	-1.700	-218		8.300
2016-12-14	2016-12-12	4	English Edward C	TSRO	Common Stock, par value $.0001	M - Exercise	D		34,5800	5.000	173		10.000
2016-12-14	2016-12-12	4	English Edward C	TSRO	Common Stock, par value $.0001	M - Exercise	D		24,1800	5.000	121		5.000
2016-11-03	2016-11-02	4	Huber Martin H. Jr.	TSRO	Common Stock	S - Sale	D		121,2900	-327	-40		1.515
2016-11-03	2016-11-01	4	Huber Martin H. Jr.	TSRO	Common Stock	A - Award	D			1.000			1.842
2016-09-23	2016-09-22	4	Huber Martin H. Jr.	TSRO	Common Stock	S - Sale	D		108,1200	-408	-44		842
2016-09-23	2016-09-21	4	Huber Martin H. Jr.	TSRO	Restricted Stock Units	M - Exercise	D			-1.250		3.750
2016-09-23	2016-09-21	4	Huber Martin H. Jr.	TSRO	Common Stock	M - Exercise	D			1.250			1.250
2016-09-09	2016-09-08	4	English Edward C	TSRO	Employee Stock Option (right to buy)	M - Exercise	D	33,74		-3.500		14.500
2016-09-09	2016-09-08	4	English Edward C	TSRO	Employee Stock Option (right to buy)	M - Exercise	D	13,31		-3.500		14.500
2016-09-09	2016-09-08	4	English Edward C	TSRO	Common Stock, par value $.01	S - Sale	D		90,4700	-1.500	-136		0
2016-09-09	2016-09-08	4	English Edward C	TSRO	Common Stock, par value $.01	S - Sale	D		88,9800	-100	-9		1.500
2016-09-09	2016-09-08	4	English Edward C	TSRO	Common Stock, par value $.01	S - Sale	D		88,0000	-5.400	-475		1.600
2016-09-09	2016-09-08	4	English Edward C	TSRO	Common Stock, par value $.01	M - Exercise	D		33,7400	3.500	118		7.000
2016-09-09	2016-09-08	4	English Edward C	TSRO	Common Stock, par value $.01	M - Exercise	D		13,3100	3.500	47		3.500
2016-09-01	2016-08-30	4	Hanke Jeffrey H.	TSRO	Employee Stock Option (right to buy)	M - Exercise	D	56,52		-29.166		70.834
2016-09-01	2016-08-30	4	Hanke Jeffrey H.	TSRO	Common Stock	S - Sale	D		86,0400	-29.166	-2.509		0
2016-09-01	2016-08-30	4	Hanke Jeffrey H.	TSRO	Common Stock	M - Exercise	D		56,5200	29.166	1.648		29.166
2016-07-29	2016-07-27	4	Farmer Joseph L	TSRO	Restricted Stock Units	A - Award	D			2.500		2.500
2016-07-01	2016-06-30	4	Hanke Jeffrey H.	TSRO	Restricted Stock Units	M - Exercise	D			-12.500		38.500
2016-07-01	2016-06-30	4	Hanke Jeffrey H.	TSRO	Common Stock	S - Sale	D		74,6100	-9.700	-724		0
2016-07-01	2016-06-30	4	Hanke Jeffrey H.	TSRO	Common Stock	S - Sale	D		73,4300	-2.800	-206		9.700
2016-07-01	2016-06-30	4	Hanke Jeffrey H.	TSRO	Common Stock	M - Exercise	D			12.500			12.500
2016-06-14	2016-06-10	4	English Edward C	TSRO	Employee Stock Option (right to buy)	M - Exercise	D	33,74		-3.500		18.000
2016-06-14	2016-06-10	4	English Edward C	TSRO	Employee Stock Option (right to buy)	M - Exercise	D	13,31		-3.500		18.000
2016-06-14	2016-06-10	4	English Edward C	TSRO	Common Stock, par value $0.0001	S - Sale	D		41,6800	-100	-4		0
2016-06-14	2016-06-10	4	English Edward C	TSRO	Common Stock, par value $0.0001	S - Sale	D		40,7400	-6.900	-281		100
2016-06-14	2016-06-10	4	English Edward C	TSRO	Common Stock, par value $0.0001	M - Exercise	D		33,7400	3.500	118		7.000
2016-06-14	2016-06-10	4	English Edward C	TSRO	Common Stock, par value $0.0001	M - Exercise	D		13,3100	3.500	47		3.500
2016-06-03	2016-06-01	4	ORONSKY ARNOLD L	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	47,27		12.000		12.000
2016-06-03	2016-06-01	4	SEIDENBERG BETH C	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	47,27		12.000		12.000
2016-06-03	2016-06-01	4	SEIDENBERG BETH C	TSRO	Common Stock	A - Award	D			1.269			21.657
2016-06-03	2016-06-01	4	Armitage James O	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	47,27		12.000		12.000
2016-06-03	2016-06-01	4	COLLIER EARL M JR	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	47,27		12.000		12.000
2016-06-03	2016-06-01	4	MOTT DAVID M	TSRO	Director Nonqualified Stock Option (Right to Buy)	A - Award	D	47,27		12.000		12.000
2016-06-03	2016-06-01	4	MOTT DAVID M	TSRO	Common Stock	A - Award	D			2.115			12.149
2016-06-03	2016-06-01	4	Alleva Lawrence M	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	47,27		12.000		12.000
2016-06-03	2016-06-01	4	Alleva Lawrence M	TSRO	Common Stock	A - Award	D			1.480			27.834
2016-06-03	2016-06-01	4	Nicholson Garry A	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	47,27		12.000		12.000
2016-06-03	2016-06-01	4	Nicholson Garry A	TSRO	Common Stock	A - Award	D			1.269			1.269
2016-06-03	2016-06-01	4	Patel Kavita	TSRO	Common Stock	A - Award	D			1.163			1.163
2016-04-04	2016-03-31	4	Patel Kavita	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	44,03		24.000		24.000
2016-03-30	2016-03-29	4	Khattar Jack A. By the KBT Trust	SUPN	Common Stock	J - Other	I			-7.000			1.094.000
2016-03-30	2016-03-29	4	Khattar Jack A.	SUPN	Common Stock	J - Other	D			7.000			444.124
2016-03-18	2016-03-18	4	ORONSKY ARNOLD L By partnership	TSRO	Common Stock	P - Purchase	I		35,1900	142.085	5.000		2.013.786
2016-03-18	2016-03-18	4	SEIDENBERG BETH C See footnotes	TSRO	Common Stock	P - Purchase	I		35,1900	110.827	3.900		227.255
2016-03-18	2016-03-18	4	SEIDENBERG BETH C See footnotes	TSRO	Common Stock	P - Purchase	I		35,1900	1.310.031	46.100		2.686.268
2016-03-18	2016-03-18	4	NEW ENTERPRISE ASSOCIATES 13 LP	TSRO	Common Stock	P - Purchase	D		35,1900	710.429	25.000		9.564.684
2016-03-18	2016-03-18	4	BARRETT M JAMES See Note 2	TSRO	Common Stock	P - Purchase	I		35,1900	710.429	25.000		9.564.684
