| Insideraktier | 47.700.181 shares |
Insider-stemningsscore
Insider Sentiment Score viser, at virksomhederne bliver købt af virksomheders insidere.
Det er resultatet af en sofistikeret, multi-faktor kvantitativ model, der identificerer virksomheder med de højeste niveauer af insider-akkumulering. Scoringsmodellen bruger en kombination af nettoantallet af insidere, der har købt de foregående 90 dage, det samlede antal aktier købt som en procentdel af float og det samlede antal aktier ejet af insidere. Tallet går fra 0 til 100, hvor højere tal indikerer et højere niveau af akkumulering for sine jævnaldrende, og 50 er gennemsnittet.
Opdateringsfrekvens: Dagligt
Se Insiders Top Picks, som giver en liste over virksomheder med den højeste insider-akkumulering.
Officers sentiment score
Officer Sentiment Score finder virksomheder, der bliver købt af Corporate Officers.
Per definition er Corporate Officers Corporate Insiders, men i modsætning til nogle af de andre Insiders (10 % aktionærer og bestyrelsesmedlemmer), arbejder officerer for virksomheden på daglig basis, og de bruger deres egne penge, når de handler . (10 % aktionærer og bestyrelsesmedlemmer er ofte fondsforvaltere, der administrerer andres penge.) Som sådan er insiderhandler foretaget af embedsmænd meget mere betydningsfulde og bør behandles passende.
Ligesom Insider Sentiment Score er Officer Sentiment Score resultatet af en sofistikeret, multi-faktor kvantitativ model, der identificerer virksomheder med de højeste niveauer af officerakkumulering.
Opdateringsfrekvens: Dagligt
Se Insiders Top Picks, som giver en liste over virksomheder med højeste insider-stemning.
Nøgle Insider Metrics
Dette kort viser, hvordan virksomheden rangerer langs forskellige insider-metrics. Percentilrangen viser, hvordan denne virksomhed sammenligner sig med andre virksomheder på de amerikanske markeder. Højere placeringer er tegn på bedre situationer.
For eksempel er det generelt accepteret, at insider-køb er en positiv indikator, så virksomheder med flere insider-køb vil rangere højere end virksomheder med mindre insider-køb (eller endda insider-salg).
Netto antal insidere, der køber (rang)
N/A
Netto antal insidere, der køber, er det samlede antal insiders, der køber minus det samlede antal insiders, der har solgt inden for de sidste 90 dage. Percentilrangen vises her (spænder fra 0 til 100%).
Procent af float købt af insidere (rangering)
N/A
Procent af float købt af insidere er det samlede antal aktier købt af insidere minus det samlede antal aktier solgt af insidere inden for de sidste 90 dage, divideret med den samlede float og ganget med 100.
Insiderhandelsdiagram
Orexigen Therapeutics, Inc. insiderhandler er vist i følgende diagram. Insidere er embedsmænd, direktører eller betydelige investorer i en virksomhed. Generelt er det generelt ulovligt for insidere at foretage handler i deres virksomheder baseret på væsentlige, ikke-offentlige oplysninger. Dette betyder ikke, at det er ulovligt for dem at handle i deres egne virksomheder. De skal dog rapportere alle handler til SEC via en formular 4.
Insiderliste og lønsomhedsmålinger
Denne tabel viser listen over kendte insidere og genereres automatisk fra arkiveringer, der er videregivet til SEC. Ud over navnene, den seneste titel og direktør, officer eller 10 % ejerbetegnelse giver vi de seneste offentliggjorte besiddelser. Derudover giver vi, når det er muligt, den historiske handelspræstation for insideren. Den historiske handelspræstation er et vægtet gennemsnit af præstationen af faktiske købstransaktioner på det åbne marked foretaget af insideren. For mere information om, hvordan dette beregnes, se dette YouTube-webinar.
See our leaderboard of most profitable insider traders.
| Insider | Gennemsnitlig fortjeneste (%) | Aktier Ejet |
Dele Justeret |
|---|
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Track Records af insiderkøb - Kortsigtet profitanalyse
I dette afsnit analyserer vi rentabiliteten af ethvert uplanlagt insiderkøb i åbent marked foretaget i OREX / Orexigen Therapeutics, Inc.. Denne analyse hjælper med at forstå, om insideren konsekvent genererer unormale afkast og er værd at følge. Denne analyse er for et år efter hver handel, og resultaterne er teoretiske .
Følgende tabel viser de seneste køb på det åbne marked, der ikke var en del af en automatisk handelsplan.
Justeret pris er den split-justerede pris. Adjusted Shares er de split-justerede aktier.
Track Records af insidersalg - Kortsigtet tabsanalyse
I dette afsnit analyserer vi den kortsigtede undgåelse af tab af ethvert uplanlagt insidersalg på åbent marked, der foretages i OREX / Orexigen Therapeutics, Inc.. Et konsekvent mønster af tabsforebyggelse kan tyde på, at fremtidige salgstransaktioner kan forudsige prisfald. Denne analyse er for et år efter hver handel, og resultaterne er teoretiske .
Følgende tabel viser de seneste salg på det åbne marked, der ikke var en del af en automatisk handelsplan.
Justeret pris er den split-justerede pris. Adjusted Shares er de split-justerede aktier.
Transaktionshistorik
Klik på linkikonet for at se den fulde transaktionshistorik. Transaktioner, der rapporteres som en del af en automatisk handelsplan 10b5-1, vil have et X i kolonnen markeret 10b-5.
