ADHD / Alcobra Ltd. - SEC-arkivering, Årsberetning, Fuldmagtserklæring

Alcobra Ltd.
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SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to Alcobra Ltd.
SEC Filings (Chronological Order)
Denne side giver en komplet, kronologisk liste over SEC-arkiveringer, eksklusive ejerskabsregistreringer, som vi leverer andre steder.
February 14, 2020 SC 13G/A

03969T109 / ARCTURUS THERAPEUTICS HOLDIN / ARK Investment Management LLC - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.

August 16, 2019 CORRESP

ARCT / Arcturus Therapeutics Ltd. CORRESP - -

CORRESP Jeffrey A. Baumel Partner [email protected] D +1 973 912 7189 Dentons US LLP 1221 Avenue of the Americas New York, NY 10020-1089 USA August 16, 2019 VIA EDGAR Division of Corporation Finance Office of Healthcare & Insurance Securities and Exchange Commission 100 F Street, NE Washington, DC 20549-1090 Attention: Andi Carpenter Re: Arcturus Therapeutics Ltd. Form 10-K for the Fiscal

August 1, 2019 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 1, 2019 ARCTURUS THERAPEUTICS HOLDINGS INC. (Exact name of registrant as specified in its charter) Delaware 001-38942 32-0595345 (State or other jurisdiction of incorporation)

August 1, 2019 EX-99.1

Arcturus Therapeutics Receives up to $15 Million Commitment from the Cystic Fibrosis Foundation to Create mRNA Therapies to Treat Cystic Fibrosis Patients

EX-99.1 2 e618580ex99-1.htm Arcturus Therapeutics Receives up to $15 Million Commitment from the Cystic Fibrosis Foundation to Create mRNA Therapies to Treat Cystic Fibrosis Patients San Diego, Calif, August 1, 2019 - Arcturus Therapeutics (“Arcturus” or the “Company”), a leading RNA medicines company, today announced that the Cystic Fibrosis Foundation (CF Foundation), has increased its commitmen

June 21, 2019 EX-4.7

2019 Omnibus Equity Incentive Plan

EX-4.7 Exhibit 4.7 ARCTURUS THERAPEUTICS HOLDINGS INC. 2019 OMNIBUS EQUITY INCENTIVE PLAN (Effective June 10, 2019) TABLE OF CONTENTS PAGE Article 1. Effective Date, Objectives and Duration 1 1.1 Effective Date of the Plan 1 1.2 Objectives of the Plan 1 1.3 Duration of the Plan 1 Article 2. Definitions 1 2.1 “Affiliate” 1 2.2 “Award” 1 2.3 “Award Agreement” 2 2.4 “Board” 2 2.5 “Bonus Shares” 2 2.6

June 21, 2019 S-8

ARCT / Arcturus Therapeutics Ltd. S-8 - - S-8

S-8 As filed with the Securities and Exchange Commission on June 21, 2019 Registration No.

June 20, 2019 8-K

Regulation FD Disclosure, Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Entry into a Material Definitive Agreement, Unregistered Sales of Equity Securities, Financial Statements and Exhibits

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 18, 2019 ARCTURUS THERAPEUTICS HOLDINGS INC. (Exact name of registrant as specified in its charter) Delaware 001-38942 32-0595345 (State or other jurisdiction of incorporatio

June 20, 2019 EX-99.1

Ultragenyx and Arcturus Therapeutics Expand Existing Research Collaboration and License Agreement to Develop Additional Nucleic Acid Therapies for Rare Diseases

EX-99.1 5 d721252dex991.htm EX-99.1 Exhibit 99.1 Ultragenyx and Arcturus Therapeutics Expand Existing Research Collaboration and License Agreement to Develop Additional Nucleic Acid Therapies for Rare Diseases • Scope of the collaboration expands to include up to 12 rare disease targets and includes Arcturus nucleic acid technologies to enable mRNA, DNA, and siRNA therapeutics • $30 million of upf

June 20, 2019 EX-10.1

Equity Purchase Agreement, dated as of June 18, 2019 (incorporated by reference to the Company’s Current Report on Form 8-K filed on June 20, 2019)

EX-10.1 Exhibit 10.1 EQUITY PURCHASE AGREEMENT THIS EQUITY PURCHASE AGREEMENT (this “Agreement”) is made as of June 18, 2019, by and among Ultragenyx Pharmaceutical Inc., a Delaware corporation (the “Investor”), Arcturus Therapeutics Ltd., an Israeli incorporated company (“Arcturus-Israel”), and Arcturus Therapeutics Holdings Inc., a newly incorporated Delaware corporation (“Arcturus-Delaware”). W

June 20, 2019 EX-10.2

Third Amendment, dated June 18, 2019 to Research Collaboration and License Agreement, dated October 26, 2015, as amended on October 17, 2017 and April 20, 2018, between the Company and Ultragenyx Pharmaceutical Inc.

EX-10.2 Exhibit 10.2 ***Text Omitted and Filed Separately with the Securities and Exchange Commission. Confidential Treatment Requested Under 17 C.F.R. Sections 200.80(b)(4) and Rule 24b-2 THIRD AMENDMENT TO RESEARCH COLLABORATION AND LICENSE AGREEMENT This THIRD AMENDMENT TO RESEARCH COLLABORATION AND LICENSE AGREEMENT (the “Third Amendment”) is effective as of June 18, 2019 (“Third Amendment Eff

June 20, 2019 EX-4.1

Registration Rights Agreement, dated June 18, 2019, between the Company and Ultragenyx Pharmaceutical Inc.

EX-4.1 Exhibit 4.1 CONFIDENTIAL REGISTRATION RIGHTS AGREEMENT by and between ARCTURUS THERAPEUTICS HOLDINGS INC. and ULTRAGENYX PHARMACEUTICAL INC. Dated as of June 18, 2019 REGISTRATION RIGHTS AGREEMENT THIS REGISTRATION RIGHTS AGREEMENT (this “Agreement”), dated as of June 18, 2019, is by and between Arcturus Therapeutics Holdings Inc., a Delaware corporation (the “Company”), and Ultragenyx Phar

May 20, 2019 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of report (Date of earliest event reported): May 20, 2019 ARCTURUS THERAPEUTICS LTD.

May 13, 2019 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of report (Date of earliest event reported): May 13, 2019 ARCTURUS THERAPEUTICS LTD.

May 13, 2019 EX-99.1

Arcturus Therapeutics Announces First Quarter Financial Results and Provides a Corporate Update

EX-99.1 2 arct-ex9916.htm EX-99.1 Exhibit 99.1 Arcturus Therapeutics Announces First Quarter Financial Results and Provides a Corporate Update San Diego, Calif, May 13, 2019 – Arcturus Therapeutics Ltd. (NASDAQ: ARCT), a leading messenger RNA medicines company focused on the discovery, development and commercialization of therapeutics for rare diseases, today reported its financial results for the

May 13, 2019 10-Q

ARCT / Arcturus Therapeutics Ltd. 10-Q Quarterly Report 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2019 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 001-35932 ARCTURUS THERAPEUTICS LTD.

April 12, 2019 424B3

PROXY STATEMENT OF ARCTURUS THERAPEUTICS LTD. PROSPECTUS OF ARCTURUS THERAPEUTICS HOLDINGS INC.

424B3 Table of Contents Filed Pursuant to Rule 424(b)(3) Registration No.: 333-230353 PROXY STATEMENT OF ARCTURUS THERAPEUTICS LTD. PROSPECTUS OF ARCTURUS THERAPEUTICS HOLDINGS INC. Dear Shareholders of Arcturus Therapeutics Ltd.: We are making this proxy statement/prospectus available in connection with the solicitation by the board of directors of Arcturus Therapeutics Ltd. (“Arcturus-Israel” or

April 11, 2019 S-4/A

ARCT / Arcturus Therapeutics Ltd. S-4/A

S-4/A Table of Contents As filed with the Securities and Exchange Commission on April 11, 2019 Registration No.

April 11, 2019 CORRESP

ARCT / Arcturus Therapeutics Ltd. CORRESP - -

CORRESP ARCTURUS THERAPEUTICS LTD. ARCTURUS THERAPEUTICS HOLDINGS, INC. 10628 SCIENCE CENTER DRIVE, SUITE 250 SAN DIEGO, CA 92121 April 11, 2019 U.S. Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, D.C. 20549 Re: Arcturus Therapeutics Ltd. Arcturus Therapeutics Holdings, Inc. Registration Statement on Form S-4 File No. 333-230353 Ladies and Gentlem

April 10, 2019 EX-10.14

Amended and Restated Joint Venture, Research Collaboration and License Agreement, dated as of July 14, 2018 by and between Arcturus Therapeutics, Inc. and Providence Therapeutics, Inc.

EX-10.14 2 arct-ex10146.htm EX-10.14 EXHIBIT 10.14 AMENDED AND RESTATED Joint venture, research COLLABORATION AND LICENSE AGREEMENT This Amended and Restated Joint Venture, Research Collaboration And License Agreement (this “Agreement”) is entered into as of July , 2018 (the “Restatement Date”), by and between Providence Therapeutics Inc., a corporation incorporated under the laws of Alberta, Cana

April 10, 2019 10-K/A

ARCT / Arcturus Therapeutics Ltd. 10-K/A (Annual Report)

10-K/A 1 arct-10ka20181231.htm 10-K/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K/A (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2018 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commissi

March 18, 2019 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

8-K 1 arct-8k20190318.htm ARCT 8-K - Q4 2018 PR UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of report (Date of earliest event reported): March 18, 2019 ARCTURUS THERAPEUTICS LTD. (Exact Name of Registrant as Specified in Charter) State of Israel (State or Other Jurisdiction

March 18, 2019 EX-99.1

Arcturus Therapeutics Provides Corporate Update and Reports Fourth Quarter and Year End 2018 Financial Results

Exhibit 99.1 Arcturus Therapeutics Provides Corporate Update and Reports Fourth Quarter and Year End 2018 Financial Results San Diego, Calif, March 18, 2019 – Arcturus Therapeutics Ltd. (NASDAQ: ARCT), a leading messenger RNA medicines company focused on the discovery, development and commercialization of therapeutics towards rare diseases, today reported its financial results for the quarter and

March 18, 2019 EX-10.15

Research and Collaboration Agreement, dated as of March 8, 2019 by and between Arcturus Therapeutics Inc. and Millennium Pharmaceuticals, Inc., a wholly-owned subsidiary of Takeda Pharmaceutical Company Limited. Incorporated by reference to Exhibit 10.15 to Form 10-K filed on March 15, 2019 (File No. 001-35932)

EX-10.15 4 arct-ex1015582.htm EX-10.15 Exhibit 10.15 ***Text Omitted and Filed Separately with the Securities and Exchange Commission. Confidential Treatment Requested Under 17 C.F.R. Sections 200.80(b)(4) and Rule 24b-2 RESEARCH COLLABORATION AGREEMENT This Research Collaboration Agreement is entered into and effective as of March 8, 2019 (the “Effective Date”), by and between Arcturus Therapeuti

March 18, 2019 EX-10.14

Amended and Restated Joint Venture, Research Collaboration and License Agreement, dated as of July 4, 2018 by and between Arcturus Therapeutics Inc. and Providence Therapeutics, Inc. Incorporated by reference to Exhibit 10.14 to Form 10-K filed on March 15, 2019 (File No. 001-35932)

Exhibit 10.14 ***Text Omitted and Filed Separately with the Securities and Exchange Commission. Confidential Treatment Requested Under 17 C.F.R. Sections 200.80(b)(4) and Rule 24b-2 AMENDED AND RESTATED Joint venture, research COLLABORATION AND LICENSE AGREEMENT This Amended and Restated Joint Venture, Research Collaboration And License Agreement (this “Agreement”) is entered into as of July , 201

March 18, 2019 EX-14.1

Code of Business Conduct and Ethics. Incorporated by reference to Exhibit 14.1 to Form 10-K filed on March 15, 2019 (File No. 001-35932)

Exhibit 14.1 Code of Business Conduct and Ethics Introduction Ethics are important to Arcturus Therapeutics Ltd. (together with its subsidiaries, “Arcturus”) and its directors, officers and employees (each an “Associate”). Arcturus is committed to the highest ethical standards and to conducting its business with the highest level of integrity. The Arcturus Code of Business Conduct and Ethics (the

March 18, 2019 EX-10.13

Share Exchange Agreement, dated as of February 11, 2019, by and between Arcturus Therapeutics Ltd. and Arcturus Therapeutics Holdings Inc. Incorporated by reference to Exhibit 10.13 to Form 10-K filed on March 15, 2019 (File No. 001-35932)

Exhibit 10.13 AGREEMENT drawn up and signed on February 8, 2019 between: ARCTURUS THERAPEUTICS LTD. Company number 514098995 of 58 Harakevet Street Tel-Aviv, Israel (the “Israeli Company”) of the first part; and: ARCTURUS THERAPEUTICS HOLDINGS INC. of 251 Little Falls Drive New Castle County The State of Delaware, 19808 United States (the “New Company”) of the second part; Whereas the Israeli Comp

March 18, 2019 10-K

ARCT / Arcturus Therapeutics Ltd. 10-K (Annual Report)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K (Mark One) ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2018 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number 001-35932 ARCTURUS THERAP

March 16, 2019 S-4

Certificate of Incorporation of the Registrant (incorporated by reference to Annex B to the proxy statement / prospectus which forms part of the Registration Statement on Form S-4 (File No. 333-230353) filed on March 18, 2019).

S-4 Table of Contents As filed with the Securities and Exchange Commission on March 18, 2019 Registration No.

February 27, 2019 EX-99.1

Presentation of Arcturus Therapeutics Ltd., dated February 2019

February 27, 2019 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of report (Date of earliest event reported): February 27, 2019 ARCTURUS THERAPEUTICS LTD.

February 20, 2019 SC 13G/A

ARCT / Arcturus Therapeutics Ltd. / Brosh Capital L.P. - AMENDMENT NO. 1 TO THE SCHEDULE 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b) (Amendment No. 1)1 Arcturus Therapeutics Ltd (Name of Issuer) Ordinary Shares, par value of NIS 0.07 (Title of Class of Securities) M1492T105 (CUSIP Number)

February 14, 2019 SC 13G

ARCT / Arcturus Therapeutics Ltd. / ARK Investment Management LLC - SC 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.

February 11, 2019 EX-99.2

Arcturus Therapeutics Reassumes Full Worldwide Rights to ARCT-810, a Clinical Development Candidate for Ornithine Transcarbamylase (OTC) Deficiency

EX-99.2 3 e618214ex99-2.htm Exhibit 99.2 Arcturus Therapeutics Reassumes Full Worldwide Rights to ARCT-810, a Clinical Development Candidate for Ornithine Transcarbamylase (OTC) Deficiency San Diego, CA – Feb. 11, 2019 – Arcturus Therapeutics Ltd. (NASDAQ: ARCT), a leading RNA medicines company focused on the discovery, development and commercialization of therapeutics towards rare diseases, today

February 11, 2019 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 Date of report (Date of earliest event reported): February 8, 2019 ARCTURUS THERAPEUTICS LTD.