2016-03-18	2016-03-18	4	BARRIS PETER J See Note 2	TSRO	Common Stock	P - Purchase	I		35,1900	710.429	25.000		710.429
2016-03-18	2016-03-18	4	BARRIS PETER J See Note 3	TSRO	Common Stock	P - Purchase	I		35,1900	710.429	25.000		710.429
2016-03-18	2016-03-18	4	BASKETT FOREST See Note 2	TSRO	Common Stock	P - Purchase	I		35,1900	710.429	25.000		710.429
2016-03-18	2016-03-18	4	BASKETT FOREST See Note 3	TSRO	Common Stock	P - Purchase	I		35,1900	710.429	25.000		710.429
2016-03-18	2016-03-18	4	KERINS PATRICK J See Note 2	TSRO	Common Stock	P - Purchase	I		35,1900	710.429	25.000		9.564.684
2016-03-18	2016-03-18	4	KOLLURI KRISHNA KITTU See Note 3	TSRO	Common Stock	P - Purchase	I			710.429			710.429
2016-03-18	2016-03-18	4	KOLLURI KRISHNA KITTU See Note 2	TSRO	Common Stock	P - Purchase	I			710.429			711.179
2016-03-18	2016-03-18	4	MOTT DAVID M See Note 2	TSRO	Common Stock	P - Purchase	I		35,1900	710.429	25.000		733.163
2016-03-18	2016-03-18	4	MOTT DAVID M See Note 3	TSRO	Common Stock	P - Purchase	I		35,1900	710.429	25.000		710.429
2016-03-18	2016-03-18	4	SANDELL SCOTT D See Note 2	TSRO	Common Stock	P - Purchase	I		35,1900	710.429	25.000		710.429
2016-03-18	2016-03-18	4	SANDELL SCOTT D See Note 3	TSRO	Common Stock	P - Purchase	I		35,1900	710.429	25.000		710.429
2016-03-18	2016-03-18	4	Viswanathan Ravi See Note 3	TSRO	Common Stock	P - Purchase	I		35,1900	710.429	25.000		710.429
2016-03-18	2016-03-18	4	Viswanathan Ravi See Note 2	TSRO	Common Stock	P - Purchase	I		35,1900	710.429	25.000		710.429
2016-03-18	2016-03-18	4	Weller Harry R See Note 3	TSRO	Common Stock	P - Purchase	I		35,1900	710.429	25.000		10.275.113
2016-03-18	2016-03-18	4	Weller Harry R See Note 2	TSRO	Common Stock	P - Purchase	I		35,1900	710.429	25.000		710.429
2016-03-14	2016-03-10	4	English Edward C	TSRO	Employee Stock Option (right to buy)	M - Exercise	D	13,31		-3.500		21.500
2016-03-14	2016-03-10	4	English Edward C	TSRO	Employee Stock Option (right to buy)	M - Exercise	D	33,74		-3.500		21.500
2016-03-14	2016-03-10	4	English Edward C	TSRO	Common Stock, par value $.01	S - Sale	D		44,1100	-4.500	-198		0
2016-03-14	2016-03-10	4	English Edward C	TSRO	Common Stock, par value $.01	S - Sale	D		42,9800	-2.500	-107		4.500
2016-03-14	2016-03-10	4	English Edward C	TSRO	Common Stock, par value $.01	M - Exercise	D		33,7400	3.500	118		7.000
2016-03-14	2016-03-10	4	English Edward C	TSRO	Common Stock, par value $.01	M - Exercise	D		13,3100	3.500	47		3.500
2016-03-03	2016-03-01	4	MOULDER LEON O JR	TSRO	Employee Stock Option (right to buy)	A - Award	D	43,39		100.000		100.000
2016-03-03	2016-03-01	4	MOULDER LEON O JR	TSRO	Restricted Stock Units	A - Award	D			50.000		50.000
2016-03-03	2016-03-01	4	Hedley Mary Lynne	TSRO	Employee Stock Option (right to buy)	A - Award	D	43,39		80.000		80.000
2016-03-03	2016-03-01	4	Hedley Mary Lynne	TSRO	Restricted Stock Units	A - Award	D			40.000		40.000
2016-03-03	2016-03-01	4	Farmer Joseph L	TSRO	Employee Stock Option (right to buy)	A - Award	D	43,39		35.000		35.000
2016-03-03	2016-03-01	4	Farmer Joseph L	TSRO	Restricted Stock Units	A - Award	D			17.500		17.500
2016-03-03	2016-03-01	4	English Edward C	TSRO	Employee Stock Option (right to buy)	A - Award	D	43,39		13.000		13.000
2016-03-03	2016-03-01	4	English Edward C	TSRO	Restricted Stock Units	A - Award	D			2.500		2.500
2016-03-03	2016-03-01	4	PEARSON TIMOTHY R	TSRO	Employee Stock Option (right to buy)	A - Award	D	43,39		35.000		35.000
2016-03-03	2016-03-01	4	PEARSON TIMOTHY R	TSRO	Restricted Stock Units	A - Award	D			17.500		17.500
2016-03-03	2016-03-01	4	Hanke Jeffrey H.	TSRO	Employee Stock Option (right to buy)	A - Award	D	43,39		35.000		35.000
2016-03-03	2016-03-01	4	Hanke Jeffrey H.	TSRO	Restricted Stock Units	A - Award	D			17.500		17.500
2016-03-03	2016-03-01	4	Bogle Grant C.	TSRO	Employee Stock Option (right to buy)	A - Award	D	43,39		35.000		35.000
2016-03-03	2016-03-01	4	Bogle Grant C.	TSRO	Restricted Stock Units	A - Award	D			17.500		17.500
2016-03-03	2016-03-01	4	Huber Martin H. Jr.	TSRO	Employee Stock Option (right to buy)	A - Award	D	43,39		35.000		35.000
2016-03-03	2016-03-01	4	Huber Martin H. Jr.	TSRO	Restricted Stock Units	A - Award	D			17.500		17.500
2016-02-17	2015-12-16	4	SEIDENBERG BETH C	TSRO	Common Stock	J - Other	D			315			20.388
2016-02-17	2015-12-16	4	SEIDENBERG BETH C	TSRO	Common Stock	J - Other	I			-8.652			1.376.237
2015-12-14	2015-12-10	4	English Edward C	TSRO	Employee Stock Option (right to buy)	M - Exercise	D	34,58		-5.000		10.000
2015-12-14	2015-12-10	4	English Edward C	TSRO	Employee Stock Option (right to buy)	M - Exercise	D	13,31		-12.000		16.572
2015-12-14	2015-12-10	4	English Edward C	TSRO	Common Stock, par value $.01	S - Sale	D		50,1900	-16.950	-851		0
2015-12-14	2015-12-10	4	English Edward C	TSRO	Common Stock, par value $.01	S - Sale	D		49,5200	-50	-2		16.950
2015-12-14	2015-12-10	4	English Edward C	TSRO	Common Stock, par value $.01	M - Exercise	D		34,5800	5.000	173		17.000
2015-12-14	2015-12-10	4	English Edward C	TSRO	Common Stock, par value $.01	M - Exercise	D		13,3100	12.000	160		12.000
2015-09-22	2015-09-21	4	Huber Martin H. Jr.	TSRO	Employee Stock Option (right to buy)	A - Award	D	55,14		75.000		75.000