| Fil Dato |
Handle Dato |
Form | Insider | Ticker | Sikkerhedstitel | Kode | Direkte | Dyrke motion Pris |
Enhed Pris |
Enheder Ændret |
Værdi Ændret (1K) |
Tilbage Muligheder |
Tilbage Aktier |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2019-06-04 | 2019-05-31 | 4 | BAUPOST GROUP LLC/MA | OREXQ | 0% Senior Secured Convertible Notes due 2020 | I | 7,50 | 0 | ||||||
| 2019-06-04 | 2019-05-31 | 4 | BAUPOST GROUP LLC/MA | OREXQ | Warrant Expiring 2026 | I | 15,00 | -100.000.000 | 0 | |||||
| 2019-06-04 | 2019-05-31 | 4 | BAUPOST GROUP LLC/MA | OREXQ | Warrant Expiring 2020 | I | 60,00 | -5.000.000 | 0 | |||||
| 2018-10-31 | 2018-10-31 | 4 | BAUPOST GROUP LLC/MA See footnote 1 and 2 | OREXQ | Common Stock | I | 0,0100 | -896.339 | -9 | 0 | ||||
| 2018-10-31 | 2018-10-29 | 4 | BAUPOST GROUP LLC/MA See footnote 1 and 2 | OREXQ | Common Stock | I | 0,0100 | -650.000 | -6 | 896.339 | ||||
| 2018-10-26 | 2018-10-25 | 4 | BAUPOST GROUP LLC/MA See footnote 1 and 2 | OREXQ | Common Stock | I | 0,0100 | -652.500 | -7 | 1.546.339 | ||||
| 2018-10-26 | 2018-10-24 | 4 | BAUPOST GROUP LLC/MA See footnote 1 and 2 | OREXQ | Common Stock | I | 0,0100 | -28.000 | -0 | 2.198.839 | ||||
| 2018-04-26 | 2018-04-13 | 4 | BAUPOST GROUP LLC/MA See footnote 1 and 2 | OREX | 0% Senior Secured Convertible Notes due 2020 | I | 7,50 | -16.483.517 | 7.802.197 | |||||
| 2018-03-16 | 2018-03-15 | 4 | Moglia Stephen A. | OREX | Common Stock | D | 0,2400 | -1.694 | -0 | 0 | ||||
| 2018-03-09 | 3 | Moglia Stephen A. | OREX | Common Stock | D | 3.388 | ||||||||
| 2018-03-09 | 3 | Moglia Stephen A. | OREX | Common Stock | D | 3.388 | ||||||||
| 2017-10-17 | 2017-10-13 | 4 | NARACHI MICHAEL | OREX | Restricted Stock Unit (RSU) | D | 252.000 | 252.000 | ||||||
| 2017-10-17 | 2017-10-13 | 4 | Cannell Thomas R | OREX | Restricted Stock Units (RSU) | D | 91.200 | 91.200 | ||||||
| 2017-10-17 | 2017-10-13 | 4 | Flynn Peter D | OREX | Restricted Stock Unit (RSU) | D | 69.600 | 69.600 | ||||||
| 2017-10-17 | 2017-10-13 | 4 | Keyes Jason A | OREX | Restricted Stock Unit (RSU) | D | 69.600 | 69.600 | ||||||
| 2017-10-17 | 2017-10-13 | 4 | Lynch Thomas P. | OREX | Restricted Stock Unit (RSU) | D | 69.600 | 69.600 | ||||||
| 2017-07-18 | 2017-07-14 | 4 | Zoth Lota S. | OREX | Stock Option (Right to Buy) | D | 2,88 | 5.000 | 5.000 | |||||
| 2017-07-18 | 2017-07-14 | 4 | MAHAFFY PATRICK J | OREX | Stock Option (Right to Buy) | D | 2,88 | 5.000 | 5.000 | |||||
| 2017-07-18 | 2017-07-14 | 4 | JORN DEBORA | OREX | Stock Option (Right to Buy) | D | 2,88 | 5.000 | 5.000 | |||||
| 2017-07-18 | 2017-07-14 | 4 | Honig Peter | OREX | Stock Option (Right to Buy) | D | 2,88 | 5.000 | 5.000 | |||||
| 2017-07-18 | 2017-07-14 | 4 | Endicott David J. | OREX | Stock Option (Right to Buy) | D | 2,88 | 5.000 | 5.000 | |||||
| 2017-07-18 | 2017-07-14 | 4 | BOCK LOUIS C | OREX | Stock Option (Right to Buy) | D | 2,88 | 5.000 | 5.000 | |||||
| 2017-07-18 | 2017-07-14 | 4 | DOVEY BRIAN H | OREX | Stock Option (Right to Buy) | D | 2,88 | 5.000 | 5.000 | |||||
| 2017-06-02 | 2017-05-31 | 4 | NARACHI MICHAEL | OREX | Common Stock | D | 1,5500 | 626 | 1 | 8.356 | ||||
| 2017-06-02 | 2017-05-31 | 4 | Keyes Jason A | OREX | Common Stock | D | 1,5500 | 557 | 1 | 3.031 | ||||
| 2017-06-02 | 2017-05-31 | 4 | Lynch Thomas P. | OREX | Common Stock | D | 1,5500 | 1.704 | 3 | 1.704 | ||||
| 2017-06-02 | 2017-05-31 | 4 | Cannell Thomas R | OREX | Common Stock | D | 1,5500 | 2.119 | 3 | 3.882 | ||||
| 2017-02-07 | 2017-02-03 | 4 | Cannell Thomas R | OREX | Stock Option | D | 15,00 | 72.000 | 144.000 | |||||
| 2017-02-07 | 2017-02-03 | 4 | Cannell Thomas R | OREX | Stock Option | D | 4,10 | 144.000 | 144.000 | |||||
| 2017-02-07 | 2017-02-03 | 4 | Flynn Peter D | OREX | Stock Option | D | 15,00 | 43.500 | 43.500 | |||||
| 2017-02-07 | 2017-02-03 | 4 | Flynn Peter D | OREX | Stock Option | D | 4,10 | 87.000 | 87.000 | |||||
| 2017-02-07 | 2017-02-03 | 4 | Keyes Jason A | OREX | Stock Option | D | 15,00 | 43.500 | 43.500 | |||||
| 2017-02-07 | 2017-02-03 | 4 | Keyes Jason A | OREX | Stock Option | D | 4,10 | 87.000 | 87.000 | |||||
| 2017-02-07 | 2017-02-03 | 4 | Lynch Thomas P. | OREX | Stock Option | D | 15,00 | 43.500 | 43.500 | |||||
| 2017-02-07 | 2017-02-03 | 4 | Lynch Thomas P. | OREX | Stock Option | D | 4,10 | 87.000 | 87.000 | |||||
| 2017-02-07 | 2017-02-03 | 4 | NARACHI MICHAEL | OREX | Stock Option | D | 15,00 | 157.500 | 157.500 | |||||
| 2017-02-07 | 2017-02-03 | 4 | NARACHI MICHAEL | OREX | Stock Option | D | 4,10 | 315.000 | 315.000 | |||||
| 2016-12-21 | 2016-12-19 | 4 | Moglia Stephen A. | OREX | Common Stock | D | 1,9600 | -800 | -2 | 0 | ||||
| 2016-12-02 | 2016-11-30 | 4 | NARACHI MICHAEL | OREX | Common Stock | D | 1,6700 | 802 | 1 | 6.312 | ||||
| 2016-12-02 | 2016-11-30 | 4 | Cannell Thomas R | OREX | Common Stock | D | 1,6700 | 291 | 0 | 1.763 | ||||
| 2016-12-02 | 2016-11-30 | 4 | Keyes Jason A | OREX | Common Stock | D | 1,6700 | 291 | 0 | 2.474 | ||||
| 2016-07-14 | 3 | Flynn Peter D | OREX | Common Stock | D | 2.472 | ||||||||
| 2016-07-14 | 3 | Flynn Peter D | OREX | Common Stock | D | 2.472 | ||||||||
| 2016-07-14 | 2016-07-12 | 4 | DOVEY BRIAN H | OREX | Stock Option (Right to Buy) | D | 4,02 | 15.000 | 15.000 | |||||