February 11, 2019 EX-99.1

Presentation of Arcturus Therapeutics Ltd., dated February 11, 2019

January 25, 2019 SC 13G/A

ARCT / Arcturus Therapeutics Ltd. / FRANKLIN RESOURCES INC Passive Investment

arct18a3.htm - Generated by SEC Publisher for SEC Filing CUSIP NO. M2239P109 13G Page 1 of 12 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 3)* ARCTURUS THERAPEUTICS LTD. (Name of Issuer) Ordinary Shares, par value of NIS 0.07 (Title of Class of Securities) M2239P109 (CUSIP Number) December 31, 2018 (Da

November 20, 2018 SC 13D/A

ARCT / Arcturus Therapeutics Ltd. / Payne Joseph E Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) (Amendment No. 9)* Arcturus Therapeutics Ltd. (Name of Issuer) Ordinary Shares, par value of NIS 0.07 (Title of Class of Securities) M1492T105 (CUSIP Number) Jeffrey Baum

November 7, 2018 6-K

ADHD / Alcobra Ltd. FORM 6-K (Current Report of Foreign Issuer)

6-K 1 arct6k.htm FORM 6-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO SECTION 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of November, 2018 Commission File Number: 001-35932 ARCTURUS THERAPEUTICS LTD. (Exact Name of Registrant as Specified in Its Charter) 10628 Science Center Drive, Suite

November 7, 2018 EX-99

ARCTURUS THERAPEUTICS LTD. AND ITS SUBSIDIARIES MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS

Exhibit 99.2 ARCTURUS THERAPEUTICS LTD. AND ITS SUBSIDIARIES MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS The following is a discussion of the financial condition and results of operations of Arcturus Therapeutics Ltd. for the three and nine-month periods ended September 30, 2018. Unless otherwise specified herein, references to the “Company,” “we,” “us” or

November 7, 2018 EX-99

ARCTURUS THERAPEUTICS LTD. AND ITS SUBSIDIARIES TABLE OF CONTENTS

EX-99 2 arctex991.htm EX-99.1 Exhibit 99.1 ARCTURUS THERAPEUTICS LTD. AND ITS SUBSIDIARIES TABLE OF CONTENTS Page Financial Statements 1 Condensed Consolidated Balance Sheets as of September 30, 2018 (Unaudited) and December 31, 2017 1 Condensed Consolidated Statements of Operations and Comprehensive Loss for the three and nine months ended September 30, 2018 and 2017 (Unaudited) 2 Condensed Conso

November 7, 2018 EX-99

ARCTURUS THERAPEUTICS Ltd. AND ITS SUBSIDIARIES CONDENSED CONSOLIDATED BALANCE SHEETS (U.S. dollars in thousands)

Exhibit 99.3 Arcturus Therapeutics Provides Corporate Update and Reports Third Quarter 2018 Financial Results San Diego, Calif, November 7, 2018 (GLOBE NEWSWIRE) – Arcturus Therapeutics Ltd. (NASDAQ: ARCT), a leading RNA medicines company focused on the development and commercialization of therapeutics towards rare, infectious, fibrotic, and respiratory diseases with significant unmet medical need

October 15, 2018 S-8

ADHD / Alcobra Ltd. S-8

As filed with the Securities and Exchange Commission on October 15, 2018 Registration No.

October 15, 2018 EX-10.2

Sales Agreement, dated October 15, 2018, by and between Arcturus Therapeutics Ltd. and Leerink Partners LLC. Incorporated by reference to Exhibit 10.2 to the Company’s Report of Foreign Private Issuer on Form 6-K filed on October 15, 2018 (File No. 001-35932).

Exhibit 10.2 Arcturus Therapeutics Ltd. Ordinary Shares (NIS 0.07 par value) SALES AGREEMENT October 15, 2018 LEERINK PARTNERS LLC 1301 Avenue of the Americas, 12th New York, New York 10019 Ladies and Gentlemen: Arcturus Therapeutics Ltd., an Israeli company (the “Company”), confirms its agreement (this “Agreement”) with Leerink Partners LLC (the “Agent”), as follows: 1.Issuance and Sale of Shares

October 15, 2018 EX-10.1

Loan and Security Agreement, dated October 12, 2018, by and between Western Alliance Bank and Arcturus Therapeutics, Inc. Incorporated by reference to Exhibit 10.1 to the Company’s Report of Foreign Private Issuer on Form 6-K filed on October 15, 2018 (File No. 001-35932).

EXHIBIT 10.1 ***Text Omitted and Filed Separately with the Securities and Exchange Commission. Confidential Treatment Requested Under 17 C.F.R. Sections 200.80(b)(4) and Rule 24b-2 ARCTURUS THERAPEUTICS, INC., a DELAWARE CORPORATION WESTERN ALLIANCE BANK, an arizona corporation LOAN AND SECURITY AGREEMENT This LOAN AND SECURITY AGREEMENT (this “Agreement”) is entered into as of October 12, 2018 by

October 15, 2018 6-K

ADHD / Alcobra Ltd. ARCT 6-K 2018-10-15 (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO SECTION 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of October, 2018 (Report No. 2) Commission File Number: 001-35932 ARCTURUS THERAPEUTICS LTD. (Exact Name of Registrant as Specified in Its Charter) 10628 Science Center Drive, Suite 250 San Die

October 15, 2018 424B5

Up to $30,000,000

Filed Pursuant to Rule 424(b)(5) Registration No. 333-209960 PROSPECTUS SUPPLEMENT (To Prospectus dated March 1, 2016) Up to $30,000,000 Ordinary Shares We have entered into a sales agreement, or the Sales Agreement, with Leerink Partners LLC, or Leerink, dated October 15, 2018, relating to our ordinary shares, par value NIS 0.07 per share, offered by this prospectus supplement and the accompanyin

October 1, 2018 EX-99.1

ARCTURUS THERAPEUTICS Ltd. AND ITS SUBSIDIARIES CONDENSED CONSOLIDATED BALANCE SHEETS (U.S. dollars in thousands)

Exhibit 99.1 Arcturus Therapeutics Reports Second Quarter 2018 Financial Results and Provides Corporate Update San Diego, Calif, October 1, 2018 (GLOBE NEWSWIRE) – Arcturus Therapeutics Ltd. (NASDAQ: ARCT), a leading RNA medicines company focused on the development and commercialization of therapeutics towards rare, infectious, fibrotic, and respiratory diseases with significant unmet medical need

October 1, 2018 6-K

ADHD / Alcobra Ltd. 6-K (Current Report of Foreign Issuer)

6-K 1 arct-6k20181001.htm 6-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of October, 2018 Commission File No. 001-35932 ARCTURUS THERAPEUTICS LTD. (Translation of registrant’s name into English) 10628 Science Center Drive, Suite 250 San Di

October 1, 2018 EX-99.2

RESTATED AMENDMENT TO DEVELOPMENT AND OPTION AGREEMENT

EX-99.2 3 arct-ex9926.htm EX-99.2 EXHIBIT 99.2 ***Text Omitted and Filed Separately with the Securities and Exchange Commission. Confidential Treatment Requested Under 17 C.F.R. Sections 200.80(b)(4) and Rule 24b-2 RESTATED AMENDMENT TO DEVELOPMENT AND OPTION AGREEMENT THIS RESTATED AMENDMENT TO DEVELOPMENT AND OPTION AGREEMENT (this “Amendment”), dated as of September 28, 2018 (the “Amendment Res

September 28, 2018 EX-99

ARCTURUS THERAPEUTICS LTD. AND ITS SUBSIDIARIES MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS

EX-99 3 arct-ex992.htm EX-99.2 Exhibit 99.2 ARCTURUS THERAPEUTICS LTD. AND ITS SUBSIDIARIES MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS The following is a discussion of the financial condition and results of operations of Arcturus Therapeutics Ltd. for the three and six-month periods ended June 30, 2018. Unless otherwise specified herein, references to the

September 28, 2018 EX-99

ARCTURUS THERAPEUTICS LTD. AND ITS SUBSIDIARIES TABLE OF CONTENTS

EX-99 2 arct-ex991.htm EX-99.1 Exhibit 99.1 ARCTURUS THERAPEUTICS LTD. AND ITS SUBSIDIARIES TABLE OF CONTENTS Page Financial Statements 1 Condensed Consolidated Balance Sheets as of June 30, 2018 (Unaudited) and December 31, 2017 1 Condensed Consolidated Statements of Operations and Comprehensive Loss for the three and six months ended June 30, 2018 and 2017 (Unaudited) 2 Condensed Consolidated St

September 28, 2018 6-K

ADHD / Alcobra Ltd. 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO SECTION 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of September, 2018 Commission File Number: 001-35932 ARCTURUS THERAPEUTICS LTD. (Exact Name of Registrant as Specified in Its Charter) 10628 Science Center Drive, Suite 250 San Diego, Californi

August 29, 2018 EX-99.3

Arcturus Therapeutics Appoints Andrew Sassine as Interim Chief Financial Officer

EX-99.3 4 e618248ex99-3.htm Arcturus Therapeutics Appoints Andrew Sassine as Interim Chief Financial Officer San Diego, Calif., Aug. 28, 2018 – Arcturus Therapeutics Ltd. (NASDAQ: ARCT), a leading RNA medicines company, today announced that it has appointed Andrew Sassine as Interim Chief Financial Officer (CFO), effective August 24, 2018. Mr. Sassine has served on Arcturus’ Board of Directors sin

August 29, 2018 EX-99.1

August 29, 2018

August 29, 2018 Securities and Exchange Commission 100 F Street, N.E Washington, DC 20549 Ladies and Gentlemen: We have read Form 6-K dated August 29, 2018, of Arcturus Therapeutics Ltd. and are in agreement with such statements concerning our firm. We have no basis to agree or disagree with other statements of the registrant contained therein. Very truly yours, /s/ Kost Forer Gabbay & Kasierer Ko

August 29, 2018 EX-99.2

Arcturus Therapeutics Announces Appointment of Ernst & Young LLP as the Company’s Independent Auditor

EX-99.2 3 e618248ex99-2.htm Arcturus Therapeutics Announces Appointment of Ernst & Young LLP as the Company’s Independent Auditor San Diego, California, August 29, 2018 – Arcturus Therapeutics Ltd. (“Arcturus” or the “Company”) (NASDAQ: ARCT), a leading RNA medicines company, today announced that at the Company’s Annual General Meeting of Shareholders on August 24, 2018, shareholders of the Compan

August 29, 2018 6-K

ADHD / Alcobra Ltd. 6-K (Current Report of Foreign Issuer)

6-K 1 e6182486k-at.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of August, 2018 Commission File No. 001-35932 ARCTURUS THERAPEUTICS LTD. (Translation of registrant’s name into English) 10628 Science Center Drive, Suite 250 San Diego, Cal

July 27, 2018 EX-99.4

EX-99.4

July 27, 2018 EX-99.2

APPENDIX A July 13, 2016August 24, 2018 Alcobra Ltd.Arcturus Therapeutics Ltd. (Hereinafter: the “Company”) Amended and Restated Compensation Policy for Company Office Holders (Hereinafter: the “Policy” and/or the “Compensation Policy”)

APPENDIX A July 13, 2016August 24, 2018 Alcobra Ltd.Arcturus Therapeutics Ltd. (Hereinafter: the “Company”) Amended and Restated Compensation Policy for Company Office Holders (Hereinafter: the “Policy” and/or the “Compensation Policy”) 1. The Objective of the Document The objective of this document is to define and describe the Company and its subsidiaries’s Office Holder compensation policy as r

July 27, 2018 EX-99.1

ARCTURUS THERAPEUTICS LTD. 10628 Science Center Drive, Suite 200, San Diego, CA 92121 Tel: (858) 900-2660 July 27, 2018 NOTICE OF ANNUAL AND EXTRAORDINARY GENERAL MEETING OF SHAREHOLDERS TO BE HELD ON AUGUST 24, 2018

EX-99.1 2 e618195ex99-1.htm ARCTURUS THERAPEUTICS LTD. 10628 Science Center Drive, Suite 200, San Diego, CA 92121 Tel: (858) 900-2660 July 27, 2018 NOTICE OF ANNUAL AND EXTRAORDINARY GENERAL MEETING OF SHAREHOLDERS TO BE HELD ON AUGUST 24, 2018 Notice is hereby given that an Annual and Extraordinary General Meeting (the “Meeting”) of the Shareholders of Arcturus Therapeutics Ltd. (the “Company”),

July 27, 2018 6-K

ADHD / Alcobra Ltd. 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of July, 2018 (Report No. 3) Commission File No. 001-35932 ARCTURUS THERAPEUTICS LTD. (Translation of registrant’s name into English) 10628 Science Center Drive, Suite 250 San Diego, California 92

July 27, 2018 EX-99.3

APPENDIX B ARCTURUS THERAPEUTICS LTD. 2018 OMNIBUS EQUITY INCENTIVE PLAN TABLE OF CONTENTS

APPENDIX B ARCTURUS THERAPEUTICS LTD. 2018 OMNIBUS EQUITY INCENTIVE PLAN TABLE OF CONTENTS PAGE Article 1. Effective Date, Objectives and Duration 1 1.1 Effective Date of the Plan 1 1.2 Objectives of the Plan 1 1.3 Duration of the Plan 1 Article 2. Definitions 1 2.1 “Affiliate” 1 2.2 “Award” 1 2.3 “Award Agreement” 1 2.4 “Board” 1 2.5 “Bonus Shares” 1 2.6 “Cause” 2 2.7 “Change in Control” 2 2.8 “C

July 20, 2018 EX-99.1

ARCTURUS THERAPEUTICS LTD. 10628 Science Center Drive, Suite 250, San Diego, CA 92121 Tel: (858) 900-2666 July 20, 2018 ARCTURUS THERAPEUTICS ANNOUNCES annual and EXTRAORDINARY GENERAL MEETING OF SHAREHOLDERS TO BE HELD ON AUGUST 24, 2018

EX-99.1 2 e618182ex99-1.htm ARCTURUS THERAPEUTICS LTD. 10628 Science Center Drive, Suite 250, San Diego, CA 92121 Tel: (858) 900-2666 July 20, 2018 ARCTURUS THERAPEUTICS ANNOUNCES annual and EXTRAORDINARY GENERAL MEETING OF SHAREHOLDERS TO BE HELD ON AUGUST 24, 2018 San Diego, California July 20, 2018 - Arcturus Therapeutics Ltd. (“Arcturus” or the “Company”) (NASDAQ:ARCT), an RNA medicines compan

July 20, 2018 6-K

ADHD / Alcobra Ltd. 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of July, 2018 (Report No. 2) Commission File No. 001-35932 ARCTURUS THERAPEUTICS LTD. (Translation of registrant’s name into English) 10628 Science Center Drive, Suite 250 San Diego, California 92

July 10, 2018 EX-99.1

Arcturus Therapeutics Announces Results of Extraordinary General Meeting of Shareholders All Four Proposals Approved by Shareholders

Arcturus Therapeutics Announces Results of Extraordinary General Meeting of Shareholders All Four Proposals Approved by Shareholders San Diego, CA – July 9, 2018 – Arcturus Therapeutics Ltd.

