| Insideraktier | 19.980.267 shares |
Insider-stemningsscore
Insider Sentiment Score viser, at virksomhederne bliver købt af virksomheders insidere.
Det er resultatet af en sofistikeret, multi-faktor kvantitativ model, der identificerer virksomheder med de højeste niveauer af insider-akkumulering. Scoringsmodellen bruger en kombination af nettoantallet af insidere, der har købt de foregående 90 dage, det samlede antal aktier købt som en procentdel af float og det samlede antal aktier ejet af insidere. Tallet går fra 0 til 100, hvor højere tal indikerer et højere niveau af akkumulering for sine jævnaldrende, og 50 er gennemsnittet.
Opdateringsfrekvens: Dagligt
Se Insiders Top Picks, som giver en liste over virksomheder med den højeste insider-akkumulering.
Officers sentiment score
Officer Sentiment Score finder virksomheder, der bliver købt af Corporate Officers.
Per definition er Corporate Officers Corporate Insiders, men i modsætning til nogle af de andre Insiders (10 % aktionærer og bestyrelsesmedlemmer), arbejder officerer for virksomheden på daglig basis, og de bruger deres egne penge, når de handler . (10 % aktionærer og bestyrelsesmedlemmer er ofte fondsforvaltere, der administrerer andres penge.) Som sådan er insiderhandler foretaget af embedsmænd meget mere betydningsfulde og bør behandles passende.
Ligesom Insider Sentiment Score er Officer Sentiment Score resultatet af en sofistikeret, multi-faktor kvantitativ model, der identificerer virksomheder med de højeste niveauer af officerakkumulering.
Opdateringsfrekvens: Dagligt
Se Insiders Top Picks, som giver en liste over virksomheder med højeste insider-stemning.
Nøgle Insider Metrics
Dette kort viser, hvordan virksomheden rangerer langs forskellige insider-metrics. Percentilrangen viser, hvordan denne virksomhed sammenligner sig med andre virksomheder på de amerikanske markeder. Højere placeringer er tegn på bedre situationer.
For eksempel er det generelt accepteret, at insider-køb er en positiv indikator, så virksomheder med flere insider-køb vil rangere højere end virksomheder med mindre insider-køb (eller endda insider-salg).
Netto antal insidere, der køber (rang)
N/A
Netto antal insidere, der køber, er det samlede antal insiders, der køber minus det samlede antal insiders, der har solgt inden for de sidste 90 dage. Percentilrangen vises her (spænder fra 0 til 100%).
Procent af float købt af insidere (rangering)
N/A
Procent af float købt af insidere er det samlede antal aktier købt af insidere minus det samlede antal aktier solgt af insidere inden for de sidste 90 dage, divideret med den samlede float og ganget med 100.
Insiderhandelsdiagram
Cascadian Therapeutics, Inc. insiderhandler er vist i følgende diagram. Insidere er embedsmænd, direktører eller betydelige investorer i en virksomhed. Generelt er det generelt ulovligt for insidere at foretage handler i deres virksomheder baseret på væsentlige, ikke-offentlige oplysninger. Dette betyder ikke, at det er ulovligt for dem at handle i deres egne virksomheder. De skal dog rapportere alle handler til SEC via en formular 4.
Insiderliste og lønsomhedsmålinger
Denne tabel viser listen over kendte insidere og genereres automatisk fra arkiveringer, der er videregivet til SEC. Ud over navnene, den seneste titel og direktør, officer eller 10 % ejerbetegnelse giver vi de seneste offentliggjorte besiddelser. Derudover giver vi, når det er muligt, den historiske handelspræstation for insideren. Den historiske handelspræstation er et vægtet gennemsnit af præstationen af faktiske købstransaktioner på det åbne marked foretaget af insideren. For mere information om, hvordan dette beregnes, se dette YouTube-webinar.
See our leaderboard of most profitable insider traders.
| Insider | Gennemsnitlig fortjeneste (%) | Aktier Ejet |
Dele Justeret |
|---|
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Track Records af insiderkøb - Kortsigtet profitanalyse
I dette afsnit analyserer vi rentabiliteten af ethvert uplanlagt insiderkøb i åbent marked foretaget i CASC / Cascadian Therapeutics, Inc.. Denne analyse hjælper med at forstå, om insideren konsekvent genererer unormale afkast og er værd at følge. Denne analyse er for et år efter hver handel, og resultaterne er teoretiske .
Følgende tabel viser de seneste køb på det åbne marked, der ikke var en del af en automatisk handelsplan.
Justeret pris er den split-justerede pris. Adjusted Shares er de split-justerede aktier.
Track Records af insidersalg - Kortsigtet tabsanalyse
I dette afsnit analyserer vi den kortsigtede undgåelse af tab af ethvert uplanlagt insidersalg på åbent marked, der foretages i CASC / Cascadian Therapeutics, Inc.. Et konsekvent mønster af tabsforebyggelse kan tyde på, at fremtidige salgstransaktioner kan forudsige prisfald. Denne analyse er for et år efter hver handel, og resultaterne er teoretiske .
Følgende tabel viser de seneste salg på det åbne marked, der ikke var en del af en automatisk handelsplan.
Justeret pris er den split-justerede pris. Adjusted Shares er de split-justerede aktier.
Transaktionshistorik
Klik på linkikonet for at se den fulde transaktionshistorik. Transaktioner, der rapporteres som en del af en automatisk handelsplan 10b5-1, vil have et X i kolonnen markeret 10b-5.
| Fil Dato |
Handle Dato |
Form | Insider | Ticker | Sikkerhedstitel | Kode | Direkte | Dyrke motion Pris |
Enhed Pris |
Enheder Ændret |
Værdi Ændret (1K) |
Tilbage Muligheder |
Tilbage Aktier |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Restricted Stock Units | D | -199.000 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Restricted Stock Units | D | -16.500 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Restricted Stock Units | D | -11.300 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Stock Option (Right to buy) | D | 3,99 | -75.000 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Stock Option (Right to buy) | D | 4,64 | -51.200 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Stock Option (Right to buy) | D | 6,90 | -50.000 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Stock Option (Right to buy) | D | 21,06 | -41.667 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Stock Option (Right to buy) | D | 10,56 | -16.667 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Stock Option (Right to buy) | D | 10,44 | -25.000 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Stock Option (Right to buy) | D | 28,44 | -8.334 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Stock Option (Right to buy) | D | 19,92 | -8.334 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Stock Option (Right to buy) | D | 41,52 | -8.334 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Stock Option (Right to buy) | D | 19,86 | -6.667 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | EASTLAND JULIA MARIE | CASC | Common Stock | D | -5.237 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | HENNEY CHRISTOPHER S | CASC | Restricted Stock Units | D | -13.927 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | HENNEY CHRISTOPHER S | CASC | Stock Option (Right to buy) | D | 6,36 | -25.000 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | HENNEY CHRISTOPHER S | CASC | Common Stock | D | -60.185 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Christianson Gary | CASC | Restricted Stock Units | D | -164.500 