2015-09-22	2015-09-21	4	Huber Martin H. Jr.	TSRO	Restricted Stock Units	A - Award	D			5.000		5.000
2015-09-21	2015-09-17	4	SEIDENBERG BETH C	TSRO	Common Stock	J - Other	I			-23.400			116.428
2015-09-21	2015-09-17	4	SEIDENBERG BETH C By Samuel B. Seidenberg Irrevocable Trust	TSRO	Common Stock	J - Other	I			205			205
2015-09-21	2015-09-17	4	SEIDENBERG BETH C By Michael J. Seidenberg Irrevocable Trust	TSRO	Common Stock	J - Other	I			205			205
2015-09-21	2015-09-17	4	SEIDENBERG BETH C	TSRO	Common Stock	J - Other	D			3.562			20.073
2015-09-21	2015-09-17	4	SEIDENBERG BETH C	TSRO	Common Stock	J - Other	I			-267.948			1.384.889
2015-09-09	2015-09-08	4	Armitage James O By The Nancy E. Armitage Revocable Living Trust	TSRO	Common Stock	P - Purchase	I		54,6320	500	27		1.500
2015-07-14	2015-07-13	4	Bogle Grant C.	TSRO	Employee Stock Option (right to buy)	A - Award	D	59,71		75.000		75.000
2015-06-29	2015-06-29	4	Hanke Jeffrey H.	TSRO	Employee Stock Option (right to buy)	A - Award	D	56,52		100.000		100.000
2015-06-29	2015-06-29	4	Hanke Jeffrey H.	TSRO	Restricted Stock Units	A - Award	D			50.000		50.000
2015-06-15	2015-06-15	4	Viswanathan Ravi See Note 2	TSRO	Common Stock	S - Sale	I		54,9594	-553	-30		0
2015-06-15	2015-06-12	4	Viswanathan Ravi See Note 2	TSRO	Common Stock	S - Sale	I		54,5340	-336	-18		553
2015-06-04	2015-06-02	4	BASKETT FOREST See Note 3	TSRO	Common Stock	S - Sale	I		58,1299	-629	-37		0
2015-06-04	2015-06-02	4	BASKETT FOREST See Note 3	TSRO	Common Stock	S - Sale	I		57,5549	-1.500	-86		629
2015-06-04	2015-06-02	4	BASKETT FOREST See Note 2	TSRO	Common Stock	S - Sale	I		57,5238	-433	-25		0
2015-06-04	2015-06-03	4	KOLLURI KRISHNA KITTU See Note 3	TSRO	Common Stock	S - Sale	I		58,4300	-110	-6		0
2015-06-04	2015-06-03	4	KOLLURI KRISHNA KITTU See Note 2	TSRO	Common Stock	S - Sale	I		58,3814	-110	-6		0
2015-06-04	2015-06-02	4	KOLLURI KRISHNA KITTU See Note 3	TSRO	Common Stock	S - Sale	I		59,7200	-64	-4		8.854.740
2015-06-04	2015-06-02	4	KOLLURI KRISHNA KITTU See Note 2	TSRO	Common Stock	S - Sale	I		59,7200	-64	-4		110
2015-06-04	2015-06-02	4	SANDELL SCOTT D See Note 3	TSRO	Common Stock	S - Sale	I		58,1299	-629	-37		0
2015-06-04	2015-06-02	4	SANDELL SCOTT D See Note 3	TSRO	Common Stock	S - Sale	I		57,5549	-1.500	-86		629
2015-06-04	2015-06-02	4	SANDELL SCOTT D See Note 2	TSRO	Common Stock	S - Sale	I		59,7200	-504	-30		0
2015-06-04	2015-06-03	4	Weller Harry R See Note 3	TSRO	Common Stock	S - Sale	I		58,7840	-19	-1		0
2015-06-04	2015-06-03	4	Weller Harry R See Note 4	TSRO	Common Stock	S - Sale	I		58,7840	-19	-1		0
2015-06-04	2015-06-03	4	Weller Harry R See Note 2	TSRO	Common Stock	S - Sale	I		58,7840	-340	-20		0
2015-06-04	2015-06-02	4	BARRIS PETER J See Note 5	TSRO	Common Stock	S - Sale	I		58,1299	-629	-37		0
2015-06-04	2015-06-02	4	BARRIS PETER J See Note 5	TSRO	Common Stock	S - Sale	I		57,5549	-1.500	-86		629
2015-06-04	2015-06-02	4	BARRETT M JAMES See Note 3	TSRO	Common Stock	S - Sale	I		58,1299	-629	-37		0
2015-06-04	2015-06-02	4	BARRETT M JAMES See Note 3	TSRO	Common Stock	S - Sale	I		57,5549	-1.500	-86		629
2015-06-03	2015-06-01	4	Armitage James O	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	60,77		10.000		10.000
2015-06-03	2015-06-01	4	COLLIER EARL M JR	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	60,77		10.000		10.000
2015-06-03	2015-06-01	4	ORONSKY ARNOLD L	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	60,77		10.000		10.000
2015-06-03	2015-06-01	4	ORONSKY ARNOLD L	TSRO	Common Stock	A - Award	D			1.003			10.096
2015-06-03	2015-06-01	4	SEIDENBERG BETH C	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	60,77		10.000		10.000
2015-06-03	2015-06-01	4	SEIDENBERG BETH C	TSRO	Common Stock	A - Award	D			946			16.511
2015-06-03	2015-06-01	4	Alleva Lawrence M	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	60,77		10.000		10.000
2015-06-03	2015-06-01	4	Alleva Lawrence M	TSRO	Common Stock	A - Award	D			1.069			26.354
2015-06-03	2015-06-01	4	Nicholson Garry A	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	60,77		25.000		25.000
2015-06-02	2015-06-01	4	NEW ENTERPRISE ASSOCIATES 13 LP	TSRO	Common Stock	J - Other	D			-1.000.000			8.854.255
2015-06-02	2015-06-01	4	NEA Partners 13, Limited Partnership	TSRO	Common Stock	J - Other	D			-10.000			0
2015-06-02	2015-06-01	4	NEA Partners 13, Limited Partnership	TSRO	Common Stock	J - Other	D			10.000			10.000
2015-06-02	2015-06-01	4	NEA Partners 13, Limited Partnership See Note 2	TSRO	Common Stock	J - Other	I			-1.000.000			8.854.255
2015-06-02	2015-06-01	4	BARRETT M JAMES See Note 10	TSRO	Common Stock	J - Other	I			252			252
2015-06-02	2015-06-01	4	BARRETT M JAMES	TSRO	Common Stock	J - Other	D			252			252
2015-06-02	2015-06-01	4	BARRETT M JAMES See Note 8	TSRO	Common Stock	J - Other	I			2.129			2.129
2015-06-02	2015-06-01	4	BARRETT M JAMES See Note 4	TSRO	Common Stock	J - Other	I			-10.000			0
2015-06-02	2015-06-01	4	BARRETT M JAMES See Note 4	TSRO	Common Stock	J - Other	I			10.000			10.000
2015-06-02	2015-06-01	4	BARRETT M JAMES See Note 2	TSRO	Common Stock	J - Other	I			-1.000.000			8.854.255
2015-06-02	2015-06-01	4	MOTT DAVID M	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	60,77		10.000		10.000
2015-06-02	2015-06-01	4	MOTT DAVID M See Note 8	TSRO	Common Stock	J - Other	I			504			1.333