| 2016-07-14 | 2016-07-12 | 4 | BOCK LOUIS C | OREX | Stock Option | D | 4,02 | 15.000 | 15.000 | |||||
| 2016-07-14 | 2016-07-12 | 4 | MAHAFFY PATRICK J | OREX | Stock Option | D | 4,02 | 15.000 | 15.000 | |||||
| 2016-07-14 | 2016-07-12 | 4 | Zoth Lota S. | OREX | Stock Option | D | 4,02 | 15.000 | 15.000 | |||||
| 2016-07-14 | 2016-07-12 | 4 | NARACHI MICHAEL | OREX | Stock Option | D | 15,00 | 63.000 | 63.000 | |||||
| 2016-07-14 | 2016-07-12 | 4 | NARACHI MICHAEL | OREX | Stock Option | D | 15,00 | 315.000 | 315.000 | |||||
| 2016-07-14 | 2016-07-12 | 4 | NARACHI MICHAEL | OREX | Stock Option | D | 4,02 | 105.000 | 105.000 | |||||
| 2016-07-14 | 2016-07-12 | 4 | NARACHI MICHAEL | OREX | Stock Option | D | 4,02 | 525.000 | 525.000 | |||||
| 2016-07-14 | 2016-07-12 | 4 | Honig Peter | OREX | Stock Option | D | 4,02 | 15.000 | 15.000 | |||||
| 2016-07-14 | 2016-07-12 | 4 | Endicott David J. | OREX | Stock Option | D | 4,02 | 15.000 | 15.000 | |||||
| 2016-07-14 | 2016-07-12 | 4 | Flynn Peter D | OREX | Stock Option | D | 15,00 | 15.750 | 15.750 | |||||
| 2016-07-14 | 2016-07-12 | 4 | Flynn Peter D | OREX | Stock Option | D | 15,00 | 78.750 | 78.750 | |||||
| 2016-07-14 | 2016-07-12 | 4 | Flynn Peter D | OREX | Stock Option | D | 4,02 | 26.250 | 26.250 | |||||
| 2016-07-14 | 2016-07-12 | 4 | Flynn Peter D | OREX | Stock Option | D | 4,02 | 131.250 | 131.250 | |||||
| 2016-07-14 | 2016-07-12 | 4 | Cannell Thomas R | OREX | Stock Option | D | 15,00 | 31.500 | 31.500 | |||||
| 2016-07-14 | 2016-07-12 | 4 | Cannell Thomas R | OREX | Stock Option | D | 15,00 | 157.500 | 157.500 | |||||
| 2016-07-14 | 2016-07-12 | 4 | Cannell Thomas R | OREX | Stock Option | D | 4,02 | 52.500 | 52.500 | |||||
| 2016-07-14 | 2016-07-12 | 4 | Cannell Thomas R | OREX | Stock Option | D | 4,02 | 262.500 | 262.500 | |||||
| 2016-07-14 | 2016-07-12 | 4 | JORN DEBORA | OREX | Stock Option | D | 4,02 | 16.500 | 16.500 | |||||
| 2016-07-14 | 2016-07-12 | 4 | Lynch Thomas P. | OREX | Stock Option | D | 15,00 | 15.750 | 15.750 | |||||
| 2016-07-14 | 2016-07-12 | 4 | Lynch Thomas P. | OREX | Stock Option | D | 15,00 | 78.750 | 78.750 | |||||
| 2016-07-14 | 2016-07-12 | 4 | Lynch Thomas P. | OREX | Stock Option | D | 4,02 | 26.250 | 26.250 | |||||
| 2016-07-14 | 2016-07-12 | 4 | Lynch Thomas P. | OREX | Stock Option | D | 4,02 | 131.250 | 131.250 | |||||
| 2016-07-14 | 2016-07-12 | 4 | Moglia Stephen A. | OREX | Stock Option | D | 15,00 | 28.800 | 28.800 | |||||
| 2016-07-14 | 2016-07-12 | 4 | Moglia Stephen A. | OREX | Stock Option | D | 4,02 | 48.000 | 48.000 | |||||
| 2016-07-14 | 2016-07-12 | 4 | Keyes Jason A | OREX | Stock Option | D | 15,00 | 15.750 | 15.750 | |||||
| 2016-07-14 | 2016-07-12 | 4 | Keyes Jason A | OREX | Stock Option | D | 15,00 | 78.750 | 78.750 | |||||
| 2016-07-14 | 2016-07-12 | 4 | Keyes Jason A | OREX | Stock Option | D | 4,02 | 26.250 | 26.250 | |||||
| 2016-07-14 | 2016-07-12 | 4 | Keyes Jason A | OREX | Stock Option | D | 4,02 | 131.250 | 131.250 | |||||
| 2016-07-01 | 3 | Keyes Jason A | OREX | Common Stock | D | 43.664 | ||||||||
| 2016-07-01 | 3 | Keyes Jason A | OREX | Common Stock | D | 43.664 | ||||||||
| 2016-06-02 | 2016-05-31 | 4 | NARACHI MICHAEL | OREX | Common Stock | D | 0,3400 | 8.777 | 3 | 69.285 | ||||
| 2016-06-02 | 2016-05-31 | 4 | Cannell Thomas R | OREX | Common Stock | D | 0,3400 | 9.632 | 3 | 14.723 | ||||
| 2016-05-24 | 2016-05-20 | 4 | JORN DEBORA | OREX | Stock Option | D | 0,40 | 70.000 | 70.000 | |||||
| 2016-03-24 | 3 | KLARMAN SETH A See footnote 1. | OREX | Common Stock | I | 44.536.798 | ||||||||
| 2016-03-24 | 3 | KLARMAN SETH A See footnote 1. | OREX | Common Stock | I | 44.536.798 | ||||||||
| 2016-03-24 | 3 | KLARMAN SETH A See footnote 1. | OREX | Common Stock | I | 44.536.798 | ||||||||
| 2016-03-24 | 3 | KLARMAN SETH A See footnote 1. | OREX | Common Stock | I | 44.536.798 | ||||||||
| 2016-02-04 | 3 | Moglia Stephen A. | OREX | Common Stock | D | 16.000 | ||||||||
| 2016-02-04 | 3 | Moglia Stephen A. | OREX | Common Stock | D | 16.000 | ||||||||
| 2016-02-04 | 3 | ACE HEATHER S | OREX | No Securities are beneficially owned | D | 0 | ||||||||
| 2016-02-04 | 2016-02-02 | 4 | Moglia Stephen A. | OREX | Performance Stock Units | D | 90.000 | 90.000 | ||||||
| 2016-02-04 | 2016-02-02 | 4 | Moglia Stephen A. | OREX | Stock Option (right to buy) | D | 1,78 | 65.000 | 65.000 | |||||
| 2016-02-04 | 2016-02-02 | 4 | ACE HEATHER S | OREX | Performance Stock Units | D | 225.000 | 225.000 | ||||||
| 2016-02-04 | 2016-02-02 | 4 | Lynch Thomas P. | OREX | Performance Stock Units | D | 255.000 | 255.000 | ||||||
| 2016-02-04 | 2016-02-02 | 4 | Klassen Preston | OREX | Performance Stock Units | D | 350.000 | 350.000 | ||||||
| 2016-02-04 | 2016-02-02 | 4 | Klassen Preston | OREX | Stock Option (right to buy) | D | 1,78 | 190.000 | 190.000 | |||||
| 2016-02-04 | 2015-11-30 | 4 | Klassen Preston | OREX | Common Stock | D | 2,0300 | 4.170 | 8 | 10.160 | ||||
| 2016-02-04 | 2015-05-30 | 4 | Klassen Preston | OREX | Common Stock | D | 4,1700 | 1.860 | 8 | 5.990 | ||||
| 2016-02-04 | 2016-02-02 | 4 | Cannell Thomas R | OREX | Performance Stock Units | D | 350.000 | 350.000 | ||||||
| 2016-02-04 | 2016-02-02 | 4 | Cannell Thomas R | OREX | Stock Option (right to buy) | D | 1,78 | 390.000 | 390.000 | |||||