July 10, 2018 6-K

ADHD / Alcobra Ltd. 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of July, 2018 Commission File No. 001-35932 ARCTURUS THERAPEUTICS LTD. (Translation of registrant’s name into English) 10628 Science Center Drive, Suite 250 San Diego, California 92121 (Address of

July 10, 2018 EX-4.14

License Agreement, by and between Arcturus Therapeutics, Inc., as successor-in-interest to Marina Biotech, Inc., and Protiva Biotherapeutics Inc., dated as of November 28, 2012. Incorporated by reference to Exhibit 4.14 to Form 20-F/A filed on July 10, 2018 (File No. 001-35932).

EX-4.14 2 arct-ex4147.htm EX-4.14 Exhibit 4.14 ***Text Omitted and Filed Separately with the Securities and Exchange Commission. Confidential Treatment Requested Under 17 C.F.R. Sections 200.80(b)(4) and Rule 24b-2 EXECUTION COPY License Agreement By and Between Protiva Biotherapeutics Inc. And Marina Biotech, Inc. TABLE OF CONTENTS Article 1 DEFINITIONS AND INTERPRETATION 1 1.1 Definitions 1 1.2

July 10, 2018 EX-12.4

Certification of the Principal Financial Officer pursuant to Rule 13a-14(a) of the Securities Exchange Act of 1934.

Exhibit 12.4 CERTIFICATION PURSUANT TO EXCHANGE ACT RULE 13a-14(a) or 15d-14(a) I, K.C. Kummerfeld, certify that: 1. I have reviewed this Amendment No. 1 to the annual report on Form 20-F of Arcturus Therapeutics Ltd.; and 2. Based on my knowledge, this annual report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in

July 10, 2018 20-F/A

ADHD / Alcobra Ltd. 20-F/A

q UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 20-F/A (Amendment No. 1) ☐ REGISTRATION STATEMENT PURSUANT TO SECTIONS 12(b) OR 12(g) OF THE SECURITIES EXCHANGE ACT OF 1934 OR ☑ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Fiscal Year Ended December 31, 2017 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE

July 10, 2018 EX-12.3

Certification of the Principal Executive Officer pursuant to Rule 13a-14(a) of the Securities Exchange Act of 1934.

arct-ex123_8.htm Exhibit 12.3 CERTIFICATION PURSUANT TO EXCHANGE ACT RULE 13a-14(a) or 15d-14(a)

June 15, 2018 EX-99.2

ARCTURUS THERAPEUTICS LTD.

Fitch Proof - 92892-Arcturus Therapeutics Proxy Card Rev 08 - Front YOUR VOTE IS IMPORTANT.

June 15, 2018 EX-99.1

ARCTURUS THERAPEUTICS LTD. 10628 Science Center Drive, Suite 200, San Diego, CA 92121 Tel: (858) 900-2660 June 14, 2018 EXTRAORDINARY GENERAL MEETING OF SHAREHOLDERS TO BE HELD ON JULY 5, 2018

ARCTURUS THERAPEUTICS LTD. 10628 Science Center Drive, Suite 200, San Diego, CA 92121 Tel: (858) 900-2660 June 14, 2018 EXTRAORDINARY GENERAL MEETING OF SHAREHOLDERS TO BE HELD ON JULY 5, 2018 Dear Arcturus Therapeutics Ltd. Shareholders: We cordially invite you to attend an Extraordinary General Meeting of Shareholders (or the Meeting), of Arcturus Therapeutics Ltd. (or the Company), to be held a

June 15, 2018 6-K

ADHD / Alcobra Ltd. 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of June, 2018 Commission File No. 001-35932 ARCTURUS THERAPEUTICS LTD. (Translation of registrant’s name into English) 10628 Science Center Drive, Suite 250 San Diego, California 92121 (Address of

June 11, 2018 SC 13G

ARCT / Arcturus Therapeutics Ltd. / Brosh Capital Partners L.p. - THE SCHEDULE 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b) (Amendment No. )1 Arcturus Therapeutics Ltd (Name of Issuer) Ordinary Shares, par value of NIS 0.07 (Title of Class of Securities) M1492T105 (CUSIP Number) J

June 11, 2018 EX-99.1

Joint Filing Agreement

Exhibit 99.1 Joint Filing Agreement The undersigned hereby agree that the Statement on Schedule 13G dated June 11, 2018 with respect to the Ordinary Shares, par value of NIS 0.07, of Arcturus Therapeutics Ltd., and any further amendments thereto executed by each and any of the undersigned shall be filed on behalf of each of the undersigned pursuant to and in accordance with the provisions of Rule

May 31, 2018 6-K

ADHD / Alcobra Ltd. 6-K (Current Report of Foreign Issuer)

6-K 1 e6180656k-at.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May, 2018 (Report No. 5) Commission File No. 001-35932 ARCTURUS THERAPEUTICS LTD. (Translation of registrant’s name into English) 10628 Science Center Drive, Suite 250 Sa

May 31, 2018 EX-99.2

Irrevocable Proxy and Power of Attorney

EX-99.2 3 e618065ex99-2.htm Irrevocable Proxy and Power of Attorney The undersigned, [full name] (the “Appointer”), a shareholder in Arcturus Therapeutics Ltd, a company incorporated under the laws of the State of Israel, company number 514098995 (the “Company”), hereby provides this Irrevocable Proxy and Power of Attorney (the “Irrevocable Proxy”). The Appointer is the holder of Ordinary Shares o

May 31, 2018 EX-99.1

Arcturus Therapeutics Announces Extraordinary General Meeting of Shareholders

EX-99.1 2 e618065ex99-1.htm Arcturus Therapeutics Announces Extraordinary General Meeting of Shareholders SAN DIEGO, May 30, 2018 (GLOBE NEWSWIRE) - Arcturus Therapeutics Ltd. (“Arcturus” or the “Company”) (NASDAQ:ARCT), an RNA medicines company, today announced that the Extraordinary General Meeting of the Shareholders of the Company that was announced on May 21, 2018 and was scheduled to be held

May 31, 2018 EX-99.3

Industry veteran Dr. Peter Farrell named as Chairman of the Board, Dr. Pad Chivukula reinstated as CSO and COO

EX-99.3 4 e618065ex99-3.htm Arcturus Announces Management Appointments; Company Founder Joseph E. Payne Reinstated as President and CEO Industry veteran Dr. Peter Farrell named as Chairman of the Board, Dr. Pad Chivukula reinstated as CSO and COO SAN DIEGO, May 31, 2018 (GLOBE NEWSWIRE) - Arcturus Therapeutics Ltd. (NASDAQ:ARCT), a leading RNA medicines company, today announced that Dr. Peter Farr

May 29, 2018 EX-99.2

Arcturus Therapeutics Appoints Four New Directors and Reaches Settlement Agreement with Founder Joseph E. Payne

Exhibit 99.2 Arcturus Therapeutics Appoints Four New Directors and Reaches Settlement Agreement with Founder Joseph E. Payne SAN DIEGO, May 29, 2018 (GLOBE NEWSWIRE) - Arcturus Therapeutics Ltd. (NASDAQ:ARCT) (“Arcturus” or the “Company), a leading RNA medicines company, today announced that, as part of a settlement agreement, it has appointed four new independent directors, Dr. Peter Farrell, Mr.

May 29, 2018 6-K

ADHD / Alcobra Ltd. 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of May, 2018 (Report No. 4) Commission File No. 001-35932 ARCTURUS THERAPEUTICS LTD. (Translation of registrant’s name into English) 10628 Science Center Drive, Suite 250 San Diego, California 921

May 29, 2018 EX-99.1

AGREEMENT AND RELEASE

Exhibit 99.1 AGREEMENT AND RELEASE This Agreement and Release (this “Agreement”) is made and entered into as of the Agreement Date (defined below), by and among Arcturus Therapeutics Ltd. (the “Company”), Arcturus Therapeutics, Inc., a wholly-owned subsidiary of the Company (“THI”), Stuart Collinson (“Collinson”), Craig Willett (Willett”), Daniel Geffken (“Geffken”), David Shapiro (“Shapiro”), Jos

May 24, 2018 6-K

ADHD / Alcobra Ltd. FORM 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of: May 2018 (Report No. 3) Commission File Number 001-35932 ARCTURUS THERAPEUTICS LTD. (Translation of Registrant’s name into English) 10628 Science Center Drive, Suite 250 San Diego, California 921

May 24, 2018 EX-99.1

UNITED STATES DISTRICT COURT SOUTHERN DISTRICT OF CALIFORNIA

Exhibit 99.1 Case 3:18-cv-00766-MMA-NLS Document 40 Filed 05/22/18 PageID.855 Page 1 of 19 UNITED STATES DISTRICT COURT SOUTHERN DISTRICT OF CALIFORNIA ARCTURUS THERAPEUTICS LTD., Case No.: 18cv766-MMA (NLS) Plaintiff, ORDER GRANTING IN PART AND v. DENYING IN PART PLAINTIFF'S MOTION FOR PRELIMINARY JOSEPH E. PAYNE; PETER FARRELL; INJUNCTION AND EXPEDITED ANDREW SASSINE; BRADLEY DISCOVERY SORENSON;

May 24, 2018 EX-99.A

UNITED STATES DISTRICT COURT FOR THE SOUTHERN DISTRICT OF CALIFORNIA

EX-99.A 2 exato13da11164300305242018.htm COMPLAINT Exhibit A Case 3:18-cv-00766-MMA-NLS Document 1 Filed 04/19/18 PageID.1 Page 1 of 17 Michael L. Charlson, CA Bar No. 122125 [email protected] Mortimer H. Hartwell, CA Bar No. 154556 [email protected] VINSON & ELKINS L.L.P. 555 Mission Street, Suite 2000 San Francisco, CA 94105 Tel: (415) 979-6900 / Fax: (415) 651-8786 Ari Berman (pro hac vice

May 24, 2018 SC 13D/A

ARCT / Arcturus Therapeutics Ltd. / Sorenson Bradley T. - AMENDMENT NO. 1 TO THE SCHEDULE 13D Activist Investment

SC 13D/A 1 sc13da11164300305242018.htm AMENDMENT NO. 1 TO THE SCHEDULE 13D UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) (Amendment No. 1)1 Arcturus Therapeutics Ltd. (Name of Issuer) Ordinary Shares, par value of NI

May 23, 2018 SC 13D/A

ARCT / Arcturus Therapeutics Ltd. / Payne Joseph E Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) (Amendment No. 8)* Arcturus Therapeutics Ltd. (Name of Issuer) Ordinary Shares, par value of NIS 0.07 (Title of Class of Securities) M1492T105 (CUSIP Number) Jeffrey Baum

May 23, 2018 EX-99.K

Arcturus Therapeutics Founder Joseph Payne Calls for an End to Company’s Frivolous and Costly Lawsuits; Applauds Court Decision and Welcomes June 25, 2018 EGM Date

EXHIBIT K Arcturus Therapeutics Founder Joseph Payne Calls for an End to Company’s Frivolous and Costly Lawsuits; Applauds Court Decision and Welcomes June 25, 2018 EGM Date · Applauds court decision to require disclosure of complaint filed against Joe Payne and other Arcturus shareholders as reasonable solution to end costly securities litigation · Welcomes Israeli Court order that forced Arcturus Board to set date for Extraordinary General Meeting (“EGM”) of shareholders for June 25, 2018 SAN DIEGO, May 23, 2018 (GLOBE NEWSWIRE) - Joseph Payne, Founder and largest shareholder of Arcturus Therapeutics Ltd.

May 23, 2018 EX-99.L

UNITED STATES DISTRICT COURT FOR THE SOUTHERN DISTRICT OF CALIFORNIA

Case 3:18-cv-00766-MMA-NLS Document 1 Filed 04/19/18 PageID.1 Page 1 of 17 Michael L. Charlson, CA Bar No. 122125 [email protected] Mortimer H. Hartwell, CA Bar No. 154556 [email protected] VINSON & ELKINS L.L.P. 555 Mission Street, Suite 2000 San Francisco, CA 94105 Tel: (415) 979-6900 / Fax: (415) 651-8786 Ari Berman (pro hac vice to be filed) [email protected] Lawrence S. Elbaum (pro hac vi

May 21, 2018 6-K

ADHD / Alcobra Ltd. FORM 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of: May 2018 (Report No. 2) Commission File Number 001-35932 ARCTURUS THERAPEUTICS LTD. (Translation of Registrant’s name into English) 10628 Science Center Drive, Suite 250 San Diego, California 921

May 21, 2018 EX-99.1

10628 Science Center Drive, Suite 250, San Diego, California 92121 Tel: (858) 900-2660 ARCTURUS THERAPEUTICS Announces EXTRAORDINARY General Meeting of Shareholders Board of Directors Recommends Removal of Terminated CEO Joseph Payne from Board of Di

Exhibit 99.1 10628 Science Center Drive, Suite 250, San Diego, California 92121 Tel: (858) 900-2660 ARCTURUS THERAPEUTICS Announces EXTRAORDINARY General Meeting of Shareholders Board of Directors Recommends Removal of Terminated CEO Joseph Payne from Board of Directors San Diego, California, May 21, 2018—Arcturus Therapeutics Ltd. (Arcturus or the Company) (NASDAQ: ARCT), an RNA medicines company

May 15, 2018 SC 13D/A

ARCT / Arcturus Therapeutics Ltd. / Payne Joseph E Activist Investment

SC 13D/A 1 e618008sc13da-at.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) (Amendment No. 7)* Arcturus Therapeutics Ltd. (Name of Issuer) Ordinary Shares, par value of NIS 0.07 (Title of Class of Securities) M1492

May 15, 2018 EX-99.J

Arcturus Therapeutics Founder Joseph Payne Welcomes Court Decision to Set Date and Agenda of Extraordinary General Meeting to Vote for New Board Members

EX-99.J 2 e618008ex-j.htm EXHIBIT J Arcturus Therapeutics Founder Joseph Payne Welcomes Court Decision to Set Date and Agenda of Extraordinary General Meeting to Vote for New Board Members · Court rules that a notification for Extraordinary General Meeting must be issued this week · The Extraordinary General Meeting to be scheduled between June 18 and June 24, 2018 · Court ruling also establishes

May 14, 2018 6-K

ADHD / Alcobra Ltd. FORM 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of: May 2018 (Report No. 1) Commission File Number 001-35932 ARCTURUS THERAPEUTICS LTD. (Translation of Registrant’s name into English) 10628 Science Center Drive, Suite 200 San Diego, California 921

May 14, 2018 EX-99.1

Arcturus Therapeutics Files Form 20-F

EX-99.1 2 tv494141ex99-1.htm EXHIBIT 99.1 Exhibit 99.1 FOR IMMEDIATE RELEASE Arcturus Therapeutics Files Form 20-F San Diego, CA – May 14, 2018 – Arcturus Therapeutics Ltd. (NASDAQ: ARCT), a leading RNA medicines company, today announced the filing of the Company’s Annual Report on Form 20-F for the fiscal year ended December 31, 2017 with the U.S. Securities and Exchange Commission on May 14, 201

May 14, 2018 20-F

ADHD / Alcobra Ltd. 20-F

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 20-F ☐ REGISTRATION STATEMENT PURSUANT TO SECTIONS 12(b) OR 12(g) OF THE SECURITIES EXCHANGE ACT OF 1934 OR ☑ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Fiscal Year Ended December 31, 2017 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE AC

May 14, 2018 EX-4.14

License Agreement, by and between Arcturus Therapeutics, Inc., as successor-in-interest to Marina Biotech, Inc., and Protiva Biotherapeutics Inc., dated as of November 28, 2012.