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Christianson Gary | CASC | Restricted Stock Units | D | -15.000 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Christianson Gary | CASC | Restricted Stock Units | D | -11.300 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Christianson Gary | CASC | Stock Option (Right to buy) | D | 3,99 | -68.000 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Christianson Gary | CASC | Stock Option (Right to buy) | D | 4,64 | -51.200 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Christianson Gary | CASC | Stock Option (Right to buy) | D | 6,90 | -41.667 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Christianson Gary | CASC | Stock Option (Right to buy) | D | 21,06 | -41.667 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Christianson Gary | CASC | Stock Option (Right to buy) | D | 10,56 | -16.667 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Christianson Gary | CASC | Stock Option (Right to buy) | D | 10,44 | -25.000 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Christianson Gary | CASC | Stock Option (Right to buy) | D | 28,44 | -8.334 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Christianson Gary | CASC | Stock Option (Right to buy) | D | 19,92 | -8.334 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Christianson Gary | CASC | Stock Option (Right to buy) | D | 41,52 | -8.334 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Christianson Gary | CASC | Common Stock | D | -6.515 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Growth Equity Opportunities IV, LLC | CASC | Common Stock | D | -10.882.574 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | BASKETT FOREST See Note 2 | CASC | Common Stock | I | -10.882.574 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Myers Scott Dunseth | CASC | Restricted Stock Units | D | -250.000 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Myers Scott Dunseth | CASC | Restricted Stock Units | D | -6.300 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Myers Scott Dunseth | CASC | Restricted Stock Units | D | -15.500 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Myers Scott Dunseth | CASC | Restricted Stock Units | D | -42.000 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Myers Scott Dunseth | CASC | Stock Option (Right to buy) | D | 3,99 | -60.000 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Myers Scott Dunseth | CASC | Stock Option (Right to buy) | D | 4,64 | -190.000 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Myers Scott Dunseth | CASC | Stock Option (Right to buy) | D | 7,08 | -474.810 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Myers Scott Dunseth | CASC | Common Stock | D | -56.787 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | SPIEGELMAN DANIEL K | CASC | Restricted Stock Units | D | -13.927 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | SPIEGELMAN DANIEL K | CASC | Common Stock | D | -21.006 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Azelby Robert | CASC | Restricted Stock Units | D | -13.927 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Azelby Robert | CASC | Restricted Stock Units | D | -12.437 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Florence Anthony A. Jr. See Note 2 | CASC | Common Stock | I | -10.882.574 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | PETERSON SCOTT ROBERT | CASC | Restricted Stock Units | D | -155.500 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | PETERSON SCOTT ROBERT | CASC | Restricted Stock Units | D | -14.000 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | PETERSON SCOTT ROBERT | CASC | Restricted Stock Units | D | -11.300 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | PETERSON SCOTT ROBERT | CASC | Stock Option (Right to buy) | D | 3,99 | -65.000 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | PETERSON SCOTT ROBERT | CASC | Stock Option (Right to buy) | D | 4,64 | -51.200 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | PETERSON SCOTT ROBERT | CASC | Stock Option (Right to buy) | D | 6,90 | -54.167 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | PETERSON SCOTT ROBERT | CASC | Stock Option (Right to buy) | D | 21,06 | -41.667 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | PETERSON SCOTT ROBERT | CASC | Stock Option (Right to buy) | D | 10,44 | -25.000 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | PETERSON SCOTT ROBERT | CASC | Stock Option (Right to buy) | D | 10,56 | -25.000 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | PETERSON SCOTT ROBERT | CASC | Stock Option (Right to buy) | D | 28,44 | -8.334 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | PETERSON SCOTT ROBERT | CASC | Stock Option (Right to buy) | D | 19,92 | -8.334 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | PETERSON SCOTT ROBERT | CASC | Stock Option (Right to buy) | D | 41,52 | -8.334 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | PETERSON SCOTT ROBERT | CASC | Common Stock | D | -3.639 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | MAKOWER JOSHUA See Note 2 | CASC | Common Stock | I | -10.882.574 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | MOTT DAVID M See Note 2 | CASC | Common Stock | I | -10.882.574 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Sakoda Jon See Note 2 | CASC | Common Stock | I | -10.882.574 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | SANDELL SCOTT D See Note 2 | CASC | Common Stock | I | -10.882.574 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Sonsini Peter W. See Note 2 | CASC | Common Stock | I | -10.882.574 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Viswanathan Ravi See Note 2 | CASC | Common Stock | I | -10.882.574 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Fyfe Gwen A. | CASC | Restricted Stock Units | D | -13.927 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Fyfe Gwen A. | CASC | Common Stock | D | -10.125 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | LOVE TED W | CASC | Restricted Stock Units | D | -13.927 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | LOVE TED W | CASC | Common Stock | D | -37.394 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | James Steven P | CASC | Restricted Stock Units | D | -13.927 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | James Steven P | CASC | Common Stock | D | -13.677 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Restricted Stock Units | D | -130.000 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Restricted Stock Units | D | -12.000 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Restricted Stock Units | D | -7.800 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Stock Option (Right to buy) | D | 3,99 | -50.000 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Stock Option (Right to buy) | D | 4,64 | -35.100 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Stock Option (Right to buy) | D | 6,90 | -20.834 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Stock Option (Right to buy) | D | 6,90 | -8.334 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Stock Option (Right to buy) | D | 21,06 | -5.834 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Stock Option (Right to buy) | D | 28,44 | -1.250 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Stock Option (Right to buy) | D | 10,56 | -1.250 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Stock Option (Right to buy) | D | 35,88 | -2.500 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Stock Option (Right to buy) | D | 10,44 | -2.500 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Stock Option (Right to buy) | D | 41,52 | -334 | 0 | |||||