| 2016-02-04 | 2015-11-30 | 4 | Cannell Thomas R | OREX | Common Stock | D | 2,0300 | 5.091 | 10 | 5.091 | ||||
| 2016-02-04 | 2016-01-11 | 4 | ACE HEATHER S | OREX | Stock Option (right to buy) | D | 1,57 | 325.000 | 325.000 | |||||
| 2016-02-04 | 2016-02-02 | 4 | NARACHI MICHAEL | OREX | Performance Stock Units | D | 800.000 | 800.000 | ||||||
| 2016-02-04 | 2016-02-02 | 4 | NARACHI MICHAEL | OREX | Stock Option (right to buy) | D | 1,78 | 700.000 | 700.000 | |||||
| 2016-02-04 | 2015-11-30 | 4 | NARACHI MICHAEL | OREX | Common Stock | D | 2,0300 | 1.761 | 4 | 60.508 | ||||
| 2016-02-04 | 2015-05-29 | 4 | NARACHI MICHAEL | OREX | Common Stock | D | 4,1700 | 721 | 3 | 58.747 | ||||
| 2015-12-02 | 2015-12-01 | 4 | Lynch Thomas P. | OREX | Stock Option (right to buy) | D | 2,29 | 350.000 | 350.000 | |||||
| 2015-06-10 | 2015-06-09 | 4 | DOVEY BRIAN H | OREX | Stock Option (Right to Buy) | D | 4,63 | 50.000 | 50.000 | |||||
| 2015-06-10 | 2015-06-09 | 4 | WEBER ECKARD | OREX | Stock Option (right to buy) | D | 4,63 | 50.000 | 50.000 | |||||
| 2015-06-10 | 2015-06-09 | 4 | BOCK LOUIS C | OREX | Stock Option (right to buy) | D | 4,63 | 50.000 | 50.000 | |||||
| 2015-06-10 | 2015-06-09 | 4 | DIXON WENDY L | OREX | Stock Option (right to buy) | D | 4,63 | 50.000 | 50.000 | |||||
| 2015-06-10 | 2015-06-09 | 4 | MAHAFFY PATRICK J | OREX | Stock Option (right to buy) | D | 4,63 | 50.000 | 50.000 | |||||
| 2015-06-10 | 2015-06-09 | 4 | Zoth Lota S. | OREX | Stock Option (right to buy) | D | 4,63 | 50.000 | 50.000 | |||||
| 2015-06-10 | 2015-06-09 | 4 | Honig Peter | OREX | Stock Option (right to buy) | D | 4,63 | 50.000 | 50.000 | |||||
| 2015-06-10 | 2015-06-09 | 4 | Endicott David J. | OREX | Stock Option (right to buy) | D | 4,63 | 50.000 | 50.000 | |||||
| 2015-03-31 | 2015-03-30 | 4 | Cannell Thomas R | OREX | Stock Option (right to buy) | D | 7,75 | 425.000 | 425.000 | |||||
| 2015-03-02 | 2015-02-26 | 4 | Booth Mark D | OREX | Stock Option (right to buy) | D | 1,66 | -50.000 | 563.924 | |||||
| 2015-03-02 | 2015-02-26 | 4 | Booth Mark D | OREX | Common Stock | D | 5,6840 | -50.000 | -284 | 3.810 | ||||
| 2015-03-02 | 2015-02-26 | 4 | Booth Mark D | OREX | Common Stock | D | 1,6600 | 50.000 | 83 | 53.810 | ||||
| 2015-02-05 | 2015-02-03 | 4 | NARACHI MICHAEL | OREX | Stock Option (right to buy) | D | 5,34 | 635.150 | 635.150 | |||||
| 2015-02-05 | 2015-02-03 | 4 | Turner Heather D | OREX | Stock Option (right to buy) | D | 5,34 | 153.050 | 153.050 | |||||
| 2015-02-05 | 2015-02-03 | 4 | Booth Mark D | OREX | Stock Option (right to buy) | D | 5,34 | 88.925 | 88.925 | |||||
| 2015-02-05 | 2014-05-30 | 4 | Booth Mark D | OREX | Common Stock | D | 5,2500 | 4.218 | 22 | 8.028 | ||||
| 2015-02-05 | 2015-02-03 | 4 | Klassen Preston | OREX | Stock Option (right to buy) | D | 5,34 | 182.650 | 182.650 | |||||
| 2015-02-05 | 2014-11-28 | 4 | Klassen Preston | OREX | Common Stock | D | 4,9200 | 1.542 | 8 | 4.130 | ||||
| 2015-02-05 | 2014-05-30 | 4 | Klassen Preston | OREX | Common Stock | D | 5,2500 | 1.318 | 7 | 2.588 | ||||
| 2015-02-05 | 2015-02-03 | 4 | Hagan Joseph P | OREX | Stock Option (right to buy) | D | 5,34 | 202.650 | 202.650 | |||||
| 2014-12-04 | 2014-12-02 | 4 | Turner Heather D | OREX | Stock Option (right to buy) | D | 1,66 | -22.643 | 656.932 | |||||
| 2014-12-04 | 2014-12-02 | 4 | Turner Heather D | OREX | Common Stock | D | 6,0000 | -22.643 | -136 | 0 | ||||
| 2014-12-04 | 2014-12-02 | 4 | Turner Heather D | OREX | Common Stock | D | 1,6600 | 22.643 | 38 | 22.643 | ||||
| 2014-11-26 | 2014-11-25 | 4 | Turner Heather D | OREX | Stock Option (right to buy) | D | 1,66 | -7.382 | 679.575 | |||||
| 2014-11-26 | 2014-11-25 | 4 | Turner Heather D | OREX | Common Stock | D | 6,0000 | -7.382 | -44 | 0 | ||||
| 2014-11-26 | 2014-11-25 | 4 | Turner Heather D | OREX | Common Stock | D | 1,6600 | 7.382 | 12 | 7.382 | ||||
| 2014-11-26 | 2014-11-24 | 4 | Turner Heather D | OREX | Stock Option (right to buy) | D | 1,66 | -24.006 | 686.957 | |||||
| 2014-11-26 | 2014-11-24 | 4 | Turner Heather D | OREX | Common Stock | D | 5,7730 | -24.006 | -139 | 0 | ||||
| 2014-11-26 | 2014-11-24 | 4 | Turner Heather D | OREX | Common Stock | D | 1,6600 | 24.006 | 40 | 24.006 | ||||
| 2014-11-20 | 2014-11-18 | 4 | BOCK LOUIS C By Spouse | OREX | Common Stock | I | 5,5790 | 700 | 4 | 700 | ||||
| 2014-11-20 | 2014-11-18 | 4 | BOCK LOUIS C | OREX | Common Stock | D | 5,5790 | 625 | 3 | 27.677 | ||||
| 2014-11-13 | 2014-11-12 | 4 | BOCK LOUIS C | OREX | Common Stock | D | 5,5650 | 27.052 | 151 | 27.052 | ||||
| 2014-09-22 | 2014-09-22 | 4 | Turner Heather D | OREX | Stock Option (right to buy) | D | 1,66 | -300.000 | 710.963 | |||||
| 2014-09-22 | 2014-09-22 | 4 | Turner Heather D | OREX | Common Stock | D | 4,4650 | -300.000 | -1.340 | 0 | ||||
| 2014-09-22 | 2014-09-22 | 4 | Turner Heather D | OREX | Common Stock | D | 1,6600 | 300.000 | 498 | 300.000 | ||||
| 2014-09-15 | 2014-09-15 | 4 | NARACHI MICHAEL | OREX | Common Stock | D | 4,7820 | 50.000 | 239 | 58.026 | ||||
| 2014-09-15 | 2014-09-15 | 4 | Hagan Joseph P | OREX | Common Stock | D | 4,6900 | 5.000 | 23 | 13.026 | ||||
| 2014-06-30 | 2014-06-27 | 4 | DOVEY BRIAN H | OREX | Stock Option (Right to Buy) | D | 5,97 | 50.000 | 50.000 | |||||