Exhibit 4.14 ***Text Omitted and Filed Separately with the Securities and Exchange Commission. Confidential Treatment Requested Under 17 C.F.R. Sections 200.80(b)(4) and Rule 24b-2 EXECUTION COPY License Agreement By and Between Protiva Biotherapeutics Inc. And Marina Biotech, Inc. TABLE OF CONTENTS Article 1 DEFINITIONS AND INTERPRETATION 2 1.1 Definitions 2 1.2 Interpretation 9 Article 2 LICENSE

May 14, 2018 EX-4.13

Co-Development and Co-Commercialization Agreement, by and between Arcturus Therapeutics, Inc. and CureVac AG, dated January 1, 2018. Incorporated by reference to Exhibit 4.13 to Form 20-F filed on May 14, 2018 (File No. 001-35932).

Exhibit 4.13 ***Text Omitted and Filed Separately with the Securities and Exchange Commission. Confidential Treatment Requested Under 17 C.F.R. Sections 200.80(b)(4) and Rule 24b-2 CO-DEVELOPMENT AND CO-COMMERCIALIZATION AGREEMENT between CUREVAC and ARCTURUS Confidential Execution Copy CO-DEVELOPMENT AND CO-COMMERCIALIZATION AGREEMENT This CO-DEVELOPMENT AND CO-COMMERCIALIZATION AGREEMENT (this “

May 14, 2018 EX-4.6

Lease Agreement, by and between Arcturus Therapeutics, Inc. and ARE-SD Region No. 44, LLC, dated October 4, 2017.

Exhibit 4.6 LEASE AGREEMENT THIS LEASE AGREEMENT (this “Lease”) is made this 4th day of October, 2017, between ARE-SD REGION NO. 44, LLC, a Delaware limited liability company (“Landlord”), and ARCTURUS THERAPEUTICS, INC., a Delaware corporation (“Tenant”). Building: 10628 Science Center Drive, San Diego, California Premises: That portion of the Project, containing approximately 24,705 rentable squ

May 14, 2018 EX-4.11

Letter Agreement, by and between Arcturus Therapeutics, Inc. and Cystic Fibrosis Foundation Therapeutics, Inc., dated May 16, 2017. Incorporated by reference to Exhibit 4.11 to Form 20-F filed on May 14, 2018 (File No. 001-35932).

Exhibit 4.11 ***Text Omitted and Filed Separately with the Securities and Exchange Commission. Confidential Treatment Requested Under 17 C.F.R. Sections 200.80(b)(4) and Rule 24b-2 CFFT FINAL 5/16/17 May 16, 2017 Padmanabh Chivukula, PhD Arcturus Therapeutics, Inc. 10628 Science Center Dr., Suite 200 San Diego, CA 92121 Development Program: Nebulized LUNAR-formulated CFTR mRNA Amount of Award: $3,

May 14, 2018 EX-4.12

Development and Option Agreement, by and between Arcturus Therapeutics, Inc. and CureVac AG, dated January 1, 2018, as amended May 3, 2018. Incorporated by reference to Exhibit 4.12 to Form 20-F filed on May 14, 2018 (File No. 001-35932).

Exhibit 4.12 ***Text Omitted and Filed Separately with the Securities and Exchange Commission. Confidential Treatment Requested Under 17 C.F.R. Sections 200.80(b)(4) and Rule 24b-2 Execution Copy Development and Option Agreement by and between CureVac AG and Arcturus Therapeutics Inc. dated 1 January 2018 Development and Option Agreement between CureVac AG and Arcturus Therapeutics Inc Table of Co

May 14, 2018 EX-15.1

Consent of Ernst & Young LLP.

Exhibit 15.1 CONSENT OF INDEPENDENT REGISTERED ACCOUNTING FIRM We consent to the incorporation by reference in the Registration Statement on Form F-3 (Registration No. 333-209960) and Registration Statements on Form S-8 (Registration No’s. 333-194875, 333-202394, 333-209947, 333-217556, and 333-221830) of Arcturus Therapeutics Ltd. (formerly Alcobra Ltd.) of our report dated May 14, 2018 with resp

May 14, 2018 EX-13.2

Certification of the Principal Financial Officer pursuant to 18 U.S.C. 1350.

Exhibit 13.2 CERTIFICATION PURSUANT TO 18 U.S.C. Section 1350 In connection with the filing of the Annual Report on Form 20-F for the period ended December 31, 2017 (the “Report”) by Arcturus Ltd. (the "Company"), the undersigned, as Vice President, Finance & Operations of the Company, hereby certifies pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act

May 14, 2018 EX-15.2

Consent of Kost, Forer, Gabbay & Kasierer.

Exhibit 15.2 CONSENT OF INDEPENDENT REGISTERED ACCOUNTING FIRM We consent to the incorporation by reference in the Registration Statement on Form F-3 (Registration No. 333-209960) and Registration Statements on Form S-8 (Registration No’s. 333-194875, 333-202394, 333-209947 333-217556, and 333-221830) of Arcturus Therapeutics Ltd. of our report dated May 14, 2018 with respect to the consolidated f

May 14, 2018 EX-3.1

Voting Trust Agreement, dated February 11, 2018, by and among the Company, Padmanabh Chivukula, and Mark Herbert

Exhibit 3.1 VOTING TRUST AGREEMENT This Voting Trust Agreement (this “Agreement”) is made and entered into effective for all purposes and in all respects as of February 11, 2018 by and among (i) Arcturus Therapeutics Ltd., an Israeli company, or its successors and assigns (the “Company”), (ii) Padmanabh Chivukula (the “Shareholder”), and (iii) the then-acting Principal Executive Officer (defined b

May 14, 2018 EX-4.8

Research and Exclusive License Agreement, by and between Arcturus Therapeutics, Inc. and Synthetic Genomics, Inc., effective October 24, 2017. Incorporated by reference to Exhibit 4.8 to Form 20-F filed on May 14, 2018 (File No. 001-35932)

Exhibit 4.8 CONFIDENTIAL ***Text Omitted and Filed Separately with the Securities and Exchange Commission. Confidential Treatment Requested Under 17 C.F.R. Sections 200.80(b)(4) and Rule 24b-2 Research and exclusive LICENSE AGREEMENT This Research and Exclusive License Agreement (“Agreement”) is entered into by and between Arcturus Therapeutics, Inc., a Delaware corporation (“Arcturus”), and Synth

May 14, 2018 EX-4.10

Research Collaboration and License Agreement, by and between Arcturus Therapeutics, Inc. and Ultragenyx Pharmaceutical Inc., entered into as of October 26, 2015, as amended October 17, 2017 and April 20, 2018. Incorporated by reference to Exhibit 4.10 to Form 20-F filed on May 14, 2018 (File No. 001-35932).

Exhibit 4.10 ***Text Omitted and Filed Separately with the Securities and Exchange Commission. Confidential Treatment Requested Under 17 C.F.R. Sections 200.80(b)(4) and Rule 24b-2 Confidential RESEARCH COLLABORATION AND LICENSE AGREEMENT This Research Collaboration and License Agreement (this “Agreement”) is entered into as of October 26, 2015 (the “Effective Date”) by and between Ultragenyx Phar

May 14, 2018 EX-4.9

Research Agreement, by and between Arcturus Therapeutics, Inc. and Millennium Pharmaceuticals, Inc., a wholly-owned subsidiary of Takeda Pharmaceutical Company Limited, effective December 6, 2016, as amended December 21, 2017. Incorporated by reference to Exhibit 4.9 to Form 20-F filed on May 14, 2018 (File No. 001-35932).

Exhibit 4.9 ***Text Omitted and Filed Separately with the Securities and Exchange Commission. Confidential Treatment Requested Under 17 C.F.R. Sections 200.80(b)(4) and Rule 24b-2 COVERSHEET RESEARCH AGREEMENT Arcturus Therapeutics, Inc., a corporation organized and existing under the laws of Delaware, USA and having its registered office at 10628 Science Center Drive Suite 200, San Diego, Califor

May 14, 2018 EX-4.7

Research Collaboration and License Agreement, by and between Arcturus Therapeutics, Inc. and Janssen Pharmaceuticals, Inc., dated October 18, 2017. Incorporated by reference to Exhibit 4.7 to Form 20-F filed on May 14, 2018 (File No. 001-35932).

Exhibit 4.7 EXECUTION COPY ***Text Omitted and Filed Separately with the Securities and Exchange Commission. Confidential Treatment Requested Under 17 C.F.R. Sections 200.80(b)(4) and Rule 24b-2 RESEARCH COLLABORATION AND LICENSE AGREEMENT Between Arcturus Therapeutics, Inc. And Janssen Pharmaceuticals, Inc. i EXECUTION COPY INDEX OF DEFINITIONS ADT 35 FTE Rate 39 Affiliate 34 GLP 40 After-Acquire

May 14, 2018 EX-12.1

Certification of the Principal Executive Officer pursuant to Rule 13a-14(a) of the Securities Exchange Act of 1934.

Exhibit 12.1 CERTIFICATION PURSUANT TO EXCHANGE ACT RULE 13a-14(a) or 15d-14(a) I, Mark R. Herbert, certify that: 1. I have reviewed this annual report on Form 20–F of Arcturus Therapeutics Ltd.; 2. Based on my knowledge, this annual report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances

May 14, 2018 EX-13.1

Certification of the Principal Executive Officer pursuant to 18 U.S.C. 1350.

Exhibit 13.1 CERTIFICATION PURSUANT TO 18 U.S.C. Section 1350 In connection with the filing of the Annual Report on Form 20-F for the period ended December 31, 2017 (the “Report”) by Arcturus Therapeutics Ltd. (the "Company"), the undersigned, as Interim President of the Company, hereby certifies pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 20

May 14, 2018 EX-12.2

Certification of the Principal Financial Officer pursuant to Rule 13a-14(a) of the Securities Exchange Act of 1934

Exhibit 12.2 CERTIFICATION PURSUANT TO EXCHANGE ACT RULE 13a-14(a) or 15d-14(a) I, Rebecque Laba, certify that: 1. I have reviewed this annual report on Form 20–F of Arcturus Therapeutics Ltd.; 2. Based on my knowledge, this annual report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances un

May 14, 2018 EX-4.15

Patent Assignment and License Agreement, by and between Arcturus Therapeutics, Inc. and Marina Biotech, Inc., dated as of August 9, 2013. Incorporated by reference to Exhibit 4.15 to Form 20-F filed on May 14, 2018 (File No. 001-35932)

Exhibit 4.15 ***Text Omitted and Filed Separately with the Securities and Exchange Commission. Confidential Treatment Requested Under 17 C.F.R. Sections 200.80(b)(4) and Rule 24b-2 Patent assignment and license agreement By and Between Arcturus therapeutics, inc. And Marina biotech, inc. This PATENT ASSIGNMENT AND LICENSE AGREEMENT, dated August 9, 2013 (“Effective Date”), is entered into by and b

May 14, 2018 EX-15.3

Letter dated May14, 2018 of Ernst & Young LLP, as required by Item 16F of Form 20-F.

Exhibit 15.3 Ernst & Young LLP 4370 La Jolla Village Drive Suite 500 San Diego, CA 92122 Tel: +(858) 535 7200 Fax: +(858) 535 7777 ey.com May 14, 2018 Securities and Exchange Commission 100 F Street, N.E. Washington, DC 20549 Ladies and Gentlemen: We have read Item 16F of Form 20-F dated May 14, 2018, of Arcturus Therapeutics Ltd. and are in agreement with the statements contained in the first and

May 2, 2018 EX-99.I

Arcturus Therapeutics Founder Joseph Payne Successfully Prevents Board’s Egregious Attempt to Dilute Shareholders

EX-99.I 2 e617964ex-i.htm EXHIBIT I Arcturus Therapeutics Founder Joseph Payne Successfully Prevents Board’s Egregious Attempt to Dilute Shareholders · Israeli District Court enjoins attempt by board to dilute shareholders through sale of 24.9% of Arcturus share capital · Court found sufficient evidence to support the claim that the members of the Arcturus board are motivated by their own self-int

May 2, 2018 SC 13D/A

ARCT / Arcturus Therapeutics Ltd. / Payne Joseph E Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) (Amendment No. 6)* Arcturus Therapeutics Ltd. (Name of Issuer) Ordinary Shares, par value of NIS 0.07 (Title of Class of Securities) M1492T105 (CUSIP Number) Jeffrey Baum

April 30, 2018 SC 13D

ARCT / Arcturus Therapeutics Ltd. / Brosh Capital Partners L.p. - THE SCHEDULE 13D Activist Investment

SC 13D 1 sc13d1124700204302018.htm THE SCHEDULE 13D UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) (Amendment No. )1 Arcturus Therapeutics Ltd. (Name of Issuer) Ordinary Shares, par value of NIS 0.07 (Title of Class o

April 30, 2018 EX-99.1

JOINT FILING AGREEMENT

EX-99.1 2 ex991to13d1124700204302018.htm JOINT FILING AGREEMENT Exhibit 99.1 JOINT FILING AGREEMENT In accordance with Rule 13d-1(k)(1)(iii) under the Securities Exchange Act of 1934, as amended, the persons named below agree to the joint filing on behalf of each of them of a Statement on Schedule 13D (including amendments thereto) with respect to the shares of Ordinary Shares, par value NIS 0.07,

April 27, 2018 NT 20-F

ADHD / Alcobra Ltd. FORM 12B-25

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 OMB APPROVAL FORM 12b-25 OMB Number:…….3235-0058 Expires: October 31, 2018 NOTIFICATION OF LATE FILING Estimated average burden hours per response..........2.50 SEC FILE NUMBER 001-35932 CUSIP NUMBER (Check one): ¨ Form10 K x Form 20-F ¨ Form 11-K ¨ Form 10-Q ¨ Form 10-D ¨ Form N-SAR ¨ Form N-CSR For Period Ended: December 31,

April 23, 2018 EX-99.H

Arcturus Therapeutics Founder Joseph Payne Dismisses Board’s Baseless Lawsuit as Desperate Entrenchment Tactic

EXHIBIT H Arcturus Therapeutics Founder Joseph Payne Dismisses Board’s Baseless Lawsuit as Desperate Entrenchment Tactic · Warns lawsuit is another attempt by Arcturus’ board to distract shareholders from the Company’s abhorrent governance deficiencies · Calls on board to respect the rights of all shareholders and immediately set date for Extraordinary General Meeting SAN DIEGO, April 23, 2018 (GLOBE NEWSWIRE) - Joseph Payne, Founder and largest shareholder of Arcturus Therapeutics Ltd.