| 2018-03-13 | 2018-03-09 | 4 | Walker Luke Nathaniel | CASC | Common Stock | D | -10.315 | 0 | ||||||
| 2018-03-13 | 2018-03-09 | 4 | BARRIS PETER J See Note 2 | CASC | Common Stock | I | -10.882.574 | 0 | ||||||
| 2018-02-22 | 2018-02-20 | 4 | Growth Equity Opportunities IV, LLC | CASC | Series E Preferred Stock | D | 3,30 | -1.818.000 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | Growth Equity Opportunities IV, LLC | CASC | Common Stock | D | 3,3000 | 1.818.000 | 5.999 | 10.882.574 | ||||
| 2018-02-22 | 2018-02-20 | 4 | BARRIS PETER J See Note 1 | CASC | Series E Preferred Stock | I | 3,30 | -1.818.000 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | BARRIS PETER J See Note 1 | CASC | Common Stock | I | 3,3000 | 1.818.000 | 5.999 | 10.882.574 | ||||
| 2018-02-22 | 2018-02-20 | 4 | BASKETT FOREST See Note 1 | CASC | Series E Preferred Stock | I | 3,30 | -1.818.000 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | BASKETT FOREST See Note 1 | CASC | Common Stock | I | 3,3000 | 1.818.000 | 5.999 | 10.882.574 | ||||
| 2018-02-22 | 2018-02-20 | 4 | Florence Anthony A. Jr. See Note 1 | CASC | Series E Preferred Stock | I | 3,30 | -1.818.000 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | Florence Anthony A. Jr. See Note 1 | CASC | Common Stock | I | 3,3000 | 1.818.000 | 5.999 | 10.882.574 | ||||
| 2018-02-22 | 2018-02-20 | 4 | MAKOWER JOSHUA See Note 1 | CASC | Series E Preferred Stock | I | 3,30 | -1.818.000 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | MAKOWER JOSHUA See Note 1 | CASC | Common Stock | I | 3,3000 | 1.818.000 | 5.999 | 10.882.574 | ||||
| 2018-02-22 | 2018-02-20 | 4 | MOTT DAVID M See Note 1 | CASC | Series E Preferred Stock | I | 3,30 | -1.818.000 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | MOTT DAVID M See Note 1 | CASC | Common Stock | I | 3,3000 | 1.818.000 | 5.999 | 10.882.574 | ||||
| 2018-02-22 | 2018-02-20 | 4 | Sakoda Jon See Note 1 | CASC | Series E Preferred Stock | I | 3,30 | -1.818.000 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | Sakoda Jon See Note 1 | CASC | Common Stock | I | 3,3000 | 1.818.000 | 5.999 | 10.882.574 | ||||
| 2018-02-22 | 2018-02-20 | 4 | SANDELL SCOTT D See Note 1 | CASC | Series E Preferred Stock | I | 3,30 | -1.818.000 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | SANDELL SCOTT D See Note 1 | CASC | Common Stock | I | 3,3000 | 1.818.000 | 5.999 | 10.882.574 | ||||
| 2018-02-22 | 2018-02-20 | 4 | Sonsini Peter W. See Note 1 | CASC | Series E Preferred Stock | I | 3,30 | -1.818.000 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | Sonsini Peter W. See Note 1 | CASC | Common Stock | I | 3,3000 | 1.818.000 | 5.999 | 10.882.574 | ||||
| 2018-02-22 | 2018-02-20 | 4 | Viswanathan Ravi See Note 1 | CASC | Series E Preferred Stock | I | 3,30 | -1.818.000 | 0 | |||||
| 2018-02-22 | 2018-02-20 | 4 | Viswanathan Ravi See Note 1 | CASC | Common Stock | I | 3,3000 | 1.818.000 | 5.999 | 10.882.574 | ||||
| 2018-02-02 | 2018-02-01 | 4 | Christianson Gary | CASC | Restricted Share Unit (RSU) | D | 164.500 | 164.500 | ||||||
| 2018-02-02 | 2018-02-01 | 4 | EASTLAND JULIA MARIE | CASC | Restricted Share Unit (RSU) | D | 199.000 | 199.000 | ||||||
| 2018-02-02 | 2018-02-01 | 4 | Myers Scott Dunseth | CASC | Restricted Share Unit (RSU) | D | 250.000 | 250.000 | ||||||
| 2018-02-02 | 2018-02-01 | 4 | PETERSON SCOTT ROBERT | CASC | Restricted Share Unit (RSU) | D | 155.500 | 155.500 | ||||||
| 2018-02-02 | 2018-02-01 | 4 | Walker Luke Nathaniel | CASC | Restricted Share Unit (RSU) | D | 130.000 | 130.000 | ||||||
| 2018-01-16 | 2018-01-11 | 4 | Christianson Gary | CASC | Restricted Share Unit (RSU) | D | -2.825 | 8.475 | ||||||
| 2018-01-16 | 2018-01-11 | 4 | Christianson Gary | CASC | Common Stock | D | 3,9200 | -923 | -4 | 6.515 | ||||
| 2018-01-16 | 2018-01-11 | 4 | Christianson Gary | CASC | Common Stock | D | 2.825 | 7.438 | ||||||
| 2018-01-16 | 2018-01-11 | 4 | EASTLAND JULIA MARIE | CASC | Restricted Share Unit (RSU) | D | -2.825 | 8.475 | ||||||
| 2018-01-16 | 2018-01-11 | 4 | EASTLAND JULIA MARIE | CASC | Common Stock | D | 3,9200 | -923 | -4 | 5.237 | ||||
| 2018-01-16 | 2018-01-11 | 4 | EASTLAND JULIA MARIE | CASC | Common Stock | D | 2.825 | 6.160 | ||||||
| 2018-01-16 | 2018-01-11 | 4 | Myers Scott Dunseth | CASC | Restricted Share Unit (RSU) | D | -10.500 | 31.500 | ||||||
| 2018-01-16 | 2018-01-11 | 4 | Myers Scott Dunseth | CASC | Common Stock | D | 3,9200 | -3.429 | -13 | 56.787 | ||||
| 2018-01-16 | 2018-01-11 | 4 | Myers Scott Dunseth | CASC | Common Stock | D | 10.500 | 60.216 | ||||||
| 2018-01-16 | 2018-01-11 | 4 | PETERSON SCOTT ROBERT | CASC | Restricted Share Unit (RSU) | D | -2.825 | 8.475 | ||||||
| 2018-01-16 | 2018-01-11 | 4 | PETERSON SCOTT ROBERT | CASC | Common Stock | D | 3,9200 | -923 | -4 | 3.639 | ||||
| 2018-01-16 | 2018-01-11 | 4 | PETERSON SCOTT ROBERT | CASC | Common Stock | D | 2.825 | 4.562 | ||||||
| 2018-01-16 | 2018-01-11 | 4 | Walker Luke Nathaniel | CASC | Restricted Share Unit (RSU) | D | -1.950 | 5.850 | ||||||
| 2018-01-16 | 2018-01-11 | 4 | Walker Luke Nathaniel | CASC | Common Stock | D | 3,9200 | -637 | -2 | 5.303 | ||||
| 2018-01-16 | 2018-01-11 | 4 | Walker Luke Nathaniel | CASC | Common Stock | D | 1.950 | 5.940 | ||||||
| 2017-11-13 | 2017-11-10 | 4 | Myers Scott Dunseth | CASC | Restricted Share Unit (RSU) | D | 6.300 | 6.300 | ||||||
| 2017-09-26 | 2017-09-24 | 4 | HENNEY CHRISTOPHER S | CASC | Restricted Share Unit (RSU) | D | -2.375 | 0 | ||||||
| 2017-09-26 | 2017-09-24 | 4 | HENNEY CHRISTOPHER S | CASC | Common Stock | D | 3,9400 | -594 | -2 | 60.185 | ||||
| 2017-09-26 | 2017-09-24 | 4 | HENNEY CHRISTOPHER S | CASC | Common Stock | D | 2.375 | 60.779 | ||||||
| 2017-09-26 | 2017-09-24 | 4 | James Steven P | CASC | Restricted Share Unit (RSU) | D | -2.375 | 0 | ||||||
| 2017-09-26 | 2017-09-24 | 4 | James Steven P | CASC | Common Stock | D | 3,9400 | -594 | -2 | 13.677 | ||||
| 2017-09-26 | 2017-09-24 | 4 | James Steven P | CASC | Common Stock | D | 2.375 | 14.271 | ||||||
| 2017-09-26 | 2017-09-24 | 4 | LOVE TED W | CASC | Restricted Share Unit (RSU) | D | -2.375 | 0 | ||||||
| 2017-09-26 | 2017-09-24 | 4 | LOVE TED W | CASC | Common Stock | D | 3,9400 | -594 | -2 | 37.394 | ||||
| 2017-09-26 | 2017-09-24 | 4 | LOVE TED W | CASC | Common Stock | D | 2.375 | 37.988 | ||||||
| 2017-09-26 | 2017-09-24 | 4 | SPIEGELMAN DANIEL K | CASC | Restricted Share Unit (RSU) | D | -2.375 | 0 | ||||||
| 2017-09-26 | 2017-09-24 | 4 | SPIEGELMAN DANIEL K | CASC | Common Stock | D | 3,9400 | -594 | -2 | 21.006 | ||||
| 2017-09-26 | 2017-09-24 | 4 | SPIEGELMAN DANIEL K | CASC | Common Stock | D | 2.375 | 21.600 | ||||||
| 2017-09-20 | 2017-09-18 | 4 | Myers Scott Dunseth | CASC | Restricted Share Unit (RSU) | D | 15.500 | 15.500 | ||||||
| 2017-09-20 | 2017-09-18 | 4 | Myers Scott Dunseth | CASC | Stock Option (right to buy) | D | 3,99 | 60.000 | 60.000 | |||||
| 2017-09-20 | 2017-09-18 | 4 | Christianson Gary | CASC | Restricted Share Unit (RSU) | D | 15.000 | 15.000 | ||||||