| 2014-06-27 | 2014-06-27 | 4 | WEBER ECKARD | OREX | Stock Option (right to buy) | D | 5,97 | 50.000 | 50.000 | |||||
| 2014-06-27 | 2014-06-27 | 4 | DIXON WENDY L | OREX | Stock Option (right to buy) | D | 5,97 | 50.000 | 50.000 | |||||
| 2014-06-27 | 2014-06-27 | 4 | BOCK LOUIS C | OREX | Stock Option (right to buy) | D | 5,97 | 50.000 | 50.000 | |||||
| 2014-06-27 | 2014-06-27 | 4 | Zoth Lota S. | OREX | Stock Option (right to buy) | D | 5,97 | 50.000 | 50.000 | |||||
| 2014-06-27 | 2014-06-27 | 4 | MAHAFFY PATRICK J | OREX | Stock Option (right to buy) | D | 5,97 | 50.000 | 50.000 | |||||
| 2014-06-27 | 2014-06-27 | 4 | Honig Peter | OREX | Stock Option (right to buy) | D | 5,97 | 50.000 | 50.000 | |||||
| 2014-06-27 | 2014-06-27 | 4 | Endicott David J. | OREX | Stock Option (right to buy) | D | 5,97 | 50.000 | 50.000 | |||||
| 2014-04-23 | 2014-04-22 | 4 | DOVEY BRIAN H By DP VII Associates, L.P. | OREX | Warrant to Purchase Common Stock | I | 0,00 | -7.882 | 0 | |||||
| 2014-04-23 | 2014-04-22 | 4 | DOVEY BRIAN H By Domain Partners VII, L.P. | OREX | Warrant to Purchase Common Stock | I | 0,00 | -461.265 | 0 | |||||
| 2014-04-23 | 2014-04-22 | 4 | DOVEY BRIAN H By DP VII Associates, L.P. | OREX | Common Stock | I | 5,3000 | -15 | -0 | 129.448 | ||||
| 2014-04-23 | 2014-04-22 | 4 | DOVEY BRIAN H By DP VII Associates, L.P. | OREX | Common Stock | I | 0,0010 | 78.820 | 0 | 129.463 | ||||
| 2014-04-23 | 2014-04-22 | 4 | DOVEY BRIAN H By Domain Partners VII, L.P. | OREX | Common Stock | I | 5,3000 | -871 | -5 | 7.579.194 | ||||
| 2014-04-23 | 2014-04-22 | 4 | DOVEY BRIAN H By Domain Partners VII, L.P. | OREX | Common Stock | I | 0,0010 | 4.612.650 | 5 | 7.580.065 | ||||
| 2014-02-11 | 2014-02-07 | 4 | NARACHI MICHAEL | OREX | Stock Option (right to buy) | D | 6,30 | 673.500 | 673.500 | |||||
| 2014-02-11 | 2013-11-29 | 4 | NARACHI MICHAEL | OREX | Common Stock | D | 5,3400 | 3.980 | 21 | 3.980 | ||||
| 2014-02-11 | 2014-02-07 | 4 | Turner Heather D | OREX | Stock Option (right to buy) | D | 6,30 | 205.000 | 205.000 | |||||
| 2014-02-11 | 2013-11-29 | 4 | Turner Heather D | OREX | Common Stock | D | 5,3400 | 3.980 | 21 | 3.980 | ||||
| 2014-02-11 | 2014-02-07 | 4 | Hagan Joseph P | OREX | Stock Option (right to buy) | D | 6,30 | 225.000 | 225.000 | |||||
| 2014-02-11 | 2013-11-29 | 4 | Hagan Joseph P | OREX | Common Stock | D | 5,3400 | 3.980 | 21 | 3.980 | ||||
| 2014-02-11 | 2014-02-07 | 4 | Booth Mark D | OREX | Stock Option (right to buy) | D | 6,30 | 205.000 | 205.000 | |||||
| 2014-02-11 | 2013-11-29 | 4 | Booth Mark D | OREX | Common Stock | D | 5,3400 | 3.810 | 20 | 3.810 | ||||
| 2014-02-11 | 2014-02-07 | 4 | Klassen Preston | OREX | Stock Option (right to buy) | D | 6,30 | 205.000 | 205.000 | |||||
| 2014-02-11 | 2013-11-29 | 4 | Klassen Preston | OREX | Common Stock | D | 5,3400 | 1.270 | 7 | 1.270 | ||||
| 2013-08-28 | 2013-06-05 | 4/A | Endicott David J. | OREX | Stock Option (right to buy) | D | 6,09 | 18.126 | 18.126 | |||||
| 2013-08-02 | 2013-07-31 | 4 | Hagan Joseph P | OREX | Stock Option (right to buy) | D | 1,66 | -12.000 | 764.000 | |||||
| 2013-08-02 | 2013-07-31 | 4 | Hagan Joseph P | OREX | Common Stock | D | 7,8000 | -12.000 | -94 | 0 | ||||
| 2013-08-02 | 2013-07-31 | 4 | Hagan Joseph P | OREX | Common Stock | D | 1,6600 | 12.000 | 20 | 12.000 | ||||
| 2013-07-29 | 2013-07-26 | 4 | Hagan Joseph P | OREX | Stock Option (right to buy) | D | 1,66 | -10.000 | 776.000 | |||||
| 2013-07-29 | 2013-07-26 | 4 | Hagan Joseph P | OREX | Common Stock | D | 7,4000 | -10.000 | -74 | 0 | ||||
| 2013-07-29 | 2013-07-26 | 4 | Hagan Joseph P | OREX | Common Stock | D | 1,6600 | 10.000 | 17 | 10.000 | ||||
| 2013-07-29 | 2013-07-26 | 4 | Booth Mark D | OREX | Stock Option (right to buy) | D | 1,66 | -64.767 | 613.924 | |||||
| 2013-07-29 | 2013-07-26 | 4 | Booth Mark D | OREX | Common Stock | D | 7,7500 | -29.045 | -225 | 0 | ||||
| 2013-07-29 | 2013-07-26 | 4 | Booth Mark D | OREX | Common Stock | D | 7,5000 | -20.000 | -150 | 29.045 | ||||
| 2013-07-29 | 2013-07-26 | 4 | Booth Mark D | OREX | Common Stock | D | 7,2500 | -15.722 | -114 | 49.045 | ||||
| 2013-07-29 | 2013-07-26 | 4 | Booth Mark D | OREX | Common Stock | D | 1,6600 | 64.767 | 108 | 64.767 | ||||
| 2013-07-29 | 2013-07-25 | 4 | Klassen Preston | OREX | Stock Option (right to buy) | D | 1,66 | -71.229 | 732.000 | |||||
| 2013-07-29 | 2013-07-25 | 4 | Klassen Preston | OREX | Common Stock | D | 7,1600 | -71.229 | -510 | 0 | ||||
| 2013-07-29 | 2013-07-25 | 4 | Klassen Preston | OREX | Common Stock | D | 1,6600 | 71.229 | 118 | 71.229 | ||||
| 2013-06-07 | 2013-06-05 | 4 | DIXON WENDY L | OREX | Stock Option (right to buy) | D | 6,09 | 35.000 | 35.000 | |||||
| 2013-06-07 | 2013-06-05 | 4 | WEBER ECKARD | OREX | Stock Option (right to buy) | D | 6,09 | 35.000 | 35.000 | |||||
| 2013-06-07 | 2013-06-05 | 4 | MAHAFFY PATRICK J | OREX | Stock Option (right to buy) | D | 6,09 | 35.000 | 35.000 | |||||
| 2013-06-07 | 2013-06-05 | 4 | Zoth Lota S. | OREX | Stock Option (right to buy) | D | 6,09 | 35.000 | 35.000 | |||||
| 2013-06-07 | 2013-06-05 | 4 | Honig Peter | OREX | Stock Option (right to buy) | D | 6,09 | 35.000 | 35.000 | |||||
| 2013-06-07 | 2013-06-05 | 4 | Endicott David J. | OREX | Stock Option (right to buy) | D | 6,09 | 35.000 | 35.000 | |||||