2015-06-02	2015-06-01	4	MOTT DAVID M	TSRO	Common Stock	A - Award	D			1.357			10.034
2015-06-02	2015-06-01	4	MOTT DAVID M See Note 4	TSRO	Common Stock	J - Other	I			-10.000			0
2015-06-02	2015-06-01	4	MOTT DAVID M See Note 4	TSRO	Common Stock	J - Other	I			10.000			10.000
2015-06-02	2015-06-01	4	MOTT DAVID M See Note 2	TSRO	Common Stock	J - Other	I			-1.000.000			8.854.255
2015-06-02	2015-06-01	4	BARRIS PETER J See Note 11	TSRO	Common Stock	J - Other	I			2.129			2.129
2015-06-02	2015-06-01	4	BARRIS PETER J See Note 9	TSRO	Common Stock	J - Other	I			290			767
2015-06-02	2015-06-01	4	BARRIS PETER J See Note 7	TSRO	Common Stock	J - Other	I			290			767
2015-06-02	2015-06-01	4	BARRIS PETER J See Note 4	TSRO	Common Stock	J - Other	I			-10.000			0
2015-06-02	2015-06-01	4	BARRIS PETER J See Note 4	TSRO	Common Stock	J - Other	I			10.000			10.000
2015-06-02	2015-06-01	4	BARRIS PETER J See Note 2	TSRO	Common Stock	J - Other	I			-1.000.000			8.854.255
2015-06-02	2015-06-01	4	DRANT RYAN D See Note 8	TSRO	Common Stock	J - Other	I			151			151
2015-06-02	2015-06-01	4	DRANT RYAN D	TSRO	Common Stock	J - Other	D			353			353
2015-06-02	2015-06-01	4	DRANT RYAN D See Note 4	TSRO	Common Stock	J - Other	I			-10.000			0
2015-06-02	2015-06-01	4	DRANT RYAN D See Note 4	TSRO	Common Stock	J - Other	I			10.000			10.000
2015-06-02	2015-06-01	4	DRANT RYAN D See Note 2	TSRO	Common Stock	J - Other	I			-1.000.000			8.854.255
2015-06-02	2015-06-01	4	KERINS PATRICK J	TSRO	Common Stock	J - Other	D			504			1.333
2015-06-02	2015-06-01	4	KERINS PATRICK J See Note 4	TSRO	Common Stock	J - Other	I			-10.000			0
2015-06-02	2015-06-01	4	KERINS PATRICK J See Note 4	TSRO	Common Stock	J - Other	I			10.000			10.000
2015-06-02	2015-06-01	4	KERINS PATRICK J See Note 2	TSRO	Common Stock	J - Other	I			-1.000.000			8.854.255
2015-06-02	2015-06-01	4	KOLLURI KRISHNA KITTU See Note 9	TSRO	Common Stock	J - Other	I			64			174
2015-06-02	2015-06-01	4	KOLLURI KRISHNA KITTU See Note 11	TSRO	Common Stock	J - Other	I			64			174
2015-06-02	2015-06-01	4	KOLLURI KRISHNA KITTU See Note 7	TSRO	Common Stock	J - Other	I			375			375
2015-06-02	2015-06-01	4	KOLLURI KRISHNA KITTU See Note 4	TSRO	Common Stock	J - Other	I			-10.000			0
2015-06-02	2015-06-01	4	KOLLURI KRISHNA KITTU See Note 4	TSRO	Common Stock	J - Other	I			10.000			10.000
2015-06-02	2015-06-01	4	KOLLURI KRISHNA KITTU See Note 2	TSRO	Common Stock	J - Other	I			-1.000.000			8.854.255
2015-06-02	2015-06-01	4	SANDELL SCOTT D See Note 9	TSRO	Common Stock	J - Other	I			2.129			2.129
2015-06-02	2015-06-01	4	SANDELL SCOTT D See Note 7	TSRO	Common Stock	J - Other	I			504			504
2015-06-02	2015-06-01	4	SANDELL SCOTT D See Note 4	TSRO	Common Stock	J - Other	I			-10.000			0
2015-06-02	2015-06-01	4	SANDELL SCOTT D See Note 4	TSRO	Common Stock	J - Other	I			10.000			10.000
2015-06-02	2015-06-01	4	SANDELL SCOTT D See Note 2	TSRO	Common Stock	J - Other	I			-1.000.000			8.854.255
2015-06-02	2015-06-01	4	Viswanathan Ravi See Note 7	TSRO	Common Stock	J - Other	I			336			889
2015-06-02	2015-06-01	4	Viswanathan Ravi See Note 4	TSRO	Common Stock	J - Other	I			-10.000			0
2015-06-02	2015-06-01	4	Viswanathan Ravi See Note 4	TSRO	Common Stock	J - Other	I			10.000			10.000
2015-06-02	2015-06-01	4	Viswanathan Ravi See Note 2	TSRO	Common Stock	J - Other	I			-1.000.000			8.854.255
2015-06-02	2015-06-01	4	Weller Harry R See Note 9	TSRO	Common Stock	J - Other	I			19			19
2015-06-02	2015-06-01	4	Weller Harry R See Note 11	TSRO	Common Stock	J - Other	I			19			19
2015-06-02	2015-06-01	4	Weller Harry R See Note 7	TSRO	Common Stock	J - Other	I			340			340
2015-06-02	2015-06-01	4	Weller Harry R See Note 4	TSRO	Common Stock	J - Other	I			-10.000			0
2015-06-02	2015-06-01	4	Weller Harry R See Note 4	TSRO	Common Stock	J - Other	I			10.000			10.000
2015-06-02	2015-06-01	4	Weller Harry R See Note 2	TSRO	Common Stock	J - Other	I			-1.000.000			8.854.255
2015-06-02	2015-06-01	4	BASKETT FOREST See Note 9	TSRO	Common Stock	J - Other	I			2.129			2.129
2015-06-02	2015-06-01	4	BASKETT FOREST See Note 7	TSRO	Common Stock	J - Other	I			433			433
2015-06-02	2015-06-01	4	BASKETT FOREST See Note 4	TSRO	Common Stock	J - Other	I			-10.000			0
2015-06-02	2015-06-01	4	BASKETT FOREST See Note 4	TSRO	Common Stock	J - Other	I			10.000			10.000
2015-06-02	2015-06-01	4	BASKETT FOREST See Note 2	TSRO	Common Stock	J - Other	I			-1.000.000			8.854.255
2015-04-01	2015-03-30	4	Farmer Joseph L	TSRO	Employee Stock Option (right to buy)	A - Award	D	57,66		75.000		75.000
2015-03-10	2015-03-06	4	PEARSON TIMOTHY R	TSRO	Employee Stock Option (right to buy)	A - Award	D	55,11		55.000		55.000
2015-03-10	2015-03-06	4	Hedley Mary Lynne	TSRO	Employee Stock Option (right to buy)	A - Award	D	55,11		115.000
2015-03-10	2015-03-06	4	MOULDER LEON O JR	TSRO	Employee Stock Option (right to buy)	A - Award	D	55,11		140.000		140.000
2015-03-10	2015-03-06	4	English Edward C	TSRO	Employee Stock Option (right to buy)	A - Award	D	55,11		25.000		25.000
2015-01-14	2015-01-12	4	ORONSKY ARNOLD L	TSRO	Common Stock	J - Other	D			1.263			9.093
2015-01-14	2015-01-12	4	ORONSKY ARNOLD L By InterWest Management Partners X, LLC	TSRO	Common Stock	J - Other	I			-6.000			0