April 23, 2018 SC 13D/A

ARCT / Arcturus Therapeutics Ltd. / Payne Joseph E Activist Investment

SC 13D/A 1 e617939sc13da-at.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) (Amendment No. 5)* Arcturus Therapeutics Ltd. (Name of Issuer) Ordinary Shares, par value of NIS 0.07 (Title of Class of Securities) M1492

April 19, 2018 SC 13D/A

ARCT / Arcturus Therapeutics Ltd. / Payne Joseph E Activist Investment

SC 13D/A 1 e617924sc13da-at.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) (Amendment No. 4)* Arcturus Therapeutics Ltd. (Name of Issuer) Ordinary Shares, par value of NIS 0.07 (Title of Class of Securities) M1492

April 19, 2018 EX-99.G

April 18, 2018

EXHIBIT G April 18, 2018 To: The Board of Directors Arcturus Therapeutics Ltd. do Meitar Liquomik Geva Leshem Tal [email protected] 16 Abba Hillel Road, 12th Floor Ramat Gan 5250608 [email protected] 10628 Science Center Drive San Diego CA 92121 U.S.A. By Email and Courier Re: Restated Demand to Convene an Extraordinary General Meeting Dear Sirs, 1. By letter dated February 12, 2018[1] and a

April 13, 2018 SC 13D/A

ARCT / Arcturus Therapeutics Ltd. / Payne Joseph E Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) (Amendment No. 3)* Arcturus Therapeutics Ltd. (Name of Issuer) Ordinary Shares, par value of NIS 0.07 (Title of Class of Securities) M1492T105 (CUSIP Number) Jeffrey Baum

April 13, 2018 EX-99.F

Arcturus Therapeutics Founder Joseph Payne Disappointed by Board’s Desperate Attempt to Delay Meeting and Avoid Shareholder Accountability

EX-99.F 2 e617906ex-f.htm EXHIBIT F Arcturus Therapeutics Founder Joseph Payne Disappointed by Board’s Desperate Attempt to Delay Meeting and Avoid Shareholder Accountability · Change in Arcturus board is needed on an urgent basis to improve the company’s performance · Board’s decision to indefinitely delay inevitable change is a clear act of entrenchment · Overwhelming support for Mr. Payne’s nom

April 9, 2018 6-K

ADHD / Alcobra Ltd. 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of: April 2018 (Report No. 2) Commission File Number 001-35932 ARCTURUS THERAPEUTICS LTD. (Translation of Registrant’s name into English) 10628 Science Center Drive, Suite 200 San Diego, California 9

April 9, 2018 EX-99.1

Arcturus Therapeutics Issues Statement Regarding Timing of Extraordinary General Meeting of Shareholders Postponement due to Joseph Payne’s Focus on Advancing His Personal Agenda at the Expense of Arcturus Shareholders

Exhibit 99.1 FOR IMMEDIATE RELEASE Arcturus Therapeutics Issues Statement Regarding Timing of Extraordinary General Meeting of Shareholders Postponement due to Joseph Payne’s Focus on Advancing His Personal Agenda at the Expense of Arcturus Shareholders San Diego, CA – April 8, 2018 – Arcturus Therapeutics Ltd. (NASDAQ: ARCT), a leading RNA medicines company, today announced that upon the recommen

April 9, 2018 SC 13G

ARCT / Arcturus Therapeutics Ltd. / Brosh Capital Partners L.p. - THE SCHEDULE 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b) (Amendment No. )1 Arcturus Therapeutics Ltd. (Name of Issuer) Ordinary Shares, par value of NIS 0.07 (Title of Class of Securities) M1492T105 (CUSIP Number)

April 9, 2018 EX-99.1

Joint Filing Agreement

Exhibit 99.1 Joint Filing Agreement The undersigned hereby agree that the Statement on Schedule 13G dated April 9, 2018 with respect to the Ordinary Shares, par value of NIS 0.07, of Arcturus Therapeutics Ltd., and any further amendments thereto executed by each and any of the undersigned shall be filed on behalf of each of the undersigned pursuant to and in accordance with the provisions of Rule

April 4, 2018 SC 13D/A

ARCT / Arcturus Therapeutics Ltd. / Payne Joseph E Activist Investment

SC 13D/A 1 e617877sc13da-at.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) (Amendment No. 2)* Arcturus Therapeutics Ltd. (Name of Issuer) Ordinary Shares, par value of NIS 0.07 (Title of Class of Securities) M1492

April 4, 2018 EX-99.E

EXHIBIT E

EX-99.E 2 e617877ex-e.htm EXHIBIT E April 3, 2018 To: Arcturus Therapeutics Ltd. Stuart Collinson, Executive Chairman of the Board Craig Willett, Director Daniel Geffken, Director David Shapiro, Director 10628 Science Center Drive San Diego, CA 92121 I founded Arcturus Therapeutics in 2013 to discover novel RNA therapeutics for diseases for which there is no adequate treatment. Through all of this

April 2, 2018 6-K

ADHD / Alcobra Ltd. FORM 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of: April 2018 (Report No. 1) Commission File Number 001-35932 ARCTURUS THERAPEUTICS LTD. (Translation of Registrant’s name into English) 10628 Science Center Drive, Suite 200 San Diego, California 9

April 2, 2018 EX-99.1

To: Arcturus Therapeutics Ltd. Employees

Exhibit 99.1 To: Arcturus Therapeutics Ltd. Employees From: Mark Herbert, Interim President Date: April 2, 2018 Subject: Notes from the Road Hi Team, We are excited to share some of the great progress we have been making at Arcturus across our ongoing preclinical programs and collaborations. We are confident that we are well-positioned to deliver on our objective of developing innovative RNA medic

March 28, 2018 EX-99.1

Arcturus Therapeutics Initiates Lawsuit Against Joseph E. Payne to Protect the Interests of Arcturus Shareholders Complaint Details Extensive Misconduct by Mr. Payne during Tenure as CEO Cites Mr. Payne’s Self-Dealing and Inappropriate Business Confl

Exhibit 99.1 Arcturus Therapeutics Initiates Lawsuit Against Joseph E. Payne to Protect the Interests of Arcturus Shareholders Complaint Details Extensive Misconduct by Mr. Payne during Tenure as CEO Cites Mr. Payne’s Self-Dealing and Inappropriate Business Conflicts of Interest San Diego, CA – March 27, 2018 – Arcturus Therapeutics Ltd. (NASDAQ: ARCT), a leading RNA medicines company, today initi

March 28, 2018 EX-99.2

Arcturus Therapeutics Issues Open Letter to Shareholders Details Former President and CEO Joseph E. Payne’s Poor Judgment, Failed Leadership and Deceit that Led to His Termination for Cause Cites Payne’s Self-Dealing and Blatant Disloyalty to Arcturu

EX-99.2 3 tv489828ex99-2.htm EXHIBIT 99.2 Exhibit 99.2 Arcturus Therapeutics Issues Open Letter to Shareholders Details Former President and CEO Joseph E. Payne’s Poor Judgment, Failed Leadership and Deceit that Led to His Termination for Cause Cites Payne’s Self-Dealing and Blatant Disloyalty to Arcturus, its Shareholders and Collaborators San Diego, CA – March 28, 2018 – Arcturus Therapeutics Lt

March 28, 2018 6-K

ADHD / Alcobra Ltd. FORM 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of: March 2018 (Report No. 2) Commission File Number 001-35932 ARCTURUS THERAPEUTICS LTD. (Translation of Registrant’s name into English) 10628 Science Center Drive, Suite 200 San Diego, California 9

March 12, 2018 EX-99.1

10628 Science Center Drive, Suite 200, San Diego, California 92121 Tel: (858) 900-2660 ARCTURUS THERAPEUTICS Announces EXTRAORDINARY General Meeting of Shareholders Board of Directors Recommends Removal of Terminated CEO Joseph Payne from Board of Di

Exhibit 99.1 10628 Science Center Drive, Suite 200, San Diego, California 92121 Tel: (858) 900-2660 ARCTURUS THERAPEUTICS Announces EXTRAORDINARY General Meeting of Shareholders Board of Directors Recommends Removal of Terminated CEO Joseph Payne from Board of Directors San Diego, California, March 11, 2018—Arcturus Therapeutics Ltd. (Arcturus or the Company) (NASDAQ: ARCT), an RNA medicines compa

March 12, 2018 6-K

ADHD / Alcobra Ltd. 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of: March 2018 (Report No. 1) Commission File Number 001-35932 ARCTURUS THERAPEUTICS LTD. (Translation of Registrant’s name into English) 10628 Science Center Drive, Suite 200 San Diego, California 9

February 28, 2018 6-K

ADHD / Alcobra Ltd. FORM 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of: February 2018 (Report No. 4) Commission File Number 001-35932 ARCTURUS THERAPEUTICS LTD. (Translation of Registrant?s name into English) 10628 Science Center Drive, Suite 200 San Diego, Californi

February 22, 2018 SC 13D

ARCT / Arcturus Therapeutics Ltd. / Chivukula Pad - SCHEDULE 13D Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13D UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No.

February 22, 2018 EX-99.1

JOINT FILING AGREEMENT

EX-99.1 2 tv486660ex99-1.htm EXHIBIT 99.1 EXHIBIT 99.1 JOINT FILING AGREEMENT We, the signatories of the statement on Schedule 13D to which this Agreement is attached, hereby agree that such statement is, and any amendments thereto filed by any of us will be, filed and on behalf of each of us. Date: February 22, 2018 /s/ Padmanabh Chivukula Padmanabh Chivukula /s/ Mark Herbert Mark Herbert

February 22, 2018 EX-99.4

VOTING TRUST AGREEMENT

EX-99.4 3 tv486660ex99-4.htm EXHIBIT 99.4 EXHIBIT 99.4 VOTING TRUST AGREEMENT This Voting Trust Agreement (this “Agreement”) is made and entered into effective for all purposes and in all respects as of February 11, 2018 by and among (i) Arcturus Therapeutics Ltd., an Israeli company, or its successors and assigns (the “Company”), (ii) Padmanabh Chivukula (the “Shareholder”), and (iii) the then-ac

February 13, 2018 6-K

ADHD / Alcobra Ltd. FORM 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of: February 2018 (Report No. 3) Commission File Number 001-35932 ARCTURUS THERAPEUTICS LTD. (Translation of Registrant?s name into English) 10628 Science Center Drive, Suite 200 San Diego, Californi

February 13, 2018 EX-99.D

February 12, 2018

February 12, 2018 To: The Board of Directors Arcturus Therapeutics Ltd. c/o Meitar Liquornik Geva Leshem Tal [email protected] [email protected] 10628 Science Center Drive, Suite 200 16 Abba Hillel Road, 12th Floor San Diego CA 92121 Ramat Gan 5250608 U.S.A. By Email and Courier Re: Demand to Convene an Extraordinary General Meeting Dear Sirs, 1. The undersigned, Mr. Joseph E. Payne, is the

February 13, 2018 SC 13D/A

ARCT / Arcturus Therapeutics Ltd. / Payne Joseph E Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) (Amendment No. 1)* Arcturus Therapeutics Ltd. (Name of Issuer) Ordinary Shares, par value of NIS 0.07 (Title of Class of Securities) M1492T105 (CUSIP Number) Jeffrey Baum

February 13, 2018 SC 13G

ARCT / Arcturus Therapeutics Ltd. / Broadfin Capital, LLC Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No.

February 13, 2018 SC 13G/A

ARCT / Arcturus Therapeutics Ltd. / Baker Brothers Advisors LP - AMENDMENT NO. 1 Passive Investment

SCHEDULE 13G SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 Under the Securities Exchange Act of 1934 (Amendment No.

February 7, 2018 EX-99.1

JOINT FILING AGREEMENT

EX-99.1 2 tv485110ex99-1.htm EXHIBIT 99.1 EXHIBIT 99.1 JOINT FILING AGREEMENT We, the signatories of the statement on Schedule 13D to which this Agreement is attached, hereby agree that such statement is, and any amendments thereto filed by any of us will be, filed and on behalf of each of us. Date: February 7, 2018 /S/ Craig Willett Craig Willett Phoenician Enterprises, Ltd. By: /S/ Craig Willett

February 7, 2018 SC 13D

ARCT / Arcturus Therapeutics Ltd. / Willett Craig - SCHEDULE 13D Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No.