| 2013-06-06 | 2013-06-05 | 4 | DOVEY BRIAN H | OREX | Stock Option (Right to Buy) | D | 6,09 | 35.000 | 35.000 | |||||
| 2013-06-06 | 2013-06-05 | 4 | BOCK LOUIS C | OREX | Stock Option (Right to Buy) | D | 6,09 | 35.000 | 35.000 | |||||
| 2013-05-30 | 2013-05-28 | 4 | Hagan Joseph P | OREX | Stock Option (right to buy) | D | 1,66 | -28.000 | 786.000 | |||||
| 2013-05-30 | 2013-05-28 | 4 | Hagan Joseph P | OREX | Common Stock | D | 7,0000 | -28.000 | -196 | 0 | ||||
| 2013-05-30 | 2013-05-28 | 4 | Hagan Joseph P | OREX | Common Stock | D | 1,6600 | 28.000 | 46 | 28.000 | ||||
| 2013-05-30 | 2013-05-28 | 4 | Klassen Preston | OREX | Stock Option (right to buy) | D | 1,66 | -28.771 | 803.229 | |||||
| 2013-05-30 | 2013-05-28 | 4 | Klassen Preston | OREX | Common Stock | D | 7,2072 | -28.771 | -207 | 0 | ||||
| 2013-05-30 | 2013-05-28 | 4 | Klassen Preston | OREX | Common Stock | D | 1,6600 | 28.771 | 48 | 28.771 | ||||
| 2013-03-12 | 2013-03-11 | 4 | Booth Mark D | OREX | Stock Option (right to buy) | D | 1,66 | -27.685 | 678.691 | |||||
| 2013-03-12 | 2013-03-11 | 4 | Booth Mark D | OREX | Common Stock | D | 6,6700 | -27.685 | -185 | 0 | ||||
| 2013-03-12 | 2013-03-11 | 4 | Booth Mark D | OREX | Common Stock | D | 1,6600 | 27.685 | 46 | 27.685 | ||||
| 2013-02-19 | 2013-02-15 | 4 | NARACHI MICHAEL | OREX | Stock Option (right to buy) | D | 5,69 | 555.000 | 555.000 | |||||
| 2013-02-19 | 2013-02-15 | 4 | Turner Heather D | OREX | Stock Option (right to buy) | D | 5,69 | 240.000 | 240.000 | |||||
| 2013-02-19 | 2013-02-15 | 4 | Hagan Joseph P | OREX | Stock Option (right to buy) | D | 5,69 | 310.000 | 310.000 | |||||
| 2013-02-19 | 2013-02-15 | 4 | Booth Mark D | OREX | Stock Option (right to buy) | D | 5,69 | 190.000 | 190.000 | |||||
| 2013-02-19 | 2013-02-15 | 4 | Klassen Preston | OREX | Stock Option (right to buy) | D | 5,69 | 245.000 | 245.000 | |||||
| 2013-01-18 | 2013-01-15 | 4 | Booth Mark D | OREX | Stock Option (right to buy) | D | 1,66 | -22.315 | 706.376 | |||||
| 2013-01-18 | 2013-01-15 | 4 | Booth Mark D | OREX | Common Stock | D | 6,6750 | -100 | -1 | 0 | ||||
| 2013-01-18 | 2013-01-15 | 4 | Booth Mark D | OREX | Common Stock | D | 6,6700 | -22.215 | -148 | 100 | ||||
| 2013-01-18 | 2013-01-15 | 4 | Booth Mark D | OREX | Common Stock | D | 1,6600 | 22.315 | 37 | 22.315 | ||||
| 2012-11-30 | 3 | Endicott David J. | OREX | No securities are beneficially owned | D | 0 | ||||||||
| 2012-11-30 | 2012-11-29 | 4 | Endicott David J. | OREX | Stock Option (right to buy) | D | 4,75 | -35.000 | 35.000 | |||||
| 2012-07-19 | 2012-07-17 | 4 | NARACHI MICHAEL | OREX | Stock Option (right to buy) | D | 1,70 | -25.762 | 1.774.238 | |||||
| 2012-07-19 | 2012-07-17 | 4 | NARACHI MICHAEL | OREX | Stock Option (right to buy) | D | 1,66 | -124.238 | 1.761.562 | |||||
| 2012-07-19 | 2012-07-17 | 4 | NARACHI MICHAEL | OREX | Common Stock | D | 7,6600 | -25.762 | -197 | 0 | ||||
| 2012-07-19 | 2012-07-17 | 4 | NARACHI MICHAEL | OREX | Common Stock | D | 1,7000 | 25.762 | 44 | 25.762 | ||||
| 2012-07-19 | 2012-07-17 | 4 | NARACHI MICHAEL | OREX | Common Stock | D | 7,6600 | -124.238 | -952 | 0 | ||||
| 2012-07-19 | 2012-07-17 | 4 | NARACHI MICHAEL | OREX | Common Stock | D | 1,6600 | 124.238 | 206 | 124.238 | ||||
| 2012-07-19 | 2012-07-17 | 4 | Turner Heather D | OREX | Stock Option (right to buy) | D | 1,66 | -82.433 | 1.010.963 | |||||
| 2012-07-19 | 2012-07-17 | 4 | Turner Heather D | OREX | Common Stock | D | 7,6844 | -82.433 | -633 | 0 | ||||
| 2012-07-19 | 2012-07-17 | 4 | Turner Heather D | OREX | Common Stock | D | 1,6600 | 82.433 | 137 | 82.433 | ||||
| 2012-07-13 | 2012-07-13 | 4 | NARACHI MICHAEL | OREX | Stock Option (right to buy) | D | 1,66 | -147.100 | 1.885.800 | |||||
| 2012-07-13 | 2012-07-13 | 4 | NARACHI MICHAEL | OREX | Common Stock | D | 6,7000 | -147.100 | -986 | 0 | ||||
| 2012-07-13 | 2012-07-13 | 4 | NARACHI MICHAEL | OREX | Common Stock | D | 1,6600 | 147.100 | 244 | 147.100 | ||||
| 2012-07-13 | 2012-07-12 | 4 | NARACHI MICHAEL | OREX | Stock Option (right to buy) | D | 1,66 | -2.900 | 2.032.900 | |||||
| 2012-07-13 | 2012-07-12 | 4 | NARACHI MICHAEL | OREX | Common Stock | D | 6,6600 | -2.900 | -19 | 0 | ||||
| 2012-07-13 | 2012-07-12 | 4 | NARACHI MICHAEL | OREX | Common Stock | D | 1,6600 | 2.900 | 5 | 2.900 | ||||
| 2012-07-13 | 2012-07-13 | 4 | Hagan Joseph P | OREX | Stock Option (right to buy) | D | 1,66 | -30.000 | 814.000 | |||||
| 2012-07-13 | 2012-07-13 | 4 | Hagan Joseph P | OREX | Common Stock | D | 6,9000 | -10.000 | -69 | 0 | ||||
| 2012-07-13 | 2012-07-13 | 4 | Hagan Joseph P | OREX | Common Stock | D | 6,7000 | -20.000 | -134 | 10.000 | ||||
| 2012-07-13 | 2012-07-13 | 4 | Hagan Joseph P | OREX | Common Stock | D | 1,6600 | 30.000 | 50 | 30.000 | ||||
| 2012-06-29 | 2012-06-29 | 4 | NARACHI MICHAEL | OREX | Stock Option (right to buy) | D | 1,66 | -125.000 | 2.035.800 | |||||
| 2012-06-29 | 2012-06-29 | 4 | NARACHI MICHAEL | OREX | Common Stock | D | 6,0800 | -125.000 | -760 | 0 | ||||
| 2012-06-29 | 2012-06-29 | 4 | NARACHI MICHAEL | OREX | Common Stock | D | 1,6600 | 125.000 | 208 | 125.000 | ||||
| 2012-06-29 | 2012-06-28 | 4 | NARACHI MICHAEL | OREX | Stock Option (right to buy) | D | 1,66 | -100.000 | 2.160.800 | |||||