2015-01-14	2015-01-12	4	ORONSKY ARNOLD L By InterWest Management Partners X, LLC	TSRO	Common Stock	J - Other	I			6.000			6.000
2015-01-14	2015-01-12	4	ORONSKY ARNOLD L By InterWest Partners X, LP	TSRO	Common Stock	J - Other	I			-600.000			1.871.701
2014-12-15	2014-12-12	4	Armitage James O By The Nancy E. Armitage Revocable Living Trust	TSRO	Common Stock	P - Purchase	I		38,1550	1.000	38		1.000
2014-09-30	2014-09-29	4	Alleva Lawrence M	TSRO	Common Stock	P - Purchase	D		26,1700	1.100	29		25.285
2014-06-04	2014-06-02	4	ORONSKY ARNOLD L	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	26,36		10.000		10.000
2014-06-04	2014-06-02	4	ORONSKY ARNOLD L	TSRO	Common Stock	A - Award	D			2.371			7.830
2014-06-04	2014-06-02	4	COLLIER EARL M JR	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	26,36		25.000		25.000
2014-06-04	2014-06-02	4	Armitage James O	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	26,36		10.000		10.000
2014-06-04	2014-06-02	4	SEIDENBERG BETH C	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	26,36		10.000		10.000
2014-06-04	2014-06-02	4	SEIDENBERG BETH C	TSRO	Common Stock	A - Award	D			2.238			15.565
2014-06-04	2014-06-02	4	MOTT DAVID M	TSRO	Employee Stock Option (right to buy)	A - Award	D	26,36		10.000		10.000
2014-06-04	2014-06-02	4	MOTT DAVID M	TSRO	Common Stock	A - Award	D			3.186			8.677
2014-06-04	2014-06-02	4	Alleva Lawrence M	TSRO	Director Nonqualified Stock Option (right to buy)	A - Award	D	26,36		10.000		10.000
2014-06-04	2014-06-02	4	Alleva Lawrence M	TSRO	Common Stock	A - Award	D			2.522			24.185
2014-06-04	2014-06-02	4	Walker Paul Edward	TSRO	Common Stock	A - Award	D			94			4.041
2014-05-29	2014-05-27	4	PEARSON TIMOTHY R	TSRO	Employee Stock Option (right to buy)	A - Award	D	25,27		125.000		125.000
2014-05-09	2014-05-08	4	English Edward C	TSRO	Employee Stock Option (right to buy)	A - Award	D	22,78		10.000		10.000
2014-03-07	2014-02-27	4/A	Hedley Mary Lynne	TSRO	Employee Stock Option (right to buy)	A - Award	D	33,74		105.000		105.000
2014-03-07	2014-02-27	4/A	English Edward C	TSRO	Employee Stock Option (right to buy)	A - Award	D	33,74		25.000		25.000
2014-03-07	2014-02-27	4/A	MOULDER LEON O JR	TSRO	Employee Stock Option (right to buy)	A - Award	D	33,74		125.000		125.000
2014-03-04	2014-02-27	4	MOULDER LEON O JR	TSRO	Employee Stock Option (right to buy)	A - Award	D	33,74		125.000		325.000
2014-03-04	2014-02-27	4	English Edward C	TSRO	Employee Stock Option (right to buy)	A - Award	D	33,74		25.000		93.572
2014-03-04	2014-02-27	4	Hedley Mary Lynne	TSRO	Employee Stock Option (right to buy)	A - Award	D	33,74		105.000		280.000
2013-09-04	2013-08-30	4	English Edward C	TSRO	Employee Stock Option (right to buy)	A - Award	D	34,58		15.000		68.572
2013-08-07	2013-08-05	4	INTERWEST PARTNERS X LP	TSRO	Common Stock	J - Other	D			-600.000			2.471.701
2013-08-07	2013-08-05	4	InterWest Management Partners X, LLC	TSRO	Common Stock	J - Other	D			-600.000			2.471.701
2013-08-06	2013-08-05	4	ORONSKY ARNOLD L	TSRO	Common Stock	J - Other	D			1.216			5.459
2013-08-06	2013-08-05	4	ORONSKY ARNOLD L By partnership	TSRO	Common Stock	J - Other	I			-600.000			2.471.701
2013-08-01	2013-07-31	4	Alleva Lawrence M	TSRO	Common Stock	P - Purchase	D		34,3300	1.449	50		21.663
2013-07-25	2013-06-27	4	KOLLURI KRISHNA KITTU See Note 1	TSRO	Common Stock	G - Gift	I			-610			0
2013-06-11	2013-06-10	4	BARRETT M JAMES	TSRO	Common Stock	S - Sale	D		40,4888	-415	-17		0
2013-06-11	2013-06-10	4	Weller Harry R See Note 2	TSRO	Common Stock	S - Sale	I		41,4476	-560	-23		0
2013-06-05	2013-06-03	4	SEIDENBERG BETH C	TSRO	Employee Stock Option (right to buy)	A - Award	D	46,22		10.000
2013-06-05	2013-06-03	4	SEIDENBERG BETH C	TSRO	Common Stock	A - Award	D			1.006			13.327
2013-06-05	2013-06-03	4	ORONSKY ARNOLD L	TSRO	Employee Stock Option (right to buy)	A - Award	D	46,22		10.000		10.000
2013-06-05	2013-06-03	4	ORONSKY ARNOLD L	TSRO	Common Stock	A - Award	D			1.081			4.243
2013-06-05	2013-06-03	4	Armitage James O	TSRO	Employee Stock Option (right to buy)	A - Award	D	46,22		25.000		25.000
2013-06-05	2013-06-04	4	NEW ENTERPRISE ASSOCIATES 13 LP	TSRO	Common Stock	J - Other	D			-1.645.000			9.854.255
2013-06-05	2013-06-04	4	NEA Partners 13, Limited Partnership	TSRO	Common Stock	J - Other	D			-16.450			0
2013-06-05	2013-06-04	4	NEA Partners 13, Limited Partnership	TSRO	Common Stock	J - Other	D			16.450			16.450
2013-06-05	2013-06-04	4	NEA Partners 13, Limited Partnership See Note 2	TSRO	Common Stock	J - Other	I			-1.645.000			9.854.255
2013-06-05	2013-06-05	4	BARRIS PETER J See Note 11	TSRO	Common Stock	S - Sale	I		38,9968	-3.583	-140		0
2013-06-05	2013-06-04	4	BARRIS PETER J See Note 11	TSRO	Common Stock	J - Other	I			3.583			3.583
2013-06-05	2013-06-04	4	BARRIS PETER J See Note 9	TSRO	Common Stock	J - Other	I			477			477
2013-06-05	2013-06-04	4	BARRIS PETER J See Note 7	TSRO	Common Stock	J - Other	I			477			477
2013-06-05	2013-06-04	4	BARRIS PETER J See Note 4	TSRO	Common Stock	J - Other	I			-16.450			0
2013-06-05	2013-06-04	4	BARRIS PETER J See Note 4	TSRO	Common Stock	J - Other	I			16.450			16.450
2013-06-05	2013-06-04	4	BARRIS PETER J See Note 2	TSRO	Common Stock	J - Other	I			-1.645.000			9.854.255