February 6, 2018 EX-99.B

- 1 -

BARN EA Without Prejudice By email Re: Arcturus Therapeutics Ltd. Dear Sirs, This letter is sent to you on behalf of our client, Mr. Joseph Payne, a shareholder, a member of the board of directors (the "Board") and the President and Chief Executive Officer (the "Position") of Arcturus Therapeutics Ltd. (formerly, Alcobra Ltd), Israeli company number 514098995 (the "Company"). Our client is also on

February 6, 2018 EX-99.A

ARCTURUS THERAPEUTICS, INC. COMMON STOCK PURCHASE AGREEMENT

ARCTURUS THERAPEUTICS, INC. COMMON STOCK PURCHASE AGREEMENT This Common Stock Purchase Agreement (this “Agreement”) is made as of March 4, 2013 by and between Arcturus Therapeutics, Inc., a Delaware corporation (the “Company”), and Joseph E. Payne (“Purchaser”). 1. Sale of Stock. Subject to the terms and conditions of this Agreement, simultaneously with the execution and delivery of this Agreement

February 6, 2018 SC 13D

ARCT / Arcturus Therapeutics Ltd. / Payne Joseph E Activist Investment

SC 13D 1 e617632sc13d-at.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) (Amendment No. )* Arcturus Therapeutics Ltd. (Name of Issuer) Ordinary Shares, par value of NIS 0.07 (Title of Class of Securities) M1492T105

February 6, 2018 EX-99.C

Lock-Up Agreement September 27, 2017

EX-99.C 4 e617632ex99-c.htm Lock-Up Agreement September 27, 2017 Ladies and Gentlemen: The undersigned (the “Shareholder”) understands that: (i) Alcobra Ltd., an Israeli company (“Alcobra”), has entered into an Agreement and Plan of Merger and Reorganization, dated as of September 27, 2017 (the “Merger Agreement”), with Arcturus Therapeutics, Inc., a Delaware corporation (“Arcturus”) and Aleph Mer

February 5, 2018 EX-99.2

YOUR VOTE IS IMPORTANT. PLEASE VOTE TODAY. Vote by Internet - QUICK *** EASY IMMEDIATE - 24 Hours a Day, 7 Days a Week or by Mail ARCTURUS THERAPEUTICS LTD. Your Internet vote authorizes the named proxies to vote your shares in the same manner as if

Exhibit 99.2 YOUR VOTE IS IMPORTANT. PLEASE VOTE TODAY. Vote by Internet - QUICK *** EASY IMMEDIATE - 24 Hours a Day, 7 Days a Week or by Mail ARCTURUS THERAPEUTICS LTD. Your Internet vote authorizes the named proxies to vote your shares in the same manner as if you marked, signed and returned your proxy card. Votes submitted electronically over the Internet must be received by 11:59 p.m., Eastern

February 5, 2018 6-K

ADHD / Alcobra Ltd. FORM 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of: February 2018 (Report No. 2) Commission File Number 001-35932 ARCTURUS THERAPEUTICS LTD. (Translation of Registrant?s name into English) 10628 Science Center Drive, Suite 200 San Diego, Californi

February 5, 2018 EX-99.1

ARCTURUS THERAPEUTICS LTD. 10628 Science Center Drive, Suite 200, San Diego, CA 92121 Tel: (858) 900-2660 February 5, 2018 EXTRAORDINARY GENERAL MEETING OF SHAREHOLDERS TO BE HELD ON FEBRUARY 26, 2018

Exhibit 99.1 ARCTURUS THERAPEUTICS LTD. 10628 Science Center Drive, Suite 200, San Diego, CA 92121 Tel: (858) 900-2660 February 5, 2018 EXTRAORDINARY GENERAL MEETING OF SHAREHOLDERS TO BE HELD ON FEBRUARY 26, 2018 Dear Arcturus Therapeutics Ltd. Shareholders: We cordially invite you to attend an Extraordinary General Meeting of Shareholders, or the Meeting, of Arcturus Therapeutics Ltd., or the Co

February 2, 2018 6-K

ADHD / Alcobra Ltd. 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of: February 2018 (Report No. 1) Commission File Number 001-35932 ARCTURUS THERAPEUTICS LTD. (Translation of Registrant?s name into English) 10628 Science Center Drive, Suite 200 San Diego, Californi

January 30, 2018 6-K

ADHD / Alcobra Ltd. FORM 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of: January 2018 (Report No. 2) Commission File Number 001-35932 ARCTURUS THERAPEUTICS LTD. (Translation of Registrant?s name into English) 10628 Science Center Drive, Suite 200 San Diego, California

January 30, 2018 EX-99.1

10628 Science Center Drive, Suite 200, San Diego, California 92121 Tel: (858) 900-2660 ARCTURUS THERAPEUTICS Announces EXTRAORDINARY General Meeting of Shareholders

Exhibit 99.1 10628 Science Center Drive, Suite 200, San Diego, California 92121 Tel: (858) 900-2660 ARCTURUS THERAPEUTICS Announces EXTRAORDINARY General Meeting of Shareholders San Diego, California, January 30, 2018?Arcturus Therapeutics Ltd., or Arcturus (NASDAQ: ARCT), an RNA medicines company, today announced that it will hold an extraordinary general meeting of shareholders on Monday, Februa

January 24, 2018 6-K

ADHD / Alcobra Ltd. FORM 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: January 2018 (Report No. 1) Commission file number: 001-35932 ARCTURUS THERAPEUTICS LTD. (Translation of registrant?s name into English) 10628 Science Center Drive, Suite 200 San Diego, Califo

January 19, 2018 SC 13D

ARCT / Arcturus Therapeutics Ltd. / Sorenson Bradley T. - SCHEDULE 13D Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) (Amendment No. )1 Arcturus Therapeutics Ltd. (Name of Issuer) Ordinary Shares, par value of NIS 0.01 (Title of Class of Securities) M1492T105 (CUSIP Number) bradley thoma

January 10, 2018 SC 13D/A

ARCT / Arcturus Therapeutics Ltd. / Brosh Capital Partners L.p. - AMENDMENT NO. 10 TO THE SCHEDULE 13D Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) (Amendment No. 10)1 Arcturus Therapeutics Ltd. (Name of Issuer) Ordinary Shares, par value of NIS 0.01 (Title of Class of Securities) M1492T105 (CUSIP Number) Amir Efrati

December 11, 2017 SC 13G/A

ARCT / Arcturus Therapeutics Ltd. / FRANKLIN RESOURCES INC Passive Investment

arct17a2.htm - Generated by SEC Publisher for SEC Filing CUSIP NO. M1492T105 13G Page 1 of 14 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* ARCTURUS THERAPEUTICS LTD. (Name of Issuer) Ordinary Shares, par value NIS 0.01 per share (Title of Class of Securities) M1492T105 (CUSIP Number) November 30, 2

November 30, 2017 EX-99.1

Arcturus Therapeutics, Inc. 2013 Equity Incentive Plan

EX-99.1 5 tv480453ex99-1.htm EXHIBIT 99.1 Exhibit 99.1 2013 EQUITY INCENTIVE PLAN OF ARCTURUS THERAPEUTICS, INC. Adopted June 26, 2013 TABLE OF CONTENTS Page 1. GENERAL 1 2. DEFINITIONS 1 3. ADMINISTRATION 5 4. SHARES SUBJECT TO THE PLAN 7 5. ELIGIBILITY 8 6. OPTION AGREEMENT PROVISIONS 8 7. PROVISIONS OF STOCK AWARDS OTHER THAN OPTIONS 12 8. COVENANTS OF THE COMPANY 13 9. USE OF PROCEEDS 13 10. A

November 30, 2017 EX-4.1

Articles of Association of the Company. Incorporated by reference to Exhibit No. 4.1 to the Company’s Registration Statement on Form S-8 filed on November 30, 2017 (File No. 333-221830)

EX-4.1 2 tv480453ex4-1.htm EXHIBIT 4.1 Exhibit 4.1 Articles of Association of Arcturus Therapeutics Ltd. A Company Limited by Shares Under The Companies Law, 5759-1999 Chapter 1 General 1 Chapter 2 Shares and Share Capital 2 Chapter 3 General Meetings 5 Chapter 4 The Board of Directors 7 Chapter 5 Committees of the Board of Directors 10 Chapter 6 General Manager 11 Chapter 7 Exemption, Insurance,

November 30, 2017 S-8

ADHD / Alcobra Ltd. FORM S-8

As filed with the Securities and Exchange Commission on November 30, 2017 Registration No.

November 20, 2017 EX-99.1

JOINT FILING AGREEMENT

Exhibit 99.1 JOINT FILING AGREEMENT In accordance with Rule 13d-1(k)(1)(iii) under the Securities Exchange Act of 1934, as amended, the persons named below agree to the joint filing on behalf of each of them of a Statement on Schedule 13D (including amendments thereto) with respect to the shares of Ordinary Shares, par value of NIS 0.01, of Arcturus Therapeutics Ltd., an Israeli corporation. This

November 20, 2017 SC 13D/A

ARCT / Arcturus Therapeutics Ltd. / Brosh Capital Partners L.p. - AMENDMENT NO. 9 TO THE SCHEDULE 13D Activist Investment

SC 13D/A 1 sc13da91124700211202017.htm AMENDMENT NO. 9 TO THE SCHEDULE 13D UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) (Amendment No. 9)1 Arcturus Therapeutics Ltd. (Name of Issuer) Ordinary Shares, par value of NI

November 16, 2017 6-K

ADHD / Alcobra Ltd. FORM 6-K (Current Report of Foreign Issuer)

6-K 1 tv4797266k.htm FORM 6-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: November 2017 (Report No. 4) Commission file number: 001-35932 ARCTURUS THERAPEUTICS LTD. (Translation of registrant’s name into English) 10628 Science Center Dri

November 16, 2017 EX-99.1

Arcturus Therapeutics Announces Completion of Merger with Alcobra Ltd. and Commences Trading on the Nasdaq Global Market

Exhibit 99.1 Arcturus Therapeutics Announces Completion of Merger with Alcobra Ltd. and Commences Trading on the Nasdaq Global Market ? Combined Company Commences Trading on the Nasdaq Global Market on November 16, 2017 under the Ticker Symbol ?ARCT? ? Approximately $50.1 Million in Net Cash Following Closing of the Merger ? Ten (10) Pipeline Programs, Six (6) of Which Are Externally Funded by Pha

November 13, 2017 6-K

ADHD / Alcobra Ltd. FORM 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: November 2017 (Report No. 3) Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant's name into English) Azrieli Triangle Building 132 Derech Menachem Begin 39th Floor Tel A

November 9, 2017 6-K

ADHD / Alcobra Ltd. FORM 6-K (Current Report of Foreign Issuer)

6-K 1 tv4790676k.htm FORM 6-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: November 2017 (Report No. 2) Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant’s name into English) Azrieli Triangle Building 132 Derech M

November 9, 2017 EX-99.1

ALCOBRA ANNOUNCES THIRD QUARTER 2017 FINANCIAL RESULTS AND PROVIDES CORPORATE UPDATE

Exhibit 99.1 Investor Contacts Alcobra Investor Relations [email protected] ALCOBRA ANNOUNCES THIRD QUARTER 2017 FINANCIAL RESULTS AND PROVIDES CORPORATE UPDATE Tel Aviv, Israel ? November 9, 2017 ? Alcobra Ltd. (NasdaqGM: ADHD) today announced financial results for the three and nine months ended September 30, 2017, and provided a corporate update. Third Quarter and Recent Corporate Updates:

November 7, 2017 6-K

ADHD / Alcobra Ltd. FORM 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: November 2017 Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant's name into English) Azrieli Triangle Building 132 Derech Menachem Begin 39th Floor Tel Aviv 6701101 Isr

October 20, 2017 6-K

Alcobra FORM 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: October 2017 (Report No. 2) Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant's name into English) Azrieli Triangle Building 132 Derech Menachem Begin 39th Floor Tel Av

October 20, 2017 6-K

Alcobra FORM 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: October 2017 Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant's name into English) Azrieli Triangle Building 132 Derech Menachem Begin 39th Floor Tel Aviv 6701101 Isra

October 20, 2017 EX-99.1

ALCOBRA LTD. AMENDED NOTICE OF EXTRAORDINARY GENERAL MEETING OF SHAREHOLDERS

Exhibit 99.1 ALCOBRA LTD. AMENDED NOTICE OF EXTRAORDINARY GENERAL MEETING OF SHAREHOLDERS Background On October 28, 2017, Alcobra Ltd. (the “Company”) furnished to the Securities and Exchange Commission (“SEC”) a notice of extraordinary general meeting of shareholders (the “Original Notice”). This amended notice of extraordinary general meeting of shareholders amended and restates the Original Not

October 20, 2017 EX-99.2

ALCOBRA LTD. TEL AVIV, ISRAEL PROXY STATEMENT EXTRAORDINARY GENERAL MEETING OF SHAREHOLDERS

Exhibit 99.2 ALCOBRA LTD. TEL AVIV, ISRAEL PROXY STATEMENT EXTRAORDINARY GENERAL MEETING OF SHAREHOLDERS This Proxy Statement is furnished to the holders of ordinary shares, NIS 0.01 par value per share (?Ordinary Shares?), of Alcobra Ltd. (?Alcobra? or the ?Company?) in connection with the solicitation by the Board of Directors of Alcobra (the ?Board?) of proxies for use at Alcobra?s Extraordinar

October 20, 2017 EX-99.3

Fitch Proof 90719_CST_Alcobra_Proxy Card Front

Exhibit 99.3 Fitch Proof 90719CSTAlcobraProxy Card Front YOUR VOTE IS IMPORTANT. PLEASE VOTE TODAY. 2017 Extraordinary General Meeting of Shareholders of Alcobra Ltd. November 2, 2017, 10:00 am Israel time This Proxy is Solicited On Behalf Of The Board Of Directors PLEASE SIGN, DATE AND RETURN PROMPTLY IN THE ENCLOSED ENVELOPE. Please mark your votes like this X PROXY To approve certain resolution

September 28, 2017 6-K

Alcobra FORM 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: September 2017 (Report No. 3) Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant's name into English) Azrieli Triangle Building 132 Derech Menachem Begin 39th Floor Tel

September 28, 2017 EX-99.1

ALCOBRA LTD. NOTICE OF EXTRAORDINARY GENERAL MEETING OF SHAREHOLDERS

Exhibit 99.1 ALCOBRA LTD. NOTICE OF EXTRAORDINARY GENERAL MEETING OF SHAREHOLDERS Notice is hereby given that an Extraordinary General Meeting of the Shareholders of Alcobra Ltd. (the ?Company?) will be held on November 2, 2017, at 10:00 am (Israel Time), at the offices of the Company?s counsel (Zysman, Aharoni, Gayer & Co.) at ?Beit Zion?, 41-45 Rothschild Blvd., 8th Fl., Tel Aviv 6578401, Israel

September 28, 2017 EX-99.2

AGREEMENT AND PLAN OF MERGER AND REORGANIZATION ALCOBRA LTD. an Israeli company; ALEPH MERGERSUB, INC., and ARCTURUS THERAPEUTICS, INC. Dated as of September 27, 2017 Table of Contents

Exhibit 99.2 AGREEMENT AND PLAN OF MERGER AND REORGANIZATION among ALCOBRA LTD. an Israeli company; ALEPH MERGERSUB, INC., and ARCTURUS THERAPEUTICS, INC. Dated as of September 27, 2017 Table of Contents Page Article 1 DESCRIPTION OF TRANSACTION 3 1.1 Structure of the Merger 3 1.2 Effects of the Merger 3 1.3 Closing; Effective Time 3 1.4 Certificate of Incorporation and Bylaws; Directors and Offic

September 28, 2017 EX-99.3

Arcturus Therapeutics / Alcobra Merger Enabling a New Era of RNA Medicines September 28, 2017

Exhibit 99.3 Arcturus Therapeutics / Alcobra Merger Enabling a New Era of RNA Medicines September 28, 2017 Forward Looking Statements This presentation contains forward - looking statements. These statements relate to future events and involve known and unknown risks, uncertainties and other factors which may cause our actual results, performance or achievements to be materially diffe ren t from a

September 28, 2017 EX-99.1

Alcobra Ltd. and Arcturus Therapeutics, Inc. Agree to Merge

Exhibit 99.1 Alcobra Ltd. and Arcturus Therapeutics, Inc. Agree to Merge ? Transaction to result in NASDAQ-listed company focused on developing novel RNA medicines and technologies ? Arcturus brings a proprietary and diverse pipeline with seven programs, four of which are funded by pharmaceutical and strategic partners ? Plan to accelerate development of internal programs targeting rare diseases ?