| 2012-06-29 | 2012-06-28 | 4 | NARACHI MICHAEL | OREX | Common Stock | D | 5,6600 | -100.000 | -566 | 0 | ||||
| 2012-06-29 | 2012-06-28 | 4 | NARACHI MICHAEL | OREX | Common Stock | D | 1,6600 | 100.000 | 166 | 100.000 | ||||
| 2012-06-29 | 2012-06-29 | 4 | Hagan Joseph P | OREX | Stock Option (right to buy) | D | 1,66 | -12.000 | 844.000 | |||||
| 2012-06-29 | 2012-06-29 | 4 | Hagan Joseph P | OREX | Common Stock | D | 6,3000 | -12.000 | -76 | 0 | ||||
| 2012-06-29 | 2012-06-29 | 4 | Hagan Joseph P | OREX | Common Stock | D | 1,6600 | 12.000 | 20 | 12.000 | ||||
| 2012-06-29 | 2012-06-28 | 4 | Hagan Joseph P | OREX | Stock Option (right to buy) | D | 1,66 | -26.000 | 856.000 | |||||
| 2012-06-29 | 2012-06-28 | 4 | Hagan Joseph P | OREX | Common Stock | D | 5,9000 | -26.000 | -153 | 0 | ||||
| 2012-06-29 | 2012-06-28 | 4 | Hagan Joseph P | OREX | Common Stock | D | 1,6600 | 26.000 | 43 | 26.000 | ||||
| 2012-06-29 | 2012-06-27 | 4 | Hagan Joseph P | OREX | Stock Option (right to buy) | D | 1,66 | -70.000 | 882.000 | |||||
| 2012-06-29 | 2012-06-27 | 4 | Hagan Joseph P | OREX | Common Stock | D | 5,5000 | -30.000 | -165 | 0 | ||||
| 2012-06-29 | 2012-06-27 | 4 | Hagan Joseph P | OREX | Common Stock | D | 5,2500 | -20.000 | -105 | 30.000 | ||||
| 2012-06-29 | 2012-06-27 | 4 | Hagan Joseph P | OREX | Common Stock | D | 4,9000 | -20.000 | -98 | 50.000 | ||||
| 2012-06-29 | 2012-06-27 | 4 | Hagan Joseph P | OREX | Common Stock | D | 1,6600 | 70.000 | 116 | 70.000 | ||||
| 2012-06-29 | 2012-06-28 | 4 | Booth Mark D | OREX | Stock Option (right to buy) | D | 1,66 | -103.309 | 728.691 | |||||
| 2012-06-29 | 2012-06-28 | 4 | Booth Mark D | OREX | Common Stock | D | 5,6600 | -103.309 | -585 | 0 | ||||
| 2012-06-29 | 2012-06-28 | 4 | Booth Mark D | OREX | Common Stock | D | 1,6600 | 103.309 | 171 | 103.309 | ||||
| 2012-06-12 | 2012-06-07 | 4 | DOVEY BRIAN H | OREX | Stock Option (Right to Buy) | D | 3,12 | 35.000 | 35.000 | |||||
| 2012-06-11 | 2012-06-07 | 4 | DIXON WENDY L | OREX | Stock Option (right to buy) | D | 3,12 | 35.000 | 35.000 | |||||
| 2012-06-11 | 2012-06-07 | 4 | MAHAFFY PATRICK J | OREX | Stock Option (right to buy) | D | 3,12 | 35.000 | 35.000 | |||||
| 2012-06-11 | 2012-06-07 | 4 | BOCK LOUIS C | OREX | Stock Option (right to buy) | D | 3,12 | 35.000 | 35.000 | |||||
| 2012-06-11 | 2012-06-07 | 4 | Zoth Lota S. | OREX | Stock Option (right to buy) | D | 3,12 | -35.000 | 35.000 | |||||
| 2012-06-11 | 2012-06-07 | 4 | WEBER ECKARD | OREX | Stock Option (right to buy) | D | 3,12 | 35.000 | 35.000 | |||||
| 2012-06-11 | 2012-06-07 | 4 | Honig Peter | OREX | Stock Option (right to buy) | D | 3,12 | 35.000 | 35.000 | |||||
| 2012-04-30 | 2012-04-26 | 4 | Zoth Lota S. | OREX | Stock Option (right to buy) | D | 3,68 | -35.000 | 35.000 | |||||
| 2012-04-30 | 3 | Zoth Lota S. | OREX | No securities are beneficially owned | D | 0 | ||||||||
| 2012-02-28 | 2012-02-27 | 4 | Booth Mark D | OREX | Stock Option (right to buy) | D | 4,16 | 70.000 | 70.000 | |||||
| 2012-02-06 | 2011-12-22 | 4 | TURNER DANIEL K III | OREX | Warrant to Purchase Common Stock | I | 0,00 | 14,4900 | 28.602 | 414 | 28.602 | |||
| 2012-02-06 | 2011-12-22 | 4 | TURNER DANIEL K III | OREX | Warrant to Purchase Common Stock | I | 0,00 | 14,4900 | 28.602 | 414 | 28.602 | |||
| 2012-02-06 | 2011-12-22 | 4 | TURNER DANIEL K III | OREX | Common Stock | I | 1,4500 | 28.602 | 41 | 377.958 | ||||
| 2012-02-06 | 2011-12-22 | 4 | TURNER DANIEL K III | OREX | Common Stock | I | 1,4500 | 28.602 | 41 | 377.958 | ||||
| 2012-01-26 | 2012-01-25 | 4 | NARACHI MICHAEL | OREX | Stock Option (right to buy) | D | 2,58 | 900.000 | 900.000 | |||||
| 2012-01-26 | 2012-01-25 | 4 | Turner Heather D | OREX | Stock Option (right to buy) | D | 2,58 | 350.000 | 350.000 | |||||
| 2012-01-26 | 2012-01-25 | 4 | Hagan Joseph P | OREX | Stock Option (right to buy) | D | 2,58 | 350.000 | 350.000 | |||||
| 2012-01-26 | 2012-01-25 | 4 | Booth Mark D | OREX | Stock Option (right to buy) | D | 2,58 | 280.000 | 280.000 | |||||
| 2012-01-26 | 2012-01-25 | 4 | Klassen Preston | OREX | Stock Option (right to buy) | D | 2,58 | 350.000 | 350.000 | |||||
| 2012-01-17 | 3 | Kamdar Kim P. By Domain Associates, L.L.C. | OREX | Common Stock | I | 1.963 | ||||||||
| 2011-06-06 | 2011-06-02 | 4 | POWELL MICHAEL | OREX | Stock Option (right to buy) | D | 3,18 | 20.000 | 20.000 | |||||
| 2011-06-06 | 2011-06-02 | 4 | BOCK LOUIS C | OREX | Stock Option (right to buy) | D | 3,18 | 20.000 | 20.000 | |||||
| 2011-06-06 | 2011-06-02 | 4 | LACOB JOSEPH | OREX | Stock Option (right to buy) | D | 3,18 | 20.000 | 20.000 | |||||
| 2011-06-06 | 2011-06-02 | 4 | WEBER ECKARD | OREX | Stock Option (right to buy) | D | 3,18 | 20.000 | 20.000 | |||||
| 2011-06-06 | 2011-06-02 | 4 | TURNER DANIEL K III | OREX | Stock Option (right to buy) | D | 3,18 | 20.000 | 20.000 | |||||
| 2010-08-16 | 3 | M. ARKIN (1999) LTD. Sphera Global Healthcare Management L.P. | OREX | Common Stock | I | 591.877 | ||||||||
| 2010-08-16 | 3 | M. ARKIN (1999) LTD. | OREX | Common Stock | D | 4.277.766 | ||||||||
| 2010-08-16 | 3 | SENATOR RON Sphera Global Healthcare Management L.P. | OREX | Common Stock | I | 591.877 | ||||||||
| 2010-06-01 | 3 | Klassen Preston | OREX | No securities are beneficially owned | D | 0 | ||||||||