| 2017-09-20 | 2017-09-18 | 4 | Christianson Gary | CASC | Stock Option (right to buy) | D | 3,99 | 68.000 | 68.000 | |||||
| 2017-09-20 | 2017-09-18 | 4 | EASTLAND JULIA MARIE | CASC | Restricted Share Unit (RSU) | D | 16.500 | 16.500 | ||||||
| 2017-09-20 | 2017-09-18 | 4 | EASTLAND JULIA MARIE | CASC | Stock Option (right to buy) | D | 3,99 | 75.000 | 75.000 | |||||
| 2017-09-20 | 2017-09-18 | 4 | Walker Luke Nathaniel | CASC | Restricted Share Unit (RSU) | D | 12.000 | 12.000 | ||||||
| 2017-09-20 | 2017-09-18 | 4 | Walker Luke Nathaniel | CASC | Stock Option (right to buy) | D | 3,99 | 50.000 | 50.000 | |||||
| 2017-09-20 | 2017-09-18 | 4 | PETERSON SCOTT ROBERT | CASC | Restricted Share Unit (RSU) | D | 14.000 | 14.000 | ||||||
| 2017-09-20 | 2017-09-18 | 4 | PETERSON SCOTT ROBERT | CASC | Stock Option (right to buy) | D | 3,99 | 65.000 | 65.000 | |||||
| 2017-08-14 | 2017-08-11 | 4 | Myers Scott Dunseth | CASC | Common Stock | D | 3,7350 | 5.500 | 21 | 49.716 | ||||
| 2017-06-27 | 2017-06-24 | 4 | SPIEGELMAN DANIEL K | CASC | Restricted Share Unit (RSU) | D | -9.058 | 0 | ||||||
| 2017-06-27 | 2017-06-24 | 4 | SPIEGELMAN DANIEL K | CASC | Common Stock | D | 3,7800 | -2.265 | -9 | 19.225 | ||||
| 2017-06-27 | 2017-06-24 | 4 | SPIEGELMAN DANIEL K | CASC | Common Stock | D | 9.058 | 21.490 | ||||||
| 2017-06-27 | 2017-06-24 | 4 | Fyfe Gwen A. | CASC | Restricted Share Unit (RSU) | D | -9.058 | 0 | ||||||
| 2017-06-27 | 2017-06-24 | 4 | Fyfe Gwen A. | CASC | Common Stock | D | 3,7800 | -2.265 | -9 | 10.125 | ||||
| 2017-06-27 | 2017-06-24 | 4 | Fyfe Gwen A. | CASC | Common Stock | D | 9.058 | 12.390 | ||||||
| 2017-06-27 | 2017-06-24 | 4 | HENNEY CHRISTOPHER S | CASC | Restricted Share Unit (RSU) | D | -9.058 | 0 | ||||||
| 2017-06-27 | 2017-06-24 | 4 | HENNEY CHRISTOPHER S | CASC | Common Stock | D | 3,7800 | -2.265 | -9 | 58.404 | ||||
| 2017-06-27 | 2017-06-24 | 4 | HENNEY CHRISTOPHER S | CASC | Common Stock | D | 9.058 | 60.669 | ||||||
| 2017-06-27 | 2017-06-24 | 4 | James Steven P | CASC | Restricted Share Unit (RSU) | D | -9.058 | 0 | ||||||
| 2017-06-27 | 2017-06-24 | 4 | James Steven P | CASC | Common Stock | D | 3,7800 | -2.265 | -9 | 11.896 | ||||
| 2017-06-27 | 2017-06-24 | 4 | James Steven P | CASC | Common Stock | D | 9.058 | 14.161 | ||||||
| 2017-06-27 | 2017-06-24 | 4 | LOVE TED W | CASC | Restricted Share Unit (RSU) | D | -9.058 | 0 | ||||||
| 2017-06-27 | 2017-06-24 | 4 | LOVE TED W | CASC | Common Stock | D | 3,7800 | -2.265 | -9 | 35.613 | ||||
| 2017-06-27 | 2017-06-24 | 4 | LOVE TED W | CASC | Common Stock | D | 9.058 | 37.878 | ||||||
| 2017-06-13 | 2017-06-09 | 4 | Fyfe Gwen A. | CASC | Restricted Share Unit (RSU) | D | 13.927 | 13.927 | ||||||
| 2017-06-13 | 2017-06-12 | 4 | HENNEY CHRISTOPHER S | CASC | Restricted Share Unit (RSU) | D | -2.148 | 0 | ||||||
| 2017-06-13 | 2017-06-12 | 4 | HENNEY CHRISTOPHER S | CASC | Common Stock | D | 3,3400 | -537 | -2 | 51.611 | ||||
| 2017-06-13 | 2017-06-12 | 4 | HENNEY CHRISTOPHER S | CASC | Common Stock | D | 2.148 | 52.148 | ||||||
| 2017-06-13 | 2017-06-09 | 4 | HENNEY CHRISTOPHER S | CASC | Restricted Share Unit (RSU) | D | 13.927 | 13.927 | ||||||
| 2017-06-13 | 2017-06-12 | 4 | James Steven P | CASC | Restricted Share Unit (RSU) | D | -2.148 | 0 | ||||||
| 2017-06-13 | 2017-06-12 | 4 | James Steven P | CASC | Common Stock | D | 3,3400 | -537 | -2 | 5.103 | ||||
| 2017-06-13 | 2017-06-12 | 4 | James Steven P | CASC | Common Stock | D | 2.148 | 5.640 | ||||||
| 2017-06-13 | 2017-06-09 | 4 | James Steven P | CASC | Restricted Share Unit (RSU) | D | 13.927 | 13.927 | ||||||
| 2017-06-13 | 2017-06-12 | 4 | LOVE TED W | CASC | Restricted Share Unit (RSU) | D | -2.148 | 0 | ||||||
| 2017-06-13 | 2017-06-12 | 4 | LOVE TED W | CASC | Common Stock | D | 3,3400 | -537 | -2 | 28.820 | ||||
| 2017-06-13 | 2017-06-12 | 4 | LOVE TED W | CASC | Common Stock | D | 2.148 | 29.357 | ||||||
| 2017-06-13 | 2017-06-09 | 4 | LOVE TED W | CASC | Restricted Share Unit (RSU) | D | 13.927 | 13.927 | ||||||
| 2017-06-13 | 2017-06-12 | 4 | SPIEGELMAN DANIEL K | CASC | Restricted Share Unit (RSU) | D | -2.148 | 0 | ||||||
| 2017-06-13 | 2017-06-12 | 4 | SPIEGELMAN DANIEL K | CASC | Common Stock | D | 3,3400 | -537 | -2 | 12.432 | ||||
| 2017-06-13 | 2017-06-12 | 4 | SPIEGELMAN DANIEL K | CASC | Common Stock | D | 2.148 | 12.969 | ||||||
| 2017-06-13 | 2017-06-09 | 4 | SPIEGELMAN DANIEL K | CASC | Restricted Share Unit (RSU) | D | 13.927 | 13.927 | ||||||
| 2017-06-13 | 2017-06-09 | 4 | Azelby Robert | CASC | Restricted Share Unit (RSU) | D | 13.927 | 13.927 | ||||||
| 2017-05-16 | 2017-05-12 | 4 | Myers Scott Dunseth | CASC | Common Stock | D | 3,9970 | 2.800 | 11 | 44.216 | ||||
| 2017-04-04 | 3 | Azelby Robert | CASC | No securities were benefically held | D | 0 | ||||||||
| 2017-04-04 | 2017-04-03 | 4 | Azelby Robert | CASC | Restricted Stock Unit (RSU) | D | 12.437 | 12.437 | ||||||
| 2017-04-04 | 2017-03-31 | 4 | Myers Scott Dunseth | CASC | Common Stock | D | 4,1143 | 2.000 | 8 | 41.416 | ||||
| 2017-03-30 | 2017-03-28 | 4 | Fyfe Gwen A. | CASC | Common Stock | D | 4,1158 | 1.666 | 7 | 3.332 | ||||
| 2017-03-21 | 2017-03-20 | 4 | Myers Scott Dunseth | CASC | Common Stock | D | 3,9271 | 1.000 | 4 | 39.416 | ||||
| 2017-03-20 | 3 | Walker Luke Nathaniel | CASC | Common Stock | D | 7.980 | ||||||||
| 2017-03-20 | 3 | Walker Luke Nathaniel | CASC | Common Stock | D | 7.980 | ||||||||
| 2017-03-14 | 2017-03-12 | 4 | James Steven P | CASC | Restricted Share Unit (RSU) | D | -4.656 | 0 | ||||||
| 2017-03-14 | 2017-03-12 | 4 | James Steven P | CASC | Common Stock | D | 4,3500 | -1.164 | -5 | 3.492 | ||||
| 2017-03-14 | 2017-03-12 | 4 | James Steven P | CASC | Common Stock | D | 4.656 | 4.656 | ||||||
| 2017-02-10 | 2016-06-06 | 5 | HENNEY CHRISTOPHER S | CASC | Restricted Share Unit (RSU) | D | -2.723 | 0 | ||||||
| 2017-02-10 | 2016-06-06 | 5 | HENNEY CHRISTOPHER S | CASC | Common Stock | D | 7,3800 | -681 | -5 | 50.000 | ||||
| 2017-02-10 | 2016-06-06 | 5 | HENNEY CHRISTOPHER S | CASC | Common Stock | D | 2.723 | 50.861 | ||||||
| 2017-02-10 | 2016-06-06 | 5 | Jackson Richard L. | CASC | Restricted Share Unit (RSU) | D | -2.723 | 0 | ||||||
| 2017-02-10 | 2016-06-06 | 5 | Jackson Richard L. | CASC | Common Stock | D | 7,3800 | -681 | -5 | 11.968 | ||||
| 2017-02-10 | 2016-06-06 | 5 | Jackson Richard L. | CASC | Common Stock | D | 2.723 | 12.649 | ||||||
| 2017-02-10 | 2016-06-06 | 5 | LOVE TED W | CASC | Restricted Share Unit (RSU) | D | -2.723 | 0 | ||||||
| 2017-02-10 | 2016-06-06 | 5 | LOVE TED W | CASC | Common Stock | D | 7,3800 | -681 | -5 | 27.209 | ||||
| 2017-02-10 | 2016-06-06 | 5 | LOVE TED W | CASC | Common Stock | D | 2.723 | 27.890 | ||||||
| 2017-02-10 | 2016-06-06 | 5 | SPIEGELMAN DANIEL K | CASC | Restricted Share Unit (RSU) | D | -2.723 | 0 | ||||||
| 2017-02-10 | 2016-06-06 | 5 | SPIEGELMAN DANIEL K | CASC | Common Stock | D | 7,3800 | -681 | -5 | 10.821 | ||||
| 2017-02-10 | 2016-06-06 | 5 | SPIEGELMAN DANIEL K | CASC | Common Stock | D | 2.723 | 11.502 | ||||||
| 2017-02-03 | 2017-02-02 | 4 | LOVE TED W | CASC | Common Stock | D | 4,2400 | 23.000 | 98 | 27.209 | ||||