September 28, 2017 6-K

Alcobra FORM 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: September 2017 (Report No. 2) Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant?s name into English) Azrieli Triangle Building 132 Derech Menachem Begin 39th Floor Tel

September 14, 2017 EX-99.1

ALCOBRA LTD. NOTICE OF ANNUAL AND EXTRAORDINARY GENERAL MEETING OF SHAREHOLDERS

Exhibit 99.1 ALCOBRA LTD. NOTICE OF ANNUAL AND EXTRAORDINARY GENERAL MEETING OF SHAREHOLDERS Notice is hereby given that an Annual and Extraordinary General Meeting of the Shareholders of Alcobra Ltd. (?Alcobra?) will be held on October 19, 2017, at 10:00 am (Israel Time), at the offices of Alcobra?s counsel (Zysman, Aharoni, Gayer & Co.) at ?Beit Zion?, 41-45 Rothschild Blvd., 8th Fl., Tel Aviv 6

September 14, 2017 6-K

Alcobra FORM 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: September 2017 Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant?s name into English) Azrieli Triangle Building 132 Derech Menachem Begin 39th Floor Tel Aviv 6701101 Is

August 11, 2017 EX-99.1

ALCOBRA ANNOUNCES SECOND QUARTER 2017 FINANCIAL RESULTS AND PROVIDES CORPORATE UPDATE

Exhibit 99.1 Investor Contacts Alcobra Investor Relations [email protected] ALCOBRA ANNOUNCES SECOND QUARTER 2017 FINANCIAL RESULTS AND PROVIDES CORPORATE UPDATE Tel Aviv, Israel ? August 11, 2017 ? Alcobra Ltd. (NasdaqGM: ADHD) today announced financial results for the three and six months ended June 30, 2017, and provided a corporate update. Second Quarter and Recent Corporate Updates: ? On

August 11, 2017 6-K

Alcobra FORM 6-K (Current Report of Foreign Issuer)

6-K 1 v4730296k.htm FORM 6-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: August 2017 Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant’s name into English) Azrieli Triangle Building 132 Derech Menachem Begin 39th

July 3, 2017 EX-99.1

Irrevocable Resignation Letter

EX-99.1 2 ex991to13da811247002062917.htm COOPERATION AGREEMENT Exhibit 99.1 June 12, 2017 Reference is made to: (i) the agreement (the “Settlement Agreement”) between Alcobra Ltd. (the “Company”) and Brosh Capital Partners L.P. (formerly named Exodus Capital L.P.), Brosh Capital L.P., Amir Efrati and Asaf Frumerman, of May 5, 2017, which was also approved by the Economic Division of the District C

July 3, 2017 SC 13D/A

ARCT / Arcturus Therapeutics Ltd. / Brosh Capital Partners L.p. - AMENDMENT NO. 8 TO THE SCHEDULE 13D Activist Investment

SC 13D/A 1 sc13da81124700206292017.htm AMENDMENT NO. 8 TO THE SCHEDULE 13D UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) (Amendment No. 8)1 Alcobra Ltd. (Name of Issuer) Ordinary Shares, par value of NIS 0.01 (Title

June 23, 2017 6-K

Alcobra 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: June 2017 (Report No. 2) Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant?s name into English) Azrieli Triangle Building 132 Derech Menachem Begin 39th Floor Tel Aviv

June 23, 2017 EX-99.1

Alcobra Updates on its Review of Strategic Alternatives

EX-99.1 2 v469537ex99-1.htm EXHIBIT 99.1 Exhibit 99.1 Alcobra Updates on its Review of Strategic Alternatives TEL AVIV, Israel, June 23, 2017 - Alcobra Ltd. (Nasdaq: ADHD), an emerging pharmaceutical company focused on the development of new medications to treat significant unmet clinical needs, today announced that its Board of Directors is conducting a process to explore and review a range of st

June 12, 2017 EX-99.2

Irrevocable Resignation Letter

Exhibit 99.2 June 12, 2017 Reference is made to: (i) the agreement (the ?Settlement Agreement?) between Alcobra Ltd. (the ?Company?) and Brosh Capital Partners L.P. (formerly named Exodus Capital L.P.), Brosh Capital L.P., Amir Efrati and Asaf Frumerman, of May 5, 2017, which was also approved by the Economic Division of the District Court of Tel Aviv (the ?Court?), and (ii) the letter from Brosh

June 12, 2017 EX-99.1

Alcobra Announces Cooperation Agreement with Brosh Group and Board Additions Company Adds Two Directors to the Board Company to Continue Strategic Alternatives Process to Maximize Value for All Shareholders

Exhibit 99.1 Alcobra Announces Cooperation Agreement with Brosh Group and Board Additions Company Adds Two Directors to the Board Company to Continue Strategic Alternatives Process to Maximize Value for All Shareholders TEL AVIV, Israel, June 12, 2017 - Alcobra Ltd. (Nasdaq: ADHD), an emerging pharmaceutical company focused on the development of new medications to treat significant unmet clinical

June 12, 2017 6-K

Alcobra FORM 6-K (Current Report of Foreign Issuer)

6-K 1 v4688176k.htm FORM 6-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: June 2017 Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant's name into English) Azrieli Triangle Building 132 Derech Menachem Begin 39th F

May 30, 2017 EX-99.1

ALCOBRA ANNOUNCES FIRST QUARTER 2017 FINANCIAL RESULTS AND PROVIDES CORPORATE UPDATE

Exhibit 99.1 Investor Contacts Alcobra Investor Relations [email protected] ALCOBRA ANNOUNCES FIRST QUARTER 2017 FINANCIAL RESULTS AND PROVIDES CORPORATE UPDATE Tel Aviv, Israel – May 30, 2017 – Alcobra Ltd. (NasdaqGM: ADHD) today announced financial results for the three months ended March 31, 2017, and provided a corporate update. First Quarter and Recent Corporate Updates: · Alcobra recentl

May 30, 2017 6-K

Alcobra 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: May 2017 (Report No. 3) Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant's name into English) Azrieli Triangle Building 132 Derech Menachem Begin 39th Floor Tel Aviv 6

May 15, 2017 EX-99.1

Alcobra Announces Leadership Update Dr. Yaron Daniely to Step Down as Chief Executive Officer, Effective May 31, 2017 David Baker Named Interim Chief Executive Officer Dr. Daniely to Remain on Board of Directors and be Appointed Chairman

EX-99.1 2 v467020ex99-1.htm EXHIBIT 99.1 Exhibit 99.1 Alcobra Announces Leadership Update Dr. Yaron Daniely to Step Down as Chief Executive Officer, Effective May 31, 2017 David Baker Named Interim Chief Executive Officer Dr. Daniely to Remain on Board of Directors and be Appointed Chairman TEL AVIV, Israel, May 15, 2017 - Alcobra Ltd. (Nasdaq: ADHD), an emerging pharmaceutical company focused on

May 15, 2017 6-K

Alcobra 6-K (Current Report of Foreign Issuer)

6-K 1 v4670206k.htm 6-K REPORT OF FOREIGN PRIVATE ISSUER UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: May 2017 (Report No. 2) Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant’s name into English) Azrieli Triangle

May 9, 2017 EX-99.1

JOINT FILING AGREEMENT

Exhibit 99.1 JOINT FILING AGREEMENT In accordance with Rule 13d-1(k)(1)(iii) under the Securities Exchange Act of 1934, as amended, the persons named below agree to the joint filing on behalf of each of them of a Statement on Schedule 13D (including amendments thereto) with respect to the shares of Ordinary Shares, par value of NIS 0.01, of Alcobra Ltd. This Joint Filing Agreement shall be filed a

May 9, 2017 SC 13D/A

ARCT / Arcturus Therapeutics Ltd. / Brosh Capital Partners L.p. - AMENDMENT NO. 7 TO THE SCHEDULE 13D Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) (Amendment No. 7)1 Alcobra Ltd. (Name of Issuer) Ordinary Shares, par value of NIS 0.01 (Title of Class of Securities) M2239P 10 9 (CUSIP Number) Amir Efrati Brosh Capita

May 5, 2017 EX-99.1

Alcobra Provides Update on Cancellation of Extraordinary Meeting Called by Brosh Group

Exhibit 99.1 Alcobra Provides Update on Cancellation of Extraordinary Meeting Called by Brosh Group TEL AVIV, Israel, May 5, 2017 ? Alcobra Ltd. (Nasdaq: ADHD), an emerging pharmaceutical company focused on the development of new medications to treat significant unmet clinical needs, today announced that it has reached an agreement (the ?Agreement") with Brosh Capital L.P. and certain of its affil

May 5, 2017 6-K

Alcobra FORM 6-K (Current Report of Foreign Issuer)

6-K 1 v4662706k.htm FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: May 2017 Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant’s name into English) Azrieli Triangle Building

April 28, 2017 S-8

Alcobra FORM S-8

S-8 1 v465188s8.htm FORM S-8 As filed with the Securities and Exchange Commission on April 28, 2017 Registration No. 333- United States SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 alcobra ltd. (Exact name of registrant as specified in its charter) State of Israel (State or other jurisdiction of incorporation or organiza

April 28, 2017 20-F

Alcobra 20-F

20-F 1 v46395520f.htm 20-F UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 20-F ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2016 Commission file number: 001-35932 Alcobra Ltd. (Exact name of Registrant as specified in its charter) State of Israel (Jurisdiction of incorporation or organizati

April 27, 2017 6-K

Alcobra FORM 6-K (Current Report of Foreign Issuer)

6-K 1 v4653776k.htm FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: April 2017 (Report No. 3) Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant’s name into English) Azrieli T

April 24, 2017 EX-99.1

ALCOBRA LTD. TEL-AVIV, ISRAEL

Exhibit 99.1 ALCOBRA LTD. TEL-AVIV, ISRAEL Dear Shareholder: Brosh Capital L.P., Exodus Capital L.P., Exodus Management Israel Ltd. and Amir Efrati (together, the ?Brosh Group?) have called an extraordinary general meeting of shareholders (the ?Extraordinary General Meeting?) of Alcobra Ltd. (the ?Company? or ?Alcobra?) seeking among other things to remove and replace the entire Board of Directors

April 24, 2017 6-K

Alcobra REPORT OF FOREIGN PRIVATE ISSUER (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: April 2017 (Report No. 2) Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant?s name into English) Azrieli Triangle Building 132 Derech Menachem Begin 39th Floor Tel Aviv

April 24, 2017 EX-99.2

Alcobra Mails Proxy Materials for Extraordinary General Meeting of Shareholders The Board Will Defend Shareholders from Opportunistic Takeover of the Company Believes Brosh Capital’s Request Does Not Comply With Alcobra’s Articles of Association

Exhibit 99.2 Alcobra Mails Proxy Materials for Extraordinary General Meeting of Shareholders The Board Will Defend Shareholders from Opportunistic Takeover of the Company Believes Brosh Capital’s Request Does Not Comply With Alcobra’s Articles of Association TEL AVIV, Israel, April 24, 2017 - Alcobra Ltd. (Nasdaq:ADHD), an emerging pharmaceutical company focused on the development of new medicatio

April 12, 2017 SC 13D/A

ARCT / Arcturus Therapeutics Ltd. / Brosh Capital Partners L.p. - AMENDMENT NO. 6 TO THE SCHEDULE 13D Activist Investment

SC 13D/A 1 sc13da61124700204112017.htm AMENDMENT NO. 6 TO THE SCHEDULE 13D UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) (Amendment No. 6)1 Alcobra Ltd. (Name of Issuer) Ordinary Shares, par value of NIS 0.01 (Title

April 12, 2017 EX-99.1

Brosh Capital is summoning an Extraordinary General Meeting [References: Brosh Capital LP and Exodus Capital LP letter dated Marth 16th, 2017 (the "Request Letter") and The Company's letter dated April 5th, 2017 ("Response Letter")]

Exhibit 99.1 April 12, 2017 To: Alcobra Ltd ("The Company") 132 Derech Menachem Begin Tel-Aviv 6701101 Brosh Capital is summoning an Extraordinary General Meeting [References: Brosh Capital LP and Exodus Capital LP letter dated Marth 16th, 2017 (the "Request Letter") and The Company's letter dated April 5th, 2017 ("Response Letter")] We hereby confirm receipt of your letter dated April 5th, 2017,

April 12, 2017 EX-99.2

NOTICE OF EXTRAORDINARY GENERAL MEETING OF SHAREHOLDERS OF ALCOBRA LTD.

Exhibit 99.2 NOTICE OF EXTRAORDINARY GENERAL MEETING OF SHAREHOLDERS OF ALCOBRA LTD. On March 16th, 2017 Brosh Capital L.P. and Exodus Capital L.P., (shareholders holding approximately 17% of the voting rights in the Company) ("The Shareholders"), requested Alcobra Ltd's. (“Company”) board of directors to convene an extraordinary meeting of the shareholders of the Company, in accordance with secti

April 10, 2017 SC 13D/A

Alcobra AMENDMENT NO. 5 TO THE SCHEDULE 13D (Activist Acquisition of More Than 5% of Shares)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO ? 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO ? 240.13d-2(a) (Amendment No. 5)1 Alcobra Ltd. (Name of Issuer) Ordinary Shares, par value of NIS 0.01 (Title of Class of Securities) M2239P 10 9 (CUSIP Number) Amir Efrati Exodus Capit

April 5, 2017 6-K

Alcobra FORM 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: April 2017 Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant's name into English) Azrieli Triangle Building 132 Derech Menachem Begin 39th Floor Tel Aviv 6701101 Israel

April 5, 2017 EX-99.1

Alcobra Provides Update on Request for Extraordinary General Meeting Brosh Capital’s Request Does Not Comply With Alcobra’s Articles of Association Company Addresses Brosh Capital’s Misinformed Views

Exhibit 99.1 Alcobra Provides Update on Request for Extraordinary General Meeting Brosh Capital?s Request Does Not Comply With Alcobra?s Articles of Association Company Addresses Brosh Capital?s Misinformed Views TEL AVIV, Israel ? April 5, 2017 ? Alcobra Ltd. (Nasdaq: ADHD), an emerging pharmaceutical company focused on the development of new medications to treat CNS and cognitive disorders, toda

April 4, 2017 EX-99.1

JOINT FILING AGREEMENT

EX-99.1 2 ex991to13da411247002040417.htm JOINT FILING AGREEMENT Exhibit 99.1 JOINT FILING AGREEMENT In accordance with Rule 13d-1(k)(1)(iii) under the Securities Exchange Act of 1934, as amended, the persons named below agree to the joint filing on behalf of each of them of a Statement on Schedule 13D (including amendments thereto) with respect to the shares of Ordinary Shares, par value of NIS 0.