| 2010-04-21 | 3 | DIXON WENDY L | OREX | No securities are beneficially owned | D | 0 | ||||||||
| 2010-03-02 | 3 | Honig Peter | OREX | No securities are beneficially owned | D | 0 | ||||||||
| 2009-11-18 | 2009-11-16 | 4 | DUNAYEVICH EDUARDO | OREX | Stock Option (right to buy) | D | 2,00 | -75.000 | 156.741 | |||||
| 2009-11-18 | 2009-11-16 | 4 | DUNAYEVICH EDUARDO | OREX | Common Stock | D | 7,5000 | -75.000 | -562 | 0 | ||||
| 2009-11-18 | 2009-11-16 | 4 | DUNAYEVICH EDUARDO | OREX | Common Stock | D | 2,0000 | 75.000 | 150 | 75.000 | ||||
| 2009-11-04 | 3 | Viveash Dawn | OREX | No securities are beneficially owned | D | 0 | ||||||||
| 2009-08-28 | 3 | Booth Mark D | OREX | No securities are beneficially owned | D | 0 | ||||||||
| 2009-06-08 | 3 | Scaife Michael C | OREX | No securities are beneficially owned | D | 0 | ||||||||
| 2009-06-08 | 3 | Hagan Joseph P | OREX | No securities are beneficially owned | D | 0 | ||||||||
| 2009-04-02 | 3 | NARACHI MICHAEL | OREX | No securities are beneficially owned | D | 0 | ||||||||
| 2009-03-05 | 3 | BAUM CAROL A | OREX | No securities are beneficially owned | D | 0 | ||||||||
| 2009-03-05 | 3 | KIM DENNIS D | OREX | Common Stock | D | 15.200 | ||||||||
| 2009-03-05 | 3 | PISKORSKI WALTER | OREX | No securities are beneficially owned | D | 0 | ||||||||
| 2009-03-02 | 3 | MAHAFFY PATRICK J | OREX | No securities are beneficially owned | D | 0 | ||||||||
| 2008-09-25 | 2008-09-23 | 4 | LANDBLOOM RONALD P | OREX | Common Stock (right to buy) | D | 2,00 | -5.000 | 195.000 | |||||
| 2008-09-25 | 2008-09-23 | 4 | LANDBLOOM RONALD P | OREX | Common Stock | D | 11,0100 | -5.000 | -55 | 0 | ||||
| 2008-09-25 | 2008-09-23 | 4 | LANDBLOOM RONALD P | OREX | Common Stock | D | 2,0000 | 5.000 | 10 | 5.000 | ||||
| 2007-06-26 | 3 | Turner Heather D | OREX | No securities beneficially owned | D | 0 | ||||||||
| 2007-06-26 | 2007-06-25 | 4 | Turner Heather D | OREX | Stock Option (right to purchase) | D | 15,45 | 130.000 | 130.000 | |||||
| 2007-05-03 | 2007-05-01 | 4 | SOFINNOVA VENTURE PARTNERS VI L P | OREX | Series C Preferred Stock | D | -15.411 | 0 | ||||||
| 2007-05-03 | 2007-05-01 | 4 | SOFINNOVA VENTURE PARTNERS VI L P | OREX | Series C Preferred Stock | D | -223.984 | 0 | ||||||
| 2007-05-03 | 2007-05-01 | 4 | SOFINNOVA VENTURE PARTNERS VI L P | OREX | Series C Preferred Stock | D | -1.130.507 | 0 | ||||||
| 2007-05-03 | 2007-05-01 | 4 | SOFINNOVA VENTURE PARTNERS VI L P | OREX | Series B Preferred Stock | D | -19.500 | 0 | ||||||
| 2007-05-03 | 2007-05-01 | 4 | SOFINNOVA VENTURE PARTNERS VI L P | OREX | Series B Preferred Stock | D | -283.424 | 0 | ||||||
| 2007-05-03 | 2007-05-01 | 4 | SOFINNOVA VENTURE PARTNERS VI L P | OREX | Series B Preferred Stock | D | -1.430.512 | 0 | ||||||
| 2007-05-03 | 2007-05-01 | 4 | SOFINNOVA VENTURE PARTNERS VI L P | OREX | Series A Preferred Stock | D | -28.600 | 0 | ||||||
| 2007-05-03 | 2007-05-01 | 4 | SOFINNOVA VENTURE PARTNERS VI L P | OREX | Series A Preferred Stock | D | -415.688 | 0 | ||||||
| 2007-05-03 | 2007-05-01 | 4 | SOFINNOVA VENTURE PARTNERS VI L P | OREX | Series A Preferred Stock | D | -2.098.085 | 0 | ||||||
| 2007-05-03 | 2007-05-01 | 4 | SOFINNOVA VENTURE PARTNERS VI L P | OREX | Common Stock | D | 7.705 | 31.755 | ||||||
| 2007-05-03 | 2007-05-01 | 4 | SOFINNOVA VENTURE PARTNERS VI L P | OREX | Common Stock | D | 111.992 | 461.548 | ||||||
| 2007-05-03 | 2007-05-01 | 4 | SOFINNOVA VENTURE PARTNERS VI L P | OREX | Common Stock | D | 565.253 | 2.329.551 | ||||||
| 2007-05-03 | 2007-05-01 | 4 | SOFINNOVA VENTURE PARTNERS VI L P | OREX | Common Stock | D | 9.750 | 24.050 | ||||||
| 2007-05-03 | 2007-05-01 | 4 | SOFINNOVA VENTURE PARTNERS VI L P | OREX | Common Stock | D | 141.712 | 349.556 | ||||||
| 2007-05-03 | 2007-05-01 | 4 | SOFINNOVA VENTURE PARTNERS VI L P | OREX | Common Stock | D | 715.256 | 1.764.298 | ||||||
| 2007-05-03 | 2007-05-01 | 4 | SOFINNOVA VENTURE PARTNERS VI L P | OREX | Common Stock | D | 14.300 | 14.300 | ||||||
| 2007-05-03 | 2007-05-01 | 4 | SOFINNOVA VENTURE PARTNERS VI L P | OREX | Common Stock | D | 207.844 | 207.844 | ||||||
| 2007-05-03 | 2007-05-01 | 4 | SOFINNOVA VENTURE PARTNERS VI L P | OREX | Common Stock | D | 1.049.042 | 1.049.042 | ||||||
| 2007-04-25 | 3 | COWLEY MICHAEL A | OREX | Common Stock | D | 216.500 | ||||||||
| 2007-04-25 | 3 | MCKINNEY ANTHONY A | OREX | Common Stock | D | 14.583 | ||||||||
| 2007-04-25 | 3 | WEBER ECKARD | OREX | Common Stock | D | 650.000 |
P
Åbent marked eller privat køb af ikke-afledte eller afledte værdipapirer
S
Åbent marked eller privat salg af ikke-afledte eller afledte værdipapirer
A
Tildeling, tildeling eller anden erhvervelse af værdipapirer fra virksomheden (såsom en option)
C
Konvertering af derivat
D
Salg eller overførsel af værdipapirer tilbage til virksomheden
F
Betaling af udnyttelseskurs eller skatteforpligtelse ved brug af en del af værdipapirer modtaget fra selskabet
G
Gave af værdipapirer af eller til insideren
K
Aktieswaps og lignende sikringstransaktioner
M
Udnyttelse eller konvertering af afledt værdipapir modtaget fra virksomheden (såsom en option)
V
En transaktion rapporteret frivilligt på formular 4
J
Andet (ledsaget af en fodnote, der beskriver transaktionen)