| 2017-02-01 | 3 | BARRIS PETER J See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | BARRIS PETER J See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | BASKETT FOREST See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | BASKETT FOREST See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | SANDELL SCOTT D See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | SANDELL SCOTT D See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | MOTT DAVID M See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | MOTT DAVID M See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | MAKOWER JOSHUA See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | MAKOWER JOSHUA See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | Viswanathan Ravi See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | Viswanathan Ravi See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | Sonsini Peter W. See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | Sonsini Peter W. See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | Sakoda Jon See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | Sakoda Jon See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | Florence Anthony A. Jr. See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | Florence Anthony A. Jr. See Note 1 | CASC | Common Stock | I | 18.129.148 | ||||||||
| 2017-02-01 | 3 | New Enterprise Associates 15, L.P. | CASC | Common Stock | D | 18.129.148 | ||||||||
| 2017-02-01 | 3 | New Enterprise Associates 15, L.P. | CASC | Common Stock | D | 18.129.148 | ||||||||
| 2017-02-01 | 3 | New Enterprise Associates 15, L.P. | CASC | Common Stock | D | 18.129.148 | ||||||||
| 2017-02-01 | 3 | New Enterprise Associates 15, L.P. | CASC | Common Stock | D | 18.129.148 | ||||||||
| 2017-02-01 | 3 | New Enterprise Associates 15, L.P. | CASC | Common Stock | D | 18.129.148 | ||||||||
| 2017-02-01 | 2017-01-30 | 4 | HENNEY CHRISTOPHER S | CASC | Common Stock | D | 4,1057 | 25.324 | 104 | 50.000 | ||||
| 2017-01-31 | 2017-01-27 | 4 | Myers Scott Dunseth | CASC | Common Stock | D | 3,7580 | 20.500 | 77 | 38.416 | ||||
| 2017-01-13 | 2017-01-11 | 4 | Myers Scott Dunseth | CASC | Restricted Share Unit (RSU) | D | 42.000 | 42.000 | ||||||
| 2017-01-13 | 2017-01-11 | 4 | Myers Scott Dunseth | CASC | Stock Option (right to buy) | D | 4,64 | 190.000 | 190.000 | |||||
| 2017-01-13 | 2017-01-11 | 4 | Christianson Gary | CASC | Restricted Share Unit (RSU) | D | 11.300 | 11.300 | ||||||
| 2017-01-13 | 2017-01-11 | 4 | Christianson Gary | CASC | Stock Option (right to buy) | D | 4,64 | 51.200 | 51.200 | |||||
| 2017-01-13 | 2017-01-11 | 4 | EASTLAND JULIA MARIE | CASC | Restricted Share Unit (RSU) | D | 11.300 | 11.300 | ||||||
| 2017-01-13 | 2017-01-11 | 4 | EASTLAND JULIA MARIE | CASC | Stock Option (right to buy) | D | 4,64 | 51.200 | 51.200 | |||||
| 2017-01-13 | 2017-01-11 | 4 | PETERSON SCOTT ROBERT | CASC | Restricted Share Unit (RSU) | D | 11.300 | 11.300 | ||||||
| 2017-01-13 | 2017-01-11 | 4 | PETERSON SCOTT ROBERT | CASC | Stock Option (right to buy) | D | 4,64 | 51.200 | 51.200 | |||||
| 2016-08-18 | 2016-08-17 | 4 | Myers Scott Dunseth | CASC | Common Stock | D | 1,1499 | 45.000 | 52 | 107.500 | ||||
| 2016-06-28 | 2016-06-24 | 4 | HENNEY CHRISTOPHER S | CASC | Restricted Share Units (RSU) | D | 54.347 | 54.347 | ||||||
| 2016-06-28 | 2016-06-24 | 4 | James Steven P | CASC | Restricted Share Unit (RSU) | D | 54.347 | 54.347 | ||||||
| 2016-06-28 | 2016-06-24 | 4 | LOVE TED W | CASC | Restricted Share Unit (RSU) | D | 54.347 | 54.347 | ||||||
| 2016-06-28 | 2016-06-24 | 4 | SPIEGELMAN DANIEL K | CASC | Restricted Share Unit (RSU) | D | 54.347 | 54.347 | ||||||
| 2016-06-28 | 2016-06-28 | 4 | Myers Scott Dunseth | CASC | Common Stock | D | 0,8000 | 62.500 | 50 | 62.500 | ||||
| 2016-06-28 | 2016-06-24 | 4 | Jackson Richard L. | CASC | Restricted Share Unit (RSU) | D | 54.347 | 54.347 | ||||||
| 2016-06-28 | 2016-06-24 | 4 | Fyfe Gwen A. | CASC | Restricted Share Unit (RSU) | D | 54.347 | 54.347 | ||||||
| 2016-06-27 | 2016-06-23 | 4 | LAMPERT MARK N Please see footnote | ONTY | Series D Convertible Preferred Stock | I | 0,80 | 800,0000 | 6.197 | 4.958 | 6.197 | |||
| 2016-06-27 | 2016-06-23 | 4 | LAMPERT MARK N | ONTY | Series D Convertible Preferred Stock | D | 0,80 | 800,0000 | 1.029 | 823 | 1.029 | |||
| 2016-06-27 | 2016-06-23 | 4 | LAMPERT MARK N | ONTY | Series D Convertible Preferred Stock | D | 0,80 | 800,0000 | 4.519 | 3.615 | 4.519 | |||
| 2016-06-27 | 2016-06-23 | 4 | LAMPERT MARK N | ONTY | Series D Convertible Preferred Stock | D | 0,80 | 800,0000 | 5.505 | 4.404 | 5.505 | |||
| 2016-05-19 | 2016-05-17 | 4 | Christianson Gary | ONTY | Stock Option (right to buy) | D | 1,15 | 250.000 | 250.000 | |||||
| 2016-05-19 | 2016-05-17 | 4 | EASTLAND JULIA MARIE | ONTY | Stock Option (right to buy) | D | 1,15 | 300.000 | 300.000 | |||||
| 2016-05-19 | 2016-05-17 | 4 | PETERSON SCOTT ROBERT | ONTY | Stock Option (right to buy) | D | 1,15 | 325.000 | 325.000 | |||||
| 2016-04-06 | 3 | Myers Scott Dunseth | ONTY | No securities beneficially held | D | 0 | ||||||||
| 2016-04-06 | 2016-04-04 | 4 | Myers Scott Dunseth | ONTY | Stock Option (right to buy) | D | 1,18 | 2.848.855 | 2.848.855 | |||||
| 2016-03-16 | 2016-03-16 | 4 | HENNEY CHRISTOPHER S | ONTY | Stock Option (right to buy) | D | 1,06 | 150.000 | 150.000 | |||||
| 2016-01-21 | 3 | Fyfe Gwen A. | ONTY | Common Stock | D | 20.000 | ||||||||
| 2016-01-21 | 3 | Fyfe Gwen A. | ONTY | Common Stock | D | 20.000 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 23.547.788 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 21.842.395 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 23.547.788 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 23.547.788 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 21.842.395 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 19.541.857 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N Please see footnote | ONTY | Common Stock, no par value per share | I | 29.064.800 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 23.547.788 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 21.842.395 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 19.541.857 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N Please see footnote | ONTY | Common Stock, no par value per share | I | 29.064.800 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 23.547.788 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 19.541.857 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 21.842.395 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 19.541.857 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N Please see footnote | ONTY | Common Stock, no par value per share | I | 29.064.800 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 21.842.395 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N Please see footnote | ONTY | Common Stock, no par value per share | I | 29.064.800 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 19.541.857 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N Please see footnote | ONTY | Common Stock, no par value per share | I | 29.064.800 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 21.842.395 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 23.547.788 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 19.541.857 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N Please see footnote | ONTY | Common Stock, no par value per share | I | 29.064.800 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 23.547.788 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 21.842.395 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 19.541.857 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N Please see footnote | ONTY | Common Stock, no par value per share | I | 29.064.800 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 23.547.788 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 21.842.395 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N | ONTY | Common Stock, no par value per share | D | 19.541.857 | ||||||||