2013-06-05	2013-06-05	4	BARRETT M JAMES See Note 8	TSRO	Common Stock	S - Sale	I		38,9968	-3.583	-140		0
2013-06-05	2013-06-04	4	BARRETT M JAMES See Note 8	TSRO	Common Stock	J - Other	I			3.583			3.583
2013-06-05	2013-06-04	4	BARRETT M JAMES	TSRO	Common Stock	J - Other	D			415			415
2013-06-05	2013-06-04	4	BARRETT M JAMES See Note 4	TSRO	Common Stock	J - Other	I			-16.450			0
2013-06-05	2013-06-04	4	BARRETT M JAMES See Note 4	TSRO	Common Stock	J - Other	I			16.450			16.450
2013-06-05	2013-06-04	4	BARRETT M JAMES See Note 2	TSRO	Common Stock	J - Other	I			-1.645.000			9.854.255
2013-06-05	2013-06-05	4	DRANT RYAN D	TSRO	Common Stock	S - Sale	D		40,1699	-580	-23		0
2013-06-05	2013-06-05	4	DRANT RYAN D See Note 8	TSRO	Common Stock	S - Sale	I		38,9968	-3.583	-140		0
2013-06-05	2013-06-04	4	DRANT RYAN D See Note 8	TSRO	Common Stock	J - Other	I			3.583			3.583
2013-06-05	2013-06-04	4	DRANT RYAN D	TSRO	Common Stock	J - Other	D			580			580
2013-06-05	2013-06-04	4	DRANT RYAN D See Note 4	TSRO	Common Stock	J - Other	I			-16.450			0
2013-06-05	2013-06-04	4	DRANT RYAN D See Note 4	TSRO	Common Stock	J - Other	I			16.450			16.450
2013-06-05	2013-06-04	4	DRANT RYAN D See Note 2	TSRO	Common Stock	J - Other	I			-1.645.000			9.854.255
2013-06-05	2013-06-04	4	MOTT DAVID M See Note 8	TSRO	Common Stock	J - Other	I			829			829
2013-06-05	2013-06-04	4	MOTT DAVID M See Note 4	TSRO	Common Stock	J - Other	I			-16.450			0
2013-06-05	2013-06-04	4	MOTT DAVID M See Note 4	TSRO	Common Stock	J - Other	I			16.450			16.450
2013-06-05	2013-06-04	4	MOTT DAVID M See Note 2	TSRO	Common Stock	J - Other	I			-1.645.000			9.854.255
2013-06-05	2013-06-03	4	MOTT DAVID M	TSRO	Employee Stock Option (right to buy)	A - Award	D	46,22		10.000		10.000
2013-06-05	2013-06-03	4	MOTT DAVID M	TSRO	Common Stock	A - Award	D			1.330			5.491
2013-06-05	2013-06-04	4	KERINS PATRICK J	TSRO	Common Stock	J - Other	D			829			829
2013-06-05	2013-06-04	4	KERINS PATRICK J See Note 4	TSRO	Common Stock	J - Other	I			-16.450			0
2013-06-05	2013-06-04	4	KERINS PATRICK J See Note 4	TSRO	Common Stock	J - Other	I			16.450			16.450
2013-06-05	2013-06-04	4	KERINS PATRICK J See Note 2	TSRO	Common Stock	J - Other	I			-1.645.000			9.854.255
2013-06-05	2013-06-04	4	KOLLURI KRISHNA KITTU See Note 11	TSRO	Common Stock	J - Other	I			110			110
2013-06-05	2013-06-04	4	KOLLURI KRISHNA KITTU See Note 9	TSRO	Common Stock	J - Other	I			110			110
2013-06-05	2013-06-04	4	KOLLURI KRISHNA KITTU See Note 7	TSRO	Common Stock	J - Other	I			610			610
2013-06-05	2013-06-04	4	KOLLURI KRISHNA KITTU See Note 4	TSRO	Common Stock	J - Other	I			-16.450			0
2013-06-05	2013-06-04	4	KOLLURI KRISHNA KITTU See Note 4	TSRO	Common Stock	J - Other	I			16.450			16.450
2013-06-05	2013-06-04	4	KOLLURI KRISHNA KITTU See Note 2	TSRO	Common Stock	J - Other	I			-1.645.000			9.854.255
2013-06-05	2013-06-05	4	SANDELL SCOTT D See Note 7	TSRO	Common Stock	S - Sale	I		40,6700	-829	-34		0
2013-06-05	2013-06-05	4	SANDELL SCOTT D See Note 9	TSRO	Common Stock	S - Sale	I		38,9968	-3.583	-140		0
2013-06-05	2013-06-04	4	SANDELL SCOTT D See Note 9	TSRO	Common Stock	J - Other	I			3.583			3.583
2013-06-05	2013-06-04	4	SANDELL SCOTT D See Note 7	TSRO	Common Stock	J - Other	I			829			829
2013-06-05	2013-06-04	4	SANDELL SCOTT D See Note 4	TSRO	Common Stock	J - Other	I			-16.450			0
2013-06-05	2013-06-04	4	SANDELL SCOTT D See Note 4	TSRO	Common Stock	J - Other	I			16.450			16.450
2013-06-05	2013-06-04	4	SANDELL SCOTT D See Note 2	TSRO	Common Stock	J - Other	I			-1.645.000			9.854.255
2013-06-05	2013-06-04	4	Viswanathan Ravi See Note 7	TSRO	Common Stock	J - Other	I			553			553
2013-06-05	2013-06-04	4	Viswanathan Ravi See Note 4	TSRO	Common Stock	J - Other	I			-16.450			0
2013-06-05	2013-06-04	4	Viswanathan Ravi See Note 4	TSRO	Common Stock	J - Other	I			16.450			16.450
2013-06-05	2013-06-04	4	Viswanathan Ravi See Note 2	TSRO	Common Stock	J - Other	I			-1.645.000			9.854.255
2013-06-05	2013-06-05	4	BASKETT FOREST See Note 7	TSRO	Common Stock	S - Sale	I		39,8900	-713	-28		0
2013-06-05	2013-06-05	4	BASKETT FOREST See Note 9	TSRO	Common Stock	S - Sale	I		38,9968	-3.583	-140		0
2013-06-05	2013-06-04	4	BASKETT FOREST See Note 9	TSRO	Common Stock	J - Other	I			3.583			3.583
2013-06-05	2013-06-04	4	BASKETT FOREST See Note 7	TSRO	Common Stock	J - Other	I			713			713
2013-06-05	2013-06-04	4	BASKETT FOREST See Note 4	TSRO	Common Stock	J - Other	I			-16.450			0
2013-06-05	2013-06-04	4	BASKETT FOREST See Note 4	TSRO	Common Stock	J - Other	I			16.450			16.450
2013-06-05	2013-06-04	4	BASKETT FOREST See Note 2	TSRO	Common Stock	J - Other	I			-1.645.000			9.854.255
2013-06-05	2013-06-04	4	Weller Harry R See Note 7	TSRO	Common Stock	J - Other	I			560			560
2013-06-05	2013-06-04	4	Weller Harry R See Note 4	TSRO	Common Stock	J - Other	I			-16.450			0
2013-06-05	2013-06-04	4	Weller Harry R See Note 4	TSRO	Common Stock	J - Other	I			16.450			16.450
2013-06-05	2013-06-04	4	Weller Harry R See Note 2	TSRO	Common Stock	J - Other	I			-1.645.000			9.854.255
2013-06-05	2013-06-03	4	Alleva Lawrence M	TSRO	Employee Stock Option (right to buy)	A - Award	D	46,22		10.000		10.000
2013-06-05	2013-06-03	4	Alleva Lawrence M	TSRO	Common Stock	A - Award	D			1.114			20.214