April 4, 2017 SC 13D/A

ARCT / Arcturus Therapeutics Ltd. / Brosh Capital L.P. - AMENDMENT NO. 4 TO THE SCHEDULE 13D Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) (Amendment No. 4)1 Alcobra Ltd. (Name of Issuer) Ordinary Shares, par value of NIS 0.01 (Title of Class of Securities) M2239P 10 9 (CUSIP Number) Amir Efrati Exodus Capit

March 27, 2017 SC 13D/A

ARCT / Arcturus Therapeutics Ltd. / Brosh Capital L.P. - AMENDMENT NO. 3 TO THE SCHEDULE 13D Activist Investment

SC 13D/A 1 sc13da31124700203272017.htm AMENDMENT NO. 3 TO THE SCHEDULE 13D UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) (Amendment No. 3)1 Alcobra Ltd. (Name of Issuer) Ordinary Shares, par value of NIS 0.01 (Title

March 16, 2017 SC 13D/A

ARCT / Arcturus Therapeutics Ltd. / Brosh Capital L.P. - AMENDMENT NO. 2 TO THE SCHEDULE 13D Activist Investment

SC 13D/A 1 sc13da21124700203162017.htm AMENDMENT NO. 2 TO THE SCHEDULE 13D UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) (Amendment No. 2)1 Alcobra Ltd. (Name of Issuer) Ordinary Shares, par value of NIS 0.01 (Title

March 16, 2017 EX-99.1

BROSH CAPITAL L.P. 11 Menachem Begin Rd. Ramat-Gan, Israel 5268104

Exhibit 99.1 BROSH CAPITAL L.P. 11 Menachem Begin Rd. Ramat-Gan, Israel 5268104 [email protected] March 16, 2017 Alcobra Ltd. Azrieli Triangle Building 132 Derech Menachem Begin 39th Floor Tel Aviv 6701101 Israel Attn: Howard B. Rosen, Chairman of the Board of Directors Dear Mr. Rosen, Brosh Capital L.P., together with its affiliates (collectively, “Brosh”), are the beneficial owners of appr

February 24, 2017 SC 13D/A

ARCT / Arcturus Therapeutics Ltd. / Brosh Capital L.P. - AMENDMENT NO. 1 TO THE SCHEDULE 13D Activist Investment

SC 13D/A 1 sc13da11124700202242017.htm AMENDMENT NO. 1 TO THE SCHEDULE 13D UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) (Amendment No. 1)1 Alcobra Ltd. (Name of Issuer) Ordinary Shares, par value of NIS 0.01 (Title

February 15, 2017 6-K

Alcobra FORM 6-K (Current Report of Foreign Issuer)

6-K 1 v4597066k.htm FORM 6-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: February 2017 (Report No. 2) Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant's name into English) Azrieli Triangle Building 132 Derech Me

February 15, 2017 EX-99.1

ALCOBRA ANNOUNCES FOURTH-QUARTER AND FULL-YEAR 2016 FINANCIAL RESULTS AND PROVIDES CORPORATE UPDATE

Exhibit 99.1 Investor Contacts Alcobra Investor Relations Debbie Kaye US: 212-390-8964, Intl: +972-3-7299871 [email protected] ALCOBRA ANNOUNCES FOURTH-QUARTER AND FULL-YEAR 2016 FINANCIAL RESULTS AND PROVIDES CORPORATE UPDATE Conference Call & Webcast February 15th at 8:30 a.m. Eastern Time/5:30 a.m. Pacific Time Tel Aviv, Israel ? February 15, 2017 ? Alcobra Ltd. (NasdaqGM: ADHD), an emergin

February 14, 2017 SC 13G/A

ARCT / Arcturus Therapeutics Ltd. / VENROCK HEALTHCARE CAPITAL PARTNERS LP - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 2)* ALCOBRA LTD. (Name of Issuer) ORDINARY SHARES (Title of Class of Securities) M2239P109 (CUSIP Number) December 31, 2016 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Sched

February 14, 2017 SC 13G/A

Alcobra 3G/A (Passive Acquisition of More Than 5% of Shares)

SC 13G/A 1 c8742413ga.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G/A (Amendment No. 2) Under the Securities Exchange Act of 1934* Alcobra Ltd. (Name of Issuer) Ordinary Shares (Title of Class of Securities) M2239P109 (CINS Number) December 31, 2016 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pur

February 14, 2017 SC 13G/A

Alcobra FEBRUARY 14, 2017 (Passive Acquisition of More Than 5% of Shares)

SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G (RULE 13D - 102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO 13d-1(b), (c) AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO 13d-2(b) (Amendment No. 2 )* Alcobra Ltd. (Name of Issuer) Ordinary Shares, par value NIS $0.01 per share (Title of Class of Securities) M2239P109 (CUSIP Number) December 31, 2016 (Date of E

February 14, 2017 SC 13G/A

ARCT / Arcturus Therapeutics Ltd. / Knoll Capital Management, LP - SCHEDULE 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G* (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b), (c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2 (Amendment No. 1)* Alcobra Ltd, (Name of Issuer) Common Stock, $0.01 par value per share (Title of Class of Securities) M2239P109 (CUSIP Number) December 31, 2

February 13, 2017 SC 13G/A

ARCT / Arcturus Therapeutics Ltd. / Broadfin Capital, LLC Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No.

February 6, 2017 6-K

Alcobra FORM 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: February 2017 Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant’s name into English) Azrieli Triangle Building 132 Derech Menachem Begin 39th Floor Tel Aviv 6701101 Isr

February 6, 2017 EX-99.1

Alcobra Reports on Productive FDA Meeting for New Lead Product Candidate for ADHD

Exhibit 99.1 Alcobra Reports on Productive FDA Meeting for New Lead Product Candidate for ADHD ? Pre-IND meeting held on Alcobra?s proprietary Abuse-Deterrent, Amphetamine Immediate Release (ADAIR) product candidate. ? Meeting defined a 505(b)(2) development path, to be funded with existing cash balance, and targeting a 2H 2018 NDA submission ? Investor call to be held on February 7, 2017 at 8:30

February 2, 2017 EX-99.1

JOINT FILING AGREEMENT

EX-99.1 2 e615710ex99-1.htm JOINT FILING AGREEMENT Exhibit 99.1 JOINT FILING AGREEMENT In accordance with Rule 13d-1(k)(1)(iii) under the Securities Exchange Act of 1934, as amended, the persons named below agree to the joint filing on behalf of each of them of a Statement on Schedule 13D (including amendments thereto) with respect to the shares of Ordinary Shares, par value of NIS 0.01, of Alcobr

February 2, 2017 SC 13D

ARCT / Arcturus Therapeutics Ltd. / Brosh Capital L.P. - THE SCHEDULE 13D Activist Investment

SC 13D 1 e615710sc13d-alcobra.htm THE SCHEDULE 13D UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D (Rule 13d-101) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO § 240.13d-1(a) AND AMENDMENTS THERETO FILED PURSUANT TO § 240.13d-2(a) (Amendment No. )1 Alcobra Ltd. (Name of Issuer) Ordinary Shares, par value of NIS 0.01 (Title of Class of Securities) M

January 17, 2017 6-K

Alcobra 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: January 2017 (Report No. 2) Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant's name into English) Azrieli Triangle Building 132 Derech Menachem Begin 39th Floor Tel Av

January 17, 2017 EX-99.1

Alcobra Reports Phase 3 Clinical Trial of MDX in Adults with ADHD Missed Primary Endpoint - Management to hold a conference call & webcast today, January 17th at 8:00 a.m. EST

Exhibit 99.1 Investor Contacts Alcobra Investor Relations Debbie Kaye US: 212-8908964, Intl: +972-3-7299871 [email protected] Alcobra Reports Phase 3 Clinical Trial of MDX in Adults with ADHD Missed Primary Endpoint - Management to hold a conference call & webcast today, January 17th at 8:00 a.m. EST Tel Aviv, Israel ? January 17, 2017 ? Alcobra Ltd. (NasdaqGM: ADHD), an emerging pharmaceutica

January 9, 2017 EX-99.1

Alcobra Provides Update on Recent FDA Meeting and Path Forward for MDX Clinical Development Program - Alcobra and FDA agree on review of available data from the Phase 3 MEASURE study in a future NDA submission - Top-line results from the MEASURE stud

Exhibit 99.1 Investor Contacts Alcobra Investor Relations Debbie Kaye US: 212-8908964, Intl: +972-3-7299871 [email protected] Alcobra Provides Update on Recent FDA Meeting and Path Forward for MDX Clinical Development Program - Alcobra and FDA agree on review of available data from the Phase 3 MEASURE study in a future NDA submission - Top-line results from the MEASURE study to be reported in

January 9, 2017 6-K

Alcobra FORM 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: January 2017 Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant's name into English) Azrieli Triangle Building 132 Derech Menachem Begin 39th Floor Tel Aviv 6701101 Isra

November 15, 2016 EX-99.1

ALCOBRA ANNOUNCES THIRD QUARTER 2016 FINANCIAL RESULTS AND PROVIDES CORPORATE UPDATE

Exhibit 99.1 U.S. Investor Contacts Media Inquiries Israel Investor Contact: LifeSci Advisors, LLC Sam Brown, Inc. Alcobra Investor Relations Michael Rice Mike Beyer Debbie Kaye 646-597-6979 312-961-2502 +972-72 2204661 [email protected] [email protected] [email protected] ALCOBRA ANNOUNCES THIRD QUARTER 2016 FINANCIAL RESULTS AND PROVIDES CORPORATE UPDATE ? Conference Call &

November 15, 2016 6-K

Alcobra FORM 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: November 2016 Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant's name into English) Azrieli Triangle Building 132 Derech Menachem Begin 39th Floor Tel Aviv 6701101 Isr

November 9, 2016 SC 13G/A

Alcobra 3G/A (Passive Acquisition of More Than 5% of Shares)

alco16a1.htm - Generated by SEC Publisher for SEC Filing CUSIP NO. M2239P109 13G Page 1 of 15 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Alcobra Ltd. (Name of Issuer) Ordinary Shares, par value NIS 0.01 per share (Title of Class of Securities) M2239P109 (CUSIP Number) October 31, 2016 (Date of Ev

October 21, 2016 SC 13G/A

Alcobra SC 13G/A (Passive Acquisition of More Than 5% of Shares)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* ALCOBRA LTD. (Name of Issuer) Ordinary Shares (Title of Class of Securities) M2239P109 (CUSIP Number) October 13, 2016 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule

October 7, 2016 EX-99.1

Update from Alcobra on Recent FDA Communications

Exhibit 99.1 U.S. Investor Contacts Media Inquiries Israel Investor Contact: LifeSci Advisors, LLC Sam Brown, Inc. Alcobra Investor Relations Michael Rice Mike Beyer Debbie Kaye 646-597-6979 773-463-4211 +972-72 2204661 [email protected] [email protected] [email protected] Update from Alcobra on Recent FDA Communications Tel Aviv, Israel ? October 7, 2016 ? Alcobra Ltd. (Nasda

October 7, 2016 6-K

Alcobra FORM 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: October 2016 Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant's name into English) Azrieli Triangle Building 132 Derech Menachem Begin 39th Floor Tel Aviv 6701101 Isra

September 29, 2016 6-K

Alcobra FORM 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: September 2016 Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant's name into English) Azrieli Triangle Building 132 Derech Menachem Begin 39th Floor Tel Aviv 6701101 Is

September 29, 2016 EX-99.1

Alcobra Announces IND Clinical Hold Affecting the MDX Phase III MEASURE Study

Exhibit 99.1 U.S. Investor Contacts Media Inquiries Israel Investor Contact: LifeSci Advisors, LLC Sam Brown, Inc. Alcobra Investor Relations Michael Rice Mike Beyer Debbie Kaye 646-597-6979 773-463-4211 +972-72 2204661 [email protected] [email protected] [email protected] Alcobra Announces IND Clinical Hold Affecting the MDX Phase III MEASURE Study Tel Aviv, Israel ? Septembe

August 30, 2016 EX-99.1

ALCOBRA ANNOUNCES SECOND QUARTER 2016 FINANCIAL RESULTS AND PROVIDES CORPORATE UPDATE · Conference Call & Webcast August 30th at 8:30 a.m. Eastern Time/5:30 a.m. Pacific Time

Exhibit 99.1 U.S. Investor Contacts Media Inquiries Israel Investor Contact: LifeSci Advisors, LLC Sam Brown, Inc. Alcobra Investor Relations Michael Rice Mike Beyer Debbie Kaye 646-597-6979 773-463-4211 +972-72 2204661 [email protected] [email protected] [email protected] ALCOBRA ANNOUNCES SECOND QUARTER 2016 FINANCIAL RESULTS AND PROVIDES CORPORATE UPDATE ? Conference Call &

August 30, 2016 6-K

Alcobra FORM 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: August 2016 Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant's name into English) Azrieli Triangle Building 132 Derech Menachem Begin 39th Floor Tel Aviv 6701101 Israe

July 19, 2016 6-K

Alcobra FORM 6-K (Current Report of Foreign Issuer)

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: July 2016 (Report No. 2) Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant's name into English) Azrieli Triangle Building 132 Derech Menachem Begin 39th Floor Tel Aviv

July 19, 2016 EX-99.1

Alcobra Granted European Orphan Drug Designation for Metadoxine in Fragile X Syndrome

Exhibit 99.1 U.S. Investor Contacts Media Inquiries Israel Investor Contact: LifeSci Advisors, LLC Sam Brown, Inc. Alcobra Investor Relations Michael Rice Mike Beyer Debbie Kaye 646-597-6979 312-961-2502 +972-72 2204661 [email protected] [email protected] [email protected] Alcobra Granted European Orphan Drug Designation for Metadoxine in Fragile X Syndrome Tel Aviv, Israel ?

July 19, 2016 6-K

Alcobra FORM 6-K (Current Report of Foreign Issuer)

6-K 1 v4444826k.htm FORM 6-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form 6-K Report of Foreign Private Issuer Pursuant to Rule 13a-16 or 15d-16 under the Securities Exchange Act of 1934 For the month of: July 2016 Commission file number: 001-35932 ALCOBRA LTD. (Translation of registrant's name into English) Azrieli Triangle Building 132 Derech Menachem Begin 39th F

June 8, 2016 EX-99.1

ALCOBRA LTD. NOTICE OF ANNUAL GENERAL MEETING OF SHAREHOLDERS

Exhibit 99.1 ALCOBRA LTD. NOTICE OF ANNUAL GENERAL MEETING OF SHAREHOLDERS Notice is hereby given that an Annual General Meeting of the Shareholders of Alcobra Ltd. (?Company?) will be held on July 19, 2016, at 10:00 am (Israel Time), at the offices of the Company's counsel (Zysman, Aharoni, Gayer & Co.) at "Beit Zion", 41-45 Rothschild Blvd., 8th Fl., Tel Aviv 6578401, Israel (?Meeting?), for the

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