| 2015-12-22 | 3 | LAMPERT MARK N Please see footnote | ONTY | Common Stock, no par value per share | I | 29.064.800 | ||||||||
| 2015-09-28 | 2015-09-24 | 4 | PETERSON SCOTT ROBERT | ONTY | Stock Option (right to buy) | D | 3,51 | 250.000 | 250.000 | |||||
| 2015-09-28 | 2015-09-24 | 4 | Jackson Richard L. | ONTY | Restricted Share Unit (RSU) | D | 14.245 | 14.245 | ||||||
| 2015-09-28 | 2015-09-24 | 4 | HAUSMAN DIANA | ONTY | Stock Option (right to buy) | D | 3,51 | 250.000 | 250.000 | |||||
| 2015-09-28 | 2015-09-24 | 4 | LOVE TED W | ONTY | Restricted Share Unit (RSU) | D | 14.245 | 14.245 | ||||||
| 2015-09-28 | 2015-09-24 | 4 | James Steven P | ONTY | Restricted Share Unit (RSU) | D | 14.245 | 14.245 | ||||||
| 2015-09-28 | 2015-09-24 | 4 | HENNEY CHRISTOPHER S | ONTY | Restricted Share Units (RSU) | D | 14.245 | 14.245 | ||||||
| 2015-09-28 | 2015-09-24 | 4 | KIRKMAN ROBERT L | ONTY | Stock Option (right to buy) | D | 3,51 | 750.000 | 750.000 | |||||
| 2015-09-28 | 2015-09-24 | 4 | SPIEGELMAN DANIEL K | ONTY | Restricted Share Unit (RSU) | D | 14.245 | 14.245 | ||||||
| 2015-09-28 | 2015-09-24 | 4 | EASTLAND JULIA MARIE | ONTY | Stock Option (right to buy) | D | 3,51 | 250.000 | 250.000 | |||||
| 2015-09-28 | 2015-09-24 | 4 | Christianson Gary | ONTY | Stock Option (right to buy) | D | 3,51 | 250.000 | 250.000 | |||||
| 2015-09-09 | 2015-09-05 | 4 | LOVE TED W | ONTY | Restricted Share Unit (RSU) | D | -17.341 | 0 | ||||||
| 2015-09-09 | 2015-09-05 | 4 | LOVE TED W | ONTY | Common Stock | D | 3,2500 | -4.336 | -14 | 13.005 | ||||
| 2015-09-09 | 2015-09-05 | 4 | LOVE TED W | ONTY | Common Stock | D | 17.341 | 17.341 | ||||||
| 2015-06-16 | 2015-06-13 | 4 | HENNEY CHRISTOPHER S | ONTY | Restricted Share Unit (RSU) | D | -16.042 | 0 | ||||||
| 2015-06-16 | 2014-06-13 | 4 | HENNEY CHRISTOPHER S | ONTY | Common Stock | D | 3,8800 | -4.011 | -16 | 135.807 | ||||
| 2015-06-16 | 2014-06-13 | 4 | HENNEY CHRISTOPHER S | ONTY | Common Stock | D | 16.042 | 139.818 | ||||||
| 2015-06-16 | 2014-06-12 | 4 | HENNEY CHRISTOPHER S | ONTY | Restricted Share Units (RSU) | D | 12.886 | 12.886 | ||||||
| 2015-06-16 | 2015-06-12 | 4 | James Steven P | ONTY | Restricted Share Unit (RSU) | D | 12.886 | 12.886 | ||||||
| 2015-06-16 | 2015-06-12 | 4 | LOVE TED W | ONTY | Restricted Share Unit (RSU) | D | 12.886 | 12.886 | ||||||
| 2015-06-16 | 2015-06-13 | 4 | SPIEGELMAN DANIEL K | ONTY | Restricted Share Unit (RSU) | D | -16.042 | 0 | ||||||
| 2015-06-16 | 2015-06-13 | 4 | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 3,8800 | -4.011 | -16 | 52.675 | ||||
| 2015-06-16 | 2015-06-13 | 4 | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 16.042 | 56.686 | ||||||
| 2015-06-16 | 2015-06-12 | 4 | SPIEGELMAN DANIEL K | ONTY | Restricted Share Unit (RSU) | D | 12.886 | 12.886 | ||||||
| 2015-06-16 | 2015-06-13 | 4 | Jackson Richard L. | ONTY | Restricted Share Unit (RSU) | D | -16.042 | 0 | ||||||
| 2015-06-16 | 2015-06-13 | 4 | Jackson Richard L. | ONTY | Common Stock | D | 3,8800 | -4.011 | -16 | 59.557 | ||||
| 2015-06-16 | 2015-06-13 | 4 | Jackson Richard L. | ONTY | Common Stock | D | 16.042 | 63.568 | ||||||
| 2015-06-16 | 2015-06-12 | 4 | Jackson Richard L. | ONTY | Restricted Share Unit (RSU) | D | 12.886 | 12.886 | ||||||
| 2015-06-03 | 2015-06-01 | 4 | HAUSMAN DIANA By spouse | ONTY | Common Stock | I | 4,6500 | 5.747 | 27 | 5.747 | ||||
| 2015-04-02 | 2015-03-26 | 4/A | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 1,5856 | 10.000 | 16 | 40.644 | ||||
| 2015-04-02 | 2015-03-25 | 4/A | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 1,6271 | 10.000 | 16 | 30.644 | ||||
| 2015-04-01 | 2015-03-26 | 4 | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 1,5856 | 10.000 | 16 | 40.644 | ||||
| 2015-04-01 | 2015-03-25 | 4 | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 1,6271 | 10.000 | 16 | 30.644 | ||||
| 2015-03-13 | 2015-03-12 | 4 | James Steven P | ONTY | Restricted Share Unit (RSU) | D | 27.932 | 27.932 | ||||||
| 2015-03-03 | 3 | James Steven P | ONTY | No securities are beneficially owned | D | 0 | ||||||||
| 2015-02-09 | 2015-02-05 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund II, L.P. | ONTY | Preferred Stock, $0.0001 per share | I | 1,50 | 1.400 | 1.400 | |||||
| 2015-02-09 | 2015-02-05 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund, L.P. | ONTY | Preferred Stock, $0.0001 per share | I | 1,50 | 2.600 | 2.600 | |||||
| 2015-02-09 | 2015-02-05 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund II, L.P. | ONTY | Common Stock, $0.0001 par value | I | -1.400.000 | 1.898.293 | ||||||
| 2015-02-09 | 2015-02-05 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund, L.P. | ONTY | Common Stock, $0.0001 par value | I | -2.600.000 | 3.762.683 | ||||||
| 2014-12-17 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | ONTY | Common Stock, $0.0001 par value | I | 12.446.194 | ||||||||
| 2014-12-17 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | ONTY | Common Stock, $0.0001 par value | I | 12.446.194 | ||||||||
| 2014-12-17 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | ONTY | Common Stock, $0.0001 par value | I | 15.401.402 | ||||||||
| 2014-12-17 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | ONTY | Common Stock, $0.0001 par value | I | 15.401.402 | ||||||||
| 2014-12-17 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | ONTY | Common Stock, $0.0001 par value | I | 12.446.194 | ||||||||
| 2014-12-17 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | ONTY | Common Stock, $0.0001 par value | I | 15.401.402 | ||||||||
| 2014-12-17 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | ONTY | Common Stock, $0.0001 par value | I | 12.446.194 | ||||||||
| 2014-12-17 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | ONTY | Common Stock, $0.0001 par value | I | 15.401.402 | ||||||||
| 2014-12-17 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | ONTY | Common Stock, $0.0001 par value | I | 12.446.194 | ||||||||
| 2014-12-17 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | ONTY | Common Stock, $0.0001 par value | I | 15.401.402 | ||||||||
| 2014-12-17 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | ONTY | Common Stock, $0.0001 par value | I | 12.446.194 | ||||||||
| 2014-12-17 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | ONTY | Common Stock, $0.0001 par value | I | 15.401.402 | ||||||||
| 2014-12-17 | 2014-12-17 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund II, L.P. | ONTY | Common Stock, $0.0001 par value | I | 1,7331 | 55.197 | 96 | 3.298.293 | ||||
| 2014-12-17 | 2014-12-17 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund, L.P. | ONTY | Common Stock, $0.0001 par value | I | 1,7331 | 98.298 | 170 | 6.362.683 | ||||