2013-06-05	2013-06-03	4	Walker Paul Edward	TSRO	Employee Stock Option (right to buy)	A - Award	D	46,22		10.000		10.000
2013-06-05	2013-06-03	4	Walker Paul Edward	TSRO	Common Stock	A - Award	D			951			3.947
2013-05-29	2013-05-28	4	SEIDENBERG BETH C	TSRO	Common Stock	J - Other	D			9.325			12.321
2013-05-02	2013-04-30	4	Alleva Lawrence M	TSRO	Common Stock	P - Purchase	D		28,1000	1.050	30		19.100
2013-03-08	2013-03-06	4	English Edward C	TSRO	Employee Stock Option (right to buy)	A - Award	D	24,18		25.000		25.000
2013-03-08	2013-03-06	4	Rodgers Richard J	TSRO	Employee Stock Option (right to buy)	A - Award	D	24,18		65.000		65.000
2013-03-08	2013-03-06	4	Hedley Mary Lynne	TSRO	Employee Stock Option (right to buy)	A - Award	D	24,18		175.000		175.000
2013-03-08	2013-03-06	4	MOULDER LEON O JR	TSRO	Employee Stock Option (right to buy)	A - Award	D	24,18		200.000		200.000
2012-11-02	2012-11-01	4	Alleva Lawrence M	TSRO	Common Stock	P - Purchase	D		15,4500	3.240	50		18.050
2012-10-17	2012-10-15	4	SEIDENBERG BETH C	TSRO	Common Stock	A - Award	D			2.996			2.996
2012-10-17	2012-10-15	4	ORONSKY ARNOLD L	TSRO	Common Stock	A - Award	D			3.162			3.162
2012-10-17	2012-10-15	4	MOTT DAVID M	TSRO	Common Stock	A - Award	D			4.161			4.161
2012-10-17	2012-10-15	4	Alleva Lawrence M	TSRO	Common Stock	A - Award	D			3.329			14.810
2012-10-17	2012-10-15	4	Walker Paul Edward	TSRO	Common Stock	A - Award	D			2.996			2.996
2012-08-31	2012-08-30	4	MOULDER LEON O JR	TSRO	Common Stock	P - Purchase	D		11,6900	10.000	117		1.006.428
2012-07-06	2012-07-03	4	Hedley Mary Lynne	TSRO	Series A Preferred Stock	C - Conversion	D			-250.000		0
2012-07-06	2012-07-03	4	Hedley Mary Lynne	TSRO	Common Stock	C - Conversion	D			71.428			563.569
2012-07-06	2012-07-03	4	MOULDER LEON O JR	TSRO	Series A Preferred Stock	C - Conversion	D			-1.500.000		0
2012-07-06	2012-07-03	4	MOULDER LEON O JR	TSRO	Common Stock	C - Conversion	D			428.571			996.428
2012-07-06	2012-07-03	4	ORONSKY ARNOLD L	TSRO	Series B Preferred Stock	C - Conversion	I			-9.195.402		0
2012-07-06	2012-07-03	4	ORONSKY ARNOLD L	TSRO	Common Stock	P - Purchase	I		13,5000	444.444	6.000		3.071.701
2012-07-06	2012-07-03	4	ORONSKY ARNOLD L	TSRO	Common Stock	C - Conversion	I			2.627.257			2.627.257
2012-07-06	2012-07-03	4	Rodgers Richard J	TSRO	Series A Preferred Stock	C - Conversion	D			-250.000		0
2012-07-06	2012-07-03	4	Rodgers Richard J	TSRO	Common Stock	C - Conversion	D			71.428			257.141
2012-07-06	2012-07-03	4	SEIDENBERG BETH C	TSRO	Series B Preferred Stock	C - Conversion	I			-537.932		0
2012-07-06	2012-07-03	4	SEIDENBERG BETH C	TSRO	Series B Preferred Stock	C - Conversion	I			-6.358.619		0
2012-07-06	2012-07-03	4	SEIDENBERG BETH C	TSRO	Common Stock	P - Purchase	I		13,5000	17.333	234		171.028
2012-07-06	2012-07-03	4	SEIDENBERG BETH C	TSRO	Common Stock	P - Purchase	I		13,5000	204.889	2.766		2.021.637
2012-07-06	2012-07-03	4	SEIDENBERG BETH C	TSRO	Common Stock	C - Conversion	I			153.695			153.695
2012-07-06	2012-07-03	4	SEIDENBERG BETH C	TSRO	Common Stock	C - Conversion	I			1.816.748			1.816.748
2012-07-06	2012-07-03	4	Alleva Lawrence M	TSRO	Common Stock	P - Purchase	D		13,5000	11.481	155		11.481
2012-07-05	2012-07-03	4	INTERWEST PARTNERS X LP	TSRO	Series B Preferred Stock	C - Conversion	D			-9.195.402		0
2012-07-05	2012-07-03	4	INTERWEST PARTNERS X LP	TSRO	Common Stock	P - Purchase	D		13,5000	444.444	6.000		3.071.701
2012-07-05	2012-07-03	4	INTERWEST PARTNERS X LP	TSRO	Common Stock	C - Conversion	D			2.627.257			2.627.257
2012-07-05	2012-07-03	4	InterWest Management Partners X, LLC	TSRO	Series B Preferred Stock	C - Conversion	D			-9.195.402		0
2012-07-05	2012-07-03	4	InterWest Management Partners X, LLC	TSRO	Common Stock	P - Purchase	D		13,5000	444.444	6.000		3.071.701
2012-07-05	2012-07-03	4	InterWest Management Partners X, LLC	TSRO	Common Stock	C - Conversion	D			2.627.257			2.627.257
2012-07-03	2012-07-03	4	BARRETT M JAMES See Note 2	TSRO	Series B Preferred Stock	C - Conversion	I			-5.253.859		0
2012-07-03	2012-07-03	4	BARRETT M JAMES See Note 2	TSRO	Series A Preferred Stock	C - Conversion	I			-5.134.285		0
2012-07-03	2012-07-03	4	BARRETT M JAMES See Note 2	TSRO	Common Stock	P - Purchase	I		13,5000	1.111.111	15.000		11.499.255
2012-07-03	2012-07-03	4	BARRETT M JAMES See Note 2	TSRO	Common Stock	C - Conversion	I			10.388.144			10.388.144
2012-07-03	2012-07-03	4	MOTT DAVID M See Note 2	TSRO	Series B Preferred Stock	C - Conversion	I			-5.253.859		0
2012-07-03	2012-07-03	4	MOTT DAVID M See Note 2	TSRO	Series A Preferred Stock	C - Conversion	I			-5.134.285		0
2012-07-03	2012-07-03	4	MOTT DAVID M See Note 2	TSRO	Common Stock	P - Purchase	I		13,5000	1.111.111	15.000		11.499.255
2012-07-03	2012-07-03	4	MOTT DAVID M See Note 2	TSRO	Common Stock	C - Conversion	I			10.388.144			10.388.144
2012-07-03	2012-07-03	4	BARRIS PETER J See Note 2	TSRO	Series B Preferred Stock	C - Conversion	I			-5.253.859		0
2012-07-03	2012-07-03	4	BARRIS PETER J See Note 2	TSRO	Series A Preferred Stock	C - Conversion	I			-5.134.285		0
2012-07-03	2012-07-03	4	BARRIS PETER J See Note 2	TSRO	Common Stock	P - Purchase	I		13,5000	1.111.111	15.000		11.499.255
2012-07-03	2012-07-03	4	BARRIS PETER J See Note 2	TSRO	Common Stock	C - Conversion	I			10.388.144			10.388.144