| 2014-12-17 | 2014-12-15 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund II, L.P. | ONTY | Common Stock, $0.0001 par value | I | 1,8789 | 79.434 | 149 | 3.243.096 | ||||
| 2014-12-17 | 2014-12-15 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund, L.P. | ONTY | Common Stock, $0.0001 par value | I | 1,8789 | 145.515 | 273 | 6.264.385 | ||||
| 2014-12-16 | 2014-12-16 | 4 | HAUSMAN DIANA | ONTY | Stock Option (right to buy) | D | 1,76 | 150.000 | 150.000 | |||||
| 2014-12-16 | 2014-12-16 | 4 | KIRKMAN ROBERT L | ONTY | Stock Option (right to buy) | D | 1,76 | 300.000 | 300.000 | |||||
| 2014-12-16 | 2014-12-16 | 4 | EASTLAND JULIA MARIE | ONTY | Stock Option (right to buy) | D | 1,76 | 100.000 | 100.000 | |||||
| 2014-12-16 | 2014-12-16 | 4 | PETERSON SCOTT ROBERT | ONTY | Stock Option (right to buy) | D | 1,76 | 150.000 | 150.000 | |||||
| 2014-12-16 | 2014-12-16 | 4 | Venkatesan Jay | ONTY | Stock Option (right to buy) | D | 1,76 | 100.000 | 100.000 | |||||
| 2014-12-16 | 2014-12-16 | 4 | Christianson Gary | ONTY | Stock Option (right to buy) | D | 1,76 | 100.000 | 100.000 | |||||
| 2014-10-08 | 2013-07-10 | 4 | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 1,7201 | -3.403 | -6 | 20.644 | ||||
| 2014-10-08 | 2013-02-20 | 4 | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 1,9604 | -12.780 | -25 | 24.047 | ||||
| 2014-09-26 | 2014-09-23 | 4/A | Venkatesan Jay By Ayer Special Situations Fund I, LP | ONTY | Common Stock | I | 2,0000 | 250.000 | 500 | 250.000 | ||||
| 2014-09-25 | 2014-09-23 | 4 | Venkatesan Jay By Ayer Special Situations Fund I, LP | ONTY | Common Stock | I | 2,0000 | 250.000 | 500 | 250.000 | ||||
| 2014-09-05 | 2014-09-04 | 4 | Venkatesan Jay | ONTY | Stock Option (right to buy) | D | 2,24 | 100.000 | 100.000 | |||||
| 2014-08-12 | 3 | Venkatesan Jay | ONTY | Common Stock | D | 100.000 | ||||||||
| 2014-08-12 | 3 | Venkatesan Jay | ONTY | Common Stock | D | 100.000 | ||||||||
| 2014-08-12 | 2014-08-08 | 4 | Venkatesan Jay By Andaman Orphan Therapies, LLC | ONTY | Common Stock | I | 263.493 | 263.493 | ||||||
| 2014-08-12 | 2014-08-08 | 4 | Venkatesan Jay | ONTY | Common Stock | D | 3.776.723 | 3.826.723 | ||||||
| 2014-07-16 | 2014-07-16 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund II, L.P. | ONTY | Warrants | I | 5,00 | 1,5900 | -242.814 | -386 | 1.223.484 | |||
| 2014-07-16 | 2014-07-16 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund, L.P. | ONTY | Warrants | I | 5,00 | 1,5900 | -407.136 | -647 | 2.288.698 | |||
| 2014-07-16 | 2014-07-16 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund II, L.P. | ONTY | Common Stock, $0.0001 par value | I | 3,2400 | -258.230 | -837 | 2.412.290 | ||||
| 2014-07-16 | 2014-07-16 | 4 | BVF PARTNERS L P/IL By Biotechnology Value Fund, L.P. | ONTY | Common Stock, $0.0001 par value | I | 3,2400 | -296.008 | -959 | 4.512.523 | ||||
| 2014-06-10 | 2014-06-07 | 4 | HENNEY CHRISTOPHER S | ONTY | Common Stock | D | 3,0600 | -2.044 | -6 | 123.776 | ||||
| 2014-06-10 | 2014-06-06 | 4 | HENNEY CHRISTOPHER S | ONTY | Restricted Share Units (RSU) | D | 16.339 | 16.339 | ||||||
| 2014-06-10 | 2014-06-06 | 4 | LOVE TED W | ONTY | Restricted Share Unit (RSU) | D | 16.339 | 16.339 | ||||||
| 2014-06-10 | 2014-06-07 | 4 | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 3,0600 | -2.044 | -6 | 36.827 | ||||
| 2014-06-10 | 2014-06-06 | 4 | SPIEGELMAN DANIEL K | ONTY | Restricted Share Unit (RSU) | D | 16.339 | 16.339 | ||||||
| 2014-06-10 | 2014-06-07 | 4 | STOUGHTON W. VICKERY | ONTY | Common Stock | D | 3,0600 | -2.044 | -6 | 46.692 | ||||
| 2014-06-10 | 2014-06-06 | 4 | STOUGHTON W. VICKERY | ONTY | Restricted Share Unit (RSU) | D | 16.339 | 16.339 | ||||||
| 2014-06-10 | 2014-06-07 | 4 | Jackson Richard L. | ONTY | Common Stock | D | 3,0600 | -2.044 | -6 | 47.526 | ||||
| 2014-06-10 | 2014-06-06 | 4 | Jackson Richard L. | ONTY | Restricted Share Unit (RSU) | D | 16.339 | 16.339 | ||||||
| 2014-03-12 | 2014-03-11 | 4 | HENNEY CHRISTOPHER S | ONTY | Restricted Share Unit (RSU) | D | -19.352 | 0 | ||||||
| 2014-03-12 | 2014-03-11 | 4 | HENNEY CHRISTOPHER S | ONTY | Common Stock | D | 3,6500 | -4.838 | -18 | 125.820 | ||||
| 2014-03-12 | 2014-03-11 | 4 | HENNEY CHRISTOPHER S | ONTY | Common Stock | D | 19.352 | 130.658 | ||||||
| 2014-03-12 | 2014-03-11 | 4 | SPIEGELMAN DANIEL K | ONTY | Restricted Share Unit (RSU) | D | -19.352 | 0 | ||||||
| 2014-03-12 | 2014-03-11 | 4 | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 3,6500 | -4.838 | -18 | 38.871 | ||||
| 2014-03-12 | 2014-03-11 | 4 | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 19.352 | 43.709 | ||||||
| 2014-03-12 | 2014-03-11 | 4 | STOUGHTON W. VICKERY | ONTY | Restricted Share Unit (RSU) | D | -19.352 | 0 | ||||||
| 2014-03-12 | 2014-03-11 | 4 | STOUGHTON W. VICKERY | ONTY | Common Stock | D | 3,6500 | -4.838 | -18 | 48.736 | ||||
| 2014-03-12 | 2014-03-11 | 4 | STOUGHTON W. VICKERY | ONTY | Common Stock | D | 19.352 | 53.574 | ||||||
| 2014-03-12 | 2014-03-11 | 4 | Jackson Richard L. | ONTY | Restricted Share Unit (RSU) | D | -19.352 | 0 | ||||||
| 2014-03-12 | 2014-03-11 | 4 | Jackson Richard L. | ONTY | Common Stock | D | 3,6500 | -4.838 | -18 | 49.570 | ||||
| 2014-03-12 | 2014-03-11 | 4 | Jackson Richard L. | ONTY | Common Stock | D | 19.352 | 54.408 | ||||||
| 2013-12-16 | 2013-12-12 | 4 | KIRKMAN ROBERT L | ONTY | Stock Option (right to buy) | D | 1,74 | 600.000 | 600.000 | |||||
| 2013-12-16 | 2013-12-12 | 4 | Christianson Gary | ONTY | Stock Option (right to buy) | D | 1,74 | 150.000 | 150.000 | |||||
| 2013-12-16 | 2013-12-12 | 4 | EASTLAND JULIA MARIE | ONTY | Stock Option (right to buy) | D | 1,74 | 150.000 | 150.000 | |||||
| 2013-12-16 | 2013-12-12 | 4 | PETERSON SCOTT ROBERT | ONTY | Stock Option (right to buy) | D | 1,74 | 150.000 | 150.000 | |||||
| 2013-12-16 | 2013-12-12 | 4 | HAUSMAN DIANA | ONTY | Stock Option (right to buy) | D | 1,74 | 150.000 | 150.000 | |||||
| 2013-11-05 | 2013-11-01 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | ONTY | Common Stock | I | 1,7800 | 79.360 | 141 | 2.670.520 | ||||
| 2013-11-05 | 2013-11-01 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | ONTY | Common Stock | I | 1,7800 | 49.640 | 88 | 4.808.531 | ||||
| 2013-09-06 | 3 | LOVE TED W | ONTY | Common Stock | D | 0 | ||||||||
| 2013-09-06 | 2013-09-05 | 4 | LOVE TED W | ONTY | Restricted Share Unit (RSU) | D | 17.341 | 17.341 | ||||||
| 2013-08-12 | 2013-08-08 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | ONTY | Common Stock | I | 1,6495 | 177.940 | 294 | 2.591.160 | ||||
| 2013-08-12 | 2013-08-08 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | ONTY | Common Stock | I | 1,6495 | 80.421 | 133 | 4.758.891 | ||||
| 2013-08-02 | 2013-08-01 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | ONTY | Common Stock | I | 1,7828 | 35.703 | 64 | 2.413.220 | ||||
| 2013-08-02 | 2013-08-01 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | ONTY | Common Stock | I | 1,7828 | 122.641 | 219 | 4.678.470 | ||||
| 2013-08-02 | 2013-07-31 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | ONTY | Common Stock | I | 1,7097 | 179.743 | 307 | 4.555.829 | ||||
| 2013-06-14 | 2013-06-13 | 4 | HENNEY CHRISTOPHER S | ONTY | Restricted Share Units (RSU) | D | 16.042 | 16.042 | ||||||
| 2013-06-14 | 2013-06-13 | 4 | SPIEGELMAN DANIEL K | ONTY | Restricted Share Unit (RSU) | D | 16.042 | 16.042 | ||||||
| 2013-06-14 | 2013-06-13 | 4 | STOUGHTON W. VICKERY | ONTY | Restricted Share Unit (RSU) | D | 16.042 | 16.042 | ||||||
| 2013-06-14 | 2013-06-13 | 4 | WILLIAMS DOUGLAS E | ONTY | Restricted Share Unit (RSU) | D | 16.042 | 16.042 | ||||||
| 2013-06-14 | 2013-06-13 | 4 | Jackson Richard L. | ONTY | Restricted Share Unit (RSU) | D | 16.042 | 16.042 | ||||||
| 2013-06-11 | 2013-06-09 | 4 | HENNEY CHRISTOPHER S | ONTY | Common Stock | D | 1,8600 | -1.135 | -2 | 111.306 | ||||
| 2013-06-11 | 2013-06-09 | 4 | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 1,8600 | -1.135 | -2 | 24.357 | ||||
| 2013-06-11 | 2013-06-09 | 4 | STOUGHTON W. VICKERY | ONTY | Common Stock | D | 1,8600 | -1.135 | -2 | 34.222 | ||||
| 2013-06-11 | 2013-06-09 | 4 | WILLIAMS DOUGLAS E | ONTY | Common Stock | D | 1,8600 | -1.135 | -2 | 19.961 | ||||
| 2013-06-11 | 2013-06-09 | 4 | Jackson Richard L. | ONTY | Common Stock | D | 1,8600 | -1.135 | -2 | 35.056 | ||||
| 2013-06-07 | 3 | LAMPERT MARK N By Investment 10, L.L.C. | ONTY | Common Stock, $0.0001 par value | I | 1.298.842 | ||||||||
| 2013-06-07 | 3 | LAMPERT MARK N By Biotechnology Value Fund II, L.P. | ONTY | Common Stock, $0.0001 par value | I | 2.303.607 | ||||||||
| 2013-06-07 | 3 | LAMPERT MARK N By Biotechnology Value Fund, L.P. | ONTY | Common Stock, $0.0001 par value | I | 4.235.529 | ||||||||
| 2013-06-07 | 2013-06-07 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | ONTY | Common Stock | I | 1,8304 | 41.526 | 76 | 2.377.517 | ||||
| 2013-06-07 | 2013-06-07 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | ONTY | Common Stock | I | 1,8304 | 74.726 | 137 | 4.376.086 | ||||
| 2013-06-07 | 2013-06-06 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | ONTY | Common Stock | I | 1,7809 | 27.384 | 49 | 2.335.991 | ||||
| 2013-06-07 | 2013-06-06 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | ONTY | Common Stock | I | 1,7809 | 55.531 | 99 | 4.301.360 | ||||
| 2013-06-07 | 2013-06-05 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | ONTY | Common Stock | I | 1,7500 | 5.000 | 9 | 2.308.607 | ||||
| 2013-06-07 | 2013-06-05 | 4 | BVF PARTNERS L P/IL See Explanation of Responses | ONTY | Common Stock | I | 1,7500 | 10.300 | 18 | 4.245.829 | ||||
| 2012-12-14 | 3/A | PETERSON SCOTT ROBERT | ONTY | Common Stock | D | 10.424 | ||||||||
| 2012-12-14 | 2012-12-12 | 4 | KIRKMAN ROBERT L | ONTY | Stock Option (right to buy) | D | 4,74 | 100.000 | 100.000 | |||||
| 2012-12-14 | 2012-12-12 | 4 | Christianson Gary | ONTY | Stock Option (right to buy) | D | 4,74 | 50.000 | 50.000 | |||||
| 2012-12-14 | 2012-12-12 | 4 | EASTLAND JULIA MARIE | ONTY | Stock Option (right to buy) | D | 4,74 | 50.000 | 50.000 | |||||
| 2012-12-14 | 2012-12-12 | 4 | PETERSON SCOTT ROBERT | ONTY | Stock Option (right to buy) | D | 4,74 | 50.000 | 50.000 | |||||
| 2012-12-14 | 2012-12-12 | 4 | HAUSMAN DIANA | ONTY | Stock Option (right to buy) | D | 4,74 | 50.000 | 50.000 | |||||
| 2012-12-11 | 3 | PETERSON SCOTT ROBERT | ONTY | Common Stock | D | 10.424 | ||||||||
| 2012-12-11 | 3 | HAUSMAN DIANA | ONTY | Common Stock | D | 0 | ||||||||
| 2012-06-08 | 2012-06-07 | 4 | STOUGHTON W. VICKERY | ONTY | Common Stock | D | 3,6700 | 8.174 | 30 | 35.357 | ||||
| 2012-06-08 | 2012-06-07 | 4 | WILLIAMS DOUGLAS E | ONTY | Common Stock | D | 3,6700 | 8.174 | 30 | 21.096 | ||||
| 2012-06-08 | 2012-06-07 | 4 | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 3,6700 | 8.174 | 30 | 25.492 | ||||
| 2012-06-08 | 2012-06-07 | 4 | HENNEY CHRISTOPHER S | ONTY | Common Stock | D | 3,6700 | 8.174 | 30 | 112.441 | ||||
| 2012-06-08 | 2012-06-07 | 4 | Jackson Richard L. | ONTY | Common Stock | D | 3,6700 | 8.174 | 30 | 36.191 | ||||
| 2012-06-05 | 2012-06-03 | 4 | WILLIAMS DOUGLAS E | ONTY | Common Stock | D | 3,5100 | -2.021 | -7 | 12.922 | ||||
| 2012-06-05 | 2012-03-16 | 4 | WILLIAMS DOUGLAS E | ONTY | Common Stock | D | -2.320 | 14.943 | ||||||
| 2012-06-05 | 2012-06-03 | 4 | STOUGHTON W. VICKERY | ONTY | Common Stock | D | 3,5100 | -2.021 | -7 | 27.183 | ||||
| 2012-06-05 | 2012-06-03 | 4 | HENNEY CHRISTOPHER S | ONTY | Common Stock | D | 3,5100 | -2.021 | -7 | 104.267 | ||||
| 2012-06-05 | 2012-06-03 | 4 | SPIEGELMAN DANIEL K | ONTY | Common Stock | D | 3,5100 | -2.021 | -7 | 17.318 | ||||
| 2012-06-05 | 2012-06-03 | 4 | Jackson Richard L. | ONTY | Common Stock | D | 3,5100 | -2.021 | -7 | 28.017 | ||||
| 2012-05-04 | 2012-05-03 | 4 | HENNEY CHRISTOPHER S | ONTY | Restricted Share Units | D | -989 | 0 | ||||||
| 2012-05-04 | 2012-05-03 | 4 | HENNEY CHRISTOPHER S | ONTY | Common Stock | D | 4,1500 | -247 | -1 | 106.288 | ||||
| 2012-05-04 | 2012-05-03 | 4 | HENNEY CHRISTOPHER S | ONTY | Common Stock | D | 989 | 106.535 | ||||||
| 2012-05-04 | 2012-05-03 | 4 | STOUGHTON W. VICKERY | ONTY | Restricted Share Units | D | -989 | 0 | ||||||
| 2012-05-04 | 2012-05-03 | 4 | STOUGHTON W. VICKERY | ONTY | Common Stock | D | 4,1500 | -247 | -1 | 29.204 | ||||
| 2012-05-04 | 2012-05-03 | 4 | STOUGHTON W. VICKERY | ONTY | Common Stock | D | 989 | 29.451 | ||||||
| 2012-05-04 | 2012-05-03 | 4 | Jackson Richard L. | ONTY | Restricted Share Units | D | -989 | 0 | ||||||
| 2012-05-04 | 2012-05-03 | 4 | Jackson Richard L. | ONTY | Common Stock | D | 4,1500 | -247 | -1 | 30.038 | ||||
| 2012-05-04 | 2012-05-03 | 4 | Jackson Richard L. | ONTY | Common Stock | D | 989 | 30.285 | ||||||
| 2012-01-03 | 2011-12-31 | 4 | STOUGHTON W. VICKERY | ONTY | Restricted Share Units | D | -2.388 | 0 | ||||||
| 2012-01-03 | 2011-12-31 | 4 | STOUGHTON W. VICKERY | ONTY | Common Stock | D | 7,5800 | -597 | -5 | 28.462 | ||||
| 2012-01-03 | 2011-12-31 | 4 | STOUGHTON W. VICKERY | ONTY | Common Stock | D | 2.388 | 29.059 | ||||||
| 2012-01-03 | 2011-12-31 | 4 | HENNEY CHRISTOPHER S | ONTY | Restricted Share Units | D | -2.388 | 0 | ||||||
| 2012-01-03 | 2011-12-31 | 4 | HENNEY CHRISTOPHER S | ONTY | Common Stock | D | 7,5800 | -597 | -5 | 105.546 | ||||
| 2012-01-03 | 2011-12-31 | 4 | HENNEY CHRISTOPHER S | ONTY | Common Stock | D | 2.388 | 106.143 | ||||||
| 2012-01-03 | 2011-12-31 | 4 | Jackson Richard L. | ONTY | Restricted Share Units | D | -2.388 | 0 | ||||||
| 2012-01-03 | 2011-12-31 | 4 | Jackson Richard L. | ONTY | Common Stock | D | 7,5800 | -597 | -5 | 29.296 | ||||
| 2012-01-03 | 2011-12-31 | 4 | Jackson Richard L. | ONTY | Common Stock | D | 2.388 | 29.893 | ||||||
| 2009-10-06 | 3 | WILLIAMS DOUGLAS E | ONTY | No securities are beneficially owned | D | 0 |
P
Åbent marked eller privat køb af ikke-afledte eller afledte værdipapirer
S
Åbent marked eller privat salg af ikke-afledte eller afledte værdipapirer
A
Tildeling, tildeling eller anden erhvervelse af værdipapirer fra virksomheden (såsom en option)
C
Konvertering af derivat
D
Salg eller overførsel af værdipapirer tilbage til virksomheden
F
Betaling af udnyttelseskurs eller skatteforpligtelse ved brug af en del af værdipapirer modtaget fra selskabet
G
Gave af værdipapirer af eller til insideren
K
Aktieswaps og lignende sikringstransaktioner
M
Udnyttelse eller konvertering af afledt værdipapir modtaget fra virksomheden (såsom en option)
V
En transaktion rapporteret frivilligt på formular 4
J
Andet (ledsaget af en fodnote, der beskriver transaktionen)