2012-07-03	2012-07-03	4	BASKETT FOREST See Note 2	TSRO	Series B Preferred Stock	C - Conversion	I			-5.253.859		0
2012-07-03	2012-07-03	4	BASKETT FOREST See Note 2	TSRO	Series A Preferred Stock	C - Conversion	I			-5.134.285		0
2012-07-03	2012-07-03	4	BASKETT FOREST See Note 2	TSRO	Common Stock	P - Purchase	I		13,5000	1.111.111	15.000		11.499.255
2012-07-03	2012-07-03	4	BASKETT FOREST See Note 2	TSRO	Common Stock	C - Conversion	I			10.388.144			10.388.144
2012-07-03	2012-07-03	4	DRANT RYAN D See Note 2	TSRO	Series B Preferred Stock	C - Conversion	I			-5.253.859		0
2012-07-03	2012-07-03	4	DRANT RYAN D See Note 2	TSRO	Series A Preferred Stock	C - Conversion	I			-5.134.285		0
2012-07-03	2012-07-03	4	DRANT RYAN D See Note 2	TSRO	Common Stock	P - Purchase	I		13,5000	1.111.111	15.000		11.499.255
2012-07-03	2012-07-03	4	DRANT RYAN D See Note 2	TSRO	Common Stock	C - Conversion	I			10.388.144			10.388.144
2012-07-03	2012-07-03	4	KERINS PATRICK J See Note 2	TSRO	Series B Preferred Stock	C - Conversion	I			-5.253.859		0
2012-07-03	2012-07-03	4	KERINS PATRICK J See Note 2	TSRO	Series A Preferred Stock	C - Conversion	I			-5.134.285		0
2012-07-03	2012-07-03	4	KERINS PATRICK J See Note 2	TSRO	Common Stock	P - Purchase	I		13,5000	1.111.111	15.000		11.499.255
2012-07-03	2012-07-03	4	KERINS PATRICK J See Note 2	TSRO	Common Stock	C - Conversion	I			10.388.144			10.388.144
2012-07-03	2012-07-03	4	KRAMLICH C RICHARD See Note 2	TSRO	Series B Preferred Stock	C - Conversion	I			-5.253.859		0
2012-07-03	2012-07-03	4	KRAMLICH C RICHARD See Note 2	TSRO	Series A Preferred Stock	C - Conversion	I			-5.134.285		0
2012-07-03	2012-07-03	4	KRAMLICH C RICHARD See Note 2	TSRO	Common Stock	P - Purchase	I		13,5000	1.111.111	15.000		11.499.255
2012-07-03	2012-07-03	4	KRAMLICH C RICHARD See Note 2	TSRO	Common Stock	C - Conversion	I			10.388.144			10.388.144
2012-07-03	2012-07-03	4	KOLLURI KRISHNA KITTU See Note 2	TSRO	Series B Preferred Stock	C - Conversion	I			-5.253.859		0
2012-07-03	2012-07-03	4	KOLLURI KRISHNA KITTU See Note 2	TSRO	Series A Preferred Stock	C - Conversion	I			-5.134.285		0
2012-07-03	2012-07-03	4	KOLLURI KRISHNA KITTU See Note 2	TSRO	Common Stock	P - Purchase	I		13,5000	1.111.111	15.000		11.499.255
2012-07-03	2012-07-03	4	KOLLURI KRISHNA KITTU See Note 2	TSRO	Common Stock	C - Conversion	I			10.388.144			10.388.144
2012-07-03	2012-07-03	4	SANDELL SCOTT D See Note 2	TSRO	Series B Preferred Stock	C - Conversion	I			-5.253.859		0
2012-07-03	2012-07-03	4	SANDELL SCOTT D See Note 2	TSRO	Series A Preferred Stock	C - Conversion	I			-5.134.285		0
2012-07-03	2012-07-03	4	SANDELL SCOTT D See Note 2	TSRO	Common Stock	P - Purchase	I		13,5000	1.111.111	15.000		11.499.255
2012-07-03	2012-07-03	4	SANDELL SCOTT D See Note 2	TSRO	Common Stock	C - Conversion	I			10.388.144			10.388.144
2012-07-03	2012-07-03	4	Viswanathan Ravi See Note 2	TSRO	Series B Preferred Stock	C - Conversion	I			-5.253.859		0
2012-07-03	2012-07-03	4	Viswanathan Ravi See Note 2	TSRO	Series A Preferred Stock	C - Conversion	I			-5.134.285		0
2012-07-03	2012-07-03	4	Viswanathan Ravi See Note 2	TSRO	Common Stock	P - Purchase	I		13,5000	1.111.111	15.000		11.499.255
2012-07-03	2012-07-03	4	Viswanathan Ravi See Note 2	TSRO	Common Stock	C - Conversion	I			10.388.144			10.388.144
2012-07-03	2012-07-03	4	Weller Harry R See Note 2	TSRO	Series B Preferred Stock	C - Conversion	I			-5.253.859		0
2012-07-03	2012-07-03	4	Weller Harry R See Note 2	TSRO	Series A Preferred Stock	C - Conversion	I			-5.134.285		0
2012-07-03	2012-07-03	4	Weller Harry R See Note 2	TSRO	Common Stock	P - Purchase	I		13,5000	1.111.111	15.000		11.499.255
2012-07-03	2012-07-03	4	Weller Harry R See Note 2	TSRO	Common Stock	C - Conversion	I			10.388.144			10.388.144
2012-07-03	2012-07-03	4	NEW ENTERPRISE ASSOCIATES 13 LP	TSRO	Series B Preferred Stock	C - Conversion	D			-5.253.859		0
2012-07-03	2012-07-03	4	NEW ENTERPRISE ASSOCIATES 13 LP	TSRO	Series A Preferred Stock	C - Conversion	D			-5.134.285		0
2012-07-03	2012-07-03	4	NEW ENTERPRISE ASSOCIATES 13 LP	TSRO	Common Stock	P - Purchase	D		13,5000	1.111.111	15.000		11.499.255
2012-07-03	2012-07-03	4	NEW ENTERPRISE ASSOCIATES 13 LP	TSRO	Common Stock	C - Conversion	D			10.388.144			10.388.144
2012-06-27		3	Hedley Mary Lynne	TSRO	Common Stock		D						492.141
2012-06-27		3	Rodgers Richard J	TSRO	Common Stock		D						185.713
2012-06-27		3	MOULDER LEON O JR	TSRO	Common Stock		D						567.857

Åbent marked eller privat køb af ikke-afledte eller afledte værdipapirer

Åbent marked eller privat salg af ikke-afledte eller afledte værdipapirer

Tildeling, tildeling eller anden erhvervelse af værdipapirer fra virksomheden (såsom en option)

Konvertering af derivat

Salg eller overførsel af værdipapirer tilbage til virksomheden

Betaling af udnyttelseskurs eller skatteforpligtelse ved brug af en del af værdipapirer modtaget fra selskabet

Gave af værdipapirer af eller til insideren

Aktieswaps og lignende sikringstransaktioner

Udnyttelse eller konvertering af afledt værdipapir modtaget fra virksomheden (såsom en option)

En transaktion rapporteret frivilligt på formular 4

Andet (ledsaget af en fodnote, der beskriver transaktionen)

TSRO / TESARO, Inc. - Insider Trading and Ownership Report - SEC Form 3, 4, 5